 | ShaoLiang ChenNanjing Medical University - Department of Cardiology | Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu 210006, P.R. China. ... |
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ShaoLiang Chen:Expert Impact
Concepts for whichShaoLiang Chenhas direct influence:Bifurcation lesions,Coronary intervention,Bronchopleural fistula,Percutaneous coronary,Acs patients,Intravascular ultrasound,Osa patients,Patients osa.
ShaoLiang Chen:KOL impact
Concepts related to the work of other authors for whichfor which ShaoLiang Chen has influence:Obstructive sleep apnea,Coronary artery disease,Osa patients,Cardiovascular outcomes,Sleep apnoea,Cpap adherence,Carbon nanomaterials.
KOL Resume for ShaoLiang Chen
| Year | |
|---|---|
| 2022 | Nanjing Medical University - Department of Cardiology |
| 2021 | Division of Cardiology, Nanjing first hospital, Nanjing medical unviersity, China. Electronic address: |
| 2016 | From Department of Cardiology, National University Heart Centre, Singapore (C-H.L., G.L., C.-Y.K., P.-F.C., M.Y.C., A.M.R., H.-C.T.); Department of Cardiology, King George's Medical University, Lucknow, India (R.S., S.C., A.M., R.B.K.); Department of Cardiology, Shanghai Chest Hospital, China (R.L., X.-X.Y., W.-W.Z.); Department of Cardiology, Tan Tock Seng Hospital, Singapore (H.-H.H.); No (1) 1000-Bed Defence Services General Hospital, Mingaladon, Yangon, Myanmar (T.H.); Cardiac Medical Unit, Grantham Hospital, Hong Kong (M.-H.J.); Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, China (X.-F.G., Z.G., S.-L.C., J.-J.Z.); Hypertension Unit-Heart Institute (InCor), University of Sao Paulo Medical School, Brazil (S.F.F., C.H.G.U., L.F.D.); Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore (T.-H.O.); Sleep Educators, Antioch, CA (G.R.); and Saw Swee Hock School of Public Health, National University of Singapore, Singapore (B.-C.T.). Dipartimento di Scienze Mediche, Divisione di Cardiologia, Città della Salute e della Scienza, Turin, Italy |
| 2013 | Division of Plastic Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan |
| 2007 | Zhong-Shan Hospital, Fudan University, Shanghai 200032, China |
| 2005 | Fudan-Pharmco Targeting Drug Research Center, Department of Pharmaceutics, School of Pharmacy, University of Fudan, Shanghai, 200032, China, and Department of Nuclear Medicine, Zhongshan Hospital, Shanghai, China |
| Concept | World rank |
|---|---|
| macces osa | #14 |
| polyhydroxylated derivative | #23 |
| eluting microporous | #24 |
| microporous stent | #25 |
| c60ohx | #68 |
Prominent publications by ShaoLiang Chen
Obstructive Sleep Apnea and Cardiovascular Events After Percutaneous Coronary Intervention
[ PUBLICATION ]
BACKGROUND: There is a paucity of data from large cohort studies examining the prognostic significance of obstructive sleep apnea (OSA) in patients with coronary artery disease. We hypothesized that OSA predicts subsequent major adverse cardiac and cerebrovascular events (MACCEs) in patients undergoing percutaneous coronary intervention.
METHODS AND RESULTS: The Sleep and Stent Study was a prospective, multicenter registry of patients successfully treated with percutaneous coronary ...
| Known for Percutaneous Coronary | Cardiovascular Events | Osa Patients | Obstructive Sleep Apnea | Sleep Study |
Mesenteric artery remodeling and effects of imidapril and irbesartan on it in spontaneously hypertensive rats
[ PUBLICATION ]
AIM: To investigate the remodeling of mesenteric artery and the expression of TGF-beta1, c-Jun in mesenteric artery and effects of imidapril and irbesartan on the remodeling in spontaneously hypertensive rats (SHR).
METHODS: Thirty SHR (male/female, 21/9), aged 13 wk, were randomly divided into 3 groups (7 male rats and 3 female rats each group): SHR group, imidapril group (imidapril 3 mg/kg.d was given in drinking water for 14 wk), and irbesartan group (irbesartan 50 mg/kg.d was given ...
| Known for Shr Wky | Hypertensive Rats | Transforming Growth | Beta1 Angiotensin | Converting Enzyme |
AIMS: There is uncertainty on which stenting approach confers the best long-term outlook for unprotected left main (ULM) bifurcation disease.
