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    • Johnannes Ring
    • Johnannes Ring

      Johnannes Ring

      Department Dermatology and Allergy Biederstein, Technical University Munich, Munich, Germany | Department of Dermatology and Allergy Biederstein, Technical University Munich, ...



      KOL Resume for Johnannes Ring


      Department Dermatology and Allergy Biederstein, Technical University Munich, Munich, Germany


      München, Germany

      Klinik und Poliklinik für Dermatologie und Allergologie am Biederstein, Technische Universität München

      Christine Kühne Center for Allergy Research and Education (CK‐Care), Davos, Switzerland


      Department of Dermatology, SKIN Research Group, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Laarbeeklaan 103, Building D, Room D148, 1090, Brussels, Belgium

      Haut- und Laserzentrum an der Oper, München,

      Medical Association of German Allergists (AEDA), Dreieich, Germany

      Ärzteverband Deutscher Allergologen (AeDA)

      Academia, München.


      Department of Dermatology and Allergy, Technical University of Munich, Biedersteiner Str. 29, 80802, Munich, Germany

      Christine Kühne Center for Allergy Research and Education CK‐CARE, Davos, Switzerland

      Klinik und Poliklinik für Dermatologie und Allergologie am Biederstein der TU München, Biedersteinerstr. 29, D-80802, München, Deutschland


      Department Dermatology and Allergology Biederstein, Technical University Munich, Munchen, Germany

      Christine Kühne‐Center for Allergy Research and Education (CK‐CARE), Davos, Switzerland


      Department of Dermatology, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZB), Brussels, Belgium

      Christine Kühne Center of Allergy Research and Education (CK-CARE), Klinik und Poliklinik für Dermatologie und Allergologie, Technische Universität München


      Hochgebirgsklinik, Davos, Switzerland.

      Christine Kühne Center for Allergy Research and Education CK‐CARE Hochgebirgsklinik Davos Switzerland

      Department of Dermatology and Allergology, Technical University Munich, Munich, Germany

      Klinik und Poliklinik für Dermatologie und Allergologie, Technische Universität München, Biedersteiner Straße 30, 80802, München, Deutschland



      Johnannes Ring: Influence Statistics

      Sample of concepts for which Johnannes Ring is among the top experts in the world.
      Concept World rank
      pleiotrope #1
      eczema preschool girls #1
      role atopic eczema #1
      birth mb #1
      candidiasis exhibit #1
      2000 patient study #1
      filemakerr #1
      bat bromelain hrp #1
      drug allergy passport #1
      immunologische #1
      symptomatic variability #1
      incompatibility patients #1
      impfstoffkomponenten #1
      oral challenge gluten #1
      mepolizumab treatment apt #1
      ökosyndrom #1
      oxytocin angiotensin #1
      patients hacat cells #1
      ige sige cap #1
      lipid mediators eosinophils #1
      annex iiia #1
      allergeninduced itch #1
      hymenoptera venom anaphylaxis #1
      inflammatory skin condition #1
      prevalence gst #1
      irradiation morphea #1
      mikalien #1
      hospitals 1 concentrations #1
      partner disease #1
      psychosomatic counselling #1
      atopischen ekzems #1
      eosinophilicum #1
      sige antibodies ccds #1
      test apt #1
      89 regard #1
      wfrs lcrs #1
      diarrhö #1
      1methylhistamine #1
      flowcast #1
      foods allergic reactions #1
      ves api #1
      allergic disease therapy #1
      betreuungspersonen #1
      concomitant testing #1
      forms allergies #1
      dyshidrotic eczema #1
      allergen carrier #1
      late cutaneous reactions #1
      kiwi extract recipient #1
      psoriasis acd reactions #1


      Prominent publications by Johnannes Ring

      KOL-Index: 18535

      Cultured primary human keratinocytes were screened for their expression of various members of the toll-like receptor (TLR) family. Keratinocytes were found to constitutively express TLR1, TLR2, TLR3, TLR5, and TLR9 but not TLR4, TLR6, TLR7, TLR8, or TLR10 as shown by polymerase chain reaction analysis. The expression of the crucial receptor for signaling of staphylococcal compounds TLR2 was also confirmed by immunohistochemistry, in contrast to TLR4, which showed a negative staining ...

