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    • JeanClaude Bousquet

      JeanClaude Bousquet

      Allergology and Immunology, Fraunhofer Institute for Translational Medicine and Pharmacology (ITMP), Berlin, Germany | Department of Dermatology and Allergy, Comprehensive ...



      KOL Resume for JeanClaude Bousquet


      Allergology and Immunology, Fraunhofer Institute for Translational Medicine and Pharmacology (ITMP), Berlin, Germany

      University Hospital and INSERM, Hopital Arnaud de Villeneuve, Montpellier, France

      Executive Board, EIP on AHA Reference Sites Collaborative Network, Brussels, Belgium


      Euforea, Brussels, Belgium.

      Charité, Universitätsmedizin Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Comprehensive Allergy Center, Department of Dermatology and Allergy, Berlin, Germany

      Allergology University Hospital Montpellier Montpellier France.

      Université Montpellier, France, Montpellier, France

      Charite Universitatsmedizin Berlin Campus Charite Mitte: Charite Universitatsmedizin Berlin



      JeanClaude Bousquet: Influence Statistics

      Sample of concepts for which JeanClaude Bousquet is among the top experts in the world.
      Concept World rank
      global asthma association #1
      glucoraphanin covid19 #1
      2019 aria #1
      languedocroussillon #1
      ige rast cap #1
      eaaci standards #1
      concept planetary health #1
      development new sensitizations #1
      current wheezing cw #1
      asthma endothelin #1
      asthma patients concomitant #1
      dispersed nasal #1
      aria achievements #1
      h1 blocker #1
      polysensitized monosensitized #1
      ait belgium #1
      paillotin #1
      allergic asthma humans #1
      192218 #1
      media symptoms #1
      ses food #1
      nrf2interacting nutrients #1
      allergic telemedicine #1
      response composite definition #1
      thickness basement membrane #1
      oleaceae pollens #1
      asthmacontrol #1
      standardized dermatophagoides #1
      technologyhealth #1
      mizolastine release #1
      global allergy #1
      exogenous 15shete #1
      prior covid19 vaccination #1
      rit protocol #1
      bdp separate administration #1
      cell survival icos #1
      copd interasma #1
      ecadherin expression dexamethasone #1
      rhinitis allergic sensitization #1
      copd media coverage #1
      monotherapy medication #1
      fibronectin release tgfbeta #1
      increase lactate dehydrogenase #1
      narghiles passive smokers #1
      fractionated igg patients #1
      multimorbidity polysensitization #1
      internal size #1
      safety mpazeflu #1
      peaks searches #1
      aas score #1


      Prominent publications by JeanClaude Bousquet

      KOL-Index: 25225

      BACKGROUND: Eczema, rhinitis, and asthma often coexist (comorbidity) in children, but the proportion of comorbidity not attributable to either chance or the role of IgE sensitisation is unknown. We assessed these factors in children aged 4-8 years.

      METHODS: In this prospective cohort study, we assessed children from 12 ongoing European birth cohort studies participating in MeDALL (Mechanisms of the Development of ALLergy). We recorded current eczema, rhinitis, and asthma from ...

      Known for 4 Years | Rhinitis Eczema | Children Asthma | Age 8 | Diseases Child
      KOL-Index: 20516

      Quality of life has been found to be impaired both in patients with asthma and in patients with allergic rhinitis, but the relative burden of these diseases has not been investigated. We analyzed answers to the SF-36 questionnaire from 850 subjects recruited in two French centers participating in the European Community Respiratory Health Survey, a population-based study of young adults. Both asthma and allergic rhinitis were associated with an impairment in quality of life. However, 78% ...

      Known for Allergic Rhinitis | Life Asthma | Impairment Quality | Social Activities
      KOL-Index: 19165

      WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT: • The topical second generation anti-histamine azelastine hydrochloride (AZE) and the potent corticosteroid fluticasone propionate (FP) are well established first-line treatments in allergic rhinitis (AR). • MP29-02, a novel intranasal AZE and FP formulation, has been shown to control AR symptoms faster and better than standard intranasal AZE or FP. • The systemic bioavailabilities of marketed AZE and FP nasal spray products have been established ...

