Robin Lemmens: Influence Statistics

Robin Lemmens

Robin Lemmens

Department of Neurology, University Hospitals Leuven, Leuven, Belgium | Department of Neuroscience, Katholieke Universiteit Leuven, Campus Gasthuisberg O&N2; Leuven (BE-3000), ...

Robin Lemmens: Expert Impact

Concepts for which Robin Lemmens has direct influence: Ischaemic stroke , Intravenous alteplase , Ischemic stroke , Cerebral microbleeds , Functional outcome , Stroke patients , Transient ischemic attack .

Robin Lemmens: KOL impact

Concepts related to the work of other authors for which for which Robin Lemmens has influence: Ischemic stroke , Cerebral microbleeds , Amyotrophic lateral sclerosis , Atrial fibrillation , Bempedoic acid , Intravenous thrombolysis , Cerebrovascular disease .

KOL Resume for Robin Lemmens

Year
2022

Department of Neurology, University Hospitals Leuven, Leuven, Belgium

2021

Department of Neurosciences, Experimental Neurology, KU Leuven–University of Leuven; VIB Center for Brain & Disease Research; Department of Neurology, University Hospitals Leuven, Leuven, Belgium

2020

Department of Neuroscience, Katholieke Universiteit Leuven, Campus Gasthuisberg O&N2; Herestraat 49 box 1021; Leuven (BE-3000), Belgium

2019

Experimental Neurology and Leuven Institute for Neuroscience and Disease, Katholieke Universiteit Leuven, University of Leuven, Laboratory of Neurobiology, Leuven, Belgium

Department of Neurology, University Hospitals Leuven (R.L.).

2018

Dept of Neurosciences, Experimental Neurology and Leuven Rsch Institute for Neuroscience a, KU - Univ of Leuven, Leuven, Belgium

University Hospitals Leuven. Netherlands

2017

From Department of Neurology, University of California, San Francisco (J.D.E.); AstraZeneca, Gothenburg, Sweden (M.A., S.B.-S., H.D., P.H., M.J., J.J.); Stanford University Medical Center, Stanford Stroke Center, Palo Alto, CA (G.W.A.); Department of Neurology and Stroke Center, Bichat University Hospital and Medical School, Paris, France (P.A.); Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA (S.R.E.); National Cerebral and Cardiovascular Center, Suita, Osaka, Japan (K.M.); Stroke Unit, Hospital Vall d’Hebron, Barcelona, Spain (C.A.M.); Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, China (Y.W.); Department of Medicine and Therapeutics, Chinese University of Hong Kong, China (K.S.L.W.); and Dean’s Office, Dell Medical School, University of Texas, Austin (S.C.J.).

Stanford University, Stanford, CA, USA

2008

Service of Neurology (University Hospital Leuven) and Laboratory for Neurobiology, Section of Experimental Neurology, University of Leuven, Leuven B-3000, Belgium

