Anne Marie Tjønneland

Anne Marie Tjønneland

Department of Public Health, University of Copenhagen, DK-2100 Copenhagen, Denmark | Danish Cancer Society Research Center, Diet, Genes and Environment, Nutrition and ...

KOL Resume for Anne Marie Tjønneland  (disorders breast, disorders, breast, disease)


Department of Public Health, University of Copenhagen, DK-2100 Copenhagen, Denmark

Diet, Genes and Environment (DGE), Bonn, Germany


Danish Cancer Society Research Centre, Copenhagen, Denmark


Department of Public Health, University of Copenhagen K, DK-1165, Copenhagen, Denmark

Danish Cancer Society Research Center, Diet, Genes and Environment (DGE), Copenhagen, Germany

Hellenic Health Foundation, Athens, Greece


Prominent publications by Anne Marie Tjønneland

KOL Index score: 23482

BACKGROUND: Underweight, overweight, and obesity in childhood and adolescence are associated with adverse health consequences throughout the life-course. Our aim was to estimate worldwide trends in mean body-mass index (BMI) and a comprehensive set of BMI categories that cover underweight to obesity in children and adolescents, and to compare trends with those of adults.

METHODS: We pooled 2416 population-based studies with measurements of height and weight on 128·9 million participants ...

Known for Worldwide Trends |  Bmi Prevalence |  Pooled Analysis |  1 2 |  Boys Obesity
KOL Index score: 21260

BACKGROUND: The xenobiotic transporters, Multidrug Resistance 1 (MDR1/ABCB1) and Breast Cancer Resistance Protein (BCRP/ABCG2) may restrict intestinal absorption of various carcinogens, including heterocyclic amines (HCA) and polycyclic aromatic hydrocarbons (PAH). Cyclooxygenase-2 (COX-2) derived prostaglandins promote gastrointestinal carcinogenesis, affecting angiogenesis, apoptosis, and invasiveness.The aim of this study was to investigate if polymorphisms in these genes were ...

Known for Multidrug Resistance |  Meat Intake |  Colorectal Cancer |  Crc Risk |  Mdr1 Polymorphisms
KOL Index score: 20200

BACKGROUND: Body weight and body mass index (BMI) are positively related to risk of colon cancer in men, whereas weak or no associations exist in women. This discrepancy may be related to differences in fat distribution between sexes or to the use of hormone replacement therapy (HRT) in women.

METHODS: We used multivariable adjusted Cox proportional hazards models to examine the association between anthropometric measures and risks of colon and rectal cancer among 368 277 men and women ...

Known for Body Size |  Rectal Cancer |  Women 95 |  Anthropometric Measures |  Whr Risk
KOL Index score: 18865

BACKGROUND: Studies indicate an effect of dietary calcium on change in body weight (BW) and waist circumference (WC), but the results are inconsistent. Furthermore, a relation could depend on genetic predisposition to obesity.

OBJECTIVE: The objective was to examine whether genetic predisposition to higher body mass index (BMI), WC, or waist-hip ratio (WHR) interacts with dietary calcium in relation to subsequent annual change in BW (ΔBW) and WC (ΔWC).

DESIGN: The study was based on 7569 ...

Known for Genetic Predisposition |  Dietary Calcium |  Waist Circumference |  Δbw Δwc |  Bmi Wc
KOL Index score: 18614

BACKGROUND: Comparable global data on health and nutrition of school-aged children and adolescents are scarce. We aimed to estimate age trajectories and time trends in mean height and mean body-mass index (BMI), which measures weight gain beyond what is expected from height gain, for school-aged children and adolescents.

METHODS: For this pooled analysis, we used a database of cardiometabolic risk factors collated by the Non-Communicable Disease Risk Factor Collaboration. We applied a ...

Known for Boys Girls |  Children Adolescents |  Bmi Height |  Weight Gain |  Mass Child
KOL Index score: 17885

Importance: Low-density lipoprotein cholesterol (LDL-C)-lowering alleles in or near NPC1L1 or HMGCR, encoding the respective molecular targets of ezetimibe and statins, have previously been used as proxies to study the efficacy of these lipid-lowering drugs. Alleles near HMGCR are associated with a higher risk of type 2 diabetes, similar to the increased incidence of new-onset diabetes associated with statin treatment in randomized clinical trials. It is unknown whether alleles near ...

