• atrial fibrillation

    Prominent publications by Deirdre Anne Lane

    KOL Index score: 21049

    OBJECTIVES: To evaluate the relative effectiveness and cost-effectiveness of a home-based programme of cardiac rehabilitation using the Heart Manual, with centre-based programmes. It also sought to explore the reasons for non-adherence to cardiac rehabilitation programmes.

    DESIGN: An individually randomised trial, with minimisation for age, gender, ethnicity, initial diagnosis and hospital of recruitment. Participants were followed up after 6, 12 and 24 months by questionnaire and ...

    Also Ranks for: Cardiac Rehabilitation |  heart manual |  patients hospital programme |  physical activity |  patient adherence
    KOL Index score: 20456

    IMPORTANCE: The CHA2DS2-VASc score (congestive heart failure, hypertension, age ≥75 years [doubled], diabetes, stroke/transient ischemic attack/thromboembolism [doubled], vascular disease [prior myocardial infarction, peripheral artery disease, or aortic plaque], age 65-75 years, sex category [female]) is used clinically for stroke risk stratification in atrial fibrillation (AF). Its usefulness in a population of patients with heart failure (HF) is unclear.

    OBJECTIVE: To investigate ...

    Also Ranks for: Ischemic Stroke |  vasc score |  heart failure |  death patients |  atrial fibrillation
    KOL Index score: 20372

    OBJECTIVES: Various bleeding risk prediction schemes, such as the Hypertension, Abnormal renal/liver function, Stroke, Bleeding history or predisposition, Labile international normalized Ratio, Elderly, Drugs/alcohol (HAS-BLED), Anticoagulation and Risk Factors in Atrial Fibrillation (ATRIA), and Outcomes Registry for Better Informed Treatment (ORBIT) scores, have been proposed in patients with atrial fibrillation. We compared the relative predictive values of these bleeding risk scores ...

    Also Ranks for: Risk Scores |  orbit bleeding |  atrial fibrillation |  therapeutic range |  hasbled score
    KOL Index score: 20177

    OBJECTIVES: The objective of this study was to compare the predictive performance of bleeding risk-estimation tools in a cohort of patients with atrial fibrillation (AF) undergoing anticoagulation.

    BACKGROUND: Three bleeding risk-prediction schemes have been derived for and validated in patients with AF: HEMORR(2)HAGES (Hepatic or Renal Disease, Ethanol Abuse, Malignancy, Older Age, Reduced Platelet Count or Function, Re-Bleeding, Hypertension, Anemia, Genetic Factors, Excessive Fall ...

    Also Ranks for: Atrial Fibrillation |  bled bleeding |  hemorr2hages atria |  intracranial hemorrhage |  topic risk
    KOL Index score: 20009

    Atrial fibrillation (AF) is a major worldwide public health problem, and AF in association with valvular heart disease (VHD) is also common. However, management strategies for this group of patients have been less informed by randomized trials, which have largely focused on 'non-valvular AF' patients. Thrombo-embolic risk also varies according to valve lesion and may also be associated with CHA2DS2VASc score risk factor components, rather than only the valve disease being causal. Given ...

    Also Ranks for: Valvular Heart Disease |  european society |  patients vhd |  atrial fibrillation |  heart rhythm
    KOL Index score: 18957

    BACKGROUND: The risk of stroke varies considerably across different groups of patients with atrial fibrillation (AF). Antithrombotic prophylaxis for stroke is associated with an increased risk of bleeding. We provide recommendations for antithrombotic treatment based on net clinical benefit for patients with AF at varying levels of stroke risk and in a number of common clinical scenarios.

    METHODS: We used the methods described in the Methodology for the Development of Antithrombotic ...

    Also Ranks for: Antithrombotic Therapy |  oral anticoagulation |  atrial fibrillation |  patients risk |  chads2 score
    KOL Index score: 18393

    BACKGROUND: Both atrial fibrillation and chronic kidney disease increase the risk of stroke and systemic thromboembolism. However, these risks, and the effects of antithrombotic treatment, have not been thoroughly investigated in patients with both conditions.

