• Disease
  • Bacterial
  • Bacterial Biofilm
  • Anand Kumar Deva

    Prominent publications by Anand Kumar Deva

    KOL Index score: 12264

    BACKGROUND: The association between breast implants and breast implant-associated anaplastic large cell lymphoma (ALCL) has been confirmed. Implant-related risk has been difficult to estimate to date due to incomplete datasets.

    METHODS: All cases in Australia and New Zealand were identified and analyzed. Textured implants reported in this group were subjected to surface area analysis. Sales data from three leading breast implant manufacturers (i.e., Mentor, Allergan, and Silimed) dating ...

    Also Ranks for: Breast Implant |  new zealand |  anaplastic large |  cell lymphoma |  alcl australia
    KOL Index score: 11157

    BACKGROUND: Capsular contracture remains the most common complication following breast augmentation surgery, and evidence suggests that bacterial biofilm on the implant surface is responsible. The authors investigated whether the interaction of bacterial biofilm with implants independently determines progression to capsule formation. They also studied the rate of bacterial growth and adhesion to implants.

    METHODS: Sixteen adult female pigs had 121 breast implants inserted. Sixty-six ...

    Also Ranks for: Bacterial Biofilm |  implant surface |  smooth textured |  staphylococcus epidermidis |  electron microscopy
    KOL Index score: 10928

    BACKGROUND: Bacteria/biofilm on breast implant surfaces has been implicated in capsular contracture and breast implant-associated anaplastic large-cell lymphoma (ALCL). Macrotextured breast implants have been shown to harbor more bacteria than smooth or microtextured implants. Recent reports also suggest that macrotextured implants are associated with a significantly higher incidence of breast implant-associated ALCL. Using techniques to reduce the number of bacteria around implants, ...

    Also Ranks for: Breast Implants |  defined steps |  14point plan |  capsular contracture |  minimize bacterial
    KOL Index score: 10828

    BACKGROUND: Hospital-associated infections cause considerable morbidity and mortality, and are expensive to treat. Organisms causing these infections can be sourced from the inanimate environment around a patient. Could the difficulty in eradicating these organisms from the environment be because they reside in dry surface biofilms?

    AIM: The intensive care unit (ICU) of a tertiary referral hospital was decommissioned and the opportunity to destructively sample clinical surfaces was taken ...

    Also Ranks for: Electron Microscopy |  environmental surfaces |  resistant bacteria |  dry surface biofilms |  confocal laser
    KOL Index score: 10301

    The pathogenesis of fibrous capsular contracture after augmentation mammaplasty is still debated. One hypothesis implicates low-grade bacterial infections as a cause. The presence of a staphylococcal biofilm in a patient with recurrent capsular contracture was previously reported. A comparative, prospective, blinded, clinical study of implants and capsules removed from patients with or without significant capsular contracture was conducted to investigate the association of biofilm ...

    Also Ranks for: Subclinical Infection |  breast implant |  patients capsular contracture |  electron microscopy |  coagulasenegative staphylococci
    KOL Index score: 10046

    BACKGROUND: With breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) now accepted as a unique (iatrogenic) subtype of ALCL directly associated with textured breast implants, we are now at a point where a sound epidemiologic profile and risk estimate are required. The aim of this article is to provide a comprehensive and up-to-date global review of the available epidemiologic data and literature relating to the incidence, risk, and prevalence of BIA-ALCL.

    METHODS: All ...

    Also Ranks for: Breast Implants |  large cell |  current risk |  bia alcl |  implant anaplastic
    KOL Index score: 9914

    The environment has been shown to be a source of pathogens causing infections in hospitalised patients. Incorporation of pathogens into biofilms, contaminating dry hospital surfaces, prolongs their survival and renders them tolerant to normal hospital cleaning and disinfection procedures. Currently there is no standard method for testing efficacy of detergents and disinfectants against biofilm formed on dry surfaces.

    AIM: The aim of this study was to develop a reproducible method of ...

    Also Ranks for: Surface Biofilm |  efficacy testing |  aureus dry |  vitro model |  scanning electron
    KOL Index score: 8902

    BACKGROUND: Capsular contracture remains the most common complication following augmentation mammaplasty. The infective hypothesis implicates subclinical infection with biofilm in its pathogenesis. The authors developed an in vivo model of subclinical infection and biofilm formation to further investigate this.

    METHODS: Adult female pigs underwent augmentation mammaplasty using miniature gel-filled implants. Staphylococcus epidermidis was inoculated into some of the periprosthetics as ...

    Also Ranks for: Capsular Contracture |  porcine model |  augmentation mammaplasty |  biofilm formation |  subclinical infection
    KOL Index score: 8528

    BackgroundPathological forms of TAR DNA-binding protein 43 (TDP-43) are present in motor neurons of almost all amyotrophic lateral sclerosis (ALS) patients, and mutations in TDP-43 are also present in ALS. Loss and gain of TDP-43 functions are implicated in pathogenesis, but the mechanisms are unclear. While the RNA functions of TDP-43 have been widely investigated, its DNA binding roles remain unclear. However, recent studies have implicated a role for TDP-43 in the DNA damage ...

