 | Georgios Petrides |
Prominent publications by Georgios Petrides
Right Unilateral Ultrabrief Pulse ECT in Geriatric Depression: Phase 1 of the PRIDE Study
[ PUBLICATION ]
OBJECTIVE: The Prolonging Remission in Depressed Elderly (PRIDE) study evaluated the efficacy of right unilateral ultrabrief pulse electroconvulsive therapy (ECT) combined with venlafaxine for the treatment of geriatric depression.
METHOD: PRIDE was a two-phase multisite study. Phase 1 was an acute course of right unilateral ultrabrief pulse ECT, combined with open-label venlafaxine at seven academic medical centers. In phase 2 (reported separately), patients who had remitted were ...
| Also Ranks for: Pride Study | geriatric depression | ultrabrief pulse | antidepressive agents | phase 1 |
Bifrontal, bitemporal and right unilateral electrode placement in ECT: randomised trial
[ PUBLICATION ]
BACKGROUND: Electroconvulsive therapy (ECT) is an effective treatment for major depression. Optimising efficacy and minimising cognitive impairment are goals of ongoing technical refinements.
AIMS: To compare the efficacy and cognitive effects of a novel electrode placement, bifrontal, with two standard electrode placements, bitemporal and right unilateral in ECT.
METHOD: This multicentre randomised, double-blind, controlled trial (NCT00069407) was carried out from 2001 to 2006. A total ...
| Also Ranks for: Electrode Placement | bifrontal bitemporal | seizure threshold | major depression | ect effective treatment |
Electroconvulsive Therapy Augmentation in Clozapine-Resistant Schizophrenia: A Prospective, Randomized Study
[ PUBLICATION ]
OBJECTIVE: Up to 70% of patients with treatment-resistant schizophrenia do not respond to clozapine. Pharmacological augmentation to clozapine has been studied with unimpressive results. The authors examined the use of ECT as an augmentation to clozapine for treatment-refractory schizophrenia.
METHOD: In a randomized single-blind 8-week study, patients with clozapine-resistant schizophrenia were assigned to treatment as usual (clozapine group) or a course of bilateral ECT plus clozapine ...
| Also Ranks for: Clozapine Ect | therapy augmentation | resistant schizophrenia | 4 weeks | response criterion |
A Novel Strategy for Continuation ECT in Geriatric Depression: Phase 2 of the PRIDE Study
[ PUBLICATION ]
OBJECTIVE: The randomized phase (phase 2) of the Prolonging Remission in Depressed Elderly (PRIDE) study evaluated the efficacy and tolerability of continuation ECT plus medication compared with medication alone in depressed geriatric patients after a successful course of ECT (phase 1).
METHOD: PRIDE was a two-phase multisite study. Phase 1 was an acute course of right unilateral ultrabrief pulse ECT, augmented with venlafaxine. Phase 2 compared two randomized treatment arms: a ...
| Also Ranks for: Continuation Ect | pride study | geriatric depression | phase 2 | efficacy tolerability |
BACKGROUND: Although electroconvulsive therapy (ECT) has been shown to be extremely effective for the acute treatment of major depression, it has never been systematically assessed as a strategy for relapse prevention.
OBJECTIVE: To evaluate the comparative efficacy of continuation ECT (C-ECT) and the combination of lithium carbonate plus nortriptyline hydrochloride (C-Pharm) in the prevention of depressive relapse.
DESIGN: Multisite, randomized, parallel design, 6-month trial performed ...
| Also Ranks for: Major Depression | electroconvulsive therapy | relapse prevention | multisite study | continuation ect cect |
INTRODUCTION: Patients with Major Depressive Disorder (MDD) referred for electroconvulsive therapy (ECT) have poorer Health Related Quality of Life (HRQOL), compared with other patients with MDD, but ECT is associated with significant and durable improvement in HRQOL. However, no prior research has focused exclusively on elderly patients with MDD receiving ECT.
METHODS: HRQOL data from 240 depressed patients over the age of 60 was measured with the Medical Outcomes Study Short Form 36 ...
| Also Ranks for: Electroconvulsive Therapy | elderly depressed patients | health quality life | hrqol ect | major depressive disorder |
Data regarding the co-occurrence of anxiety symptoms or syndromes in schizophrenia is scant. Hierarchical assumptions embedded in diagnostic systems and methodologic difficulties hamper the development of studies on accessory symptomatology outside of the core positive-negative-disorganized symptoms. Recent studies have repeatedly challenged these assumptions by presenting data on comorbid disorders in schizophrenia. We review the current knowledge about anxiety comorbidity in ...
| Also Ranks for: Anxiety Disorders | schizophrenia data | computerized search | panic disorder | obsessive compulsive |
Learning from negative feedback in patients with major depressive disorder is attenuated by SSRI antidepressants
[ PUBLICATION ]
One barrier to interpreting past studies of cognition and major depressive disorder (MDD) has been the failure in many studies to adequately dissociate the effects of MDD from the potential cognitive side effects of selective serotonin reuptake inhibitors (SSRIs) use. To better understand how remediation of depressive symptoms affects cognitive function in MDD, we evaluated three groups of subjects: medication-naïve patients with MDD, medicated patients with MDD receiving the SSRI ...
| Also Ranks for: Negative Feedback | major depressive disorder | ssri antidepressants | mdd healthy subjects | learning positive |
The Combined Use of Electroconvulsive Therapy and Antipsychotics in Patients With Schizophrenia
[ PUBLICATION ]
OBJECTIVES: We sought to review the literature on the use of combined antipsychotic medications and electroconvulsive therapy (ECT) for the treatment of schizophrenia, with regard to efficacy, side effects, and ECT technique.
