• Alcohol Dependence
    • Florian Naudet
    • Florian Naudet: Influence Statistics

      Florian Naudet

      Florian Naudet

      Univ Rennes, CHU Rennes, Inserm, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, F-35000, Rennes, France | Université de Rennes 1 - CHU Rennes, ...

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      Florian Naudet:Expert Impact

      Concepts for whichFlorian Naudethas direct influence:Alcohol dependence,Randomized controlled trials,Data sharing,Observational studies,Periodontal regeneration,Transparency promotion,Surgical journals,Biomedical journals.

      Florian Naudet:KOL impact

      Concepts related to the work of other authors for whichfor which Florian Naudet has influence:Data sharing,Deep brain stimulation,Observational studies,Major depressive disorder,Nucleus accumbens,Alcohol dependence,Central nervous.

      KOL Resume for Florian Naudet


      Univ Rennes, CHU Rennes, Inserm, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, F-35000, Rennes, France


      Univ Rennes, CHU Rennes, Inserm, CIC 1414 (Centre d’Investigation Clinique de Rennes), F-35000 Rennes, France

      affiliation not provided to SSRN


      University of Rennes, CHU Rennes, Inserm, CIC 1414 [(Centre d'Investigation Clinique de Rennes)], F‐ 35000, Rennes, France


      CHU Rennes, Inserm, CIC 1414 [(Centre d’Investigation Clinique de Rennes)], Univ Rennes, Rennes, France

      Meta-Research Innovation Center at Stanford (METRICS), Stanford University, Stanford, CA, USA

      Meta‐research Innovation Center (METRICS), Stanford University, Palo Alto, California


      Centre Hospitalier Universitaire de Rennes, Rennes, France

      Meta-Research Innovation Center at Stanford (METRICS), Stanford University, Stanford, California, United States of America

      Department of Medicine, Stanford University School of Medicine, Stanford, USA


      INSERM Centre d’Investigation Clinique 1414, Centre Hospitalier Universitaire de Rennes, Rennes, France

      Meta-Research Innovation Center at Stanford (METRICS), Stanford University, Palo Alto, CA, USA


      INSERM U669, Paris, France

      Stanford University, Meta-Research Innovation Center at Stanford (METRICS), Stanford, 59479 California, États-Unis


      Clinical Investigation Center, INSERM 0203, Rennes University Hospital, University of Rennes 1, Rennes, France

      Sample of concepts for which Florian Naudet is among the top experts in the world.
      Concept World rank
      transparency promotion #1

      Prominent publications by Florian Naudet

      KOL-Index: 12448

      BACKGROUND AND AIMS: Pharmacologically controlled drinking in the treatment of alcohol dependence or alcohol use disorders (AUDs) is an emerging concept. Our objective was to explore the comparative effectiveness of drugs used in this indication.

      DESIGN: Systematic review with direct and network meta-analysis of double-blind randomized controlled trials (RCTs) assessing the efficacy of nalmefene, naltrexone, acamprosate, baclofen or topiramate in non-abstinent adults diagnosed with ...

      Known for Alcohol Dependence | Nalmefene Naltrexone | Controlled Drinking | Health Outcomes | Topiramate Treatment
      KOL-Index: 10722

      BACKGROUND: To compare response to antidepressants between randomized controlled trials (RCTs) and observational trials.

      METHODS AND FINDINGS: Published and unpublished studies (from 1989 to 2009) were searched for by 2 reviewers on Medline, the Cochrane library, Embase, clinicaltrials.gov, Current Controlled Trial, bibliographies and by mailing key organisations and researchers. RCTs and observational studies on fluoxetine or venlafaxine in first-line treatment for major depressive ...

      Known for Observational Studies | Randomized Controlled Trials | Major Depressive Disorder | Rcts Treatment | Study Characteristics
      KOL-Index: 10105

      BACKGROUND: Treatment of relapsed/refractory (R/R) primary CNS lymphoma (PCNSL) is poorly defined, because randomized trials and large studies are lacking. The aim of this study was to analyze the characteristics, management, and outcome of R/R PCNSL patients after first-line therapy in a nationwide cohort.