    Also Ranks for: Dna Damage |  amyotrophic lateral |  tdp43 pathology |  motor neurons |  joining nhej
    KOL Index score: 8497

    Topical negative pressure has been demonstrated to improve graft take in a number of noncomparative studies. This study aimed to assess whether split-thickness skin graft take is improved qualitatively or quantitatively with topical negative pressure therapy compared with standard bolster dressings. A blinded, prospective, randomized trial was conducted of 22 adult inpatients of Liverpool Hospital between July of 2001 and July of 2002 who had wounds requiring skin grafting. After ...

    Also Ranks for: Skin Grafting |  negative pressure |  2 weeks |  process assessment |  wound size
    KOL Index score: 8383

    BACKGROUND: Dry hospital environments are contaminated with pathogenic bacteria in biofilms, which suggests that current cleaning practices and disinfectants are failing.

    AIM: To test the efficacy of sodium hypochlorite solution against Staphylococcus aureus dry-surface biofilms.

    METHODS: The Centers for Disease Control and Prevention Biofilm Reactor was adapted to create a dry-surface biofilm, containing 1.36 × 10(7)S. aureus/coupon, by alternating cycles of growth and dehydration over ...

    Also Ranks for: Surface Biofilms |  staphylococcus aureus |  infection control |  sodium hypochlorite |  microbial viability
    KOL Index score: 8264

    Almost 200 women worldwide have been diagnosed with breast implant-associated anaplastic large cell lymphoma (BIA-ALCL). The unique location and specific lymphoma type strongly suggest an etio-pathologic link between breast implants and BIA-ALCL. It is postulated that chronic inflammation via bacterial infection may be an etiological factor. BIA-ALCL resembles primary cutaneous ALCL (pcALCL) in morphology, activated T-cell phenotype, and indolent clinical course. Gene expression array ...

    Also Ranks for: Cell Lymphoma |  anaplastic large |  early events |  breast implants biaalcl |  chronic inflammation
    KOL Index score: 8160

    Background: Bacterial infection is a common and serious complication in orthopedic implants following traumatic injury, which is often associated with extensive soft tissue damage and contaminated wounds. Multidrug-resistant bacteria have been found in these infected wounds, especially in patients who have multi trauma and prolonged stay in intensive care units.Purpose: The objective of this study was to develop a coating on orthopedic implants that is effective against drug-resistant ...

    Also Ranks for: Selenium Nanoparticles |  staphylococcus aureus |  orthopedic implants |  antimicrobial activity |  implant coatings
    KOL Index score: 8041

    BACKGROUND: A recent association between breast implants and the development of anaplastic large-cell lymphoma (ALCL) has been observed. The purpose of this study was to identify whether bacterial biofilm is present in breast implant-associated ALCL and, if so, to compare the bacterial microbiome to nontumor capsule samples from breast implants with contracture.

    METHODS: Twenty-six breast implant-associated ALCL samples were analyzed for the presence of biofilm by real-time quantitative ...

    Also Ranks for: Bacterial Biofilm |  breast implant |  cell lymphoma |  electron microscopy |  nextgeneration sequencing


    Anand Kumar Deva: Influence Statistics

    Sample of concepts for which Anand Kumar Deva is among the top experts in the world.
    Concept World rank
    relating incidence #1
    eightwomen #1
    dsb grown #1
    cutaneous manifestations largecell #1
    commentary mrsa #1
    biofilm visually #1
    biofilm contaminating #1
    instillation mature biofilms #1
    gels breast #1
    silicone leachables particles #1
    molecular clinical evaluation #1
    aps largecell #1
    hcp dsb bacteria #1
    biofilm intensive #1
    patients bacterial biofilm #1
    20 cycles contamination #1
    cleaning depth gauges #1
    growth epidermidis biofilm #1
    discussing cutaneous #1
    transferred hba #1
    roughness contracture #1
    contamination filler #1
    pockets inoculated #1
    decrease capsular #1
    commentary vitro evaluation #1
    silimed #1
    irrigationparts #1
    july wounds #1
    atp protein residues #1
    biofilm infection implants #1
    subclinical biofilm infection #1
    alcl capsular contracture #1
    dsb protective gloves #1
    breast implants introduction #1
    transferred coupons #1
    implantassociated alcl #1

    Key People For Bacterial Biofilm

    Top KOLs in the world
    John William Costerton
    pseudomonas aeruginosa electron microscopy cell wall
    Philip Shook Stewart
    pseudomonas aeruginosa chronic wounds antimicrobial agents
    Paul Stoodley
    biofilm formation staphylococcus aureus pseudomonas aeruginosa
    Everett Peter Greenberg
    quorum sensing pseudomonas aeruginosa gene expression
    Michael C Givskov
    pseudomonas aeruginosa quorum sensing biofilm formation
    Matthew R Parsek
    pseudomonas aeruginosa quorum sensing biofilm formation

    Anand Kumar Deva:Expert Impact

    Concepts for whichAnand Kumar Devahas direct influence:Bacterial biofilm,  Breast implant,  Capsular contracture,  Breast implants,  Surgical instruments,  Nasal augmentation,  Cell lymphoma,  Large cell.

    Anand Kumar Deva:KOL impact

    Concepts related to the work of other authors for whichfor which Anand Kumar Deva has influence:Capsular contracture,  Breast implants,  Negative pressure,  Cell lymphoma,  Wound therapy,  Anaplastic large,  Biofilm formation.



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    Department of Plastic and Reconstructive Surgery, Macquarie University, Suite 301, Level 3, 2 Technology place, New South Wales 2109, Australia; Integrated Specialist Healthcare Education and Research Foundation, Miranda, New South Wales, 2228, Austr