    METHODS: Using Danish national registries, we identified all patients discharged from the hospital with a diagnosis of nonvalvular atrial fibrillation between 1997 and 2008. The risk of stroke or systemic thromboembolism and ...

    Also Ranks for: Chronic Kidney Disease |  atrial fibrillation |  risk stroke |  patients warfarin |  systemic thromboembolism
    KOL Index score: 17046

    BACKGROUND: Vascular disease (including myocardial infarction and peripheral artery disease) has been proposed as a less well-validated risk factor for stroke in patients with atrial fibrillation. We investigated whether vascular disease is an independent risk factor of stroke/thromboembolism in atrial fibrillation and whether adding vascular disease improves Congestive heart failure, Hypertension, Age 75 years, Diabetes, previous Stroke (CHADS(2)) risk stratification.

    METHODS: By using ...

    Also Ranks for: Vascular Disease |  atrial fibrillation |  stroke risk |  myocardial infarction |  chads2 score
    KOL Index score: 16951

    The concept of net clinical benefit has been used to quantify the balance between risk of ischaemic stroke (IS) and risk of intracranial haemorrhage (ICH) with the use oral anticoagulant therapy (OAC) in the setting of non-valvular atrial fibrillation (AF), and has shown that patients at highest risk of stroke and thromboembolism gain the greatest benefit from OAC with warfarin. There are no data for the new OACs, that is, dabigatran, rivaroxaban and apixaban, as yet. We calculated the ...

    Also Ranks for: Net Clinical Benefit |  modelling analysis |  apixaban dabigatran |  risk stroke |  new oral anticoagulants
    KOL Index score: 16283

    BACKGROUND: According to the latest European guidelines on the management of nonvalvular atrial fibrillation (NVAF), all patients aged ≥ 65 years should be treated with oral anticoagulation (if not contraindicated). Therefore, stroke risk factors should be investigated exclusively in patients with NVAF aged < 65 years.

    METHODS: Patients diagnosed with NVAF in a four-hospital institution between 2000 and 2010 were identified. Event rates of stroke/thromboembolism were calculated according ...

    Also Ranks for: Patients Nvaf |  vascular disease |  atrial fibrillation |  previous stroke |  heart failure
    KOL Index score: 15849

    The current manuscript is the second update of the original Practical Guide, published in 2013 [Heidbuchel et al. European Heart Rhythm Association Practical Guide on the use of new oral anticoagulants in patients with non-valvular atrial fibrillation. Europace 2013;15:625-651; Heidbuchel et al. Updated European Heart Rhythm Association Practical Guide on the use of non-vitamin K antagonist anticoagulants in patients with non-valvular atrial fibrillation. Europace 2015;17:1467-1507]. ...

    Also Ranks for: Patients Noacs |  atrial fibrillation |  practical guide |  heart rhythm |  oral anticoagulants
    KOL Index score: 15048

    The current manuscript is an update of the original Practical Guide, published in June 2013[Heidbuchel H, Verhamme P, Alings M, Antz M, Hacke W, Oldgren J, et al. European Heart Rhythm Association Practical Guide on the use of new oral anticoagulants in patients with non-valvular atrial fibrillation. Europace 2013;15:625-51; Heidbuchel H, Verhamme P, Alings M, Antz M, Hacke W, Oldgren J, et al. EHRA practical guide on the use of new oral anticoagulants in patients with non-valvular ...

    Also Ranks for: Patients Noacs |  practical guide |  valvular atrial |  heart rhythm |  hacke oldgren
    KOL Index score: 14916

    It was the aim of this study to determine the efficacy and safety of vitamin K antagonists (VKAs) and acetylsalicylic acid (ASA) in patients with non-valvular atrial fibrillation (AF), with separate analyses according to predicted thromboembolic and bleeding risk. By individual level-linkage of nationwide registries, we identified all patients discharged with non-valvular AF in Denmark (n=132,372). For every patient, the risk of stroke and bleeding was calculated by CHADS₂, CHA₂DS₂-VASc, ...

    Also Ranks for: Vka Patients |  atrial fibrillation |  risk thromboembolism |  net clinical benefit |  nationwide cohort study
    KOL Index score: 14759

    OBJECTIVE: The purpose of this study was to determine the impact of symptoms of depression and anxiety on mortality and quality of life in patients hospitalized for acute myocardial infarction (MI).

