Andrew John Mallett: Influence Statistics

Andrew John Mallett

Andrew John Mallett

Institute for Molecular Bioscience (IMB), The University of Queensland, Brisbane, Queensland, Australia | College of Medicine, James Cook University, Townsville, Queensland, ...

Andrew John Mallett: Expert Impact

Concepts for which Andrew John Mallett has direct influence: Kidney disease , Genomic testing , Chronic kidney disease , Polycystic kidney , Autosomal dominant , Fibrillary glomerulonephritis , Pathogenic variants .

Andrew John Mallett: KOL impact

Concepts related to the work of other authors for which for which Andrew John Mallett has influence: Kidney disease , Genetic testing , Alport syndrome , Autosomal dominant , Exome sequencing , Fibrillary glomerulonephritis , Pluripotent stem cells .

KOL Resume for Andrew John Mallett

Year
2022

Institute for Molecular Bioscience (IMB), The University of Queensland, Brisbane, Queensland, Australia

2021

Department of Renal Medicine, Townsville University Hospital, Douglas, QLD, Australia

2020

Faculty of Medicine, The University of Queensland, Brisbane, QLD Australia

2019

Murdoch Children’s Research Institute, Melbourne, Victoria, Australia

2018

Faculty of Medicine, University of Queensland, Brisbane, QLD 4072, Australia

2017

School of Medicine The University of Queensland Brisbane Queensland Australia

2016

Royal Brisbane and Women's Hospital, Brisbane, QLD

Centre for Rare Diseases Research, Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia.

2015

Centre for Kidney Disease Research, Centre for Chronic Disease and CKD, School of Medicine and Centre for Rare Diseases Research, Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia

2014

Department of Renal Medicine, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia

2011

Department of Obstetric Medicine, Royal Brisbane and Women's Hospital, Butterfield Street, Herston, Brisbane, Queensland, 4029, Australia

