• breast cancer
    • Di Di Wu

      Di Di Wu

      Department of Cardiology, Hainan Hospital of Chinese People’s Liberation Army General Hospital, Sanya, China | Department of electrical and computer engineering, North Dakota ...



      KOL Resume for Di Di Wu


      Department of Cardiology, Hainan Hospital of Chinese People’s Liberation Army General Hospital, Sanya, China

      Electrical and Computer Engineering, North Dakota State University, Fargo, ND, USA

      Hannover Centre for Optical Technologies, Leibniz University of Hannover, Hannover, Germany

      affiliation not provided to SSRN

      Samsung AI Center, Montreal, QC, H3B 4W8, Canada



      Di Di Wu: Influence Statistics

      Sample of concepts for which Di Di Wu is among the top experts in the world.
      Concept World rank
      zwitterionic thermosensitive #1
      2ethylaminomethyl6methoxyphenol #1
      exposure hsp70 #1
      bond h⋯e⋯h #1
      gammatone spectral #1
      case shc #1
      node consumption energy #1
      gz gz microgravity #1
      mitochondrion mechanism #1
      ctb technology #1
      6dvnet #1
      translation teachers translation #1
      shafthull #1
      daqing fields #1
      shijiahe #1
      chickens hsps #1
      microgravity gz #1
      latitude features #1
      dark tourism tourists #1
      hydrogel response relationship #1
      exosomes nlf #1
      delivery lovastatin #1
      motile aeromonas septicaemia #1
      gammatone spectral latitude #1
      tubal tuberculosis #1
      hcn···hnc hnc···hnc #1
      proline puckering parameters #1
      developing translator #1
      translator trainers #1
      lidar geometric #1
      hnc···hnc dimers #1
      pyraclostrobin kg1 #1
      parameters collagen #1
      emotional experience awe #1
      tone ipo prospectuses #1
      injectable zwitterionic #1
      prophylactic ankle braces #1
      offgoing brake #1
      dark tourism study #1
      crowdfunding features #1
      translation teachers #1
      pathway sepsis #1
      ctb technology ctb #1
      hyperpolarizabilities dimers #1
      trainers beliefs #1
      active multistrut assembly #1
      tbend liquid permeation #1
      translator competence competences #1
      handling produced fluid #1
      mek5 inhibitors #1


      Prominent publications by Di Di Wu

      KOL-Index: 16641

      Depressive symptoms have been in the limelight for many kinds of people, but few studies have explored positive resources for combating depressive symptoms among Chinese nurses. The purpose of this study is to explore the association between work-family conflict (WFC) and depressive symptoms among Chinese female nurses, along with the mediating and moderating role of psychological capital (PsyCap) in this relationship. This cross-sectional study was completed during the period of ...

      Known for Depressive Symptoms | Psychological Capital | Moderating Role | Psycap Relationship | Female Nurses
      KOL-Index: 15606

      The purpose of this study was to investigate the effect of manganese (Mn)-induced cytotoxicity on heat shock proteins in chicken spleen lymphocytes. Lymphocytes were cultured in medium in the absence and presence of MnCl2 (2 × 10−4, 4 × 10−4, 6 × 10−4, 8 × 10−4, 10 × 10−4, and 12 × 10−4 mmol/L) for 12, 24, 36, and 48 h in vitro. Then, the mRNA levels of HSP27, HSP40, HSP60, HSP70, and HSP90 were examined by real-time quantitative PCR. The results showed that the mRNA levels of HSP27, ...

      Known for Mrna Expression | Spleen Lymphocytes | Hsp60 Hsp70 | Heat Shock Proteins | Vitro Hsp27
      KOL-Index: 12947

      Our previous proteomics study revealed that thioredoxin-interacting protein (TXNIP) was down-regulated by miR-373. However, little is known of the mechanism by which miR-373 decreases TXNIP to stimulate metastasis. In this study, we show that miR-373 promotes the epithelial-to-mesenchymal transition (EMT) in breast cancer. MiR-373 suppresses TXNIP by binding to the 3'UTR of TXNIP, which in turn, induces cancer cell EMT and metastasis. TXNIP co-expression, but not the TXNIP-3'UTR, ...

