• Disease
  • Allergic
  • Allergic Rhinitis
  • Eli O Meltzer

    Prominent publications by Eli O Meltzer

    KOL Index score: 19140

    BACKGROUND: Cetirizine, a new once-daily highly specific H1-antagonist, has been shown in conventional studies to be efficacious in the treatment of seasonal and perennial allergic rhinitis and chronic idiopathic urticaria.

    OBJECTIVE: The efficacy, duration and onset of action, and safety of cetirizine, 10 mg once daily, was compared with that of loratadine, 10 mg once daily, and placebo in a field study of patients with seasonal allergic rhinitis.

    METHODS: This was a randomized, ...

    Also Ranks for: Seasonal Allergic Rhinitis |  cetirizine loratadine |  placebo period |  onset action |  illness time factors
    KOL Index score: 19021

    BACKGROUND: In patients with severe asthma, tiotropium improves lung function and exacerbation risk when added to high-dose inhaled corticosteroids plus long-acting β2 agonists. We aimed to assess the safety and efficacy of tiotropium in patients with moderate asthma who were symptomatic despite treatment with medium-dose inhaled corticosteroids.

    METHODS: We did two 24-week, replicate, randomised, double-blind, placebo-controlled, parallel-group, active-comparator trials at 233 sites in ...

    Also Ranks for: Inhaled Corticosteroids |  tiotropium patients |  symptomatic asthma |  μg placebo |  randomised trials
    KOL Index score: 18589

    BACKGROUND: In fall 2004, the first Azelastine Cetirizine Trial demonstrated statistically significant improvements in the total nasal symptom score (TNSS) and Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ) scores with the use of azelastine nasal spray vs oral cetirizine in patients with seasonal allergic rhinitis (SAR).

    OBJECTIVE: To compare the effects of azelastine nasal spray vs cetirizine on the TNSS and RQLQ scores in patients with SAR.

    METHODS: This 2-week, double-blind, ...

    Also Ranks for: Azelastine Nasal Spray |  seasonal allergic rhinitis |  intranasal administration |  patients sar |  nasal congestion
    KOL Index score: 16042

    BACKGROUND: Fexofenadine HCl (Allegra, Telfast) is approved in the US for twice-daily dosing for treatment of seasonal allergic rhinitis.

    OBJECTIVE: To determine the effect of once-daily fexofenadine HCl on patient-reported quality of life and impairment at work, in the classroom, and in daily activities due to seasonal allergic rhinitis symptoms.

    METHODS: This placebo-controlled, double-blind, randomized study included patients aged 12 to 65 years with moderate-to-severe seasonal ...

    Also Ranks for: Fexofenadine Hcl |  seasonal allergic |  activity impairment |  daily activities |  work classroom
    KOL Index score: 15664

    Many patients with allergic rhinitis (AR) have uncontrolled symptoms despite available treatment options. This study was designed to evaluate the efficacy and safety of MP29-02 (a novel intranasal formulation of fluticasone propionate [FP] and azelastine [AZ] hydrochloride), compared with monotherapy with FP, AZ, and placebo sprays for the treatment of seasonal allergic rhinitis (SAR). This 2-week randomized, double-blind, placebo-controlled trial was conducted in 779 patients with ...

    Also Ranks for: Fluticasone Propionate |  intranasal formulation |  seasonal allergic rhinitis |  azelastine hydrochloride |  efficacy safety
    KOL Index score: 15213

    Although the annual prevalence of physician-diagnosed hay fever has been previously reported, the prevalence of allergic rhinitis symptoms in the United States is uncertain. The purpose of this study was to estimate the prevalence of allergic rhinitis symptoms in the United States. A self-administered 10-item screening questionnaire regarding nasal symptoms was sent to representative households in the United States in January 2004. A total of 8,708 members (44.3%) reported nasal symptoms ...