Prominent publications by Robin Lemmens

KOL-Index: 18820 . BACKGROUND: Patients with minor acute ischemic stroke or transient ischemic attack are at high risk for subsequent stroke, and more potent antiplatelet therapy in the acute setting is needed. However, the potential benefit of more intense antiplatelet therapy must be assessed in relation to the risk for major bleeding. The SOCRATES trial (Acute Stroke or Transient Ischemic Attack Treated ...
Known for Transient Ischemic Attack | Acute Stroke | Ticagrelor Aspirin | Major Bleeding
KOL-Index: 18776 . BACKGROUND: Cerebral microbleeds are a neuroimaging biomarker of stroke risk. A crucial clinical question is whether cerebral microbleeds indicate patients with recent ischaemic stroke or transient ischaemic attack in whom the rate of future intracranial haemorrhage is likely to exceed that of recurrent ischaemic stroke when treated with antithrombotic drugs. We therefore aimed to ...
Known for Ischaemic Stroke | Cerebral Microbleeds | Intracranial Haemorrhage | Pooled Analysis
KOL-Index: 13555 . BACKGROUND AND PURPOSE: Among patients with a transient ischemic attack or minor ischemic strokes, those with ipsilateral atherosclerotic stenosis of cervicocranial vasculature have the highest risk of recurrent vascular events. METHODS: In the double-blind THALES (The Acute Stroke or Transient Ischemic Attack Treated With Ticagrelor and ASA for Prevention of Stroke and Death) trial, we ...
Known for Ischemic Stroke | Ticagrelor Aspirin | Hazard Ratio | Attack Transient
KOL-Index: 12537 . BACKGROUND: The value of administering intravenous alteplase before endovascular treatment (EVT) for acute ischemic stroke has not been studied extensively, particularly in non-Asian populations. METHODS: We performed an open-label, multicenter, randomized trial in Europe involving patients with stroke who presented directly to a hospital that was capable of providing EVT and who were ...
Known for Intravenous Alteplase | Endovascular Treatment | Evt Patients | Modified Rankin Scale
KOL-Index: 8822 . BACKGROUND: Patients who have had a stroke with unknown time of onset have been previously excluded from thrombolysis. We aimed to establish whether intravenous alteplase is safe and effective in such patients when salvageable tissue has been identified with imaging biomarkers. METHODS: We did a systematic review and meta-analysis of individual patient data for trials published before Sept ...
Known for Intravenous Alteplase | Patients Stroke | Functional Outcome | Time Onset
KOL-Index: 7856 . AIMS: To provide contemporary data on the implementation of European guideline recommendations for lipid-lowering therapies (LLTs) across different settings and populations and how this impacts low-density lipoprotein cholesterol (LDL-C) goal achievement. METHODS AND RESULTS: An 18 country, cross-sectional, observational study of patients prescribed LLT for primary or secondary prevention ...
Known for Secondary Primary | Patients Llt | Sectional Observational | Vinci Study
KOL-Index: 7766 . OBJECTIVES: To assess the association between cerebral microbleeds (CMBs) and future spontaneous intracerebral hemorrhage (ICH) risk in ischemic stroke patients with nonvalvular atrial fibrillation (AF) taking oral anticoagulants. METHODS: This was a meta-analysis of cohort studies with >50 patients with recent ischemic stroke and documented AF, brain MRI at baseline, long-term oral ...
Known for Hemorrhage Risk | Presence Cmb | Brain Microbleeds | Ischemic Stroke
KOL-Index: 7603 . OBJECTIVE: For 3,670 stroke patients from the United Kingdom, United States, Australia, Belgium, and Italy, we performed a genome-wide meta-analysis of white matter hyperintensity volumes (WMHV) on data imputed to the 1000 Genomes reference dataset to provide insights into disease mechanisms. METHODS: We first sought to identify genetic associations with white matter hyperintensities in a ...
Known for White Matter | Stroke Patients | Genetic Associations | Genome Wide
KOL-Index: 6890 . OBJECTIVE: To measure the global impact of COVID-19 pandemic on volumes of IV thrombolysis (IVT), IVT transfers, and stroke hospitalizations over 4 months at the height of the pandemic (March 1 to June 30, 2020) compared with 2 control 4-month periods. METHODS: We conducted a cross-sectional, observational, retrospective study across 6 continents, 70 countries, and 457 stroke centers. ...
Known for Global Impact | Covid19 Stroke | 6 Continents | 70 Countries
KOL-Index: 6266 . Amyotrophic lateral sclerosis (ALS) is a spontaneous, relentlessly progressive motor neuron disease, usually resulting in death from respiratory failure within 3 years. Variation in the genes SOD1 and TARDBP accounts for a small percentage of cases, and other genes have shown association in both candidate gene and genome-wide studies, but the genetic causes remain largely unknown. We have ...
Known for Elongator Protein | Neuron Degeneration | Elp3 Gene | Male Mice Mice
KOL-Index: 6213 . BACKGROUND: S44819, a selective GABAA α5 receptor antagonist, reduces tonic post-ischaemic inhibition of the peri-infarct cortex. S44819 improved stroke recovery in rodents and increased cortical excitability in a transcranial magnetic stimulation study in healthy volunteers. The Randomized Efficacy and Safety Trial of Oral GABAA α5 antagonist S44819 after Recent ischemic Event (RESTORE ...
Known for Stroke Treatment | Antagonist S44819 | Gabaa Α5 | Tonic Inhibition
KOL-Index: 5835 . RATIONALE: Ischemic stroke is among the leading causes of adult disability. Part of the variability in functional outcome after stroke has been attributed to genetic factors but no locus has been consistently associated with stroke outcome. OBJECTIVE: Our aim was to identify genetic loci influencing the recovery process using accurate phenotyping to produce the largest GWAS (genome-wide ...
Known for Functional Outcome | Ischemic Stroke | Genetic Factors | Genome Wide
KOL-Index: 5547 . OBJECTIVE: To examine etiologic stroke subtypes and vascular risk factor profiles and their association with white matter hyperintensity (WMH) burden in patients hospitalized for acute ischemic stroke (AIS). METHODS: For the MRI Genetics Interface Exploration (MRI-GENIE) study, we systematically assembled brain imaging and phenotypic data for 3,301 patients with AIS. All cases underwent ...
Known for Ischemic Stroke | White Matter | Hyperintensity Burden | Diabetes Mellitus
KOL-Index: 5451 . OBJECTIVE: To discover common genetic variants associated with poststroke outcomes using a genome-wide association (GWA) study. METHODS: The study comprised 6,165 patients with ischemic stroke from 12 studies in Europe, the United States, and Australia included in the GISCOME (Genetics of Ischaemic Stroke Functional Outcome) network. The primary outcome was modified Rankin Scale score ...
Known for Functional Outcome | Ischemic Stroke | Genome Wide | Genetic Variant
KOL-Index: 4534 . BACKGROUND: Within randomized clinical trials (RCTs), coiling of the ruptured aneurysm to prevent rebleeding results in better outcomes than clipping in patients with aneurysmal subarachnoid hemorrhage (aSAH). OBJECTIVE: To study the association of coiling and clipping with outcome after aSAH in daily clinical practice. METHODS: In this controlled, nonrandomized study, we compared outcomes ...
Known for Subarachnoid Hemorrhage | Clipping Coiling | Aneurysm Ruptured | Endovascular Procedures

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Department of Neurology, University Hospitals Leuven, Leuven, Belgium | Department of Neuroscience, Katholieke Universiteit Leuven, Campus Gasthuisberg O&N2; Leuven (BE-3000), Belgium. | KU Leuven - Department of Neurosciences, Leuven 3000, Belgium |