      Known for Breast Cancer | Mesenchymal Transition | Migration Invasion | Neoplastic Humans | Hypoxiainducible Factor
      KOL-Index: 12597

      BACKGROUND/OBJECTIVE: Inadvertent intraoperative hypothermia (core temperature <360 C) is a recognized risk in surgery and has adverse consequences. However, no data about this complication in China are available. Our study aimed to determine the incidence of inadvertent intraoperative hypothermia and its associated risk factors in a sample of Chinese patients.

      METHODS: We conducted a regional cross-sectional survey in Beijing from August through December, 2013. Eight hundred thirty ...

      Known for General Anesthesia | Intraoperative Hypothermia | Active Warming | Incidence Risk Factors | Patients Major Operations
      KOL-Index: 12023

      BACKGROUND/AIMS: Dexmedetomidine (Dex), a specific agonist of α2-adrenoceptor, has been reported to have extensive pharmacological effects. In this study, we focused on the protective effect of Dex on hyperoxia-induced acute lung injury and further explored its possible molecular mechanisms.

      METHODS: The model of hyperoxia-induced acute lung injury was established by continuous inhalation of oxygen (FiO2= 0.90) for 7 d in neonatal rats in vivo. The in vitro experiments were carried out ...

      Known for Lung Injury | Induced Acute | Nlrp3 Inflammasome | Dexmedetomidine Alleviates | Dex Treatment
      KOL-Index: 11519

      OBJECTIVES: To explore the correlations among social isolation and symptoms of anxiety and depression among patients with breast cancer in China and to further verify the mediating role of social support in social isolation and symptoms of depression or anxiety.

      DESIGN: A cross-sectional survey.

      SETTINGS: The cluster sampling method was conducted for 456 female inpatients diagnosed with breast cancer at the Tumor Hospital Affiliated of Harbin Medical University from April 2019-September ...

      Known for Social Support | Breast Cancer | Anxiety Depression | Negatively Correlated
      KOL-Index: 11266

      Diabetes is a complex metabolic syndrome that is characterized by prolonged high blood glucose levels and frequently associated with life-threatening complications1,2. Epidemiological studies have suggested that diabetes is also linked to an increased risk of cancer3–5. High glucose levels may be a prevailing factor that contributes to the link between diabetes and cancer, but little is known about the molecular basis of this link and how the high glucose state may drive genetic and/or ...

      Known for Tet2 Ampk | Diabetes Cancer | Glucose Levels | Dna 5 | Metformin Mice
      KOL-Index: 10867

      Mutations in SPOP, the gene encoding a component of the E3 ubiquitin ligase complex, impair ubiquitination-dependent degradation of BRD2, BRD3 and BRD4 proteins and result in activation of ATK–mTORC1 signaling and resistance to BET inhibitors. Pharmacological blockade of AKT represents a viable strategy to restore the sensitivity of SPOP-mutant prostate tumors to BET inhibitors. These results, together with findings by Dai et al. and Janouskova et al., uncover a new nongenetic mechanism ...

      Known for Bet Protein | Spop Gene | Prostate Cancer | Inhibitor Resistance | Serine Threonine
      KOL-Index: 10741

      243 surface soil samples were collected from the Yangtze River Delta (YRD) region, and the concentration distributions and compositional profiles of 27 parent PAHs (PPAHs), nitro- and oxy-derivatives (NPAHs and OPAHs), respectively, and health risk of 16 PPAHs were determined. Atmospheric samples were collected at two sites with high topsoil concentrations of PAHs to assist in identifying the emission sources of PPAHs. The total concentrations of PPAHs, NPAHs and OPAHs fell in the ranges ...

      Known for Yangtze River Delta | Spatial Distribution | Surface Soil | Npahs Opahs | Parent Pahs
      KOL-Index: 9785

      Human dental pulp stem cells (DPSCs) are oral mesenchymal stem cells with potential to differentiate into various cell types. Recent studies of DPSCs have focused on microRNAs (miRNAs), a class of small noncoding RNAs that play crucial roles in regulating DPSC phenotypes. In the current study, the expression of miR-140-5p was significantly decreased during lipopolysaccharide (LPS)-mediated differentiation of DPSCs in vitro. Overexpression of miR-140-5p enhanced proliferation of DPSCs and ...