Known for Type 2 Diabetes |  Lowering Genetic |  Density Lipoprotein |  Coronary Artery Disease |  Ldl Risk
KOL Index score: 17587

BACKGROUND: Dietary factors are thought to have an important role in gastric and esophageal carcinogenesis, but evidence from cohort studies for such a role is lacking. We examined the risks of gastric cancer and esophageal adenocarcinoma associated with meat consumption within the European Prospective Investigation Into Cancer and Nutrition (EPIC) cohort.

METHODS: A total of 521,457 men and women aged 35-70 years in 10 European countries participated in the EPIC cohort. Dietary and ...

Known for Esophageal Adenocarcinoma |  Meat Intake |  European Prospective |  Risk Gastric |  Cardia Cancer
KOL Index score: 17401

Polymorphisms in the XPD and the XPC gene have been associated with a lower DNA repair capacity. We determined the risk of colorectal cancer in association with the four polymorphisms XPA A23G, XPC Lys939Gln, XPD Lys751Gln and XPD Asp312Asn, and interactions between the polymorphisms and the environmental factors: smoking intensity, intake of alcohol, red meat, processed meat, fish and poultry, fruits and vegetables and dietary fibres, in relation to development of colorectal cancer in a ...

Known for Xpc Lys939gln |  Xpd Lys751gln |  Colorectal Cancer |  Asp312asn Polymorphisms |  Xpa A23
KOL Index score: 17312

BACKGROUND: Hypertension can be detected at the primary health-care level and low-cost treatments can effectively control hypertension. We aimed to measure the prevalence of hypertension and progress in its detection, treatment, and control from 1990 to 2019 for 200 countries and territories.

METHODS: We used data from 1990 to 2019 on people aged 30-79 years from population-representative studies with measurement of blood pressure and data on blood pressure treatment. We defined ...

Known for Hypertension Prevalence |  Treatment Control |  Pooled Analysis |  Income Countries |  Costa Rica
KOL Index score: 17261

INTRODUCTION: Associations of hormone-receptor positive breast cancer with excess adiposity are reasonably well characterized; however, uncertainty remains regarding the association of body mass index (BMI) with hormone-receptor negative malignancies, and possible interactions by hormone replacement therapy (HRT) use.

METHODS: Within the European EPIC cohort, Cox proportional hazards models were used to describe the relationship of BMI, waist and hip circumferences with risk of ...

Known for Hormone Receptor |  Cancer Risk |  Bmi Hrt |  Replacement Therapy |  Erpr Tumors
KOL Index score: 17099

BACKGROUND: Raised blood pressure is an important risk factor for cardiovascular diseases and chronic kidney disease. We estimated worldwide trends in mean systolic and mean diastolic blood pressure, and the prevalence of, and number of people with, raised blood pressure, defined as systolic blood pressure of 140 mm Hg or higher or diastolic blood pressure of 90 mm Hg or higher.

METHODS: For this analysis, we pooled national, subnational, or community population-based studies that had ...

Known for Blood Pressure |  Worldwide Trends |  Pooled Analysis |  South Asia |  Subsaharan Africa
KOL Index score: 16557

BACKGROUND: Contrasting etiologic hypotheses about the role of endogenous sex steroids in breast cancer development among premenopausal women implicate ovarian androgen excess and progesterone deficiency, estrogen excess, estrogen and progesterone excess, and both an excess or lack of adrenal androgens (dehydroepiandrosterone [DHEA] or its sulfate [DHEAS]) as risk factors. We conducted a case-control study nested within the European Prospective Investigation into Cancer and Nutrition ...

Known for Breast Cancer |  Premenopausal Women |  Sex Steroids |  Menstrual Cycle |  European Prospective
KOL Index score: 16443

Lung cancer risk was investigated in relation to single nucleotide polymorphisms in genes involved in the inflammatory response. The aim was to see if polymorphisms modifying the inflammatory response are associated with risk of lung cancer and if there were interactions between the same polymorphism and factors, which modify an inflammatory response, such as smoking status, duration, and intensity, and use of NSAID. The functional SNPs IL-1B T-31C, IL6 G-174C, IL8 T-251A, IL10 C-592T, ...

