Prominent publications by Emmilia Hodak

KOL Index score: 15529

BACKGROUND: The coexistence of mycosis fungoides, a peripheral T-cell lymphoma, and B-cell malignancies or Hodgkin's lymphoma in the same patient is unusual. Most descriptions are isolated case reports and case series are strikingly sparse.

OBJECTIVES: To detect cases of mycosis fungoides associated with B-cell malignancies or Hodgkin's lymphoma and to analyse the characteristics of and the interplay between the lymphoproliferative neoplasms.

METHODS: Patients with mycosis fungoides who ...

Also Ranks for: Mycosis Fungoides |  cell lymphoma |  chronic lymphocytic leukaemia |  skin neoplasms |  malignancies hodgkin
KOL Index score: 13140

BACKGROUND: Mycosis fungoides (MF) is an epidermotropic cutaneous T-cell lymphoma in which the tumor cells express a mature T-helper memory phenotype, ie, CD3(+), CD4(+), CD8(-), CD45RO(+), with a T-cell receptor (TCR) of the alpha/beta heterodimer. A minority of patients have an unusual immunohistochemical profile consisting of a CD4(-), CD8(+) mature T-cell phenotype. An aberrant CD4/CD8 double-negative (DN) immunophenotype in patients with early MF has rarely been ...

Also Ranks for: Cell Lymphoma |  cd4 cd8 |  mycosis fungoides |  early mf |  epidermotropic cutaneous
KOL Index score: 12641

BACKGROUND: An immunogenetic mechanism has been suggested to play a role in the pathogenesis of mycosis fungoides (MF). While results of studies on HLA class I associations haveproved inconsistent, two previous studies showed that certain HLA class II alleles were significantly increased among North American caucasian patients with MF: HLA-DRB1*11 and DQB1*03.

OBJECTIVES: To investigate the possible HLA class I and class II associations with MF among Jewish patients.

METHODS: The patient ...

Also Ranks for: Hla Class |  mycosis fungoides |  jewish patients |  dq antigens |  drb1 chains
KOL Index score: 12486

BACKGROUND: Erysipelas and cellulitis (hereafter referred to as 'cellulitis') are common bacterial skin infections usually affecting the lower extremities. Despite their burden of morbidity, the evidence for different prevention strategies is unclear.

OBJECTIVES: To assess the beneficial and adverse effects of antibiotic prophylaxis or other prophylactic interventions for the prevention of recurrent episodes of cellulitis in adults aged over 16.

SEARCH METHODS: We searched the following ...

Also Ranks for: Cellulitis Treatment |  randomized controlled trials |  antibiotic prophylaxis |  recurrent episodes |  placebo adverse
KOL Index score: 11459

BACKGROUND: Dermoscopy is a noninvasive technique for the diagnosis of skin lesions. Its accuracy for basal cell carcinoma (BCC) has not been systematically studied.

OBJECTIVE: We sought to systematically investigate the accuracy of dermoscopy for the diagnosis of BCC compared with examination with the naked eye.

METHODS: A systematic review of studies reporting the accuracy of naked eye examination and dermoscopy for the diagnosis of BCC was conducted. A meta-analysis for sensitivity ...

Also Ranks for: Basal Cell Carcinoma |  dermoscopy diagnosis |  sensitivity specificity |  naked eye examination |  skin lesions
KOL Index score: 11223

BACKGROUND: Rituximab is increasingly being appreciated as a remarkably effective treatment for pemphigus, mostly concomitantly with other immunosuppressive medications. The majority of studies have used a single cycle of rituximab with the same dosage as approved for the treatment of lymphomas, ie, 375 mg/m(2) weekly × 4 weeks. Rituximab is also approved for the treatment of rheumatoid arthritis, with a different dosing regimen: 1000 mg × 2, days 1 and 15.

OBJECTIVE: We aimed to assess ...

Also Ranks for: Pemphigus Patients |  rituximab treatment |  rheumatoid arthritis |  antibodies monoclonal |  single cycle
KOL Index score: 10869

Primary cutaneous CD30(+) lymphoproliferative disorders (CD30(+) LPDs) are the second most common form of cutaneous T-cell lymphomas and include lymphomatoid papulosis and primary cutaneous anaplastic large-cell lymphoma. Despite the anaplastic cytomorphology of tumor cells that suggest an aggressive course, CD30(+) LPDs are characterized by an excellent prognosis. Although a broad spectrum of therapeutic strategies has been reported, these have been limited mostly to small retrospective ...

Also Ranks for: Cutaneous Cd30 |  lymphomatoid papulosis |  lymphoproliferative disorders |  anaplastic large |  cell lymphoma
KOL Index score: 10812

Ligand-mediated activation of the insulin-like growth factor 1 (IGF-1) receptor is critical for epidermal keratinocyte proliferation in vitro, and its expression in normal and psoriatic epidermis suggests that it might regulate keratinocyte proliferation in vivo. In this study, we used a monoclonal antibody (alpha-IR3) that binds to the alpha-chain of this receptor to study its expression (i) in other epithelial cell types in human skin and (ii) in growth-activated epidermis associated ...

