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    • Kenneth D Brandt
    • Kenneth D Brandt: Influence Statistics

      Kenneth D Brandt

      Kenneth D Brandt

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      Department of Internal Medicine (Rheumatology), University of Kansas Medical Center, Kansas City, KS, USA | Univ. of Kansas Med. Ctr., Kansas City, KS, USA | Dept. of Med., ...

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      Kenneth D Brandt:Expert Impact

      Concepts for whichKenneth D Brandthas direct influence:Articular cartilage,Knee osteoarthritis,Knee pain,Synovial fluid,Joint space narrowing,Glycosaminoglycan synthesis,Anterior cruciate ligament,Contralateral knee.

      Kenneth D Brandt:KOL impact

      Concepts related to the work of other authors for whichfor which Kenneth D Brandt has influence:Knee osteoarthritis,Articular cartilage,Rheumatoid arthritis,Synovial fluid,Hyaluronic acid,Physical activity,Subchondral bone.

      KOL Resume for Kenneth D Brandt

      Year
      2016

      Department of Internal Medicine (Rheumatology), University of Kansas Medical Center, Kansas City, KS, USA

      2014

      Univ. of Kansas Med. Ctr., Kansas City, KS, USA

      2013

      Dept. of Med., Univ. of Kansas Med. Ctr., Fairway, KS, USA

      Kansas University Medical Center Fairway

      2012

      University of Kansas Medical Center, Kansas City, KS, USA

      2011

      University of Kansas Medical Center, Kansas City

      2010

      Affiliations for Committee members' can be found in the following section: Members of the OARSI Treatment Guidelines Committee

      Kansas University Medical Center, Fairway, KS, USA

      2009

      Kansas University Medical Center, 5755 Windsor Drive, Fairway, Kansas City, KS 66205, USA

      2008

      Indiana University School of Medicine, Indianapolis, USA

      University of Edinburgh, Osteoarticular Research Group, The Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh EH16 4TJ, United Kingdom

      2007

      Claude Bernard University, Centre Hospitalier Lyon-Sud, Pierre Benite, Cedex, France

      Indiana University School of Medicine, Indianapolis, Indiana, USA

      New York University School of Medicine, New York, NY

      2006

      Department of Orthopaedics and Sports Medicine, University of Washington, Seattle, Washington, USA

      Indiana University School of Medicine, Indianapolis, IN

      2005

      Department of Medicine and Department of Orthopaedic Surgery, IUSM

      Indiana University School of Medicine, Rheumatology Division, 1110 West Michigan Street, Room LO 545, Indianapolis, IN 46202

      2004

      Rheumatology Division, Indiana University School of Medicine, Indianapolis, IN 46202, USA.

      Indiana University School of Medicine, Indianapolis, Indiana

      2003

      Department of Orthopedic Surgery, Indiana University School of Medicine, Clinical Building, Room 600, 541 Clinical Drive, Indianapolis, IN 46202-5111, USA

      Indiana University School of Medicine and Indiana University Multipurpose Arthritis and Musculoskeletal Diseases Center, Indianapolis, Indiana

      2002

      Rheumatology Division and Multipurpose Arthritis and Musculoskeletal Diseases Center, Indiana University School of Medicine, Indianapolis, IN 46202-5103

      2001

      From the *Indiana University School of Medicine, Indianapolis, IN; the **Rush-Presbyterian-St Luke’s Medical Center, Chicago, IL; †University of South Alabama, Mobile, AL; ‡University of Alabama at Birmingham, Birmingham, AL; §Halifax Clinical Research Institute, Daytona Beach, FL; and ∥Boston Biostatistics, Inc, Framingham, MA.

      Indiana University School of Medicine, USA

      2000

      Professor of Medicine and Head, Rheumatology Division, Indiana University School of Medicine, 541 Clinical Drive, Room 492, Indianapolis, IN 46202

      Department of Medicine, Indiana University School of Medicine, Indianapolis, USA.

      Indiana University School of Medicine, and Indiana University Multipurpose Arthritis and Musculoskeletal Diseases Center, Indianapolis

      1999

      Director, Indiana University Multipurpose Arthritis and Musculoskeletal Diseases Center

      Department of Anatomy, Indiana University School of Medicine, 635 Barnhill Drive, Indianapolis, IN, 46202

      Professor of Medicine and Head, Rheumatology Division, Indiana University School of Medicine

      1998

      Indiana University Multipurpose Arthritis and Musculoskeletal Diseases Center, Rheumatology Division, Indiana University School of Medicine, Indianapolis, Indiana, USA

      1997

      Indiana University Multipurpose Arthritis and Musculoskeletal Diseases Center, Indianapolis, USA

      1996

      Indianapolis, IN, U.S.A.

      1995

      Rheumatology Division, Indiana University School of Medicine, Indianapolis 46202-5111, USA.

      Indiana University School of Medicine, Indianapolis, Indiana, and University of Pennsylvania School of Medicine and Veterans Affairs Medical Center, Philadelphia, Pennsylvania, USA

      1994

      Arthritis Center Indiana University School of Medicine Indianapolis, Indiana 46202

      Department of Anatomy, Indiana University School of Medicine, Rheumatology Division, Indiana University School of Medicine, Indianapolis, Indiana, U.S.A.

