• atrial fibrillation

    Prominent publications by Gregory I Chlouverakis

    KOL Index score: 13201

    Oral anticoagulation prevents ischemic strokes in patients with atrial fibrillation (AF). Early detection of AF and subsequent initiation of oral anticoagulation help to prevent strokes in AF patients. Implanted cardiac pacemakers and defibrillators allow seamless detection of atrial high rate episodes (AHRE), but the best antithrombotic therapy in patients with AHRE is not known.

    RATIONALE: Stroke risk is higher in pacemaker patients with AHRE than in those without, but the available ...

    Also Ranks for: Oral Anticoagulation |  patients ahre |  rate episodes |  stroke risk |  antithrombotic therapy
    KOL Index score: 11990

    BACKGROUND: Significant left main coronary artery stenosis is an accepted indication for surgical revascularization. The potential of angiography to evaluate the hemodynamic severity of a stenosis is limited. The aims of the present study were to assess the long-term clinical outcome of patients with an angiographically equivocal left main coronary artery stenosis in whom the revascularization strategy was based on fractional flow reserve (FFR) and to determine the relationship between ...

    Also Ranks for: Artery Stenosis |  ffr patients |  fractional flow reserve |  guided treatment |  coronary angiography
    KOL Index score: 10370

    OBJECTIVES: The purpose of this study was to investigate the efficacy and safety of amiodarone and propafenone in the conversion of chronic atrial fibrillation in a prospective, randomized, placebo-controlled study.

    BACKGROUND: The effectiveness of amiodarone and propafenone in the treatment of patients with chronic atrial fibrillation has not been adequately studied.

    METHODS: One hundred one patients (48 men, mean age 64 +/- 9 years) with atrial fibrillation lasting >3 weeks ...

    Also Ranks for: Chronic Atrial Fibrillation |  amiodarone propafenone |  3 weeks |  sinus rhythm |  1 week
    KOL Index score: 10364

    OBJECTIVES: We investigated whether the serum markers of collagen turnover differed in various forms of atrial fibrillation (AF) and in sinus rhythm (SR) in humans.

    BACKGROUND: Structural alterations and fibrosis have been implicated in the generation and perpetuation of AF.

    METHODS: Serum C-terminal propeptide of collagen type-I (CICP), C-terminal telopeptide of collagen type-I (CITP), matrix metalloproteinase-1, and tissue inhibitor of matrix metalloproteinases-1 were measured as ...

    Also Ranks for: Collagen Type |  extracellular matrix |  atrial fibrillation |  paroxysmal patients |  tissue inhibitor
    KOL Index score: 10331

    The appropriate treatment for the restoration of sinus rhythm in patients with atrial fibrillation (AF) of recent onset is still the subject of controversy. In this prospective, randomized, single-blind, placebo-controlled clinical study, we investigated the effectiveness and safety of procainamide, propafenone, and amiodarone, administered intravenously, for the conversion of recent-onset AF. We enrolled 362 consecutive patients (183 men; age 34 to 86 years; mean 65+/-10) with AF ...

    Also Ranks for: Onset Atrial |  amiodarone propafenone |  sinus rhythm |  hours patients |  successful conversion
    KOL Index score: 9574

    To assess the variability of head-up tilt table testing, 35 patients with vasovagal syncope, shown by a positive tilt table test, underwent a second test 1 week later. Also, on the day before each test, spectral and time-domain indexes of heart rate variability were derived from Holter recordings to examine the stability of autonomous nervous system activity in these patients. Fifteen healthy volunteers served as a control group and also underwent two tilt table tests with prior Holter ...

    Also Ranks for: Vasovagal Syncope |  table test |  autonomic nervous |  heart rate |  positive tilt
    KOL Index score: 9308

    STUDY OBJECTIVES: To investigate the efficacy and safety of amiodarone administered as the drug of first choice in the conversion of atrial fibrillation, regardless of its duration.

    DESIGN: : Prospective, randomized, controlled clinical study.

    SETTING: : Tertiary cardiac referral center.

