• Disease
  • Dna
  • Dna Ploidy
  • Arlene J Herzberg

    Prominent publications by Arlene J Herzberg

    KOL Index score: 8664

    We describe a 2 1/2-year-old boy who has hirsutism and ringed creases of the extremities associated with an underlying smooth muscle hamartoma. Cutaneous findings in this child resemble those in other reports of the "Michelin tire syndrome." Histologic examination showed numerous well-demarcated fascicles of smooth muscle cells randomly distributed at all levels of the reticular dermis with haphazard orientation. These cells were immunoreactive with desmin, which confirmed their smooth ...

    Also Ranks for: Michelin Tire Syndrome |  smooth muscle |  multiple anomalies |  chromosome 7 |  human pair
    KOL Index score: 7464

    BACKGROUND: A variant of basal cell carcinoma (BCC) with scattered large, pleomorphic cells has previously been reported as "basal cell epithelioma with giant tumor cells" and "basal cell carcinoma with monster cells."

    OBJECTIVE: Our purpose was to describe the clinical, histologic, and DNA ploidy findings in BCCs with these cytologic features.

    METHODS: Nineteen pleomorphic BCCs from 15 patients were prospectively collected, and other BCCs in these patients were retrospectively reviewed ...

    Also Ranks for: Basal Cell |  image analysis |  peripheral palisading |  cytologic features |  carcinoma bcc
    KOL Index score: 6696

    The distinction between the keratoacanthoma (KA) and the squamous cell carcinoma (SCC) can sometimes be difficult on the basis of histologic and clinical criteria. The possible diagnostic significance of DNA ploidy initiated the present study evaluating the DNA ploidy in paraffin-embedded tissue sections of 7 KA and 15 SCC, and fresh frozen tissue touch preparations of 15 of the same cases using the CAS 200 Image Analyzer. In paraffin-embedded tissue sections the main peak DNA index was ...

    Also Ranks for: Squamous Cell Carcinoma |  dna image |  keratoacanthoma ka |  embedded tissue |  skin neoplasms
    KOL Index score: 6194

    Adenoid cystic carcinoma (ACC) of the breast is a rare histologic type of breast cancer associated with a good prognosis. A woman who earlier had a pulmonary metastasis surgically resected 6 years postmastectomy developed clinically symptomatic bleeding from a renal metastasis 12 years postmastectomy. An atypical angiographic picture (moderate vascularization) for secondary renal neoplasms was observed. The characteristic histologic features of ACC were present in all specimens; ...

    Also Ranks for: Adenoid Cystic |  breast metastatic |  neoplasms carcinoma |  renal metastasis |  humans kidney
    KOL Index score: 4481

    Image analysis of DNA content was performed from single nuclei of melanoma monolayer imprints made from fresh frozen tissue of 14 patients with primary malignant melanoma and 16 patients with local recurrences at the incision site and local or distant metastases. This procedure requires fewer cells and is an advantage when the quantity of tumor available is limited, especially in thin low Breslow depth cutaneous melanomas. Image analysis allowed reproducible measurement of DNA ploidy ...

    Also Ranks for: Dna Ploidy |  image cytometry |  malignant melanoma |  embedded tissue |  primary metastatic
    KOL Index score: 4087

    Image analysis of nuclear DNA content (DNA ploidy) was performed on smears of basal cell carcinoma (BCC) obtained during Mohs microscopically-controlled surgery from 51 tumors. DNA ploidy was compared with histologic growth pattern and the contour of the invading edge. There was a statistically significantly increased frequency of DNA aneuploidy in smears from BCC exhibiting partial or total diffuse (infiltrative and superficial multicentric) growth patterns (80%; 32 of 40) as compared ...

    Also Ranks for: Dna Ploidy |  basal cell |  image analysis |  skin neoplasms |  flow cytometry
    KOL Index score: 3658

    We compared the damage resulting from intradermal injection of four commonly used radiographic contrast media in laboratory rats. Sixty percent meglumine diatrizoate (Reno M 60) and ioxaglate (Hexabrix) produced significantly more ulceration and crusting on gross inspection and more necrosis, edema, and hemorrhage on histologic evaluation than iopamidol 300 (Isovue) or 0.9% (normal) saline. Thirty percent meglumine diatrizoate (Reno M Dip) had an intermediate toxicity, resulting in ...