Prominent publications by Andrew John Mallett

KOL-Index: 8816 . BACKGROUND: There are an established and growing number of Mendelian genetic causes for chronic kidney disease (CKD) in adults, though estimates of prevalence have been speculative. The CKD Queensland (CKD.QLD) registry enables partial clarification of this through the study of adults with CKD receiving nephrology care throughout Queensland, Australia. METHODS: Data from the first 2,935 ...
Known for Chronic Kidney Disease | Ckd Adults | Genetic Renal | Kidney Failure
KOL-Index: 8383 . BACKGROUND/AIM: This study aimed to report the clinical characteristics and outcomes of Australian patients treated with eculizumab for atypical haemolytic uraemic syndrome (aHUS). METHODS: A retrospective cohort study was undertaken of all patients in Australia treated with eculizumab provided in a compassionate access programme for a clinical diagnosis of aHUS using prospectively ...
Known for Eculizumab Treatment | Ahus Patients | Median Duration | Kidney Transplantation
KOL-Index: 6741 . AIM: This study aimed to identify consumer perspectives on topics and outcomes to integrate in the Kidney Health Australia Caring for Australasians with Renal Impairment (KHA-CARI) clinical practice guidelines on autosomal-dominant polycystic kidney disease (ADPKD). METHODS: A workshop involving three concurrent focus groups with 18 consumers (patients with ADPKD (n = 15), caregivers ...
Known for Autosomal Dominant | Health Professionals | Kidney Disease | Practice Guidelines
KOL-Index: 6073 . Inherited kidney disease encompasses a broad range of disorders, with both multiple genes contributing to specific phenotypes and single gene defects having multiple clinical presentations. Advances in sequencing capacity may allow a genetic diagnosis for familial renal disease, by testing the increasing number of known causative genes. However, there has been limited translation of ...
Known for Kidney Disease | Genetic Diagnosis | Humans Infant Infant | Causative Genes
KOL-Index: 6026 . BACKGROUND: Fibrillary glomerulonephritis (FGN) and immunotactoid glomerulopathy (IG) are uncommon and characterised by non-amyloid fibrillary glomerular deposits. The aim of this study was to investigate characteristics and outcomes of patients undergoing renal replacement therapy (RRT) for end-stage kidney disease (ESKD) secondary to FGN and IG. METHODS: All ESKD patients who commenced ...
Known for Fibrillary Glomerulonephritis | Patients Fgn | Kidney Disease | Renal Dialysis
KOL-Index: 5512 . Despite the increasing diagnostic rate of genomic sequencing, the genetic basis of more than 50% of heritable kidney disease remains unresolved. Kidney organoids differentiated from induced pluripotent stem cells (iPSCs) of individuals affected by inherited renal disease represent a potential, but unvalidated, platform for the functional validation of novel gene variants and investigation ...
Known for Kidney Organoids | Epithelial Cells | Renal Disease | Pluripotent Stem
KOL-Index: 5510 . BACKGROUND: Alport syndrome is a rare inheritable renal disease. Clinical outcomes for patients progressing to end-stage kidney disease (ESKD) are not well described. METHODS: This study aimed to investigate the characteristics and clinical outcomes of patients from Australia and New Zealand commencing renal replacement therapy (RRT) for ESKD due to Alport syndrome between 1965 and 1995 ...
Known for Alport Syndrome | Kidney Disease | Patient Survival | Transplant Outcomes
KOL-Index: 5340 . Tubulointerstitial kidney disease is an important cause of progressive renal failure whose aetiology is incompletely understood. We analysed a large pedigree with maternally inherited tubulointerstitial kidney disease and identified a homoplasmic substitution in the control region of the mitochondrial genome (m.547A>T). While mutations in mtDNA coding sequence are a well recognised cause ...
Known for Mitochondrial Dna | Kidney Disease | Control Region | Patient Fibroblasts
KOL-Index: 5161 . BACKGROUND: Primary distal renal tubular acidosis (dRTA) is a rare disorder, and we aimed to gather data on treatment and long-term outcome. METHODS: We contacted paediatric and adult nephrologists through European professional organizations. Responding clinicians entered demographic, biochemical, genetic and clinical data in an online form. RESULTS: Adequate data were collected on 340 ...
Known for Renal Tubular | Primary Distal | Ckd Stage | Adequate Metabolic Control
KOL-Index: 4981 . Monoallelic mutations of DNAJB11 were recently described in seven pedigrees with atypical clinical presentations of autosomal dominant polycystic kidney disease. DNAJB11 encodes one of the main cofactors of the endoplasmic reticulum chaperon BiP, a heat-shock protein required for efficient protein folding and trafficking. Here we conducted an international collaborative study to better ...
Known for Kidney Disease | Pathogenic Variants | Renal Cysts | Precise Diagnosis
KOL-Index: 4777 . PurposeWidespread, quality genomics education for health professionals is required to create a competent genomic workforce. A lack of standards for reporting genomics education and evaluation limits the evidence base for replication and comparison. We therefore undertook a consensus process to develop a recommended minimum set of information to support consistent reporting of design, ...
Known for Genomics Education | Item Standards | Health Professionals | Evaluation Reporting
KOL-Index: 4481 . Primary cilia are specialized sensory organelles that protrude from the apical surface of most cell types. During the past 2 decades, they have been found to play important roles in tissue development and signal transduction, with mutations in ciliary-associated proteins resulting in a group of diseases collectively known as ciliopathies. Many of these mutations manifest as renal ...
Known for Kidney Diseases | Renal Ciliopathies | Ciliary Proteins | Primary Cilia
KOL-Index: 4398 . Genome-wide association studies (GWASs) of medication use may contribute to understanding of disease etiology, could generate new leads relevant for drug discovery and can be used to quantify future risk of medication taking. Here, we conduct GWASs of self-reported medication use from 23 medication categories in approximately 320,000 individuals from the UK Biobank. A total of 505 ...
Known for Uk Biobank | Genome Wide | Biological Mechanism | Genetic Loci
KOL-Index: 4105 . Introduction: Genomic testing is becoming widely available as a diagnostic tool, although widespread implementation is not yet established in nephrology. Methods: An anonymous electronic survey was administered to investigate experience and confidence with genomic tests, perceived clinical utility of genomic services, preferences for service delivery models, and readiness for ...
Known for Clinical Genomics | Genomic Testing | Urgently Required | Survey Administered
KOL-Index: 3465 . BackgroundThe Australian Institute of Health and Welfare’s first report into acute kidney injury demonstrated a significant increase in the incidence of acute-tubulo interstitial nephritis, the ICD-10 code representing both acute interstitial nephritis and pyelonephritis, in women aged less than 55 years. In contrast, recent case series have reported rising rates of drug induced acute ...
Known for Acute Interstitial Nephritis | Renal Biopsy | Institute Health | Kidney Injury

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Institute for Molecular Bioscience (IMB), The University of Queensland, Brisbane, Queensland, Australia | College of Medicine, James Cook University, Townsville, Queensland, Australia | KidGen Collaborative, Australian Genomics Health Alliance, Melbo