• Atopic Dermatitis
    • David Joel Margolis
    • David Joel Margolis: Influence Statistics

      David Joel Margolis

      David Joel Margolis

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      Department of Dermatology and Dermatologic Surgery, University of Pennsylvania Medical Center, Philadelphia, Pa; Department of Biostatistics, Epidemiology, and Informatics, ...

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      David Joel Margolis:Expert Impact

      Concepts for whichDavid Joel Margolishas direct influence:Atopic dermatitis,United states,Pressure ulcers,United kingdom,Granuloma annulare,Skin disease,Venous leg ulcers,Patients psoriasis.

      David Joel Margolis:KOL impact

      Concepts related to the work of other authors for whichfor which David Joel Margolis has influence:Atopic dermatitis,Wound healing,Psoriatic arthritis,Global burden,Patients psoriasis,Cardiovascular disease,Mental health.

      KOL Resume for David Joel Margolis


      Department of Dermatology and Dermatologic Surgery, University of Pennsylvania Medical Center, Philadelphia, Pa; Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Medical Center, Philadelphia, Pa.


      Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States

      Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia


      Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia

      Department of Dermatology, Perelman School of Medicine, University of Pennsylvania.


      Department of Dermatology, Perelman School of Medicine,University of Pennsylvania, Philadelphia


      University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.

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      Sample of concepts for which David Joel Margolis is among the top experts in the world.
      Concept World rank
      kir2ds1 kir2ds5 #1
      staphylococcus aureus oropharynx #1
      severity outpatient utilization #1
      wound ultimate goal #1
      prescriptions topical retinoids #1
      hospitalization severe infections #1
      cnv race #1
      pressure ulcer examination #1
      patients wemr #1
      patients population #1
      oral antibiotic pharyngitis #1
      uncommon filaggrin #1
      hoffstad #1
      spironolactone oral antibiotics #1
      mutations white subjects #1
      duration dermatologist confirmation #1
      illness cross health #1
      h5020cmvpdgf‐b #1
      major medical comorbidity #1
      lea rate #1
      saxagliptin rationale #1
      young women acne #1
      tchhl1 pathogenesis #1
      clinical leg #1
      models midlife health #1
      rs1963645 #1
      patient selfreported #1
      wounds standard #1
      dpn diabetes #1
      prepi icc #1
      cardiovascular comorbidities association #1
      394 532 #1
      014089 #1
      examination preventive devices #1
      dermatitis african #1
      asthma increasing frequency #1
      acne pharyngitis #1
      95 autoimmune disease #1
      nondiseased skin #1
      appearance personal lives #1
      prescription allergic events #1
      pressure ulcers photographs #1
      q2053del224 95 #1
      dlqi poscorad #1
      responsiveness patient report #1
      acne monitoring practices #1
      frequency antibiotic prescribing #1
      wound healing diabetics #1
      2893 adults #1
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      Prominent publications by David Joel Margolis

      KOL-Index: 28408

      BACKGROUND: Improving survival and extending the longevity of life for all populations requires timely, robust evidence on local mortality levels and trends. The Global Burden of Disease 2015 Study (GBD 2015) provides a comprehensive assessment of all-cause and cause-specific mortality for 249 causes in 195 countries and territories from 1980 to 2015. These results informed an in-depth investigation of observed and expected mortality patterns based on sociodemographic measures.

      METHODS: ...

      Known for Life Expectancy | Specific Mortality | Global Burden | Population Growth | Total Deaths
      KOL-Index: 24966

      BACKGROUND: Non-fatal outcomes of disease and injury increasingly detract from the ability of the world's population to live in full health, a trend largely attributable to an epidemiological transition in many countries from causes affecting children, to non-communicable diseases (NCDs) more common in adults. For the Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD 2015), we estimated the incidence, prevalence, and years lived with disability for diseases and ...