    Also Ranks for: United States |  nasal symptoms |  perennial rhinitis |  america survey |  prevalence allergic
    KOL Index score: 14614

    Ipratropium bromide is an anticholinergic agent with topical activity that has been studied as a freon-propelled aerosol spray for therapy of nonallergic rhinitis. This is the first report of its use both as an aqueous nasal spray and in perennial allergic rhinitis. In this study 123 patients who had symptoms of perennial allergic rhinitis were randomized to receive ipratropium bromide 21 micrograms or 42 micrograms or placebo, one spray per nostril three times a day for 4 weeks. ...

    Also Ranks for: Ipratropium Bromide |  nasal spray |  perennial allergic |  42 micrograms |  severity rhinorrhea
    KOL Index score: 14338

    Seasonal allergic rhinitis (SAR) treatment should reduce symptoms and help patients resume normal function. This study was performed to determine the effect of olopatadine (Olo) nasal spray on symptoms, quality of life (QoL), work, and activities of SAR patients. A pooled analysis was conducted of two Institutional Review Board-approved, randomized, double-blind clinical trials that compared 2-week treatment with Olo 0.6% and Olo 0.4% to placebo. Symptoms were assessed with the Total ...

    Also Ranks for: Comprehensive Report |  quality life |  06 olo |  allergic rhinitis |  sar patients
    KOL Index score: 14254

    Rhinitis is a common chronic condition that has been shown in observational and interventional studies to have a substantial impact on the sufferer. This study was performed to describe the impact of symptoms of allergic rhinitis (AR) on sleep, quality of life, and productivity in a U.S. population. A cohort of AR sufferers and non-AR sufferers was assembled by screening a representative sample of 15,000 households with a self-administered questionnaire in January 2004. A subsample of ...

    Also Ranks for: United States |  quality life |  nasal symptoms |  perennial rhinitis |  seasonal sleep surveys
    KOL Index score: 14219

    BACKGROUND: A nasal spray containing the antiallergy agent olopatadine hydrochloride is being developed for the treatment of seasonal allergic rhinitis (SAR).

    OBJECTIVE: To evaluate the safety and efficacy of 2 concentrations of olopatadine nasal spray vs placebo in patients with SAR.

    METHODS: This was a multicenter, randomized, double-blind, placebo-controlled study. After a 3- to 21-day placebo run-in, 565 patients aged 12 to 80 years were randomized to receive 0.4% or 0.6% olopatadine ...

    Also Ranks for: Nasal Spray |  seasonal allergic rhinitis |  olopatadine hydrochloride |  patients sar |  04 06
    KOL Index score: 14103

    BACKGROUND: Comparative studies with topical corticosteroids and antihistamines for treatment of allergic rhinitis have not always demonstrated clear distinctions between the two on the basis of therapeutic efficacy.

    OBJECTIVE: This study was designed to compare the efficacy and tolerability of fluticasone propionate aqueous nasal spray with those of terfenadine in the treatment of seasonal allergic rhinitis.

    METHODS: Three hundred forty-eight patients with allergic rhinitis were given ...

    Also Ranks for: Fluticasone Propionate |  seasonal allergic rhinitis |  aqueous nasal spray |  4 weeks |  intranasal administration
    KOL Index score: 13583

    BACKGROUND: Product attributes influence patient preference for intranasal corticosteroid therapy in allergic rhinitis (AR).

    OBJECTIVE: The aim of the study was to compare the product sensory attributes and patient preferences of fluticasone furoate (FF) and fluticasone propionate (FP) nasal sprays in patients with symptomatic perennial and/or seasonal AR.

    METHODS: This randomized, multicenter, double-blind, single-dose, crossover study enrolled 127 patients with a diagnosis of AR as ...

    Also Ranks for: Allergic Rhinitis |  fluticasone furoate |  sensory attributes |  nasal spray |  crossover dosing
    KOL Index score: 13314

    BACKGROUND: The efficacy and safety of mometasone furoate aqueous nasal spray (MFNS; Nasonex) 200 microg once daily for the treatment and prophylaxis of seasonal allergic rhinitis (SAR) and treatment of perennial rhinitis have been demonstrated in adults. However, the dose response of MFNS in pediatric patients has not yet been characterized.

