 | Jan Albert StaessenShow email addressResearch Institute Alliance for the Promotion of Preventive Medicine (APPREMED), Mechelen, Belgium | Research Institute Alliance for the Promotion of Preventive Medicine, ... |
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Jan Albert Staessen:Expert Impact
Concepts for whichJan Albert Staessenhas direct influence:Blood pressure,Systolic hypertension,Isolated systolic hypertension,Renal denervation,Ambulatory blood pressure,Arterial stiffness,Pulse pressure,Ambulatory blood.
Jan Albert Staessen:KOL impact
Concepts related to the work of other authors for whichfor which Jan Albert Staessen has influence:Blood pressure,Arterial stiffness,Cardiovascular disease,Heart failure,Hypertensive patients,Metabolic syndrome,Type 2 diabetes.
KOL Resume for Jan Albert Staessen
| Year | |
|---|---|
| 2022 | Research Institute Alliance for the Promotion of Preventive Medicine (APPREMED), Mechelen, Belgium |
| 2021 | NPA Alliance for the Promotion of Preventive Medicine (APPREMED), Mechelen, Belgium Research Institute Alliance for the Promotion of Preventive Medicine (J.A.S.) University of Leuven - Biomedical Sciences Group |
| 2020 | Studies Coordinating Centre Research Unit Hypertension and Cardiovascular Epidemiology KU Leuven Department of Cardiovascular Sciences University of Leuven Belgium Cardiovascular Research Institute MaastrichtMaastricht University Maastricht The Netherlands NPA Association for the Promotion of Preventive Medicine (J.A.S.). Division of Cardiology, University Hospital Zürich, Switzerland (S.T.). |
| 2019 | From Neuroscience Research Australia (R.P., K.J.A.); University of New South Wales (R.P., C.A., H.B., J.C., P.S.S., K.J.A.), Sydney, Australia; Johns Hopkins University (S.Y., M.C.C.), Baltimore, MD; The George Institute for Global Health (C.A., J.C.), Sydney, Australia; The George Institute China at Peking University Health Sciences Center (C.A.), Beijing, China; Icahn School of Medicine at Mount Sinai (S.A.), New York, NY; Center for Life Course Health Research/Geriatrics (R.A., S.K.-K., S.S., E.V.), University of Oulu; Medical Research Center Oulu (R.A.), Oulu University Hospital; Oulu City Hospital (R.A.), Finland; Department of Preventive Medicine and Public Health (H.A.), Fukuoka University, Japan; Guys and St Thomas' NHS Foundation Trust (N.B.), London, UK; University of Pittsburgh (J.C.B., M.G.), PA; Leiden University Medical Centre (A.S.B., S.T.), the Netherlands; University of Sheffield (A.B., J.P.), UK; School for Mental Health and Neuroscience, Department of Psychiatry and Neuropsychology (M.v.B., S.K.), Maastricht University, the Netherlands; University of Cambridge (C.B.), UK; University of California (M.C., C.K.), Irvine; University of Florida (S.D.), Gainesville; Albert Einstein College of Medicine (C.D., M.K.), New York, NY; University of Alberta (R.A.D., G.P.M.), Edmonton, Canada; International Longevity Centre (F.F.), Paris, France; University of Amsterdam (W.A.v.G., E.P.M.v.C.), the Netherlands; Golgi Cenci Foundation (A.G., R.V.), Milan, Italy; Trinity College Dublin (A.H., R.A.K.), Ireland; University of Calgary (D.B.H.), Canada; Newcastle University (C.J., B.C.M.S.), Newcastle upon Tyne; University of Bristol (P.G.K., S.K.K.), UK; University of Eastern Finland (J.L.), Kuopio; Faculty of Sport and Health Sciences, University of Jyväskylä (J.L.), Finland; School of Pharmacy, University of Waterloo (C.M.), Ontario, Canada; Academic Medical Center (T.v.M., E.R.), Amsterdam; Donders Institute for Brain, Cognition and Behaviour (T.v.M., E.R.), Radboud University Medical Center, Nijmegen, the Netherlands; National University of Singapore (T.