• Disease
  • Mycobacterium
  • Mycobacterium Tuberculosis
  • Martien Willem Borgdorff

    Prominent publications by Martien Willem Borgdorff

    KOL Index score: 16325

    BACKGROUND: Studies have shown that the Mycobacterium tuberculosis Beijing genotype is an emerging pathogen that is frequently associated with drug resistance. This suggests that drug resistant Beijing strains have a relatively high transmission fitness compared to other drug-resistant strains.

    METHODS AND FINDINGS: We studied the relative transmission fitness of the Beijing genotype in relation to anti-tuberculosis drug resistance in a population-based study of smear-positive ...

    Also Ranks for: Beijing Genotype |  mycobacterium tuberculosis |  streptomycin resistance |  eai strains |  drug resistant
    KOL Index score: 15108

    BACKGROUND: In Kenya, coverage of antiretroviral therapy (ART) among people with HIV infection has increased from 7% in 2006, to 57% in 2016; and, in western Kenya, coverage of voluntary medical male circumcision (VMMC) increased from 45% in 2008, to 72% in 2014. We investigated trends in HIV prevalence and incidence in a high burden area in western Kenya in 2011-16.

    METHODS: In 2011, 2012, and 2016, population-based surveys were done via a health and demographic surveillance system and ...

    Also Ranks for: Hiv Incidence |  western kenya |  antiretroviral therapy |  male circumcision |  art vmmc
    KOL Index score: 13566

    The authors determined the positive predictive value (PPV) for progression to tuberculosis (TB) of two interferon-gamma release assays (IGRAs), QuantiFERON-TB Gold In-tube (QFT-GIT) and T-SPOT.TB, and the tuberculin skin test (TST) in immigrants contacts. Immigrant close contacts of sputum smear-positive TB patients were included when aged > or =16 yrs and their TST result was > or =5 mm 0 or 3 months after diagnosis of the index patient. Contacts were followed for the next 2 yrs for ...

    Also Ranks for: Qftgit Tst |  progression tuberculosis |  reagent kits |  5 mm |  positive predictive
    KOL Index score: 12857

    BACKGROUND: Hospitals with inadequate infection control are risky environments for the emergence and transmission of tuberculosis (TB). We evaluated TB infection control practices, and the prevalence of latent TB infection (LTBI) and TB disease and risk factors in health care workers (HCW) in TB centers in Henan province in China.

    METHODS: A cross-sectional survey was conducted in 2005. To assess TB infection control practices in TB centers, checklists were used. HCW were tuberculin skin ...

    Also Ranks for: Infection Control |  prevalence ltbi |  health workers |  china cross |  personnel humans
    KOL Index score: 12406

    BACKGROUND: Tens of millions of children are exposed to Mycobacterium tuberculosis globally every year; however, there are no contemporary estimates of the risk of developing tuberculosis in exposed children. The effectiveness of contact investigations and preventive therapy remains poorly understood.

    METHODS: In this systematic review and meta-analysis, we investigated the development of tuberculosis in children closely exposed to a tuberculosis case and followed for incident disease. ...

    Also Ranks for: Tuberculosis Children |  preventive therapy |  5 years |  infection incidence |  risk developing
    KOL Index score: 11938

    BACKGROUND: We conducted a tuberculosis (TB) prevalence survey and evaluated the screening methods used in our survey, to assess if screening in TB prevalence surveys could be simplified, and to assess the accuracy of screening algorithms that may be applicable for active case finding.

    METHODS: All participants with a positive screen on either a symptom questionnaire, chest radiography (CXR) and/or sputum smear microscopy submitted sputum for culture. HIV status was obtained from ...

    Also Ranks for: Prevalence Surveys |  symptom screening |  chest radiography |  hiv status |  sensitivity cxr
    KOL Index score: 11774

    OBJECTIVE: To determine the prevalence of syphilis and the prevalence and incidence of self-reported STD syndromes in the population of Mwanza Region, North-Western Tanzania.

    METHODS: A population-based random cluster sample survey, stratified by rural, roadside or urban residence, of 4173 individuals aged 15-54 years was performed in 1990-91. The seroprevalence of syphilis (using TPHA and RPR) and the prevalence and incidence of self-reported genital ulcer syndrome (GUS) and genital ...

    Also Ranks for: Prevalence Incidence |  sexually transmitted |  mwanza region |  female genital diseases |  western tanzania
    KOL Index score: 11542

    BACKGROUND: Challenges exist regarding TB infection control and TB in hospital-based healthcare workers in South Africa. However, few studies report on TB in non-hospital based healthcare workers such as primary or community healthcare workers. Our objectives were to investigate the implementation of TB infection control measures at primary healthcare facilities, the smear positive TB incidence rate amongst primary healthcare workers and the association between TB infection control ...

    Also Ranks for: Healthcare Workers |  south africa |  infection control |  health facilities |  measures primary
    KOL Index score: 11407

    OBJECTIVE: Tuberculosis and smoking are both significant public health problems. The association between passive smoking and Mycobacterium tuberculosis infection is not well documented. The objective of this study was to examine the influence of passive smoking on M. tuberculosis infection in children.

    METHODS: A community survey was conducted in 15% of addresses in 2 adjacent low-income suburbs in Cape Town, South Africa. All children (< 15 years of age) and their adult household ...