METHODS AND RESULTS: This is a non-randomized, retrospective study including all consecutive patients with 50% stenosis of the left main involving at least 1 of the arteries stemming from the left main treated with drug-eluting stents (DES) in 9 European centers between 2002 and 2004. Patients were divided into two groups: those treated with ...
| Known for Coronary Artery | Provisional Stenting | Stent Strategy | Target Lesion Revascularization | Cardiovascular Death |
(99m)Technetium-labeled diethylenetriamine pentaacetic acid-polyethylene glycol-folate (DTPA-PEG-folate) was synthesized and tested as a radiopharmaceutical agent, which targeted the lymphatic system with metastatic tumor. Folic acid was reacted with H2N-PEG-NH2 to yield H2N-PEG-folate. After purification by anion-exchange chromatography, the product was reacted with cyclic DTPA. By removal of unreacted DTPA by size-exclusion chromatography, DTPA-PEG-Folate was obtained. ...
| Known for Folic Acid | Biological Evaluation | Polyethylene Glycols | Subcutaneous Injection | Cell Uptake |
Biodistribution of 99mTc-C60(OH)x in Sprague–Dawley rats after intratracheal instillation
[ PUBLICATION ]
An increasing number of studies have been devoted to studying the respiratory toxicity of carbon nanomaterials, but little information is known, thus far, on the biodistribution of these nanomaterials after inhalation or intratracheal instillation. We synthesized and labeled a polyhydroxylated derivative of fullerene C60(OH)x (x=22,24) with 99mTc. With single photon emission computed tomography imaging and 〈gamma〉-ray counting techniques, the biodistribution of 99mTc-C60(OH)x in ...
| Known for Intratracheal Instillation | Carbon Nanomaterials | Dawley Rats | Fast Clearance | Highest Retention |
Treatment of Empyema and Bronchopleural Fistula by Bovine Pericardium and Latissimus Flap
[ PUBLICATION ]
Management of empyema with bronchopleural fistula remains a challenge. A 38-year-old man who had bullous emphysema was hospitalized on account of a right-sided necrotizing pneumonia complicated by empyema that mandated a tube drainage. Persistent air leak from the chest tube was noted, and chest computed tomography confirmed an empyema cavity with a suspicious bronchopleural fistula. This complex condition was successfully treated using fibrin glue with buttressed bovine pericardium to ...
| Known for Bronchopleural Fistula | Pleural Diseases | Muscle Flap | Air Leak | Necrotizing Pneumonia |
BACKGROUND: Current guidelines recommend administering dual antiplatelet therapy (DAPT) for 12 months to patients with acute coronary syndromes (ACS) and without contraindications after drug-eluting stent (DES) implantation. A recent study reported that 3 months of DAPT followed by ticagrelor monotherapy is effective and safe in ACS patients undergoing DES implantation compared with the standard duration of DAPT. However, it is unclear whether antiplatelet monotherapy with ticagrelor ...
| Known for Pci Patients | Acute Coronary | Ivus Guided | Macce 1 | Major Adverse |
Ticagrelor With or Without Aspirin in Chinese Patients Undergoing Percutaneous Coronary Intervention: A TWILIGHT China Substudy
[ PUBLICATION ]
BACKGROUND: The risk/benefit tradeoff of dual antiplatelet therapy after percutaneous coronary intervention may vary in East Asian patients as compared with their non-East Asian counterparts.
METHODS: The double-blind, placebo-controlled, randomized TWILIGHT trial (Ticagrelor With Aspirin or Alone in High-Risk Patients After Coronary Intervention) enrolled patients undergoing high-risk percutaneous coronary intervention. After 3 months of treatment with ticagrelor plus aspirin, ...
| Known for Undergoing Percutaneous | Coronary Intervention | Dual Antiplatelet Therapy | Events Compared |
The vessel wall is an intricate structure composed of three layers: the intima (consisting of endothelial cells), media (consisting of smooth muscle cells and elastic fibers), and externa (consisting of the extracellular matrix scaffold). The homeostasis of the vasculature depends on the consistent function of each layer. In the vascular system, potassium channels are well known to regulate vascular function. The interactions between vascular conditions and membrane potential are ...
| Known for Potassium Channels |