METHODS: A computerized search of the literature published from 1980 to 2004 was conducted on Medline and PsychoInfo using the words schizophrenia, antipsychotic, neuroleptic, psychotropic, and ECT. Only studies including patients with the diagnosis of schizophrenia ...
| Also Ranks for: Electroconvulsive Therapy | combination ect | patients schizophrenia | computerized search | antipsychotic agents |
ECT Remission Rates in Psychotic Versus Nonpsychotic Depressed Patients: A Report from CORE
[ PUBLICATION ]
OBJECTIVE: To compare the relative efficacy of electroconvulsive therapy (ECT) in psychotic and nonpsychotic patients with unipolar major depression.
METHODS: The outcome of an acute ECT course in 253 patients with nonpsychotic (n = 176) and psychotic (n = 77) unipolar major depression was assessed in the first phase of an ongoing National Institute of Mental Health-supported four-hospital collaborative study of continuation treatments after successful ECT courses. ECT was administered ...
| Also Ranks for: Remission Rate | depressed patients | nonpsychotic depression | disorders severity | acute ect |
Subcallosal cingulate deep brain stimulation for treatment-resistant depression: a multisite, randomised, sham-controlled trial
[ PUBLICATION ]
BACKGROUND: Deep brain stimulation (DBS) of the subcallosal cingulate white matter has shown promise as an intervention for patients with chronic, unremitting depression. To test the safety and efficacy of DBS for treatment-resistant depression, a prospective, randomised, sham-controlled trial was conducted.
METHODS: Participants with treatment-resistant depression were implanted with a DBS system targeting bilateral subcallosal cingulate white matter and randomised to 6 months of active ...
| Also Ranks for: Subcallosal Cingulate | deep brain stimulation | treatmentresistant depression | 6 months | controlled trial |
Case material and retrospective studies support the use of both lorazepam and ECT in treating catatonia, but few prospective investigations exist and none employ quantitative monitoring of response. In this study we test their efficacy in an open, prospective protocol, and define a "lorazepam test' with predictive value for treatment. Twenty-eight patients with catatonia were treated systematically with parenteral and/or oral lorazepam for up to 5 days, and with ECT if lorazepam failed. ...
| Also Ranks for: Lorazepam Ect | catatonia treatment | rating scale | catatonic symptoms | 21 patients |
PURPOSE OF REVIEW: ECT remains an important, yet underutilized, treatment for schizophrenia. Recent research shows that medication-resistant patients with schizophrenia, including those resistant to clozapine, respond well to ECT augmentation. The purpose of this article is to review recent studies of the use of ECT in the treatment of schizophrenia.
RECENT FINDINGS: We performed an electronic database search for articles on ECT and schizophrenia, published in 2017. The main themes of ...
| Also Ranks for: Ect Schizophrenia | growing evidence | therapy humans | antipsychotic agents | resistant patients |
Georgios Petrides: Influence Statistics
| Concept | World rank |
|---|---|
| dsmiv motor criteria | #1 |
| records inpatients | #1 |
| trial electroconvulsive | #1 |
| spearman nms | #1 |
| inpatients stringent criteria | #1 |
| catatonia prospective | #1 |
| disorder catatonic | #1 |
| catatonic signs scores | #1 |
| continuation ect | #1 |
| severity scores nms | #1 |
| 15 adolescents ect | #1 |
| multiple catatonic signs | #1 |
| ect clozapine | #1 |
| psychiatric treatment conclusions | #1 |
| illness catatonic | #1 |
| seizureshortening effects | #1 |
| ect lorazepam | #1 |
| age titration | #1 |
| transtornos psiquiátricos medline | #1 |
| nms spearman | #1 |
| simulatedect | #1 |
| 1271 sessions | #1 |
| dsmiv criteria nms | #1 |
| greece ect | #1 |
| nms lorazepam | #1 |
| switched propofol | #1 |
| continuation ect cect | #1 |
| catatonic schizophrenia catatonia | #1 |
| promise psychiatric treatment | #1 |
| fibrillation electroconvulsive | #1 |
| ect acute ect | #1 |
| long seizures patients | #1 |
| ketamine anesthesia ect | #1 |
| initial parenteral challenge | #1 |
| rating scale predictive | #1 |
| titration estimates | #1 |
| lorazepam response | #1 |
| somatic treatment psychiatry | #1 |
| dose titration method | #1 |
| halfage | #1 |
| 18 hospitals ect | #1 |
| adolescents general anesthetics | #1 |
| ect 28 patients | #1 |
| catatonic nms | #1 |
| seizures adolescents | #1 |
Key People For Electroconvulsive Therapy
Georgios Petrides:Expert Impact
Concepts for whichGeorgios Petrideshas direct influence:Electroconvulsive therapy, Electroconvulsive therapy ect, Bipolar disorder, Continuation ect, Pride study, Negative feedback, Rating scale, Major depression.
Georgios Petrides:KOL impact
Concepts related to the work of other authors for whichfor which Georgios Petrides has influence:Electroconvulsive therapy, Bipolar disorder, Deep brain stimulation, Major depression, Ect patients, Neuroleptic malignant syndrome, Suicidal ideation.
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