    Also Ranks for: Passive Smoking |  tuberculosis infection |  south africa |  children household |  tuberculin test
    KOL Index score: 11271

    BACKGROUND: Studies have suggested that the Mycobacterium tuberculosis Beijing genotype causes more severe clinical disease and higher treatment failure rates with standard regimens, possibly in association with an increased risk of acquiring drug resistance. We studied the effect of genotype on treatment failure in a rural area in Vietnam where multidrug resistance is strongly associated with the Beijing genotype.

    METHODS: In a population-based prospective cohort study, patients with ...

    Also Ranks for: Beijing Genotype |  mycobacterium tuberculosis |  treatment failure |  multidrug resistance |  dna fingerprinting
    KOL Index score: 11225

    BACKGROUND: Mortality from TB continues to be a global public health challenge. TB ranks alongside Human Immunodeficiency Virus (HIV) as the leading infectious causes of death globally. HIV is a major driver of TB related morbidity and mortality while TB is the leading cause of mortality among people living with HIV/AIDS. We sought to determine excess mortality associated with HIV and the effect of antiretroviral therapy on reducing mortality among tuberculosis patients in ...

    Also Ranks for: Tuberculosis Patients |  risk factors mortality |  hiv art |  tbassociated deaths |  human immunodeficiency virus
    KOL Index score: 11123

    OBJECTIVE: To estimate the prevalence of tuberculosis in Viet Nam with data from a population-based survey, compare it with the prevalence estimated by the World Health Organization, and identify major demographic determinants of tuberculosis prevalence.

    METHODS: A cross-sectional survey with multistage cluster sampling, stratified by urban, rural and remote areas, was done in 2006-2007 in 70 communes. All inhabitants aged > or = 15 years were invited for cough and chest X-ray ...

    Also Ranks for: Tuberculosis Prevalence |  national survey |  15 years |  smear examination |  health organization
    KOL Index score: 10886

    The prevalence of mutations at amino acid (aa) position 315 in the katG gene of isoniazid (INH)-resistant Mycobacterium tuberculosis isolates in The Netherlands and the mutation's association with the level of INH resistance, multidrug resistance, and transmission were determined. Of 4288 M. tuberculosis isolates with available laboratory results, 295 (7%) exhibited INH resistance. Of 148 aa 315 mutants, 89% had MICs of 5-10 microg/mL, whereas 75% of the other 130 INH-resistant strains ...

    Also Ranks for: Katg Gene |  mycobacterium tuberculosis |  inh resistance |  amino acid |  position 315


    Martien Willem Borgdorff: Influence Statistics

    Sample of concepts for which Martien Willem Borgdorff is among the top experts in the world.
    Concept World rank
    patient qftgit #1
    sputum samples mtb #1
    seeking providers #1
    17718 children #1
    prevalence entry #1
    vietnam low #1
    contact investigations netherlands #1
    sterility needles #1
    national tuberculin survey #1
    4 weeks delay #1
    immigration control policies #1
    blinded expert assessment #1
    prevalent smearpositive case #1
    cxr symptom #1
    syringes knowledge #1
    overestimation coprevalent #1
    fatality tuberculosis #1
    pulmonary patients contacts #1
    2 yrs post #1
    proportion disease #1
    igra ltbi diagnosis #1
    2394 symptomatic adults #1
    tuberculosis deaths hiv #1
    major type point #1
    patients tuberculosis disease #1
    decades insights #1
    tst negative igra #1
    health pulmonary vietnam #1
    contact investigations #1
    screening immigrants #1
    underestimation incident #1
    screened health #1
    1040 pulmonary patients #1
    1468 immigrants #1
    bacteriologic infant #1
    clinical officers experts #1
    guidelines avoidable #1
    new smearpositive cases #1
    analyses patient delay #1
    national tuberculin #1
    values tuberculin #1
    community controls bangladesh #1
    burden order #1
    ltbi preventive therapy #1
    positive styblo #1
    transferout proportion failures #1
    avoidable blood #1
    tspottb contacts #1
    tst netherlands #1
    cxrs experts #1

    Key People For Mycobacterium Tuberculosis

    Top KOLs in the world
    Clifton E Barry Barry
    mycobacterium tuberculosis mycolic acids cell wall
    William R Jacobs
    mycobacterium tuberculosis mycolic acids bacterial genes
    Stewart Thomas Cole
    mycobacterium tuberculosis escherichia coli clostridium perfringens
    Roland Brosch
    mycobacterium tuberculosis tubercle bacilli listeria monocytogenes
    Dick van Soolingen
    mycobacterium tuberculosis beijing genotype dna fingerprinting
    Brigitte Gicquel
    mycobacterium tuberculosis recombinant bcg human macrophages

    Martien Willem Borgdorff:Expert Impact

    Concepts for whichMartien Willem Borgdorffhas direct influence:Mycobacterium tuberculosis,  Beijing genotype,  Mwanza region,  Tuberculosis patients,  South africa,  Hiv incidence,  Prevalence surveys,  Prevalence survey.

    Martien Willem Borgdorff:KOL impact

    Concepts related to the work of other authors for whichfor which Martien Willem Borgdorff has influence:Mycobacterium tuberculosis,  South africa,  Hiv infection,  Beijing genotype,  Molecular epidemiology,  Household contacts.



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    From the Department of Clinical Epidemiology, Biostatistics and Bioinformatics, University of Amsterdam, Amsterdam, The Netherlands. | U.S. Centers for Disease Control and Prevention, Kisumu, Kenya | CDC-Kenya, Kisumu, Kenya. | US Centers for Disease