• breast cancer
    • Hui Hui Li

      Hui Hui Li

      Faculty of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8572, Japan. | Shanghai Institute of Materia Medica Chinese Academy of ...



      KOL Resume for Hui Hui Li




      Hui Hui Li: Influence Statistics

      Sample of concepts for which Hui Hui Li is among the top experts in the world.
      Concept World rank
      ivnkl #1
      terminal n‐vinylazoles #1
      tension strain #1
      china pics #1
      new targets ifi6 #1
      microinflammatory state #1
      consistency cpgs #1
      heavy oil sands #1
      myotube degeneration #1
      qualitative guidelines #1
      homologous tier #1
      erchen decoction #1
      ratio percentage #1
      hochschild cohomology #1
      neutralisation functions #1
      mulam #1
      plane turbulent jet #1
      2019ncov pneumonia #1
      track irregularity #1
      multichannel management #1
      microalloying process #1
      digital products #1
      distribution china #1
      flow pneumatic conveying #1
      meat consumption depression #1
      housing rentals #1
      uaf protocol #1
      vot2021 challenge #1
      abnormal nuclear aggregation #1
      stainless steel bars #1
      lcs slns #1
      carrot consumption #1
      breast cancer mir202 #1
      flour substrate #1
      riog #1
      epb41l1 gbm cells #1
      networks link prediction #1
      dlspfhs #1
      chimeric rna #1
      circle actions #1
      elderly patients china #1
      precipitation kinetic #1
      hsacirc001653 #1
      glioma cells tmz #1
      variational treatment #1
      stacking transformation #1
      snail1 twist1 #1
      tmj ankylosis patients #1
      multiarc roots #1
      development trend #1


      Prominent publications by Hui Hui Li

      KOL-Index: 20782

      BackgroundThe present study was carried out to determine whether a quantitative relationship exists between the expressions of 3 cancer stem cell (CSC) markers and the degree of differentiation of gastric cancer.MethodsThe expressions of 3 putative CSC markers, ABCB1, ABCG2, and CD133, were detected in 90 human gastric adenocarcinoma cases by immunofluorescence assay. The differentiation statuses of 3 gastric cancer cell lines (the undifferentiated gastric cancer cell line HGC-27, the ...

      Known for Gastric Cancer | Cell Markers | Binding Cassette | Transporter Subfamily | Mice Nude
      KOL-Index: 15726

      OBJECTIVES: Hypertension is an important public health problem in rural China with a rapidly increasing prevalence noted in recent years. This study estimates the prevalence, awareness, treatment and control of hypertension in a rural population in Shandong Province, China.

      METHODS: A cross-sectional study was conducted in rural Shandong Province, China, in April 2007 using multistage cluster sampling. A total of 16 364 rural residents aged 25 years and more were interviewed and ...

      Known for Shandong Province | Rural China | Control Hypertension | Awareness Treatment | Hypertensive Patients
      KOL-Index: 15467

      PURPOSE: To evaluate the use of dual-energy spectral computed tomographic (CT) quantitative parameters compared with the use of conventional CT imaging features for preoperative diagnosis of metastasis to the cervical lymph nodes in patients with papillary thyroid cancer.

      MATERIALS AND METHODS: This study was approved by the ethics committee and all patients provided written informed consent. Analyses of quantitative gemstone spectral imaging data and qualitative conventional CT imaging ...

      Known for Preoperative Diagnosis | Papillary Thyroid Cancer | Quantitative Parameters | Cervical Lymph | Venous Phase
      KOL-Index: 15379

      BACKGROUND: Resistance to temozolomide (TMZ) in glioma is modulated by the DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT). This study aimed to examine the effects of fluoxetine (FLT) on MGMT expression in glioma cells and to investigate its underlying mechanisms.

      MATERIALS AND METHODS: Expression of MGMT, GluR1, or IκB kinase β (IKKβ) was attenuated using short hairpin RNA-mediated gene knockdown. The 3-(4,5-dimethylthiazol -2-yl)-2,5-diphenyltetrazolium bromide (MTT) ...

      Known for Glioma Cells | Mgmt Expression | Flt Tmz | Nf Κb | Xenograft Model
      KOL-Index: 15291

      BACKGROUND: Intensive lifestyle interventions can reduce the incidence of type 2 diabetes in people with impaired glucose tolerance, but how long these benefits extend beyond the period of active intervention, and whether such interventions reduce the risk of cardiovascular disease (CVD) and mortality, is unclear. We aimed to assess whether intensive lifestyle interventions have a long-term effect on the risk of diabetes, diabetes-related macrovascular and microvascular complications, ...

      Known for Lifestyle Intervention | Diabetes Control | Year Follow | Diet Exercise | Longterm Risk
      KOL-Index: 15013

      BACKGROUND: Lifestyle interventions can delay the onset of type 2 diabetes in people with impaired glucose tolerance, but whether this leads subsequently to fewer complications or to increased longevity is uncertain. We aimed to assess the long-term effects of lifestyle interventions in people with impaired glucose tolerance on the incidence of diabetes, its complications, and mortality.

      METHODS: The original study was a cluster randomised trial, started in 1986, in which 33 clinics in ...

      Known for Lifestyle Intervention | Glucose Tolerance | Incidence Diabetes | Microvascular Complications | 30 Years
      KOL-Index: 14982

      OBJECTIVES: Concentrations of 17 polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) and 18 polychlorinated biphenyls (PCBs) were measured in 11 varieties of food groups collected from retail market of Shenzhen, Guangdong province, China from 2004 to 2006. PCDD/Fs and PCBs dietary intake from varies food for the local population was estimated in the study.

      METHODS: Concentrations of 17 polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) and 12 dioxin-like ...

