• Disease
  • Bile
  • Bile Duct
  • Shigehiko Shionoya

    Prominent publications by Shigehiko Shionoya

    KOL Index score: 11630

    From 1979 through 1989, surgical resection was performed in 55 of 66 patients with carcinoma of the hepatic hilus after improving jaundice by percutaneous transhepatic biliary drainage (PTBD). Selective cholangiography through PTBD was done to define precisely the anatomical location—extent of the obstructing lesion in each segmental hepatic duct. Percutaneous transhepatic cholangioscopy was performed through the sinus tract of PTBD after replacing the drainage catheter with a 15 French ...

    Also Ranks for: Hepatic Hilus |  lobe resection |  bile duct |  female hepatectomy humans |  66 patients
    KOL Index score: 10182

    To elucidate the clinical significance of perineural invasion on bile duct cancer, a clinicopathologic study was performed on 70 resected patients with bile duct carcinoma. The overall incidence of perineural invasion in the resected specimen was 81.4%. There seemed to be no correlation between perineural invasion and site, size of the tumor, and lymph node metastasis. A significant correlation was observed, however, between macroscopic type, microscopic type, depth of invasion, and ...

    Also Ranks for: Perineural Invasion |  bile duct |  nerve fibers |  common humans |  aged neoplasm
    KOL Index score: 9339

    In order to discover the effect of external biliary drainage on liver regeneration, we have produced a model system carrying cannula in the common bile duct of rat liver and examined the regeneration capacity of liver after partial hepatectomy under various conditions. Previously we have shown that hepatic cells proliferate by obstructive jaundice alone without partial hepatectomy [Terasaki et al; Jpn J Cancer Res 1991;82:170-175]. In the present study, we showed that DNA ...

    Also Ranks for: External Biliary Drainage |  regeneration capacity |  rat liver |  obstructive jaundice |  partial hepatectomy
    KOL Index score: 7892

    Twenty-nine patients with advanced carcinoma of the bile duct or gallbladder underwent combined portal vein and liver resection. Segmental excision of the portal vein was performed in 16 cases and wedge resection of the vessel wall in 13. The operative mortality rate was 17 per cent. The median survival for the 24 patients who left hospital was 19.8 months. Actuarial survival rates at 1, 3 and 5 years for all 29 patients were 48 per cent, 29 per cent, and 6 per cent respectively, whereas ...

    Also Ranks for: Liver Resection |  biliary tract |  portal vein |  advanced carcinoma |  bile duct
    KOL Index score: 6906

    Sphincter of Oddi motility was measured in 55 gallstone patients either through the sinus tract of percutaneous transhepatic biliary drainage or through the T tube. The influence of cholecystectomy and gastrectomy on the sphincter of Oddi was analyzed by comparing responses in patients with or without surgery to the administration of cerulein and the ingestion of dry egg yolk. When comparing cholecystectomized patients to nonsurgical subjects, cholecystectomy revealed no influence on the ...

    Also Ranks for: Sphincter Oddi |  contraction waves |  paradoxical response |  egg yolk |  gastrectomy humans
    KOL Index score: 6639

    Since July 1975, percutaneous transhepatic biliary drainage (PTBD) has been performed in 533 cases, and since April 1977 we have developed percutaneous transhepatic cholangioscopy (PTCS) as a diagnostic and therapeutic endoscopical tool in 198 cases of malignant disease and 195 benign cases. After dilating the sinus tract of PTBD using a 15-Fr catheter about 2 weeks after PTBD, PTCS was carried out through the sinus tract. PTCS has diagnostic advantages: the lesion can be accurately ...

    Also Ranks for: Percutaneous Transhepatic |  biliary tract |  ptbd ptcs |  biopsy specimens |  malignant disease
    KOL Index score: 6341

    This study, using C3a, C4a, and C5a assay and crossed immunoelectrophoresis in vitro and in vivo, was designed to determine whether vascular prostheses activate the complement system. The degree of complement activation and the pathway of activation were also studied. The complement levels (C3, C4, CH50) in different arterial diseases were measured, and the relationship of complement levels to serum lipids in patients with arteriosclerosis obliterans (ASO) was also investigated, in order ...

    Also Ranks for: Complement Activation |  vascular prostheses |  c4 levels |  classical humans |  vessel prosthesis
    KOL Index score: 6236

    Using a percutaneous transhepatic cholangioscopy (PTCS) catheter, sphincter of Oddi motility was measured in a patient with papillary stenosis secondary to bile duct stones. Prior to sphincterotomy, intramuscular injection of 20 μg caerulein did not inhibit pathological contraction waves of the sphincter of Oddi or relieve abdominal pain. Endoscopic sphincterotomy of the lower segment of the sphincter of Oddi resulted in recovery of the normal response to caerulein, i.e. relaxation of ...

