David Araújo-Vilar

David Araújo-Vilar

Universidad De Santiago De Compostela, University Of Santiago De Compostela, Cimus, Idis, Spain, Uetem – Molecular Pathology Group. Idis-Cimus, University Of Santiago De ...

Direct Impact

Concepts for which David Araújo-Vilar has direct influence:

adipose tissue
insulin resistance
lmna gene
minimal model
glucose effectiveness
mutant seipin
familial lipodystrophy

External impact

Concepts related to the work of other authors for which David Araújo-Vilar has influence:

adipose tissue
insulin resistance
lipodystrophy syndrome
pima indians
lmna gene
mutant seipin
adipocyte differentiation

Prominent publications by David Araújo-Vilar

KOL-Index: 93 Lipodystrophies are a heterogeneous group of rare conditions characterised by the loss of adipose tissue. The most common forms are the familial partial lipodystrophy (FPLD) syndromes, which include a set of disorders, usually autosomal dominant, due to different pathogenetic mechanisms leading to improper fat distribution (loss of fat in the limbs and gluteal region and variable regional ...
Known for
Lipodystrophy Fpld | Fat Accumulation | Metabolic Complications | Diagnostic Approaches
KOL-Index: 82 BackgroundC3 hypocomplementemia and the presence of C3 nephritic factor (C3NeF), an autoantibody causing complement system over-activation, are common features among most patients affected by Barraquer-Simons syndrome (BSS), an acquired form of partial lipodystrophy. Moreover, BSS is frequently associated with autoimmune diseases. However, the relationship between complement system ...
Known for
Backgroundc3 Hypocomplementemia | Complement Over-Activation | Autoantibody Anti | Central Pathological Event
KOL-Index: 61 Seipin, encoded by the BSCL2 gene, is a protein that in humans is expressed mainly in the central nervous system. Uniquely, certain variants in BSCL2 can cause both generalized congenital lipodystrophy type 2, upper and/or lower motor neuron diseases, or progressive encephalopathy, with a poor prognosis during childhood. The latter, Celia's encephalopathy, which may or may not be associated ...
Known for
Progressive Encephalopathy
KOL-Index: 40 BackgroundLipodystrophy syndromes comprise a group of extremely rare and heterogeneous diseases characterized by a selective loss of adipose tissue in the absence of nutritional deprivation or catabolic state. Because of the rarity of each lipodystrophy subform, research in this area is difficult and international co-operation mandatory. Therefore, in 2016, the European Consortium of ...
Known for
Eclip

Lipodystrophy


[ PUBLICATION ]
KOL-Index: 38 Lipodystrophy is a clinical entity characterized by an abnormal distribution of adipose tissue, including lipoatrophy. It is typically, but not always, associated with insulin resistance and other metabolic alterations. Lipodystrophies have a genetic origin or are acquired in response pathogenic insults, which have not been well-characterized. In generalized lipodystrophy, adipose tissue is ...
Known for
Lipodystrophy Lipoatrophy
KOL-Index: 36 A variety of missense mutations in LMNA (the gene for lamin C and prelamin A) cause familial partial lipodystrophy (FPLD), a disease associated with reduced adipose tissue, particularly in the limbs. Several studies have reported that fibroblasts from FPLD subjects have an accumulation of prelamin A. Those findings were intriguing but also perplexing because many of the LMNA missense ...
Known for
Lmna Lipodystrophy | Mutant Fibroblasts | Farnesylation | Mutations Causing
KOL-Index: 36 PurposeThe purpose of this study is to summarize the effectiveness and safety of metreleptin in patients with congenital or acquired generalized lipodystrophy.MethodsPatients (n = 66) aged ≥6 months had lipodystrophy, low circulating leptin, and ≥1 metabolic abnormality (diabetes mellitus, insulin resistance, or hypertriglyceridemia). Metreleptin dose (once or twice daily) was titrated to a ...
Known for
Hba1c ≥30 Decrease | Glycated Hemoglobin | ≥1 | Tgs Medications
KOL-Index: 35 The nuclear lamina is a complex reticular structure that covers the inner face of the nucleus membrane in metazoan cells. It is mainly formed by intermediate filaments called lamins, and exerts essential functions to maintain the cellular viability. Lamin A/C provides mechanical steadiness to the nucleus and regulates genetic machinery. Laminopathies are tissue-specific or systemic disorders ...
Known for
Intermediate Filaments | Laminopathies Disorders | Premature Aging Syndromes | 2 Familial Lipodystrophy
KOL-Index: 31
Known for
Lipodistróficos Infrecuentes
KOL-Index: 31 OBJECTIVE: Lipodystrophy syndromes are extremely rare disorders of deficient body fat associated with potentially serious metabolic complications, including diabetes, hypertriglyceridemia, and steatohepatitis. Due to their rarity, most clinicians are not familiar with their diagnosis and management. This practice guideline summarizes the diagnosis and management of lipodystrophy syndromes ...
Known for
Committee Meetings | Societies Reviewed

Universidad de Santiago de Compostela, University of Santiago de Compostela, CIMUS, IDIS, Spain, UETeM – Molecular Pathology Group. IDIS-CIMUS, University of Santiago de Compostela, Spain University Clinical Hospital of Santiago de Compostela, Divisi

https://www.g2.com/products/key-opinion-leaders-kols/reviews https://www.bbb.org/us/fl/doral/profile/data-analytics/key-opinion-leaders-0633-92023858 https://www.trustpilot.com/review/keyopinionleaders.com https://www.yelp.com/biz/key-opinion-leaders-miami


© 2022 - Key Opinion Leaders -
Key Opinion Leaders, LLC ,
2025 NW 102 Avenue, Suite 111 Doral , FL   33172