    METHODS: The Beck Depression Inventory and the State-Trait Anxiety Inventory were completed by 288 patients hospitalized for MI. Twelve-month survival status was ascertained, and quality of life among survivors was assessed at 12 months using the Dartmouth COOP charts.

    RESULTS: Thirty-one ...

    Also Ranks for: 12 Months |  depression anxiety |  myocardial infarction |  quality life |  cardiac mortality
    KOL Index score: 14733

    OBJECTIVES: The purpose of this study was to investigate predictors of bleeding in a cohort of anticoagulated patients and to evaluate the predictive value of several bleeding risk stratification schemas.

    BACKGROUND: The risk of bleeding during antithrombotic therapy in patients with atrial fibrillation (AF) is not homogeneous, and several clinical risk factors have been incorporated into clinical bleeding risk stratification schemas. Current risk stratification schemas for bleeding ...

    Also Ranks for: Bleeding Risk |  atrial fibrillation |  anticoagulated patients |  labile inr |  liver function


    Deirdre Anne Lane: Influence Statistics

    Sample of concepts for which Deirdre Anne Lane is among the top experts in the world.
    Concept World rank
    independent blind reviewers #1
    adjusted prognostic association #1
    stroke european society #1
    cluster 95ci #1
    cardiac complications stroke #1
    diagnosed ischemic #1
    fibrillation attitude #1
    operational challenges mhealth #1
    patients persuasive interventions #1
    centres llpms #1
    systematic review metaregression #1
    pharmacist implementation #1
    postmi patients sex #1
    statement mhealth #1
    usual depression scores #1
    ttr data #1
    rehospitalization incident stroke #1
    medical telemedicine arrhythmias #1
    app characteristics #1
    interventions anticoagulation #1
    treat intervention #1
    11 947 patients #1
    apps functionality usability #1
    define evidence #1
    difference rhythm control #1
    experiences oac prescription #1
    ehra systematic review #1
    587 participants #1
    literature mhealth apps #1
    stroke lower odds #1
    cbt patients controls #1
    decision conflict usual #1
    anxiety md #1
    outcomes european patients #1
    holter current status #1
    usability app characteristics #1
    association medical prognosis #1
    rcts appbased interventions #1
    vte long term #1
    physicians patients experiences #1
    abc criteria studies #1
    fibrillation frail #1
    improvements oac prescription #1
    perspective ipa #1
    multidrug regime #1
    education ttr #1
    6673 patients #1
    prognosis disease severity #1
    manual pulse measurement #1
    2021 ishne #1

    Key People For Atrial Fibrillation

    Top KOLs in the world
    Gregory Yoke Hong Lip
    atrial fibrillation heart failure stroke prevention
    John Camm MD John Camm
    atrial fibrillation myocardial infarction heart rate
    Emelia J Benjamin
    atrial fibrillation framingham heart study heart failure
    Harry J G M C Crijns
    atrial fibrillation heart failure sinus rhythm
    Isabelle C Van Gelder
    atrial fibrillation heart failure rate control
    Stefan Hans Hohnloser
    atrial fibrillation myocardial infarction sinus rhythm

    Deirdre Anne Lane:Expert Impact

    Concepts for whichDeirdre Anne Lanehas direct influence:Atrial fibrillation,  Patients atrial fibrillation,  Stroke prevention,  Bleeding risk,  Heart failure,  Stroke risk,  Myocardial infarction,  Risk stroke.

    Deirdre Anne Lane:KOL impact

    Concepts related to the work of other authors for whichfor which Deirdre Anne Lane has influence:Atrial fibrillation,  Heart failure,  Oral anticoagulants,  Ischemic stroke,  Major bleeding,  Catheter ablation,  Myocardial infarction.



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    Department of Clinical Medicine, Aalborg University, 9000 Aalborg, Denmark | Department of Clinical Medicine Aalborg University Aalborg Denmark | Liverpool Centre for Cardiovascular Science, University of Liverpool and Liverpool Heart & Chest Hospita