      Known for Aze Fp | Nasal Spray | Fluticasone Propionate | Mp29 02 | Rhinitis Allergic
      KOL-Index: 17959

      BACKGROUND: Allergic Rhinitis and its Impact on Asthma in collaboration with the World Health Organization initiative reclassified allergic rhinitis, like asthma, by duration and severity. The Xyzal in Persistent Rhinitis Trial is the first large, long-term clinical trial studying patients with persistent rhinitis as defined by Allergic Rhinitis and its Impact on Asthma.

      OBJECTIVES: Two primary objectives were defined: comparison of the Rhinoconjunctivitis Quality of Life Questionnaire ...

      Known for Allergic Rhinitis | Quality Life | Comorbidities Costs | Levocetirizine Placebo | Impact Asthma
      KOL-Index: 16505

      BACKGROUND: Patients with severe persistent asthma who are inadequately controlled despite Global Initiative for Asthma (GINA) 2002 step 4 therapy are a challenging population with significant unmet medical need. We determined the effect of omalizumab on clinically significant asthma exacerbations (requiring systemic corticosteroids) in the first omalizumab study to exclusively enrol patients from this difficult-to-treat patient population.

      METHODS: Following a run-in phase, patients ...

      Known for Inadequately Controlled | Severe Persistent | Add‐on Therapy | Monoclonal Antibodies | Omalizumab Placebo
      KOL-Index: 16369

      BACKGROUND: Previous published analyses have focused on the effect of air pollution on asthma and rhinoconjunctivitis throughout early and middle childhood. However, the role of exposure to air pollution in the development of childhood and adolescent asthma and rhinoconjunctivitis remains unclear. We aimed to assess the longitudinal associations between exposure to air pollution and development of asthma and rhinoconjunctivitis throughout childhood and adolescence.

      METHODS: We did a ...

      Known for Air Pollution | Development Asthma | Birth Cohort | Childhood Adolescence | Associations Exposure
      KOL-Index: 16277

      BACKGROUND: A genomewide association study has shown an association between variants at chromosome 17q21 and an increased risk of asthma. To elucidate the relationship between this locus and disease, we examined a large, family-based data set that included extensive phenotypic and environmental data from the Epidemiological Study on the Genetics and Environment of Asthma.

      METHODS: We tested 36 single-nucleotide polymorphisms (SNPs) in the 17q21 region in 1511 subjects from 372 families ...

      Known for Onset Asthma | 17q21 Variants | Environmental Tobacco Smoke | Early Life | Human Pair
      KOL-Index: 16262

      BACKGROUND: Eczema, asthma, and rhinitis affect a large proportion of children, but their prevalence varies with age. IgE antibodies are also common in the pediatric population. However, the links between IgE, disease, and trajectories are unclear.

      OBJECTIVE: To better understand the links between sensitization and disease, we studied IgE sensitization ever in relation to eczema, asthma, and rhinitis, in children followed up to 16 years of age.

      METHODS: From the Swedish population-based ...

      Known for Asthma Rhinitis | Children Eczema | 16 Years | Ige Sensitization | Prevalence Age
      KOL-Index: 15896

      In the present study, we show that IL-2, IL-4, IL-7, and IL-15 are able to induce functional CXCR4 surface expression on resting in vitro-generated CD4+ CXCR4- CCR7+ memory T cells. Cytokine-mediated induction of CXCR4 expression was associated with an increase in CXCR4 transcription, enhanced stromal-derived factor-1-induced T cell migration in vitro, and increased susceptibility of these cells to infection with X4 strains of HIV-1. CXCR4 expression could also be induced through an ...

      Known for Cxcr4 Expression | Chemokine Receptors | Cell Surface | X4 Strains | Cd4 Antigens
      KOL-Index: 15705

      BACKGROUND: Cupressaceae pollen allergy is a worldwide pollinosis, but its in vitro diagnosis is notoriously difficult. The Basotest is a newly available in vitro test for the detection of allergen-specific IgE based on the level of cellular activation of basophils by using flow cytometry.

      OBJECTIVES: The Basotest was compared with the measurement of cypress pollen-specific IgE in highly selected patients.

      METHODS: We analyzed 34 patients allergic to cypress pollen selected on the basis ...