Also Ranks for: Epidermal Hyperplasia |  increased expression |  skin appendages |  epithelial cells |  1 receptor
KOL Index score: 10606

BACKGROUND: Patients with psoriasis on biologic therapies and a history of viral hepatitis carry a risk for reactivation.

OBJECTIVE: We evaluated safety of biologic therapies in psoriasis patients seropositive for hepatitis B or C viruses (HBV, HCV).

METHODS: A retrospective cohort study design was used. Clinical and laboratory data for 30 patients undergoing biologic therapy who were seropositive for HBV or HCV were evaluated. Next, a systematic review was performed. Primary outcomes ...

Also Ranks for: Biologic Therapies |  virus reactivation |  patients psoriasis |  retrospective cohort study |  hcv infection
KOL Index score: 9436

Psoriasis is characterized by alterations in both the epidermis and dermis of the skin. Epidermal keratinocytes display marked proliferative activation and differentiate along an "alternate" or "regenerative" pathway, while the dermis becomes infiltrated with leukocytes, particularly interleukin 2 (IL-2) receptor-bearing "activated" T cells. Psoralens, administered by the oral route, have therapeutic effects in psoriasis when photochemically activated by ultraviolet A light (PUVA ...

Also Ranks for: Puva Therapy |  psoriasis skin |  epidermis dermis |  therapeutic effects |  lymphocyte activation
KOL Index score: 9081

BackgroundBullous pemphigoid (BP) is the most common autoimmune blistering skin disease worldwide. Systemic corticosteroids are considered the mainstay of therapy; however, they may cause significant adverse effects and treatment failures, so additional therapeutic modalities with better safety profiles are required. Rituximab and omalizumab are novel biologic agents administered in recent years for the treatment of BP, yet data regarding their use in the disease are limited.ObjectiveOur ...

Also Ranks for: Bullous Pemphigoid |  omalizumab treatment |  systemic corticosteroids |  recurrence rituximab |  disease control
KOL Index score: 9004

BACKGROUND: Drug survival is defined as the time period of treatment with a certain drug until its cessation. The role of previous exposure to traditional systemic treatments in biologic survival is still unknown.

OBJECTIVE: To investigate the drug survival rates of biologic treatments in patients with psoriasis and to identify predictor factors.

METHODS: Survival analysis was performed on patients with severe psoriasis who received adalimumab, infliximab, etanercept, and ustekinumab for ...

Also Ranks for: Drug Survival |  psoriasis patients |  biologic treatments |  clalit health services |  psoriatic arthritis
KOL Index score: 8984

In many neoplasms, the finding p53 immunoreactivity correlates with striking cytologic atypia, a high tumor cell proliferation rate, and poor prognosis. The literature regarding p53 and Ki-67 (a nuclear proliferation-associated antigen) immunoreactivity in Kaposi's sarcoma is limited. We aimed to: (1) evaluate the role of p53 in the development of Kaposi's sarcoma; (2) determine whether there is a correlation between p53 and Ki-67 protein expression; and (3) determine possible ...

Also Ranks for: Kaposi Sarcoma |  spindle cells |  expression p53 |  classic ks |  ki67 antigen

Key People For Mycosis Fungoides

Top KOLs in the world
Rein ********
mycosis fungoides cell lymphoma sézary syndrome
Eric * **********
mycosis fungoides sézary syndrome cell lymphoma
Sean * *********
mycosis fungoides sézary syndrome cell lymphoma
Lorenzo *******
mycosis fungoides cell lymphoma skin neoplasms
Günter ****
cutaneous lymphomas mycosis fungoides cell lymphoma
Robert ****** *******
extracorporeal photopheresis host disease mycosis fungoides

Emmilia Hodak:Expert Impact

Concepts for whichEmmilia Hodakhas direct influence:Mycosis fungoides,  Primary anetoderma,  Chlormethine gel,  Bullous pemphigoid,  Antiphospholipid antibodies,  Mycosis fungoides mf,  Patients mf,  Mf patients.

Emmilia Hodak:KOL impact

Concepts related to the work of other authors for whichfor which Emmilia Hodak has influence:Mycosis fungoides,  Pemphigus vulgaris,  Cell lymphoma,  Bullous pemphigoid,  Atopic dermatitis,  Sézary syndrome,  Brentuximab vedotin.



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Division of Dermatology, Rabin Medical Center – Beilinson Hospital, Petach Tikva, Israel | Division of Dermatology, Rabin Medical Center, Beilinson Hospital, Petah Tikvah, Israel | Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel |