Carol Muehleman: Influence Statistics

Carol Muehleman

Carol Muehleman

Rush University Medical Center, Chicago, Illinois, USA | Department of Biochemistry, Rush University Medical Center, 600 S Paulina St, 60612, Chicago, IL, USA | Department of ...


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Carol Muehleman: Expert Impact

Concepts for which Carol Muehleman has direct influence: Articular cartilage , Disc degeneration , Bone density , Disc height , Cartilage degeneration , Cartilage damage , Diffraction enhanced imaging .

Carol Muehleman: KOL impact

Concepts related to the work of other authors for which for which Carol Muehleman has influence: Intervertebral disc , Articular cartilage , Nucleus pulposus , Annulus fibrosus , Ivd degeneration , Extracellular matrix , Subchondral bone .

KOL Resume for Carol Muehleman

Year
2021

Rush University Medical Center, Chicago, Illinois, USA

2018

Department of Biochemistry, Rush University Medical Center, 600 S Paulina St, 60612, Chicago, IL, USA

2014

Biochemistry, Rush University Medical Center, Chicago, IL

2012

Rush University Medical Center Department of Biochemistry Chicago Illinois

2011

Department of Biochemistry, Rush University Medical Center, Cohn Research Building, Room 506, 1753 W. Harrison Street, Chicago, Illinois 60612

2010

Department of Biochemistry, Rush University Medical Center, Chicago, IL.

Rush University Medical Center, Chicago, Illinois

2009

Department of Biochemistry, Rush University Medical Center, Chicago, IL, United States

Biochemistry, Rush Medical College, Chicago, IL 60612, USA.

2008

Department of Biochemistry, Rush University Medical Center, 1735 West Harrison Street, Chicago, IL 60612

Rush University Medical Center, Chicago, IL

2007

From the Departments of *Orthopedic Surgery, †Biochemistry, and ‡Anatomy, Rush Medical College at Rush University Medical Center, Chicago IL; and §Department of Orthopedic Surgery, Toyama University, Toyama, Japan. Drs. Abe and Akeda contributed equally to this manuscript.

Department of Biochemistry, Rush University Medical Center, Cohn Room 524, 1735 W.Harrison St., Chicago, IL 60612, USA

2006

Department of Biochemistry, Rush Medical College at Rush University Medical Center, Chicago, IL, USA

Rush University Medical Center, Chicago, Illinois 60616

2005

Rush Medical College (USA)

2004

Department of Anatomy and Cell Biology, Rush University Medical Center, Chicago, IL 60612, USA.

Rush Medical College, Chicago, IL

2003

Department of Anatomy, Rush Medical College, Chicago, Illinois

2002

Dept. Biochemistry , Rush Med. College , Chicago, IL, 60612,

Rush Medical College, Chicago, IL, USA

2000

Department of Anatomy and Department of Biochemistry, Rush Medical College, Rush‐Presbyterian‐St Lukes Medical Center, Chicago, IL, USA

From Dr. W. M. Scholl College of Podiatric Medicine, Chicago, IL and Thorek Hospital and Medical Center, Chicago, IL.

1999

Department of Basic Biomedical Sciences, Scholl College of Podiatric Medicine, Chicago, IL, USA

1998

Department of Basic Biomedical Sciences, Scholl College of Pediatric Medicine, Chicago, IL.

1997

Basic Biomedical Science Department, Dr. W. M. Scholl College of Podiatric Medicine, 1001 North Dearborn, Chicago, Illinois 60610, U.S.A.

Dr. William M. Scholl College of Podiatric Medicine, Chicago, IL 60610, USA.

1995

Department of Anatomical Sciences, Dr. William M. Scholl College of Podiatric Medicine, Chicago, IL, USA.

1990

Department of Anatomical Sciences, Dr. William M. Scholl College of Podiatric Medicine, Chicago, Illinois 60610.

