Robert-Jan van Oostenbrugge

Robert-Jan van Oostenbrugge

Erasmus Mc University Medical Center, Rotterdam, Maastricht University Medical Center, Maastricht, Academic Medical Center, Amsterdam, And, Leiden University Medical Center, ...

Direct Impact

Concepts for which Robert-Jan van Oostenbrugge has direct influence:

acute ischemic stroke
endovascular thrombectomy
cerebral small vessel
cognitive impairment
collateral status
odds ratio
modified rankin

External impact

Concepts related to the work of other authors for which Robert-Jan van Oostenbrugge has influence:

collateral status
acute ischemic stroke
stent retriever
clean trial
imaging determinants
odds ratio
intracerebral hemorrhage

Prominent publications by Robert-Jan van Oostenbrugge

KOL-Index: 163 BACKGROUND: Intra-arterial treatment in acute ischemic stroke is safe and effective as recently shown in several randomized clinical trials. The level of experience of the interventionist performing the IAT procedure has not been studied. The present study investigates effects of interventionists' experience on technical aspects of the procedure and clinical outcome of the patient. METHODS: ...
Known for
Functional Observed | Selection Strict | Proximal Intracranial | Recanalization Neurological
KOL-Index: 146 BACKGROUND: Mechanical thrombectomy with stent retrievers has proved to be safe and effective in endovascular treatment of acute ischemic stroke. Direct aspiration has shown revascularization rates comparable to those of stent retrievers in the recent ASTER and COMPASS trials. However, the efficacy of aspiration in routine clinical practice has not yet been shown. OBJECTIVE: To show that ...
Known for
Multicenter Real-Life | 70 Min | Aster Compass Trials | Vessel Occlusion
KOL-Index: 136 BACKGROUND AND PURPOSE: Thrombectomy with stent retriever and direct aspiration are equally effective in the endovascular treatment of anterior circulation acute ischemic stroke. We report efficacy and safety of initial treatment technique per occlusion segment. METHODS: For this study, we analyzed data from the MR CLEAN Registry, a prospective, observational study in all centers that ...
Known for
Minutes | Intracranial | Endovascular | 73
KOL-Index: 135 BACKGROUND AND PURPOSE: Whereas a clear benefit of endovascular treatment for anterior circulation stroke has been established, randomized trials assessing the posterior circulation have failed to show efficacy. Previous studies in anterior circulation stroke suggest that advanced thrombectomy devices were of great importance in achieving clinical benefit. Little is known about the effect of ...
Known for
Aspects | Acute Ischemic Stroke | Netherlands | December
KOL-Index: 132 Intra-arterial therapy (IAT) for ischemic stroke aims to save brain tissue. Collaterals are thought to contribute to prolonged penumbra sustenance. In this study, we investigate the effect of collateral status on brain tissue salvage with IAT. In 500 patients randomized between IAT and standard care, collateral status was graded from 0 (absent) to 3 (good). Final infarct volumes (FIV) were ...
Known for
Brain Tissue Salvage | Higher Collateral Grades | Status Tissue | Post-Treatment
KOL-Index: 131 BACKGROUND AND PURPOSE: Acute ischemic stroke due to large vessel occlusion is uncommon in young adults. We assessed stroke cause in young patients and compared their outcomes after endovascular thrombectomy with older patients. METHODS: We used data (March 2014 until November 2017) of patients with an anterior circulation large vessel occlusion stroke from the MR CLEAN (Multicenter ...
Known for
Symptomatic Intracranial | 18-49 | Endovascular Acute | 310 10
KOL-Index: 69 BACKGROUND: Endovascular treatment (EVT) with or without intravenous thrombolysis (IVT) is effective and safe in is-chemic stroke caused by large vessel occlusion, but IVT might delay time to EVT or increase risk of intracranial hemorrhage (ICH). We assessed the influence of prior IVT on time to treatment and risk of ICH in patients treated with EVT. METHODS: We analyzed data from the MR ...
Known for
Ivt Prior | Clean Registry | Chemic | Groin Times
KOL-Index: 62 OBJECTIVE: To investigate the association between white matter lesions (WML) and functional outcome in patients with acute ischemic stroke (AIS) and the modification of the effect of endovascular treatment (EVT) by WML. METHODS: We used data from the Multicenter Randomized Clinical Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands (MR CLEAN) trial and assessed ...
Known for
Acor | Interaction Term | Functional Ais | Baseline Noncontrast Imaging
KOL-Index: 60 Introduction: Many consequences of cerebrovascular disease are identifiable by magnetic resonance imaging (MRI), but variation in methods limits multicenter studies and pooling of data. The European Union Joint Program on Neurodegenerative Diseases (EU JPND) funded the HARmoNizing Brain Imaging MEthodS for VaScular Contributions to Neurodegeneration (HARNESS) initiative, with a focus on ...
Known for
Deidentified Mri Repository | Surveys | Neurodegenerative | Current Mri Biomarkers
KOL-Index: 55 BackgroundEndovascular treatment (EVT) has greatly improved the prognosis of acute ischemic stroke (AIS) patients with a proximal intracranial large vessel occlusion (LVO) of the anterior circulation. Currently, there is clinical equipoise concerning the added benefit of intravenous alteplase administration (IVT) prior to EVT. The aim of this study is to assess the efficacy and safety of ...
Known for
Modified Rankin | Inferiority | 11 Ratio | Backgroundendovascular

Erasmus MC University Medical Center, Rotterdam, Maastricht University Medical Center, Maastricht, Academic Medical Center, Amsterdam, and, Leiden University Medical Center, Leiden, The Netherlands

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