      Known for Cypress Pollen | Vitro Diagnosis | Patients Basotest | Seasonal Sensitivity | Basophils Flow Cytometry
      KOL-Index: 15492

      OBJECTIVES: To assess the effect of montelukast versus salmeterol added to inhaled fluticasone propionate on asthma exacerbation in patients whose symptoms are inadequately controlled with fluticasone alone. Design and setting A 52 week, two period, double blind, multicentre trial during which patients whose symptoms remained uncontrolled by inhaled corticosteroids were randomised to add montelukast or salmeterol.

      PARTICIPANTS: Patients (15-72 years; n = 1490) had a clinical history of ...

      Known for Asthma Exacerbation | Montelukast Salmeterol | Patients Symptoms | Beta Agonist | 1 Year
      KOL-Index: 14782

      BACKGROUND: Lung deposition is crucial for asthma treatment. However, there is no study comparing the potential role of lung co-deposition of combination therapy (inhaled corticosteroid and long-acting beta2 agonist) in the same inhaler. In moderate to severe asthmatics, an extra-fine hydrofluoroalkane combination of beclomethasone dipropionate and formoterol given via a single pressurised metered-dose inhaler (pMDI) was compared with beclomethasone dipropionate chlorofluorocarbon (CFC) ...

      Known for Single Inhaler | Lung Function | Asthma Control | Beclomethasone Dipropionate | Formoterol Combination
      KOL-Index: 14599

      STUDY OBJECTIVE: To determine baseline characteristics predictive of response to omalizumab, an anti-IgE antibody, in patients with allergic asthma.

      DESIGN: Pooled analysis of two multicenter, double-blind, randomized, placebo-controlled phase III studies with omalizumab.

      PATIENTS: One thousand seventy allergic asthma patients symptomatic despite moderate-to-high doses (mean, 725 micro g/d) of inhaled beclomethasone dipropionate (BDP).

      INTERVENTIONS: Omalizumab (n = 542) or placebo (n = ...

      Known for Response Omalizumab | Allergic Asthma | Monoclonal Antibodies | 16 Weeks | Ige Antibody
      KOL-Index: 14575

      Histamine is the primary mediator involved the pathophysiology of allergic rhinitis and chronic urticaria, and this explains the prominent role that histamine H(1)-receptor antagonists have in the treatment of these disorders. However, histamine is clearly not the only mediator involved in the inflammatory cascade. There is an emerging view that drugs which can inhibit a broader range of inflammatory processes may prove to be more effective in providing symptomatic relief in both ...

      Known for Allergic Rhinitis | Chronic Urticaria | Paf Receptors | Clinical Trials Rupatadine | Symptomatic Relief

      Key People For Allergic Rhinitis

      Top KOLs in the world
      JeanClaude Bousquet
      allergic rhinitis asthma control chronic respiratory diseases
      Giorgio Walter Canonica
      allergic rhinitis severe asthma sublingual immunotherapy
      Eli O Meltzer
      allergic rhinitis fluticasone propionate united states
      Paul B Van Cauwenberge
      allergic rhinitis nasal polyps chronic rhinosinusitis
      Claus Bachert
      nasal polyps chronic rhinosinusitis allergic rhinitis
      Alkis G Togias
      allergic rhinitis peanut allergy infectious diseases

      JeanClaude Bousquet:Expert Impact

      Concepts for whichJeanClaude Bousquethas direct influence:Allergic rhinitis,  Perennial rhinitis,  Asthma control,  Chronic respiratory diseases,  Allergic diseases,  Severe asthma,  Rhinitis allergic,  Allergen immunotherapy.

      JeanClaude Bousquet:KOL impact

      Concepts related to the work of other authors for whichfor which JeanClaude Bousquet has influence:Allergic rhinitis,  Severe asthma,  Chronic rhinosinusitis,  Airway inflammation,  Nasal polyps,  Atopic dermatitis,  Nitric oxide.



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      Allergology and Immunology, Fraunhofer Institute for Translational Medicine and Pharmacology (ITMP), Berlin, Germany | Department of Dermatology and Allergy, Comprehensive Allergy Center, Berlin Institute of Health, Berlin, Germany | Charité, Univeer

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