      METHODS: We analyzed R/R PCNSL patients following first-line treatment who had been prospectively registered in the database of the French network for oculocerebral lymphoma (LOC) ...

      Known for Primary Cns Lymphoma | Pcnsl Patients | Salvage Therapy | Loc Network | Relapsed Refractory
      KOL-Index: 9674

      BACKGROUND: Nalmefene is a recent option in alcohol dependence treatment. Its approval was controversial. We conducted a systematic review and meta-analysis of the aggregated data (registered as PROSPERO 2014:CRD42014014853) to compare the harm/benefit of nalmefene versus placebo or active comparator in this indication.

      METHODS AND FINDINGS: Three reviewers searched for published and unpublished studies in Medline, the Cochrane Library, Embase, ClinicalTrials.gov, Current Controlled ...

      Known for Alcohol Dependence | Nalmefene Placebo | Randomized Controlled Trials | Sensitivity Analyses | Consumption Outcomes
      KOL-Index: 9542

      OBJECTIVES: To explore the effectiveness of data sharing by randomized controlled trials (RCTs) in journals with a full data sharing policy and to describe potential difficulties encountered in the process of performing reanalyses of the primary outcomes.

      DESIGN: Survey of published RCTs.

      SETTING: PubMed/Medline.

      ELIGIBILITY CRITERIA: RCTs that had been submitted and published by The BMJ and PLOS Medicine subsequent to the adoption of data sharing policies by these journals.

      MAIN OUTCOME ...

      Known for Data Sharing | Randomized Controlled Trials | Primary Outcomes | Rcts Journals | Eligibility Criteria
      KOL-Index: 9311

      OBJECTIVE: To evaluate the potential efficacy of mesenchymal stem cells (MSCs) in periodontal regeneration in humans on the following main outcomes: clinical attachment level (CAL), probing depth (PD), and gingival recession (GR).

      BACKGROUND: The clinical application of stem cells in periodontal regeneration has begun in recent years, but clinical practices are not yet standardized and no recommendations are available at this time.

      METHODS: Electronic database searches and hand searches ...

      Known for Periodontal Regeneration | Mesenchymal Stem Cells | Randomized Controlled | Attachment Loss | Gingival Recession
      KOL-Index: 8059

      OBJECTIVE: To evaluate the association between gifts from pharmaceutical companies to French general practitioners (GPs) and their drug prescribing patterns.

      DESIGN: Retrospective study using data from two French databases (National Health Data System, managed by the French National Health Insurance system, and Transparency in Healthcare).

      SETTING: Primary care, France.

      PARTICIPANTS: 41 257 GPs who in 2016 worked exclusively in the private sector and had at least five registered ...

      Known for Pharmaceutical Companies | Outcome Measures | Drug Prescribing | Transparency Healthcare | General Practitioners
      KOL-Index: 8016

      BACKGROUND: One of the main selection criteria of the quality of a liver graft is the degree of steatosis, which will determine the success of the transplantation. The aim of this study was to evaluate the ability of FibroScan and its related methods Controlled Attenuation Parameter and Liver Stiffness to assess objectively steatosis and fibrosis in livers from brain-dead donors to be potentially used for transplantation.

      METHODS: Over a period of 10 months, 23 consecutive brain dead ...

      Known for Liver Stiffness | Controlled Attenuation Parameter | Steatosis Assessment | Dead Donors | Gold Standard
      KOL-Index: 7905

      This pilot study was designed to assess the efficacy of low-frequency repetitive transcranial magnetic stimulation (rTMS) over the right orbitofrontal cortex (OFC) by means of a double-cone coil in patients suffering from obsessive-compulsive disorder. We hypothesized that low-frequency stimulation of the OFC would lead to a reduction in clinical symptoms, as measured on the Yale-Brown Obsessive Compulsive Scale (Y-BOCS). A randomized, double-blind, crossover design was implemented with ...