      1993

      Professor of Medicine and Head of the Rheumatology Division at Indiana University School of Medicine, Director of Indiana University Specialized Center of Research in Osteoarthritis, and Director of Indiana University Multipurpose Arthritis Center, Indianapolis, Indiana

      1992

      Department of Medicine, the Department of Radiology, and the Rheumatology Division and the Multipurpose Arthritis Center, Indiana University School of Medicine, Indianapolis, Indiana

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      Sample of concepts for which Kenneth D Brandt is among the top experts in the world.
      Concept World rank
      cartilage unloaded sites #1
      dogs aspirin #1
      nsaids reinstitution #1
      older‐adult centers #1
      cruciatedeficient #1
      visit health status #1
      habitually unloaded regions #1
      plateau ray #1
      mcomponents serum #1
      ca2 articular chromatography #1
      doxycycline trial #1
      proteoglycans sodium acetate #1
      intermargin distance examination #1
      osteoarthritic pain efforts #1
      sodium urate vivo #1
      weeks ganglionectomy #1
      mfz operated limbs #1
      osteoarthritis11much #1
      gait increased extension #1
      pain severity subjects #1
      severity meniscus #1
      radiographs parallel #1
      dogs cartilage #1
      cartilage proteoglycan collagens #1
      collagen 1 nacl #1
      proteinpolysaccharides extract #1
      cartilage salicylate #1
      indomethacin glycosaminoglycan synthesis #1
      hemostasis synovitis #1
      topic endpoint determination #1
      hexacetonide iodoacetate injection #1
      jsw tibiofemoral joint #1
      reproducibility jsw #1
      untreated dogs extracts #1
      mtp protocols #1
      proteoglycans keratan sulphate #1
      immobilization protects #1
      amyloid fibrils homology #1
      improvement western ontario #1
      hyaluronate knee #1
      synovial fluid certainty #1
      baseline placebo sleeve #1
      magnitude subunits #1
      leaders discussion #1
      animals iodoacetate injection #1
      ligament transection #1
      type collagen collagens #1
      methods standing #1
      pgc dissolution #1
      degradiation glycosaminoglycans #1
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      Prominent publications by Kenneth D Brandt

      KOL-Index: 22533

      PURPOSE: As a prelude to developing updated, evidence-based, international consensus recommendations for the management of hip and knee osteoarthritis (OA), the Osteoarthritis Research Society International (OARSI) Treatment Guidelines Committee undertook a critical appraisal of published guidelines and a systematic review (SR) of more recent evidence for relevant therapies.

      METHODS: Sixteen experts from four medical disciplines (primary care two, rheumatology 11, orthopaedics one and ...

      Known for Critical Appraisal | Knee Osteoarthritis | Treatment Guidelines | Oarsi Recommendations | Management Hip
      KOL-Index: 19690

      PURPOSE: To develop concise, patient-focussed, up to date, evidence-based, expert consensus recommendations for the management of hip and knee osteoarthritis (OA), which are adaptable and designed to assist physicians and allied health care professionals in general and specialist practise throughout the world.

      METHODS: Sixteen experts from four medical disciplines (primary care, rheumatology, orthopaedics and evidence-based medicine), two continents and six countries (USA, UK, France, ...

      Known for Consensus Guidelines | Knee Osteoarthritis | Management Hip | Based Evidence | Chondroitin Sulphate
      KOL-Index: 16925

      OBJECTIVE: To evaluate progression of joint space narrowing in radiographs of osteoarthritic (OA) knees imaged in both the standing anteroposterior (AP) and the Lyon schuss positions, using alternative methods to measure joint space width (JSW).

      METHODS: Standing AP (extended view) and Lyon schuss (posteroanterior [PA] view, with 20-30 degrees of flexion) radiographic images of 58 OA knees were obtained twice (at baseline and 2 years later). With both methods, fluoroscopy was used to ...

      Known for Joint Space | Lyon Schuss | Osteoarthritic Knee | Tibiofemoral Compartment | Reproducibility Jsw
      KOL-Index: 15720

      BACKGROUND: Glucosamine and chondroitin sulfate are used to treat osteoarthritis. The multicenter, double-blind, placebo- and celecoxib-controlled Glucosamine/chondroitin Arthritis Intervention Trial (GAIT) evaluated their efficacy and safety as a treatment for knee pain from osteoarthritis.

      METHODS: We randomly assigned 1583 patients with symptomatic knee osteoarthritis to receive 1500 mg of glucosamine daily, 1200 mg of chondroitin sulfate daily, both glucosamine and chondroitin ...

      Known for Chondroitin Sulfate | Knee Pain | Patients Osteoarthritis | Combination Glucosamine | Rate Response
      KOL-Index: 14441

      OBJECTIVE: Previous studies of knee osteoarthritis (OA) have yielded variable estimates of the rate of joint space narrowing (JSN) in the standing anteroposterior (AP) radiograph, due largely to longitudinal changes in the alignment of the medial tibial plateau (MTP) and x-ray beam. To characterize this bias, we examined serial radiographs of subjects with knee OA in population-based and clinical OA cohorts from 3 locations in the United States and the United Kingdom.