-P.N.); Sengkang General Hospital (I.R.), Singhealth Duke-NUS Academic Medical Centre, Singapore; Dalhousie University (K.R.), Halifax, Canada; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy (L.R., I.S.), and Department of Psychology (J.S.), Centre for Ageing and Health (AgeCap) at the University of Gothenburg, Sweden; University of Leuven (J.A.S., L.T.), Belgium; Bordeaux Population Health Research Center (P.J.T., C.T.), UMR 1219, CHU Bordeaux, University of Bordeaux, Inserm, France; University of Adelaide (P.J.T.); Australian National University (E.W.), Canberra, Australia; and University of Warwick (J.W.), Coventry, UK. Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, The Netherlands (C.V., J.A.S.). Imperial College London, London, UK |
| Concept | World rank |
|---|---|
| 100 suburb | #1 |
| adrb1 arg389gly | #1 |
| pressure components | #1 |
| antihypertensive drugs diuretics | #1 |
| induced blood pressure | #1 |
| isolierte systolische | #1 |
| human sah | #1 |
| idhoco cardiovascular outcome | #1 |
| bcd hea | #1 |
| longitudinal lv indexes | #1 |
| blood pressure baseline | #1 |
| add1 cardiovascular prognosis | #1 |
| heart omics ageing | #1 |
| flemish population study | #1 |
| hypertension conventional | #1 |
| aceis arbs ccbs | #1 |
| bone resorption women | #1 |
| age psbp | #1 |
| rs11904439 | #1 |
| ambulatory hg | #1 |
| method trials | #1 |
| trial systolic | #1 |
| sizes doubling | #1 |
| pwv analyses | #1 |
| calciumchannel blockers reduction | #1 |
| p⩽00067 | #1 |
| elbw children years | #1 |
| hypertension 3681 participants | #1 |
| gaoyou population study | #1 |
| hypertension homozygotes | #1 |
| aip aic | #1 |
| dbp antihypertensive treatment | #1 |
| cardiac output ketanserin | #1 |
| rs2043013 | #1 |
| n821 | #1 |
| cancer cadmium | #1 |
| 101553 | #1 |
| blood pressure recurrence | #1 |
| 451 years | #1 |
| cardiovascular outcome idaco | #1 |
| 507 years | #1 |
| 546 years | #1 |
| impaired renal health | #1 |
| diastolic pressure whites | #1 |
| central caix paix | #1 |
| masked obp | #1 |
| mpap hstnt | #1 |
| general population electrolytes | #1 |
| variability cardiovascular disease | #1 |
| ucmgp vascular stiffness | #1 |
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Prominent publications by Jan Albert Staessen
BACKGROUND: Underweight, overweight, and obesity in childhood and adolescence are associated with adverse health consequences throughout the life-course. Our aim was to estimate worldwide trends in mean body-mass index (BMI) and a comprehensive set of BMI categories that cover underweight to obesity in children and adolescents, and to compare trends with those of adults.
METHODS: We pooled 2416 population-based studies with measurements of height and weight on 128·9 million participants ...
| Known for Worldwide Trends | Bmi Prevalence | Pooled Analysis | 1 2 | Boys Obesity |
BACKGROUND: Comparable global data on health and nutrition of school-aged children and adolescents are scarce. We aimed to estimate age trajectories and time trends in mean height and mean body-mass index (BMI), which measures weight gain beyond what is expected from height gain, for school-aged children and adolescents.
METHODS: For this pooled analysis, we used a database of cardiometabolic risk factors collated by the Non-Communicable Disease Risk Factor Collaboration. We applied a ...
| Known for Boys Girls | Children Adolescents | Bmi Height | Weight Gain | Mass Child |
BACKGROUND: Raised blood pressure is an important risk factor for cardiovascular diseases and chronic kidney disease. We estimated worldwide trends in mean systolic and mean diastolic blood pressure, and the prevalence of, and number of people with, raised blood pressure, defined as systolic blood pressure of 140 mm Hg or higher or diastolic blood pressure of 90 mm Hg or higher.