      Known for Prevalence Incidence | Disability Ylds | Global Burden | Systematic Analysis | Years Lived
      KOL-Index: 23721

      BACKGROUND: Measuring disease and injury burden in populations requires a composite metric that captures both premature mortality and the prevalence and severity of ill-health. The 1990 Global Burden of Disease study proposed disability-adjusted life years (DALYs) to measure disease burden. No comprehensive update of disease burden worldwide incorporating a systematic reassessment of disease and injury-specific epidemiology has been done since the 1990 study. We aimed to calculate ...

      Known for Global Burden | 291 Diseases | Systematic Analysis | Child Child | Disability Ylds
      KOL-Index: 20720

      BACKGROUND: Non-fatal health outcomes from diseases and injuries are a crucial consideration in the promotion and monitoring of individual and population health. The Global Burden of Disease (GBD) studies done in 1990 and 2000 have been the only studies to quantify non-fatal health outcomes across an exhaustive set of disorders at the global and regional level. Neither effort quantified uncertainty in prevalence or years lived with disability (YLDs).

      METHODS: Of the 291 diseases and ...

      Known for Systematic Analysis | Global Burden | Disability Ylds | Prevalence Years | Health Systems
      KOL-Index: 17095

      BACKGROUND: Previous studies suggest that patients hospitalized for psoriasis have an increased frequency of a variety of cardiovascular comorbidities. Limited population-based data exist on this association, and few studies have determined which factors are independently associated with psoriasis.

      OBJECTIVE: We sought to determine whether the prevalence of the major cardiovascular risk factors was higher in mild and severe psoriasis than in patients without psoriasis.

      METHODS: We ...

      Known for Mild Psoriasis | Cardiovascular Risk Factors | 95 Obesity | Hypertension Hyperlipidemia | Systemic Therapy
      KOL-Index: 16479

      OBJECTIVES: We aimed to quantify the risk of major adverse cardiovascular events (MACE) among patients with psoriatic arthritis (PsA), rheumatoid arthritis (RA) and psoriasis without known PsA compared with the general population after adjusting for traditional cardiovascular risk factors.

      METHODS: A population-based longitudinal cohort study from 1994 to 2010 was performed in The Health Improvement Network (THIN), a primary care medical record database in the UK. Patients aged 18-89 ...

      Known for Psoriatic Arthritis | Patients Psoriasis | Major Cardiovascular Events | Risk Mace | Psa Dmard
      KOL-Index: 15611

      BACKGROUND: Measurement of the global burden of disease with disability-adjusted life-years (DALYs) requires disability weights that quantify health losses for all non-fatal consequences of disease and injury. There has been extensive debate about a range of conceptual and methodological issues concerning the definition and measurement of these weights. Our primary objective was a comprehensive re-estimation of disability weights for the Global Burden of Disease Study 2010 through a ...

      Known for Global Burden | Health Outcomes | Study 2010 | Disability Weights | Disease Injury
      KOL-Index: 15572

      BACKGROUND: The relationship between atopic dermatitis (AD), anxiety and depression in the U.S. adult population is not well established.

      OBJECTIVES: To determine the relationship of AD and its severity with symptoms and diagnosis of anxiety and depression in U.S. adults.

      METHODS: A cross-sectional, population-based study of 2893 adults was performed. AD was determined using modified U.K. Diagnostic Criteria.

      RESULTS: Adults with AD vs. those without AD had higher mean Hospital Anxiety ...

      Known for Atopic Dermatitis | Anxiety Depression | Higher Odds | Hads Scores | 95 Confidence Interval
      KOL-Index: 14226

      Venous leg ulcers, which may take months to heal, account for 40-70% of all lower extremity chronic wounds. New treatment options for venous leg ulcers have recently been proposed, and therefore deciding which patients are candidates for these novel-and often expensive-treatments is an important task. Moreover, researchers conducting clinical trials often wish to enroll patients who are unlikely to heal in order to minimize sample sizes needed and research costs. Our purpose was to ...