      Known for Dietary Intake | Pcdd Pcbs | Retail Foods | Food Groups | Shenzhen China
      KOL-Index: 14841

      Numerous studies have shown that aberrant microRNA (miRNA) expression is associated with the development and progression of various types of human cancer and serum miRNAs are potential biomarkers. This study examined whether some commonly deregulated miRNAs in hepatocellular carcinoma (HCC) are presented in serum of patients with HCC and can serve as diagnostic markers. Serum miRNAs (miR-21, miR-122, and miR-223) were quantified by real-time quantitative RT-PCR in 101 patients with HCC ...

      Known for Chronic Hepatitis | Hcc Patients | Hepatocellular Carcinoma | Mir122 Mir223 | Serum Mirnas
      KOL-Index: 14764

      BACKGROUND: No therapeutics have yet been proven effective for the treatment of severe illness caused by SARS-CoV-2.

      METHODS: We conducted a randomized, controlled, open-label trial involving hospitalized adult patients with confirmed SARS-CoV-2 infection, which causes the respiratory illness Covid-19, and an oxygen saturation (Sao2) of 94% or less while they were breathing ambient air or a ratio of the partial pressure of oxygen (Pao2) to the fraction of inspired oxygen (Fio2) of less ...

      Known for Standard Time | Ritonavir Sars | Severe Illness | Treatment Lopinavir | Clinical Improvement
      KOL-Index: 14600

      BACKGROUND: Anti-malarial drug artesunate (ART), a semi-synthetic derivative of artemisnin, has immunosuppressive effects on several autoimmune diseases, including Systemic lupus erythematosus (SLE), Rheumatoid arthritis (RA), and Colitis. However, molecular mechanisms of ART, especially on follicular helper T cells (Tfh), central players in SLE pathology, are far from clear.

      PURPOSE: The object for this work is to investigate the therapeutic effect of ART on lupus-prone MRL/lpr mice and ...

      Known for Lpr Mice | Therapeutic Effects | Tfh Cells | Cell Differentiation | Follicular Helper
      KOL-Index: 14517

      BackgroundColorectal cancer (CRC) poses a heavy threat to human health owing to its high incidence and mortality. Circular RNAs (circRNAs) were investigated to participate in the progression of CRC, whereas there was no revenant data on the CRC process regulated by hsa_circ_0000231. This study aimed to explore the effects of hsa_circ_0000231 on CRC progression and underneath regulatory mechanism.MethodsThe expression levels of hsa_circ_0000231, miR-502-5p, and Myosin VI (MYO6) mRNA were ...

      Known for Hsacirc0000231 Crc | 5p Myo6 | Colorectal Cancer | Proliferation Migration | Circular Rna
      KOL-Index: 14476

      ObjectiveFew data are available on the epidemiology of HPV and cervical cancer among Chinese women younger than 25 years old. This study aimed to estimate the HPV infection rate and the prevalence of cervical intraepithelial neoplasia (CIN) in women aged 18–25, as well as their knowledge of and attitudes towards HPV vaccination.MethodsA population-based cervical cancer screening study was conducted on women aged 18–25 in Jiangsu province in 2008. Participants provided socio-demographic, ...

      Known for Hpv Vaccination | Chinese Women | Cervical Intraepithelial | Aged 18–25 | Educational Intervention
      KOL-Index: 14207

      The piRNA pathway plays an important role in maintaining genome stability in the germ line by silencing transposable elements (TEs) from fly to mammals. As a highly conserved piRNA pathway component, Piwi is widely expressed in both germ cells and somatic cells in the Drosophila ovary and is required for piRNA production in both cell types. In addition to its known role in somatic cap cells to maintain germline stem cells (GSCs), this study has demonstrated that Piwi has novel functions ...

      Known for Drosophila Ovary | Germ Cells | Cell Lineage | Differentiation Piwi | Pirna Pathway
      KOL-Index: 14171

      Hepatocellular carcinoma related protein 1 (HCRP1), which is essential for internalization and degradation of ubiquitinated membrane receptors, is downregulated in several tumors and strongly affects the outcomes of cancer patients. It is reported the expression of HCRP1 is inversely related to epidermal growth factor receptor (EGFR) in breast cancer and lead to resistance to cetuximab in ovarian cancer. However, its exact mechanism in the progression of Hepatocellular carcinoma (HCC) ...

      Known for Hcrp1 Downregulation | Hepatocellular Carcinoma | Cell Migration | Expression Regulation | Mesenchymal Transition
      KOL-Index: 14126

      BACKGROUND AND AIMS: Golgi protein 73 (GP73) as a potential serum marker for hepatocellular carcinoma (HCC) has not been validated in large cohort studies. Furthermore, its significance in the assessment of tumour recurrence after HCC resection remains unknown. The aim of this study was to determine the value of serum GP73 in the diagnosis of HCC.

      METHODS: Serum GP73 and alpha-fetoprotein (AFP) were compared in a total of 4217 human subjects in this multicentre study, including 1690 ...

      Known for Patients Hcc | Golgi Protein | Serum Gp73 | Tumor Carcinoma | Specificity Afp

      Key People For Breast Cancer

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      Hui Hui Li:Expert Impact

      Concepts for whichHui Hui Lihas direct influence:Breast cancer,  Lung cancer,  Gastric cancer,  Hepatocellular carcinoma.

      Hui Hui Li:KOL impact

      Concepts related to the work of other authors for whichfor which Hui Hui Li has influence:Hepatocellular carcinoma,  Breast cancer,  Oxidative stress,  Type 2 diabetes,  Gene expression,  Photocatalytic activity,  Cell proliferation.



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      Faculty of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8572, Japan. | Shanghai Institute of Materia Medica Chinese Academy of Sciences, Shanghai, 201203 China | Key Laboratory of Engine Health Monitori

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