Known for Lung Cancer |  Inflammatory Response |  Interaction Nsaid |  Polymorphisms Genes |  Cox2 A1195
KOL Index score: 16215

BACKGROUND: Circulating levels of insulin-like growth factor I (IGF-I) and its main binding protein, IGF binding protein 3 (IGFBP-3), have been associated with risk of several types of cancer. Heritable factors explain up to 60% of the variation in IGF-I and IGFBP-3 in studies of adult twins.

METHODS: We systematically examined common genetic variation in 18 genes in the IGF signaling pathway for associations with circulating levels of IGF-I and IGFBP-3. A total of 302 single nucleotide ...

Known for Binding Protein |  Circulating Levels |  Growth Factor |  Breast Cancer |  Pathway Genes
KOL Index score: 15894

BACKGROUND: More than 50% of the colorectal cancer (CRC) etiology has been attributed to diet. Established or suspected dietary factors modifying risk of CRC are red meat, cereals, fish, and fibre. Diet and lifestyle may be linked to cancer through inflammation. Interleukin-10 (IL-10) is an anti-inflammatory cytokine. We wanted to test if dietary factors and IL10 polymorphisms interact in relation to colorectal carcinogenesis.

METHODS: The functional IL10 polymorphism C-592A (rs1800872) ...

Known for Colorectal Cancer |  Dietary Fibre |  Crc Interaction |  Relation Risk |  Diet Lifestyle


Anne Marie Tjønneland: Influence Statistics

Sample of concepts for which Anne Marie Tjønneland is among the top experts in the world.
Concept World rank
hrtmethodsa #1
women ptg #1
smoking stratification stratification #1
glycemic postmenopausal women #1
health biobank #1
baseline 1993 #1
decaffeinated coffee 95 #1
scandinavian helga cohort #1
lower incidence crc #1
meat fatty fish #1
il10 ptgs2 #1
associations observed #1
association hrt #1
neoplasms proportional #1
g1464c #1
case cohort study #1
42972 #1
tea consumption risk #1
dwc risk #1
higher levels igfii #1
macronutrient substitutions #1
wholegrain products #1
intake healthy diet #1
investigated association #1
proportional hazard models #1
wg norway #1
plasma pfoa pfos #1
rr090 #1
aarhus area #1
women rye bread #1
crp genetic variation #1
studies waist #1
cancermediation #1
day yogurt #1
vte risk grs #1
bcdesignwe #1
adherence lower risk #1
26691 #1
diabetes lower risk #1
health cohort #1
hqol diagnosis #1
26122 #1
75–150 #1
risk european #1
intake wg #1
476160 #1
gastric cancer pm25 #1
nested casecohort study #1
association grains #1
foods questionnaire #1

Key People For Breast Cancer

Top KOLs in the world
Ahmedin M Jemal
united states breast cancer addis ababa
Gabriel N Hortobagyi
breast cancer neoadjuvant chemotherapy estrogen receptors
Rebecca L Siegel
united states colorectal cancer incidence rates
Charles M Perou
breast cancer gene expression intrinsic subtypes
Freddie Ian Bray
cancer incidence nordic countries mortality rates
Jacques Ferlay
cancer incidence global burden latin america

Anne Marie Tjønneland:Expert Impact

Concepts for whichAnne Marie Tjønnelandhas direct influence:Breast cancer,  Colorectal cancer,  Cancer risk,  Prostate cancer,  Lung cancer,  Pancreatic cancer,  Type 2 diabetes,  Waist circumference.

Anne Marie Tjønneland:KOL impact

Concepts related to the work of other authors for whichfor which Anne Marie Tjønneland has influence:Breast cancer,  Physical activity,  Alcohol consumption,  Air pollution,  Type 2 diabetes,  Metabolic syndrome,  Cardiovascular disease.



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Department of Public Health, University of Copenhagen, DK-2100 Copenhagen, Denmark | Danish Cancer Society Research Center, Diet, Genes and Environment, Nutrition and Biomarkers (NAB), Copenhagen, Denmark | The Danish Cancer Society Research Centre,

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