    Also Ranks for: Diagnostic Therapeutic |  osmolar agents |  contrast media |  necrosis edema |  meglumine diatrizoate
    KOL Index score: 3528

    BACKGROUND: An acquired port-wine stain is a rarely reported vascular lesion that mimics a congenital port-wine stain clinically, but is acquired after birth.

    METHODS: Clinical and histologic information concerning ten patients with acquired port-wine stains was recorded. Stains of seven of these patients were treated with either the copper vapor or pulsed dye laser.

    RESULTS: Collected information suggests that many acquired port-wine stains are idiopathic in nature. Light microscopic ...

    Also Ranks for: Wine Stains |  acquired port |  dye laser |  histologic findings |  facial dermatoses
    KOL Index score: 3104

    BACKGROUND: With increasing numbers of studies examining tumor DNA content in many organ systems, accumulating evidence indicates that DNA ploidy analysis may be useful in diagnosis and determination of prognosis.

    OBSERVATIONS: A review of DNA ploidy studies of cutaneous lesions within the last decade reveals that DNA ploidy may aid in the diagnosis of some lesions. Several studies show an association of DNA ploidy with prognosis. In general, tumors with a diploid DNA content have a less ...

    Also Ranks for: Dna Ploidy |  skin neoplasms |  flow cytometry |  background increasing


    Arlene J Herzberg: Influence Statistics

    Sample of concepts for which Arlene J Herzberg is among the top experts in the world.
    Concept World rank
    19 pleomorphic bccs #1
    pleomorphic bccs #1
    nonpleomorphic bcc #1
    nineteen pleomorphic bccs #1
    huge pleomorphic #1
    keloidalis chronic #2
    modalities granuloma #3
    acquired port‐wine #4
    inflammation hair follicle #4
    recurrent cyclic eruptions #4
    examination early lesions #4
    subfollicular destruction #4
    sebaceous glands etiology #4
    firm plaques nodules #4
    review acne keloidalis #4
    methods subfollicular destruction #4
    possibility cyclic nature #4
    acne keloidalis centers #4
    early lesions inflammation #4
    etiology acne keloidalis #4
    acne keloidalis review #4
    subfollicular destruction process #4
    acne keloidalis keloidalis #4
    keloid folliculitis #6
    congenital port #6
    stromal retraction #7
    pleomorphic basal #7
    chronic scarring folliculitis #7
    hair follicle absence #7
    acquired portwine stains #7
    histologic findings response #7
    scarring folliculitis #10
    buschke‐ollendorff syndrome #10
    tire syndrome #10
    pin egfr #10
    dna ploidy diagnosis #10
    manifestations atelosteogenesis #11
    bccs studied #12
    firm plaques #13
    absence sebaceous glands #13
    keloidalis #14
    michelin tire syndrome #16
    michelin tire #19
    19 pleomorphic #20
    dirofilaria tenuis #20
    bcc studied #21
    nodules examination #21
    osmolar agents #22
    acquired port #23
    acquired portwine stain #28

    Key People For Dna Ploidy

    Top KOLs in the world
    David William Hedley
    pancreatic cancer flow cytometry tumor hypoxia
    Ian W Taylor
    cellular dna content flow cytometry cell cycle
    Michael Leonard Friedlander
    ovarian cancer maintenance olaparib brca1 genes
    Elizabeth A Musgrove
    breast cancer cyclin d1 cell cycle
    Catherine A Rugg
    transferrin receptor expression cellular dna content flow cytometry
    Bernhard Tribukait
    cell cycle flow cytometry ulcerative colitis

    Arlene J Herzberg:Expert Impact

    Concepts for whichArlene J Herzberghas direct influence:Dna ploidy,  Acne keloidalis,  Basal cell,  Basal cell carcinoma,  Granuloma faciale,  Endocardial fibroelastosis,  Image cytometry,  Michelin tire syndrome.

    Arlene J Herzberg:KOL impact

    Concepts related to the work of other authors for whichfor which Arlene J Herzberg has influence:Acne keloidalis,  Adenoid cystic carcinoma,  Granuloma faciale,  Contrast media,  Lymphatic vessels,  Progesterone dermatitis,  Primary leiomyoma.



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    Department of Pathology and Laboratory Medicine, East Carolina University School of Medicine, Greenville, NC | Department of Pathology (A.J.H.), Peninsula Regional Medical Center, Salisbury, Maryland; Department of Pathology (P.R.B.), Naples Communit