      Known for 24 Weeks | Venous Leg | Ulcer Area | Multicentre Study | Treatment Percentage
      KOL-Index: 13457

      IMPORTANCE: The National Action Plan for Combating Antibiotic-Resistant Bacteria set a goal of reducing inappropriate outpatient antibiotic use by 50% by 2020, but the extent of inappropriate outpatient antibiotic use is unknown.

      OBJECTIVE: To estimate the rates of outpatient oral antibiotic prescribing by age and diagnosis, and the estimated portions of antibiotic use that may be inappropriate in adults and children in the United States.


      Known for Antibiotic Prescriptions | 1000 Population | United States | Ambulatory Visits | Rates Age
      KOL-Index: 13204

      BACKGROUND: In September, 2015, the UN General Assembly established the Sustainable Development Goals (SDGs). The SDGs specify 17 universal goals, 169 targets, and 230 indicators leading up to 2030. We provide an analysis of 33 health-related SDG indicators based on the Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD 2015).

      METHODS: We applied statistical methods to systematically compiled data to estimate the performance of 33 health-related SDG indicators for 188 ...

      Known for 188 Countries | Global Burden | Health Indicators | Baseline Analysis | Development Goals
      KOL-Index: 13021

      OBJECTIVE: To measure the prevalence and treatment of psoriasis in the United Kingdom.

      DESIGN: Cross-sectional study to determine prevalence and cohort study to determine treatment patterns.

      SETTING: Outpatient practices of general practitioners.

      PATIENTS: We included in the analysis all patients who were registered with a general practitioner in the General Practice Research Database from 1987 to 2002.

      MAIN OUTCOME MEASURES: The prevalence and treatment of psoriasis.

      RESULTS: We ...

      Known for United Kingdom | Prevalence Psoriasis | Child Child | General Practice | Outcome Measures
      KOL-Index: 12870

      BACKGROUND: Atopic dermatitis (AD) is a common skin disease that is characterized by recurrent episodes of itching. Filaggrin (FLG) loss-of-function (FLG null) mutations have been associated with an increased risk of AD.

      OBJECTIVE: We sought to evaluate the effect of individual FLG null mutations on the persistence of AD over time.

      METHODS: We evaluated a multiyear prospective cohort study of children with AD with respect to FLG null mutations (R501X, 2282del4, R2447X, and S3247X). We ...

      Known for Atopic Dermatitis | Longitudinal Cohort | Flg Mutations | Persistence Symptoms | Recurrent Episodes
      KOL-Index: 12845

      BACKGROUND: Structured patient-reported outcomes of atopic dermatitis (AD) severity are not standardized in clinical practice.

      OBJECTIVES: To determine the construct validity, internal consistency, cross-cultural validity and floor or ceiling effects of multiple AD severity assessments.

      METHODS: This is a cross-sectional, population-based study of 2893 adults, including 602 adults who met a modified set of U.K. diagnostic criteria for AD. AD severity was assessed using self-reported ...

      Known for Atopic Dermatitis Severity | Poscorad Poem | Patientoriented Eczema Measure | Reported Outcomes | Dermatitis Scorad
      KOL-Index: 12558

      IMPORTANCE: Research prioritization should be guided by impact of disease.

      OBJECTIVE: To determine whether systematic reviews and protocol topics in Cochrane Database of Systematic Reviews (CDSR) reflect disease burden, measured by disability-adjusted life years (DALYs) from the Global Burden of Disease (GBD) 2010 project.

      DESIGN, SETTING, AND PARTICIPANTS: Two investigators independently assessed 15 skin conditions in the CDSR for systematic review and protocol representation from ...

      Known for Global Burden | Cochrane Database | Skin Disease | Systematic Reviews Cdsr | Protocol Representation

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      Department of Dermatology and Dermatologic Surgery, University of Pennsylvania Medical Center, Philadelphia, Pa; Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania Medical Center, Philadelphia, Pa. | Department of

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