Prominent publications by Carol Muehleman

KOL-Index: 19094 . STUDY DESIGN: In vivo study of the effect of injection of osteogenic protein-1 (OP-1) on a rabbit anular needle puncture model of intervertebral disc (IVD) degeneration. OBJECTIVE: To study radiographic, magnetic resonance imaging (MRI), biochemical, and histologic changes in the rabbit IVD after injection of OP-1 into the nucleus pulposus in a needle puncture disc degeneration ...
Known for Disc Height | Anular Puncture | Nucleus Pulposus | Growth Factors
KOL-Index: 16104 . STUDY DESIGN: In vitro studies of the effects of proinflammatory cytokines on the production of nerve growth factor (NGF) by human intervertebral disc (IVD) cells. OBJECTIVE: To determine the constitutive expression and production of NGF and the effect of cytokines on the expression of NGF by human IVD cells. SUMMARY OF THE BACKGROUND DATA: NGF may play a role in the collateral sprouting ...
Known for Proinflammatory Cytokines | Disc Cells | Nerve Growth Factor | Expression Ngf
KOL-Index: 11765 . STUDY DESIGN: An in vivo study to radiographically and histologically assess a new method of induction of disc degeneration. OBJECTIVE.: To establish a reproducible rabbit model of disc degeneration by puncturing the anulus with needles of defined gauges and to compare it to the classic stab model. SUMMARY OF BACKGROUND DATA: New treatment approaches to disc degeneration are of great ...
Known for Disc Degeneration | Needle Puncture | Rabbit Model | Magnetic Resonance
KOL-Index: 10806 . INTRODUCTION: The etiology of degenerative disc disease is unknown. Several investigators have reported the presence of proteolytic enzymes, such as the matrix metalloproteinase (MMP) and ADAMTS (a disintegrin and metalloprotease with thrombospondin-like repeats) families, in degenerated human discs. Glasson and colleagues recently reported that a significant reduction occurs in the ...
Known for Intervertebral Disc | Rna Sirna | Matrix Metalloproteinase | Adamts5 Small
KOL-Index: 10604 . BACKGROUND: We sought to determine whether symptomatic medial knee osteoarthritis is associated with aberrant loading across the foot during gait. METHODS: Twenty-five individuals with medial knee osteoarthritis were compared with 25 controls. Knee radiographs and Western Ontario and McMaster Universities Arthritis Index questionnaires were obtained. Participants walked barefoot over ...
Known for Knee Osteoarthritis | Foot Center | Pressure Medial | Western Ontario
KOL-Index: 10548 . STUDY DESIGN: In vitro studies on the effects of recombinant human growth and differentiation factor-5 (rhGDF-5) on matrix metabolism of bovine intervertebral disc cells and an in vivo study on the effect of rhGDF-5 in the rabbit anular puncture model. OBJECTIVE: To determine the reparative capacity of rhGDF-5 on the intervertebral disc. SUMMARY OF BACKGROUND DATA: The in vitro and in vivo ...
Known for Intervertebral Disc | Growth Differentiation | Nucleus Pulposus | Vivo Effects
KOL-Index: 10415 . STUDY DESIGN: In vivo histologic study of nerve ingrowth in the rabbit anular-puncture disc degeneration model. OBJECTIVE: To examine innervation of intervertebral discs and surrounding tissues in the rabbit anular-puncture model with various magnitudes of injury. SUMMARY OF BACKGROUND DATA: A rabbit anular-puncture model of disc degeneration was recently established. However, to our ...
Known for Disc Degeneration | Nerve Ingrowth | Nucleus Pulposus | Magnetic Resonance Imaging
KOL-Index: 9972 . STUDY DESIGN: In vivo study of the effect of an injection of recombinant human osteogenic protein-1 into degenerated discs induced by chondroitinase ABC. OBJECTIVE: To investigate the efficacy of an injection of recombinant human osteogenic protein-1 to induce the recovery of disc height, and biochemical and histologic repair, in discs degenerated through enzymatic digestion by ...
Known for Disc Height | Osteogenic Protein1 | Degeneration Induced | Bone Morphogenetic