      Known for Orbitofrontal Cortex | Compulsive Disorder | Magnetic Stimulation | Repetitive Transcranial | Ybocs Scores
      KOL-Index: 6552

      OBJECTIVE: This review aimed to investigate the therapeutic potential of Deep Brain Stimulation (DBS) for treating resistant Major Depressive Disorder (MDD). We explored the role of Nucleus accumbens (Nac) as a target for treatment.

      METHOD: We made a systematic review of all studies examining the mechanisms of action of high frequency brain stimulation and the pathophysiology of MDD. We also reported all the studies exploring the therapeutic potential of DBS in MDD.

      RESULTS: As a central ...

      Known for Deep Brain Stimulation | Nucleus Accumbens | Nac Dbs | Depressive Disorder | Depressed Patients
      KOL-Index: 6361

      Androgen deprivation therapy (ADT) is a cornerstone therapy for advanced prostate cancer (PCa). We hypothesized that cardiovascular (CV) risk is different across the various ADT modalities to compare their effects on CV morbidity and mortality, and all-cause mortality in patients with PCa. To investigate more in depth potential CV risk heterogeneity focusing on coronary (main outcome) and cerebrovascular risk, CV, and overall mortality. We performed a Medline and Embase query, without ...

      Known for Cardiovascular Risk | Observational Studies | Androgen Deprivation Therapy | Randomized Controlled Trials | Prostate Cancer
      KOL-Index: 6150

      Assessment of researchers is necessary for decisions of hiring, promotion, and tenure. A burgeoning number of scientific leaders believe the current system of faculty incentives and rewards is misaligned with the needs of society and disconnected from the evidence about the causes of the reproducibility crisis and suboptimal quality of the scientific publication record. To address this issue, particularly for the clinical and life sciences, we convened a 22-member expert panel workshop ...

      Known for Promotion Tenure | Reproducibility Crisis | Assessing Scientists | Faculty Humans | Current Incentive
      KOL-Index: 6129

      High-frequency deep brain stimulation (DBS) represents a major stake for treatment for treatment-resistant depression (TRD). We describe a preliminary trial of DBS of two potential brain targets in chronic TRD: the nucleus accumbens (Acb) and, in the event of failure, the caudate nucleus. Patients were followed for 6 months before surgery (M0). From M1 to M5, they underwent stimulation of the Acb target. PET scans allowed us to track metabolic modifications resulting from this ...

      Known for Brain Stimulation | Resistant Depression | Nucleus Accumbens | Emission Tomography | Cingulate Gyrus
      KOL-Index: 5882

      OBJECTIVE: To explore the implementation of the International Committee of Medical Journal Editors (ICMJE) data-sharing policy which came into force on 1 July 2018 by ICMJE-member journals and by ICMJE-affiliated journals declaring they follow the ICMJE recommendations.

      DESIGN: A cross-sectional survey of data-sharing policies in 2018 on journal websites and in data-sharing statements in randomised controlled trials (RCTs).

      SETTING: ICMJE website; PubMed/Medline.


      Known for Data Sharing | Biomedical Journals | Rcts Published | Journal Policies | International Committee
      KOL-Index: 5639

      We aimed to review and discuss the evidence-based arguments for the efficacy of electroconvulsive therapy (ECT) in the treatment of catatonia. Randomized controlled trials (RCTs) and observational studies focusing on the response to ECT in catatonia were selected in PubMed, the Cochrane Library, Embase, ClinicalTrials.gov and Current Controlled Trials through October 2016 and qualitatively described. Trials assessing pre-post differences using a catatonia or clinical improvement rating ...

      Known for Electroconvulsive Therapy | Ect Catatonia | Catatonic Symptoms | Rating Scale

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      Univ Rennes, CHU Rennes, Inserm, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, F-35000, Rennes, France | Université de Rennes 1 - CHU Rennes, Inserm, Irset [(Institut de recherche en santé, environnement et travail)]

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