      Known for Human Keratinocytes | Tolllike Receptor | Staphylococcus Aureus | Nuclear Factor | Nitric Oxide
      KOL-Index: 17485

      BACKGROUND: The role of atopy in the pathophysiology of eczema is still under debate. The concept and analyses of the nonatopic and atopic subtypes of eczema have gained increasing interest in recent studies. The course of these subtypes and differences between boys and girls have not been investigated so far.

      OBJECTIVES: To examine the course of nonatopic and atopic eczema in preschool children from Germany with regard to sex.

      METHODS: Repeated cross-sectional studies were performed in ...

      Known for Girls Eczema | 2 Years | Age Onset | Child Preschool | Boys Atopic
      KOL-Index: 17162

      BACKGROUND: The atopy patch test (APT) was proposed to evaluate IgE-mediated sensitizations in patients with atopic eczema (AE).

      OBJECTIVE: The prevalence and agreement with clinical history and specific IgE (sIgE) of positive APT reactions was investigated in six European countries using a standardized method.

      METHODS: A total of 314 patients with AE in remission were tested in 12 study centers on clinically uninvolved, non-abraded back skin with 200 index of reactivity (IR)/g of house ...

      Known for Atopic Eczema | Positive Reactions | Apt Spt | Patch Test | Preschool Dermatitis
      KOL-Index: 15753

      BACKGROUND: Prevalence data for atopic eczema based on a dermatological examination have not so far been available for East and West Germany. Possible differences in the proportions of extrinsic and intrinsic types of eczema, and how far these could explain differences in the prevalence of eczema, need to be clarified.

      OBJECTIVES: To compare the prevalence of atopic eczema in pre-school children between different locations in East and West Germany, and over a period of 7 years, at three ...

      Known for Atopic Eczema | East Germany | Intrinsic Type | Differences Prevalence | 95 Children
      KOL-Index: 14326

      BACKGROUND: A subgroup of patients with atopic eczema exhibits aggravation through contact with aeroallergens. Little is known from population-based studies, however, about the association between the severity of eczematous skin disease and the degree of aeroallergen sensitization.

      OBJECTIVE: We sought to investigate the relationship between IgE-mediated allergic sensitization to aeroallergens and severity of atopic eczema in schoolchildren.

      METHODS: A nested case-control analysis on ...

      Known for Atopic Eczema | Allergen Prevalence | Preschool Dermatitis | Sensitization Severity | Child Child
      KOL-Index: 14212

      BACKGROUND: East-West comparison studies in Europe find higher prevalences of infectious airway diseases and lower prevalences of allergies in eastern areas. Pollution from sulphur dioxide (SO2) or total suspended particles (TSP) are discussed as causes of this difference.

      METHODS: In four differently polluted areas of East Germany where pollution decreased dramatically between 1989 and 1995 cross-sectional studies in about 7-year-old children were repeated every year between 1991 and ...

      Known for East Germany | Time Trends | Total Suspended Particles | West German Children | 5 Years
      KOL-Index: 14191

      Components of the renin angiotensin system, namely renin, angiotensinogen, angiotensin I and II and aldosterone were measured in plasma of patients with hymenoptera venom anaphylaxis (n = 50) and healthy non-allergic controls (n = 25). Patients with a history of anaphylactic reactions to hymenoptera venom who did not undergo immunotherapy showed significantly reduced renin, angiotensinogen, angiotensin I and angiotensin II in plasma as compared with controls (P < 0.05). There was no ...

      Known for Renin Angiotensin | Hymenoptera Venom | Patients Immunotherapy | Living Insect | Healthy Nonallergic Controls
      KOL-Index: 14167

      BACKGROUND: Short-term immunotherapy (STI) can be beneficial for patients who are noncompliant with long-term specific immunotherapy.

      OBJECTIVE: The efficacy and tolerance of STI with seven preseasonal injections of molecular standardized allergens from grass and rye pollen has been investigated in a double-blind, placebo-controlled multicenter study with 87 patients at 12 German University hospitals.