    PATIENTS: Two-hundred eight consecutive patients (102 men; mean [+/- SD] age, 65 +/- 10 years) with atrial fibrillation.

    INTERVENTIONS: One-hundred eight patients received amiodarone, and 100 patients ...

    Also Ranks for: Sinus Rhythm |  atrial fibrillation |  patients amiodarone |  choice drug |  1 week
    KOL Index score: 9151

    AIM: To examine tumour samples immunohistochemically for MUC1 (episialin), epidermal growth factor receptor (EGFR), and c-erbB-2, since the disruption of the cell-cell adhesion system by MUC1 and the c-erbB oncoprotein family is known to be important in the development of metastasis in human cancers.

    METHODS: 93 tumour samples from patients with early stage non-small cell lung cancer treated with surgery alone were examined for episialin, EGFR, and c-erbB-2.

    RESULTS: Episialin ...

    Also Ranks for: Cell Lung |  poor survival |  erbb2 expression |  muc1 episialin |  human cancers
    KOL Index score: 9025

    BACKGROUND: Vascular endothelial cell growth factor (VEGF) acts by phosphorylating specific tyrosine kinase receptors on endothelial cell membrane promoting angiogenesis. The study of the activation status of VEGF receptors in human malignancies has recently become feasible by means of specific monoclonal antibodies recognising the phosphorylated form of these receptors.

    MATERIALS AND METHODS: In the current study, we investigate the expression of the phosphorylated VEGFR2/KDR receptor ...

    Also Ranks for: Colorectal Cancer |  tumour cells |  vegf receptors |  factor vascular |  endothelial growth
    KOL Index score: 9021

    OBJECTIVES: We investigated prospectively whether serum markers of collagen turnover could be used as predictors for the occurrence of malignant ventricular arrhythmias in patients with nonischemic dilated cardiomyopathy (NIDC) who had received an implantable cardioverter-defibrillator (ICD) for primary prevention.

    BACKGROUND: Extracellular matrix alterations in NIDC might provide electrical heterogeneity, thus potentially contributing to the occurrence of ventricular arrhythmia and ...

    Also Ranks for: Serum Markers |  dilated cardiomyopathy |  collagen turnover |  patients icd |  primary prevention
    KOL Index score: 8731

    BACKGROUND: The role of atrial overdrive pacing (AOP) in sleep apnea remains uncertain. We prospectively evaluated the effect of AOP after 24 hours and after one month in patients with the obstructive sleep apnea-hypopnea syndrome and compared it with the use of nasal continuous positive airway pressure (n-CPAP).

    METHODS: We studied 16 patients with a moderate or severe case of the obstructive sleep apnea-hypopnea syndrome (baseline mean apnea-hypopnea index, 49) and normal left ...

    Also Ranks for: Sleep Apnea |  atrial overdrive pacing |  heart rate |  airway pressure |  continuous positive
    KOL Index score: 8653

    BACKGROUND: Autonomic function in inflammatory bowel disease has not yet been studied by means of analysis of 24-hour heart rate variability.

    AIM: To measure heart rate variability in inflammatory bowel disease patients in remission.

    PATIENTS AND METHODS: Study population comprised 27 patients with inflammatory bowel disease in remission and 28 healthy, sex- and age-matched controls. Two frequency ranges were analysed: low frequency (0.06-0.15 Hz) and high frequency (0.15-0.40 ...

    Also Ranks for: Inflammatory Bowel Disease |  heart rate variability |  autonomic imbalance |  spectral analysis |  controls frequency
    KOL Index score: 8583

    The efficacy and safety of intravenous procainamide in the conversion of atrial fibrillation was investigated. A total of 114 patients without severe heart failure were randomized to receive either intravenous procainamide (1 g over 30 minutes, followed by an infusion of 2 mg/min over 1 hour) or placebo in a double-blind trial. Digoxin (0.5 mg intravenously) was administered to all patients who had not previously been receiving digoxin. Treatment was considered successful if sinus rhythm ...

