William C. Meyers

William C. Meyers

From The Departments Of Surgery, Physiology And Otolaryngology, Duke University Medical Center, And Veterans Administration Center, Durham, North Carolina.

Direct Impact

Concepts for which William C Meyers has direct influence:

athletic pubalgia
laparoscopic cholecystectomy
cold ischemia
groin pain
bile flow
sports hernia
core muscle

External impact

Concepts related to the work of other authors for which William C Meyers has influence:

athletic pubalgia
magnetic resonance
bile flow
prairie dogs
sports hernia
groin pain
gallstone formation

Prominent publications by William C. Meyers

KOL-Index: 89 Laparoscopic cholecystectomy has become the procedure of choice for surgical removal of the gallbladder. The most significant complication of this new technique is injury to the bile duct. Twelve cases of bile duct injury during laparoscopic cholecystectomy were reviewed. Eight injuries were of a classic type: misidentification of the common duct for the cystic duct, resection of part of the ...
Known for
Successful Direct Duct Repair | Bile Duct Injury | Adequate Biliary Drainage | Persistent Diffuse Abdominal Pain
KOL-Index: 61 Magnetic resonance imaging (MRI) has become the standard imaging modality for activity-related groin pain. Lesions, including rectus abdominis/adductor aponeurosis injury and osteitis pubis, can be accurately identified and delineated in patients with clinical conditions termed athletic pubalgia, core injury, and sports hernia. A dedicated noncontrast athletic pubalgia MRI protocol is easy ...
Known for
Musculoskeletal Imaging | Groin Pain | Injury Sports | Lesions Mri
KOL-Index: 40 BACKGROUND: In living donor liver transplantation (LDLTx) organ procurement is usually well controlled, and allows to assess liver preservation and graft function under standardized conditions. Because publications on histidine-tryptophan-ketoglutarate (HTK) solution are limited, we prospectively studied its safety and efficacy in a consecutive series of LDLTx. METHODS: Twenty-four patients ...
Known for
Safety Living | Perfusion Htk
KOL-Index: 37 Gallbladder Na+ absorption and biliary Ca2+ are both increased during gallstone formation and may promote cholesterol nucleation. Na+/H+ exchange (NHE) is a major pathway for gallbladder Na+ transport. Ca2+-dependent second messengers, including protein kinase C (PKC), inhibit basal gallbladder Na+ transport. Multiple PKC isoforms with species- and tissue-specific expression have been ...
Known for
Nhe Isoform | Activity Basal | Expression Pkc | Major Pathway
KOL-Index: 35 Despite its relative safety (in comparison with surgery), and undoubted role in many clinical circumstances, biliary sphincterotomy is the most dangerous procedure routinely performed by endoscopists. Complications occur in about 10% of patients; 2 to 3% have a prolonged hospital stay, with a risk of dying. This document is an attempt to provide guidelines for prevention and management of ...
Known for
Endoscopists | 2 3 | Prolonged Stay | Sphincterotomy
KOL-Index: 29 BACKGROUND: Gallbladder Na+ and H2O absorption are increased prior to gallstone formation and may promote cholesterol nucleation. Na+/H+ exchange (NHE) isoforms NHE2 and NHE3 are involved in gallbladder Na+ transport in prairie dogs. We examined whether increased gallbladder Na+ absorption observed during early gallstone formation is the result of NHE up-regulation. MATERIALS AND METHODS: ...
Known for
Nhe Proteins | Increased Vmax | Native Gallbladder | Precrys Cholesterol
KOL-Index: 25 OBJECTIVE: To investigate the effects and related mechanisms of miR-204 on fracture healing. MATERIALS AND METHODS: Mouse osteoblastic cell line MC3T3-E1 was used in our experiment. Three groups were established to investigate the potential function between miR-204 and osteoblastic cells: miR-NC group (negative control), miR-204 mimics group (MC3T3-E1 cells transfected with miR-204 mimics) ...
Known for
Promotes Fracture | Osterix | Mimics Inhibitor | Mouse Osteoblastic Mc3t3-E1
KOL-Index: 25 Endothelin is a potent hepatic vasoconstrictor. We evaluated the role of an endothelin antagonist in hepatic ischemia/reperfusion injury. Bosentan, a novel endothelin receptor antagonist, was infused directly into the portal vein prior to cold ischemia and immediately on reperfusion, in five porcine livers. Five other pigs underwent routine liver harvest and reperfusion without bosentan ...
Known for
Antagonist Hepatic | Augmented Biliary Response | Routine Liver Harvest | Bosentan-Treated Organs
KOL-Index: 22 BACKGROUND: Cold preservation produces hepatic injury that is difficult to assess during early reperfusion. The value of reperfusion plasma choline phospholipid in predicting subsequent organ function is documented in these studies. MATERIALS AND METHODS: Livers of female Yorkshire pigs were prepared for transplantation. After 2 h of cold ischemia the reperfusion plasma was evaluated for ...
Known for
Equivalent Increases | Efflux Reperfusion | Sorbitol Dehydrogenase | Hepatic Hemodynamics
KOL-Index: 22 Glucagon and insulin are postulated to be physiologic regulators of hepatic biliary secretion. Effects of these hormones were studied following orthotopic transplantation. Five adult hepatic graft recipients had triple lumen t-tubes placed at the time of surgery and were studied 3 months after surgery. Experiments were performed after cholangiographic confirmation of t-tube placement and ...
Known for
2 Micrograms | Triple Lumen T-Tubes | Hepatic Biliary | T-Tube Placement

From the Departments of Surgery, Physiology and Otolaryngology, Duke University Medical Center, and Veterans Administration Center, Durham, North Carolina.

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