METHODS: For this analysis, we pooled national, subnational, or community population-based studies that had ...
| Known for Blood Pressure | Worldwide Trends | Pooled Analysis | South Asia | Subsaharan Africa |
Comparison of active treatment and placebo in older Chinese patients with isolated systolic hypertension
[ PUBLICATION ]
BACKGROUND: Isolated systolic hypertension occurs in around 8% of Chinese people aged 60 years or older. In 1988, the Systolic Hypertension in China (Syst-China) Collaborative Group started to investigate whether active treatment could reduce the incidence of stroke and other cardiovascular complications in older patients with isolated systolic hypertension.
METHODS: All patients were initially started on masked placebo. After stratification for centre, sex and previous cardiovascular ...
| Known for Active Treatment | Systolic Hypertension | Older Chinese Patients | 1000 Patientyears | Cardiovascular Endpoints |
OBJECTIVE: To reach a consensus on the prognostic significance of new techniques of automated blood pressure measurement.
METHODS: A Task Force on the prognostic significance of ambulatory blood pressure monitoring wrote this review in preparation for the Eighth International Consensus Conference (28-31 October 2001, Sendai, Japan). This synopsis was amended to account for opinions aired at the conference and to reflect the common ground reached in the discussions.
POINTS OF CONSENSUS: ...
| Known for Blood Pressure | Task Force | Ambulatory Monitoring | Whitecoat Hypertension | Qkd Interval |
Angiotensin-Converting Enzyme Inhibitors and Calcium Channel Blockers for Coronary Heart Disease and Stroke Prevention
[ PUBLICATION ]
We investigated whether protection from coronary heart disease (CHD) and stroke conferred by angiotensin-converting enzyme inhibitors (ACEIs) and calcium channel blockers (CCBs) in hypertensive or high-risk patients may be explained by the specific drug regimen. We extracted summary statistics regarding CHD and stroke from 28 outcome trials that compared either ACEIs or CCBs with diuretics, beta-blockers, or placebo for a total of 179,122 patients, 9509 incident cases of CHD, and 5971 ...
| Known for Stroke Prevention | Channel Blockers | Coronary Heart Disease | Enzyme Inhibitors | Risk Chd |
Effect of Age on Brachial Artery Wall Properties Differs From the Aorta and Is Gender Dependent
[ PUBLICATION ]
Compliance and distensibility are wall properties of large arteries, which may play a role in cardiovascular disease. The purpose of this study was to investigate whether the influence of age on these vessel wall properties differs between vascular territories and is gender-dependent. In a population sample of 498 men and women 20 to 79 years of age, diameter, distensibility, and compliance coefficient of the muscular brachial artery were measured with an echo-tracking device. ...
| Known for Brachial Artery | Wall Properties | Age Distensibility | Aging Analysis | Aorta Blood |
Fatal and Nonfatal Outcomes, Incidence of Hypertension, and Blood Pressure Changes in Relation to Urinary Sodium Excretion
[ PUBLICATION ]
CONTEXT: Extrapolations from observational studies and short-term intervention trials suggest that population-wide moderation of salt intake might reduce cardiovascular events.
OBJECTIVE: To assess whether 24-hour urinary sodium excretion predicts blood pressure (BP) and health outcomes.
DESIGN, SETTING, AND PARTICIPANTS: Prospective population study, involving 3681 participants without cardiovascular disease (CVD) who are members of families that were randomly enrolled in the Flemish ...
| Known for Sodium Excretion | Blood Pressure | Risk Hypertension | Health Outcomes | Increasing Tertiles |
Predicting Cardiovascular Risk Using Conventional vs Ambulatory Blood Pressure in Older Patients With Systolic Hypertension
[ PUBLICATION ]
CONTEXT: The clinical use of ambulatory blood pressure (BP) monitoring requires further validation in prospective outcome studies.