    OBJECTIVE: This study was conducted to determine the dose-response relationship of 3 different doses of MFNS in a pediatric population.

    METHODS: ...

    Also Ranks for: Seasonal Allergic Rhinitis |  mfns treatment |  mometasone furoate |  nasal spray |  4 weeks
    KOL Index score: 13282

    Quality of life, when referring to an individual's health, is called health-related quality of life (HRQL). HRQL focuses on patients' perceptions of their disease and measures impairments that have significant impact on the patient. Similar symptoms may vary in their effect on different individuals; the goal of therapy should be to reduce impairments that patients consider important. HRQL can be measured with generic or specific questionnaires. Specific questionnaires may be more ...

    Also Ranks for: Life Hrql |  allergic rhinitis |  specific questionnaires |  disease children |  agents anti


    Eli O Meltzer: Influence Statistics

    Sample of concepts for which Eli O Meltzer is among the top experts in the world.
    Concept World rank
    placebo individual nasal #1
    tablets symptoms #1
    1week screening period #1
    parents coached condition #1
    patient surveys treatments #1
    allergies united #1
    tnss intranasal fp #1
    aqueous budesonide #1
    difference cic80 bid #1
    rhinosinusitis initiative #1
    flareup sinusitis #1
    prior tss iss #1
    attributes fluticasone #1
    intranasal cromolyn #1
    rqlq questionnaires #1
    cpa clemastine #1
    mfns 100 #1
    maxillary sinusitis radiographs #1
    intranasal fp patients #1
    rhinitis olopatadine #1
    nasal congestion children #1
    concomitant asthma study #1
    groups 2 sprays #1
    illness cq7 #1
    rhinitis total #1
    rtnss 24hour #1
    cromolyn rhinitis symptoms #1
    activity classroom #1
    allergic rhinitis article #1
    tss prior tss #1
    signs 2 weeks #1
    patients flunisolide #1
    spray bdp #1
    receiving mf #1
    nonsedating humans fexofenadine #1
    allergic antiallergic agents #1
    relieving nasal #1
    scit sublingual allergy #1
    cic aze fp #1
    placebo hcl #1
    efficacy azelastine #1
    pehmr #1
    scent odor taste #1
    intranasal androstadienes #1
    rhinitis practice parameter #1
    15day study #1
    rhinitis onset #1
    basophilic cells neutrophils #1
    13item draft #1
    intranasal corticosteroids incss #1

    Key People For Allergic Rhinitis

    Top KOLs in the world
    JeanClaude Bousquet
    allergic rhinitis asthma control chronic respiratory diseases
    Giorgio Walter Canonica
    allergic rhinitis severe asthma sublingual immunotherapy
    Eli O Meltzer
    allergic rhinitis fluticasone propionate united states
    Paul B Van Cauwenberge
    allergic rhinitis nasal polyps chronic rhinosinusitis
    Claus Bachert
    nasal polyps chronic rhinosinusitis allergic rhinitis
    Alkis G Togias
    allergic rhinitis peanut allergy infectious diseases

    Eli O Meltzer:Expert Impact

    Concepts for whichEli O Meltzerhas direct influence:Allergic rhinitis,  Seasonal allergic rhinitis,  Fluticasone propionate,  Perennial rhinitis,  United states,  Nasal congestion,  Seasonal allergic,  Nasal spray.

    Eli O Meltzer:KOL impact

    Concepts related to the work of other authors for whichfor which Eli O Meltzer has influence:Allergic rhinitis,  Chronic rhinosinusitis,  Nasal polyps,  Fluticasone propionate,  Asthma control,  Quality life,  Inhaled corticosteroids.



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    Allergy Allergy and Asthma Medical Group and Research Center San Diego California USA. | Allergy and Asthma Medical Group and Research Center, University of California School of Medicine, San Diego, CA, USA. | Division of Allergy and Immunology, Depa