KOL-Index: 9903 . OBJECTIVE: The purpose of this work was to test the effect of inhibition of bone remodeling, through the use of the bisphosphonate, zoledronic acid, on cartilage matrix damage in an animal model of cartilage matrix damage. DESIGN: New Zealand white rabbits were divided into four groups for treatment purposes: (1) untreated controls; (2) injected into one knee joint with the cartilage ...
Known for Zoledronic Acid | Animal Model | Bone Cartilage | Knee Joint
KOL-Index: 9848 . Abstract: The prevalence of osteoarthritis (OA) is higher in some joints than in others. Fibrillation and full-thickness cartilage defects in the knee have been considered to be evidence of developing OA (pre-OA). While similar changes have been reported in the ankle (talocrural joint), the frequency of these changes is much higher than expected if the degeneration represents pre-OA. These ...
Known for Knee Joint | Cartilage Degeneration | Articular Female Humans | Organ Donors
KOL-Index: 9015 . OBJECTIVE: The zonal composition and functioning of adult articular cartilage causes depth-dependent responses to compressive injury. In immature cartilage, shear and compressive moduli as well as collagen and sulfated glycosaminoglycan (sGAG) content also vary with depth. However, there is little understanding of the depth-dependent damage caused by injury. Since injury to immature knee ...
Known for Superficial Zone | Articular Cartilage | Compressive Injury | Matrix Damage
KOL-Index: 8193 . We assessed the distribution and relative immunohistochemical staining intensity of the bone morphogenetic protein-7, osteogenic protein-1 (OP-1), in its pro- and mature forms, and four of its receptors, type I (ALK-2, ALK-3, and ALK-6) and type II in normal adolescent New Zealand White rabbit articular cartilage. Expression of the protein and its receptors was also examined in cartilage ...
Known for Articular Cartilage | Immunohistochemical Localization | Protein Receptors | Bone Morphogenetic
KOL-Index: 7937 . OBJECTIVE: To introduce a novel X-ray technology, diffraction-enhanced X-ray imaging (DEI), in its early stages of development, for the imaging of articular cartilage. DESIGN: Disarticulated and/or intact human knee and talocrural joints displaying both undegenerated and degenerated articular cartilage were imaged with DEI. A series of three silicon crystals were used to produce a highly ...
Known for Articular Cartilage | Ray Imaging | Early Stages | Spatial Resolution
KOL-Index: 7752 . Lipopolysaccharide (LPS) induces matrix degradation and markedly stimulates the production of several cytokines, i.e., interleukin-1β, −6, and −10, by disc cells and chondrocytes. We performed a series of experiments to compare cellular responses of cells from the bovine intervertebral disc (nucleus pulposus and annulus fibrosus) and from bovine articular cartilage to LPS. Alginate beads ...
Known for Articular Chondrocytes | Intervertebral Disc | Nucleus Pulposus | Cell Proliferation
KOL-Index: 7021 . Conventional radiography produces a single image of an object by measuring the attenuation of an x-ray beam passing through it. When imaging weakly absorbing tissues, x-ray attenuation may be a suboptimal signature of disease-related information. In this paper we describe a new phase-sensitive imaging method, called multiple-image radiography (MIR), which is an improvement on a prior ...
Known for Image Radiography | Conventional Xray Sources | Poisson Noise | Higher Angles

Key People For Articular Cartilage

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Jurvelin JURVELIN
articular cartilage trabecular bone mechanical properties
#2
Van C Mow
articular cartilage unconfined compression tissue engineering
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Robert L‐Y Sah
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Alan Jay Grodzinsky
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#5
Ernst Bruno Hunziker
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HEIKKI J HELMINEN
articular cartilage hydrostatic pressure transgenic mice

Rush University Medical Center, Chicago, Illinois, USA | Department of Biochemistry, Rush University Medical Center, 600 S Paulina St, 60612, Chicago, IL, USA | Department of Biochemistry, Rush University Medical Center, 1645 W Harrison St, 5th floor