    Also Ranks for: Sphincter Oddi |  bile duct |  humans manometry |  percutaneous transhepatic |  contraction waves
    KOL Index score: 5980

    The clinical course of 328 patients with Buerger's disease (thromboangiitis obliterans: TAO) was followed. Neither ischaemic ulcers nor gangrene occurred in 26 per cent of the patients. Almost all of the ulcers occurred in patients between 20 and 50 years of age, with a peak incidence between 40 and 45 years. The younger the patient at the onset of the disease, the later the first ulcer occurred, and the later the first ulcer occurred, the shorter the period in which ulceration may ...

    Also Ranks for: Patients Tao |  major amputation |  progression symptoms |  thromboangiitis obliterans |  buergers disease
    KOL Index score: 5826

    After many changes, Buerger's disease stands as an independent clinicopathologic entity, but a better understanding of Buerger's disease has been impeded by the lack of unanimous diagnostic criteria of the disease. Since specificity of Buerger's disease is characterized by peripheral ischemia of an inflammatory nature and with a self-limiting course, diagnostic criteria of Buerger's disease should be discussed from clinical point of view. Our clinical criteria for the diagnosis of ...

    Also Ranks for: Buergers Disease |  clinical criteria |  50 years |  phlebitis migrans |  diagnosis buerger
    KOL Index score: 5525

    This article reports a case of an infrarenal abdominal aortic aneurysm complicated with chronic disseminated intravascular coagulopathy (DIC). The patient was a 68-year-old man; bleeding of 20 months' duration was reported. Physical examination indicated a pulsating mass in the abdomen. The diagnosis of DIC was made on the basis of standard coagulation studies. Indium 111-labeled platelet scintigraphy demonstrated an increased accumulation of radioactivity over the aneurysm. After ...

    Also Ranks for: Abdominal Aortic Aneurysm |  disseminated intravascular |  surgical treatment |  gabexate mesilate |  bleeding tendency


    Shigehiko Shionoya: Influence Statistics

    Sample of concepts for which Shigehiko Shionoya is among the top experts in the world.
    Concept World rank
    primary lesion arm #1
    young mongrel dogs #1
    arthus reaction role #1
    takayasukrankheit arthus #1
    ulcer occurred #1
    toes limbs #1
    microcirculation foot humans #1
    urinary cotinine measurement #1
    surgical therapy hypertension #1
    lumbar sympathectomy microcirculation #1
    buergers disease hospital #1
    arteriitis aortic #1
    9 extremities #1
    vascular lesions influences #1
    vasorum vena cava #1
    bradykinin microcirculation #1
    cystic degeneration media #1
    treatment buergers disease #1
    blood pressures foot #1
    theaorta renovascular lesions #1
    dysplasia abdominal #1
    direct arterial surgery #1
    vasa vasorum extension #1
    blunt injury hand #1
    thrombus progress #1
    atypical coarctation theaorta #1
    infections vasa #1
    unanimous diagnostic criteria #1
    bypass 22 thromboendarterectomy #1
    type leg #1
    23 148 patients #1
    97 106 limbs #1
    vascular buerger #1
    50 creatinine #1
    toes gangrene #1
    ulcer thromboangiitis #1
    early failure api #1
    tpi api #1
    wall concerned #1
    microcirculation tao #1
    hypertension chirurgische #1
    tpi blood #1
    obliterans tao #1
    buergers disease requirements #1
    adventitia “periarteritis nodosa #1
    operation degeneration #1

    Key People For Bile Duct

    Top KOLs in the world
    Yuji Nimura
    bile duct portal vein hilar cholangiocarcinoma
    Yasuni Nakanuma
    primary biliary cirrhosis bile duct hepatocellular carcinoma
    John L Cameron†
    pancreatic cancer acute pancreatitis surgical resection
    Peter B Cotton
    chronic pancreatitis oddi dysfunction pancreas divisum
    Leslie Harold Blumgart
    hepatic resection colorectal cancer bile duct
    Henry Anthony Pitt
    acute cholangitis tokyo guidelines pancreatic cancer

    Shigehiko Shionoya:Expert Impact

    Concepts for whichShigehiko Shionoyahas direct influence:Bile duct,  Hepatic hilus,  Abdominal aortic aneurysm,  Vasa vasorum,  Hepatic artery,  Bile duct carcinoma,  Buergers disease,  Intermittent claudication.

    Shigehiko Shionoya:KOL impact

    Concepts related to the work of other authors for whichfor which Shigehiko Shionoya has influence:Hilar cholangiocarcinoma,  Thromboangiitis obliterans,  Bile duct,  Buerger disease,  Gallbladder cancer,  Vasa vasorum,  Caudate lobe.



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    First Department of Surgery, Nagoya University, Tsurumai‐cho 65, Syowa‐ku, Nagoya, Japan | Department of Surgery, Nagoya University Branch Hospital, Nagoya, Japan | Department of Surgery, Nagoya University Branch Hospital, Japan | First Department of