    Also Ranks for: Atrial Fibrillation |  sinus rhythm |  intravenous procainamide |  humans hypotension |  efficacy safety
    KOL Index score: 8431

    The aim of this study was to examine whether the indexes of heart rate variability (HRV) are stable from day-to-day in patients with vasovagal syncope and whether the stability of the HRV indexes is linked with that of the clinical results of the tilt test. Nineteen patients with a history of syncopal episodes and a positive tilt test underwent a second test 1 week later. Of these, 11 (group P-P) also had a positive second test, whereas 8 (group P-N) had a negative second test. Fifteen ...

    Also Ranks for: Vasovagal Syncope |  heart rate variability |  tilt test |  syncopal patients |  domain indexes
    KOL Index score: 8240

    OBJECTIVES: Although recent studies suggest that inflammation is involved in the pathogenesis of atrial fibrillation (AF), it remains controversial whether it is a consequence or a cause of the arrhythmia.

    DESIGN: Prospective study.

    SETTING: Tertiary referral centre.

    PATIENTS AND INTERVENTIONS: In 52 patients with persistent AF lasting >3 months, high-sensitivity C-reactive protein (hs-CRP) was measured before and after electrical cardioversion.

    MEASUREMENTS AND RESULTS: All patients ...

    Also Ranks for: Atrial Fibrillation |  patients recurrence |  crp levels |  sinus rhythm |  electrical cardioversion


    Gregory I Chlouverakis: Influence Statistics

    Sample of concepts for which Gregory I Chlouverakis is among the top experts in the world.
    Concept World rank
    pride children #1
    cases gait variability #1
    preoperative measurements surgery #1
    coronary stenosis stress #1
    preoperative gait variability #1
    postoperative measurements surgery #1
    surgery postoperative measurements #1
    surgery preoperative measurements #1
    spectral differential entropy #1
    postoperative progression hypothesis #1
    postoperative gait variability #1
    voiss vhi #1
    gait variability measurements #1
    aop pacing #2
    gait variability pain #2
    episodes ≤24 hours #2
    backup atrial pacing #2
    apneahypopnea month #2
    syndrome aop #2
    anastomotic stenoses #2
    acute acl deficiency #2
    stable cad effects #2
    aop sleep apnea #2
    patients clinical episode #2
    flow reserve cfr #2
    oxidative stress stent #2
    hapv rapv #2
    operative gait #2
    types vasovagal syndrome #2
    recurrence symptomatic episode #2
    recurrence profile #2
    gedem orthopaedic tool #2
    data gedem #2
    levels bms #2
    stress stent implantation #2
    orthopaedic tool #2
    hypopnea month #2
    ilrs recurrence profile #2
    amiodarone 100 patients #2
    month aop #2
    ses metal stents #2
    recentonset amiodarone #2
    month apneahypopnea #2

    Key People For Atrial Fibrillation

    Top KOLs in the world
    Gregory Yoke Hong Lip
    atrial fibrillation heart failure stroke prevention
    John Camm MD John Camm
    atrial fibrillation myocardial infarction heart rate
    Emelia J Benjamin
    atrial fibrillation framingham heart study heart failure
    Harry J G M C Crijns
    atrial fibrillation heart failure sinus rhythm
    Isabelle C Van Gelder
    atrial fibrillation heart failure rate control
    Stefan Hans Hohnloser
    atrial fibrillation myocardial infarction sinus rhythm

    Gregory I Chlouverakis:Expert Impact

    Concepts for whichGregory I Chlouverakishas direct influence:Atrial fibrillation,  Vasovagal syncope,  Hypertensive patients,  Sinus rhythm,  Gait variability,  Peripheral monocytes,  Heart rate variability,  Oral anticoagulation.

    Gregory I Chlouverakis:KOL impact

    Concepts related to the work of other authors for whichfor which Gregory I Chlouverakis has influence:Atrial fibrillation,  Heart failure,  Sinus rhythm,  Coronary artery,  Fractional flow reserve,  Sleep apnea,  Catheter ablation.



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    Division of Biostatisctics, School of Medicine, University of Crete, Heraklion, Greece | Department of Social Medicine, Biostatistics Lab, School of Medicine, University of Crete, Voutes Place, 71500, Heraklion, Crete, Greece. | Department of Social