      METHODS: Symptoms of the eyes, nose, and bronchi and use of symptomatic drugs were ...

      Known for Grass Pollen | Molecular Standardized | Allergic Rhinitis | Sti Placebo | Term Immunotherapy
      KOL-Index: 13970

      BACKGROUND: Following vaccination with traditional smallpox vaccines or after exposure to vaccinated individuals, subjects with atopic dermatitis (AD) can develop eczema vaccinatum, a severe disease with disseminated eruption of pustular contagious lesions. Alternative smallpox vaccines with an improved safety profile would address this unmet medical need.

      METHODS: An open-label controlled Phase I clinical trial was conducted to investigate the safety and immunogenicity of modified ...

      Known for Atopic Dermatitis | Smallpox Vaccine | Modified Vaccinia | Safety Immunogenicity | Ankara Mva
      KOL-Index: 13877

      Toll-like receptors (TLRs) are important pattern recognition molecules that activate the nuclear factor (NF)-kappaB pathway leading to the production of antimicrobial immune mediators. As keratinocytes represent the first barrier against exogenous pathogens in human skin, we investigated their complete functional TLR1-10 expression profile. First, reverse transcription-polymerase chain reaction (PCR) analysis revealed a very similar pattern of TLR mRNA expression when comparing freshly ...

      Known for Tolllike Receptor | Primary Keratinocytes | Hacat Cells | Human Skin | Tlr Ligands
      KOL-Index: 13655

      Thyroid hormones have diverse effects on growth and metabolism. Specific "receptor" proteins which bind triiodothyronine and other biologically active analogs and which may be involved in thyroid hormone action have been recently found in nuclei of responsive tissues. This report presents studies of these receptors in rat liver nuclei. Confirming previous reports, a Scatchard analysis of the binding data suggests the reaction, triiodothyronine + specific receptor in equilibrium with ...

      Known for Thyroid Hormone | Nuclear Localization | Binding Characteristics | Receptors Chromatin | Triiodothyronine Animals
      KOL-Index: 13530

      Emerging evidence suggests an important role for human epidermal keratinocytes in innate immune mechanisms against bacterial and viral skin infections. The proinflammatory effect of viral infections can be mimicked by double-stranded RNA (dsRNA). Herein, we demonstrate that keratinocytes express all known dsRNA sensing receptors at a constitutive and inducible level, and that they use several downstream signaling pathways leading to a broad pattern of gene expression, not only ...

      Known for Stranded Rna | Viral Infections | Rig Mda5 | Pattern Recognition Receptors | Irf3 Activation
      KOL-Index: 13400

      BACKGROUND: Polymorphisms in the serine protease inhibitor gene serine peptidase inhibitor Kazal type 5 (SPINK5) and the serine protease kallikrein-related peptidase 7 gene (KLK7) appear to confer risk to eczema in some cohorts, but these findings have not been widely replicated. These genes encode proteins thought to be involved in the regulation of posttranslation processing of filaggrin (FLG), the strongest identified genetic risk factor for eczema to date.

      OBJECTIVES: We sought to ...

      Known for Eczema Risk | Serine Peptidase | Kazal Type | Spink5 Klk7 | Flg Polymorphisms

      Key People For Atopic Eczema

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      Johnannes Ring
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      Jon M Hanifin
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      lung function international study air pollution
      Donald Y M Leung
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      Johnannes Ring:Expert Impact

      Concepts for whichJohnannes Ringhas direct influence:Atopic eczema,  Atopic dermatitis,  West germany,  Histamine release,  Anaphylactoid reactions,  East germany,  Patients atopic eczema,  Atopic diseases.

      Johnannes Ring:KOL impact

      Concepts related to the work of other authors for whichfor which Johnannes Ring has influence:Atopic dermatitis,  Allergic rhinitis,  Food allergy,  Mast cells,  Hypersensitivity reactions,  Skin tests,  Staphylococcus aureus.



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      Department Dermatology and Allergy Biederstein, Technical University Munich, Munich, Germany | Department of Dermatology and Allergy Biederstein, Technical University Munich, Munich, Germany | Technical University of Munich, School of Medicine, Depar

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