      Known for Stem Cells | Dental Pulp | Receptor 4 | Dpsc Proliferation Differentiation | Cell Proliferation
      KOL-Index: 9758

      BACKGROUND: Patients with advanced hematologic malignancies remain at risk for relapse following reduced-intensity conditioning (RIC) allogeneic hematopoietic stem cell transplantation (allo-HSCT). We conducted a prospective clinical trial to test whether vaccination with whole leukemia cells early after transplantation facilitates the expansion of leukemia-reactive T cells and thereby enhances antitumor immunity.

      METHODS: We enrolled 22 patients with advanced chronic lymphocytic ...

      Known for Cell Vaccination | Chronic Lymphocytic | Autologous Cll | Vaccinated Patients | Antitumor Immunity
      KOL-Index: 9247

      Sucrose (Suc) transporters (SUCs or SUTs) are important regulators in plant growth and stress tolerance. However, the mechanism of SUCs in plant abiotic stress resistance remains to be dietermined. Here, we found that AtSUC9 expression was induced by abiotic stress, including salt, osmotic and cold stress conditions. Disruption of AtSUC9 led to sensitive responses to abiotic stress during seed germination and seedling growth. Further analyses indicated that the sensitivity phenotype of ...

      Known for Abiotic Stress | Sucrose Transporter | Plant Growth | Seed Germination | Transport Proteins
      KOL-Index: 8971

      Small-cell lung cancer (SCLC) is a highly aggressive subtype of lung cancer with limited treatment options. CD47 is a cell-surface molecule that promotes immune evasion by engaging signal-regulatory protein alpha (SIRPα), which serves as an inhibitory receptor on macrophages. Here, we found that CD47 is highly expressed on the surface of human SCLC cells; therefore, we investigated CD47-blocking immunotherapies as a potential approach for SCLC treatment. Disruption of the interaction of ...

      Known for Lung Cancer | Antigen Cell | Sclc Treatment | Cd47blocking Therapies | Disruption Cd47 Sirpα
      KOL-Index: 8957

      Objective To analyze the characteristics of high risk sexual behaviors and HIV infectious status among men who have sex with men (MSM) who use drugs in Tianjin in 2016. Methods From April to December in 2016, MSM who use drugs in Tianjin were targetedly and extensively mobilized to receive testing by snowball sampling method. The inclusion criteria were as follows: men aged 18 years old and above; have had oral or anal sex with men in the last 6 months; have had drug abuse history in ...

      Known for Hiv Infection | Sex Msm | Risk Behaviors | 6 Months | Drug Abuse

      Key People For Breast Cancer

      Top KOLs in the world
      Ahmedin M Jemal
      united states breast cancer addis ababa
      Gabriel N Hortobagyi
      breast cancer neoadjuvant chemotherapy estrogen receptors
      Rebecca L Siegel
      united states colorectal cancer incidence rates
      Charles M Perou
      breast cancer gene expression intrinsic subtypes
      Freddie Ian Bray
      cancer incidence nordic countries mortality rates
      Jacques Ferlay
      cancer incidence global burden latin america

      Di Di Wu:Expert Impact

      Concepts for whichDi Di Wuhas direct influence:Breast cancer,  Osteogenic differentiation,  Asp flooding,  Proton transfer.

      Di Di Wu:KOL impact

      Concepts related to the work of other authors for whichfor which Di Di Wu has influence:Polycystic ovary syndrome,  Breast cancer,  Gut microbiota,  Gene expression,  Oxidative stress,  Cell proliferation,  Visible light.



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      Department of Cardiology, Hainan Hospital of Chinese People’s Liberation Army General Hospital, Sanya, China | Department of electrical and computer engineering, North Dakota State University, Fargo, USA | Guangdong Key Laboratory of Big Data Analysi

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