      METHODS: ...

      Known for Medial Tibial Plateau | Jsn Mtp | Serial Radiographs | Tibial Osteoarthritis | Knee Radiograph
      KOL-Index: 13943

      BACKGROUND: The optimal short-term, symptomatic therapy for osteoarthritis of the knee has not been fully determined. Accordingly, we compared the efficacy of a nonsteroidal antiinflammatory drug, ibuprofen, given in either an antiinflammatory dose (high dose) or an analgesic dose (low dose), with that of acetaminophen, a pure analgesic.

      METHODS: In a randomized, double-blind trial, 184 patients with chronic knee pain due to osteoarthritis were given either 2400 or 1200 mg of ibuprofen ...

      Known for Ibuprofen Acetaminophen | Osteoarthritis Knee | Low Dose | Groups Improvement | Patients Chronic
      KOL-Index: 12953

      Clinical criteria for the classification of patients with hip pain associated with osteoarthritis (OA) were developed through a multicenter study. Data from 201 patients who had experienced hip pain for most days of the prior month were analyzed. The comparison group of patients had other causes of hip pain, such as rheumatoid arthritis or spondylarthropathy. Variables from the medical history, physical examination, laboratory tests, and radiographs were used to develop different sets of ...

      Known for Clinical Criteria | Sensitivity Specificity | Hip Hip Pain | Classification Tree | Osteophytes Patients
      KOL-Index: 12427

      OBJECTIVE: To investigate the inhibition of matrix metalloproteinase 1 (MMP-1), MMP-8, and MMP-13 by doxycycline, and to determine whether the variable hemopexin-like domain of each MMP was responsible for the differences in susceptibility to doxycycline inhibition among these collagenases.

      METHODS: Recombinant human MMP-1 (collagenase 1), MMP-8 (collagenase 2), and MMP-13 (collagenase 3), truncated forms of MMP-8 and MMP-13 lacking the hemopexin-like domain, and a mutant form of ...

      Known for Matrix Metalloproteinase | Mmp8 Mmp13 | Type Collagen | Inhibition Doxycycline | Activity Relationship
      KOL-Index: 12223

      OBJECTIVE: A suspected, but heretofore undemonstrated, limitation of the conventional weight-bearing anteroposterior (AP) knee radiograph, in which the joint is imaged in extension, for studies of progression of osteoarthritis (OA) is that changes in knee pain may affect extension, thereby altering the apparent thickness of the articular cartilage. The present study was undertaken to examine the effect of changes in knee pain of varying magnitudes on radiographic joint space width (JSW) ...

      Known for Knee Pain | Conventional Standing | Joint Space Width | Articular Cartilage | Longitudinal Studies
      KOL-Index: 11745

      We examined standing knee radiographs of 92 patients who had chronic knee pain and radiographic evidence of mild or moderate osteoarthritis (OA) according to the Kellgren and Lawrence (K/L) criteria. Because the K/L criteria overemphasize osteophytosis relative to joint space narrowing (JSN), we graded OA severity also with a scoring system that placed greater emphasis on JSN than on osteophytes. In each case, the articular cartilage was visualized directly at arthroscopy. Of 17 patients ...

      Known for Articular Cartilage | Joint Space Narrowing | Knee Osteoarthritis | Radiographic Grading | Arthroscopic Evidence
      KOL-Index: 11670

      OBJECTIVE: To confirm preclinical data suggesting that doxycycline can slow the progression of osteoarthritis (OA). The primary outcome measure was joint space narrowing (JSN) in the medial tibiofemoral compartment.

      METHODS: In this placebo-controlled trial, obese women (n = 431) ages 45-64 years with unilateral radiographic knee OA were randomly assigned to receive 30 months of treatment with 100 mg doxycycline or placebo twice a day. Tibiofemoral JSN was measured manually in ...

      Known for 30 Months | Joint Pain | Contralateral Knee | Progression Osteoarthritis | Preclinical Data
      KOL-Index: 11398

      OBJECTIVE: Recent studies using various standardized radiographic acquisition techniques have demonstrated the necessity of reproducible radioanatomic alignment of the knee to assure precise measurements of medial tibiofemoral joint space width (JSW). The objective of the present study was to characterize the longitudinal performance of several acquisition techniques with respect to long-term reproducibility of positioning of the knee, and the impact of changes in positioning on the rate ...

      Known for Serial Radiographs | Osteoarthritic Knee | Jsn Subjects | Alignment Medial | Longitudinal Studies

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      Department of Internal Medicine (Rheumatology), University of Kansas Medical Center, Kansas City, KS, USA | Univ. of Kansas Med. Ctr., Kansas City, KS, USA | Dept. of Med., Univ. of Kansas Med. Ctr., Fairway, KS, USA | Kansas University Medical Cente

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