OBJECTIVE: To compare the prognostic significance of conventional and ambulatory BP measurement in older patients with isolated systolic hypertension.
DESIGN: Substudy to the double-blind placebo-controlled Systolic Hypertension in Europe (Syst-Eur) Trial, started in October 1988 with follow up to February 1999. The conventional BP at randomization was the ...
| Known for Cardiovascular Risk | Systolic Hypertension | Ambulatory Blood | Mm Hg | Topic Reproducibility |
Diagnostic Thresholds for Ambulatory Blood Pressure Monitoring Based on 10-Year Cardiovascular Risk
[ PUBLICATION ]
BACKGROUND: Current diagnostic thresholds for ambulatory blood pressure (ABP) mainly rely on statistical parameters derived from reference populations. We determined an outcome-driven reference frame for ABP measurement.
METHODS AND RESULTS: We performed 24-hour ABP monitoring in 5682 participants (mean age 59.0 years; 43.3% women) enrolled in prospective population studies in Copenhagen, Denmark; Noorderkempen, Belgium; Ohasama, Japan; and Uppsala, Sweden. In multivariate analyses, we ...
| Known for Diagnostic Thresholds | Pressure Monitoring | Mm Hg | Cardiovascular Risk | Ambulatory Blood |
Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension
[ PUBLICATION ]
BACKGROUND: Isolated systolic hypertension occurs in about 15% of people aged 60 years or older. In 1989, the European Working Party on High Blood Pressure in the Elderly investigated whether active treatment could reduce cardiovascular complications of isolated systolic hypertension. Fatal and non-fatal stroke combined was the primary endpoint.
METHODS: All patients (> 60 years) were initially started on masked placebo. At three run-in visits 1 month apart, their average sitting ...
| Known for Active Treatment | Isolated Systolic Hypertension | Cardiovascular Complications | Patients 60 Years | Mm Hg |
Environmental exposure to cadmium, forearm bone density, and risk of fractures: prospective population study
[ PUBLICATION ]
BACKGROUND: Chronic low-level exposure to cadmium may promote calcium loss via urinary excretion. We undertook a prospective population study to investigate whether environmental exposure to cadmium lowers bone density and increases risk of fractures.
METHODS: We measured urinary cadmium excretion, a biomarker of lifetime exposure, in people from ten districts of Belgium, of which six districts bordered on three zinc smelters. We also measured cadmium in soil and in vegetables from the ...
| Known for Environmental Exposure | Bone Density | Cadmium Soil | Risk Fractures | Urinary Excretion |
The Prevention of Dementia With Antihypertensive Treatment: New Evidence From the Systolic Hypertension in Europe (Syst-Eur) Study
[ PUBLICATION ]
BACKGROUND: After the double-blind, placebo-controlled Systolic Hypertension in Europe (Syst-Eur) trial ended in February 1997, randomized patients were offered active study medication for a further period of observation.
OBJECTIVE: To refine the estimates of the long-term effects of antihypertensive therapy on the incidence of dementia.
METHODS: Eligible patients had no dementia and were at least 60 years old. Their systolic blood pressure at entry was 160 to 219 mm Hg, with diastolic ...
| Known for Systolic Hypertension | Antihypertensive Treatment | Incidence Dementia | New Evidence | Doubleblind Trial |
BACKGROUND: In a meta-analysis published in October 2001, we reported that new and old classes of antihypertensive drugs had similar long-term efficacy and safety. Furthermore, we observed that in clinical trials in hypertensive or high-risk patients gradients in systolic pressure accounted for most differences in outcome.
OBJECTIVE: To test whether our previous conclusions would hold, we updated our quantitative overview with new information from 14 clinical trials presented before 1 ...
| Known for Blood Pressure | Cardiovascular Prevention | Antihypertensive Drugs | Myocardial Infarction | Ace Inhibitors |
