Prominent publications by Eelco F M Wijdicks

KOL Index score: 15284

BACKGROUND: Anticoagulant-related hemorrhage occurs with an incidence of approximately 1%/patient-year in mechanical heart valve recipients. Intracranial hemorrhage poses a difficult clinical choice; continuing anticoagulation therapy may enlarge the volume of the hemorrhage, early reinstitution of anticoagulation therapy may predispose patients to recurrence, and reversal of anticoagulation therapy may place patients at risk for systemic embolization involving the brain. The risk of ...

Known for Intracranial Hemorrhage |  Anticoagulation Therapy |  Mechanical Heart Valves |  Patients Risk |  Atrial Fibrillation
KOL Index score: 13899

IMPORTANCE: Brain death is the irreversible cessation of function of the entire brain, and it is a medically and legally accepted mechanism of death in the United States and worldwide. Significant variability may exist in individual institutional policies regarding the determination of brain death. It is imperative that brain death be diagnosed accurately in every patient. The American Academy of Neurology (AAN) issued new guidelines in 2010 on the determination of brain ...

Known for Brain Death |  United States |  Apnea Testing |  Clinical Examination |  Hospital Policies
KOL Index score: 13177

OBJECTIVE: Impaired consciousness has been incorporated in prediction models that are used in the ICU. The Glasgow Coma Scale has value but is incomplete and cannot be assessed in intubated patients accurately. The Full Outline of UnResponsiveness score may be a better predictor of mortality in critically ill patients.

SETTING: Thirteen ICUs at five U.S. hospitals.

SUBJECTS: One thousand six hundred ninety-five consecutive unselected ICU admissions during a six-month period in ...

Known for Unresponsiveness Score |  Glasgow Coma |  Critically Patients |  Predicting Mortality |  Impaired Consciousness
KOL Index score: 12832

The natriuretic peptide system consists of atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide (CNP). The system is implicated in the control of body fluid homeostasis, causes natriuresis and diuresis (ANP and BNP), and regulates vascular tone (CNP). A reciprocal relationship between ANP and endothelin (ET) has been suggested, and earlier studies have documented a possible role of ET in cerebral vasospasm after aneurysmal subarachnoid ...

Known for Natriuretic Peptide |  Anp Bnp |  Cerebral Vasospasm |  Cnp Sah |  Aneurysmal Subarachnoid
KOL Index score: 12509

BACKGROUND: In accordance with the Uniform Determination of Death Act, guidelines for brain death determination are developed at an institutional level, potentially leading to variability of practice. We evaluated the differences in brain death guidelines in major US hospitals with a strong presence of neurology and neurosurgery to determine whether there was evidence of variation from the guidelines as put forth by the American Academy of Neurology (AAN).

METHODS: We requested the ...

Known for Death Determination |  Apnea Testing |  Ancillary Tests |  Topic Societies |  Guidelines Categories
KOL Index score: 12194

BACKGROUND AND PURPOSE: There are uncertainties surrounding the optimal management of patients with brain swelling after an ischemic stroke. Guidelines are needed on how to manage this major complication, how to provide the best comprehensive neurological and medical care, and how to best inform families facing complex decisions on surgical intervention in deteriorating patients. This scientific statement addresses the early approach to the patient with a swollen ischemic stroke in a ...

Known for Cerebellar Infarction |  Patients Decompressive Craniectomy |  Heart Association |  Level Consciousness |  Stroke Cerebral
KOL Index score: 11563

BACKGROUND: Clinical and radiologic predictors of cerebral infarction occurrence and location after aneurysmal subarachnoid hemorrhage have been seldom studied.

METHODS: We evaluated all patients admitted to our hospital with aneurysmal subarachnoid hemorrhage between 1998 and 2000. Cerebral infarction was defined as a new hypodensity located in a vascular distribution on computed tomography (CT) scan.

RESULTS: Fifty-seven of 143 patients (40%) developed a cerebral infarction. On ...

Known for Cerebral Infarction |  Aneurysmal Subarachnoid |  Sensitivity Specificity |  Transcranial Vasospasm |  Xray Computed Ultrasonography
KOL Index score: 11398

OBJECTIVE: Pulmonary complications challenge the medical management of patients who have sustained aneurysmal subarachnoid hemorrhage (SAH). We assessed the frequency and types of pulmonary complications after aneurysmal SAH and analyzed the impact of pulmonary complications on patient outcome.

METHODS: We reviewed the records of all patients with acute SAH treated at our institution between 1990 and 1997. Three hundred five consecutive patients with an aneurysmal hemorrhage source ...

Known for Pulmonary Complications |  Aneurysmal Subarachnoid |  Symptomatic Vasospasm |  Hemorrhage Sah |  Medical Management
KOL Index score: 11182

OBJECT: Predicting which patients with aneurysmal subarachnoid hemorrhage (SAH) will develop delayed ischemic neurological deficit (DIND) due to vasospasm remains subjective and unreliable. The authors analyzed the utility of a novel software-based technique to quantify hemorrhage volume in patients with Fisher Grade 3 aneurysmal SAH.

METHODS: Patients with aneurysmal SAH in whom a computerized tomography (CT) scan was performed within 72 hours of ictus and demonstrated Fisher Grade 3 ...

Known for Symptomatic Vasospasm |  Aneurysmal Subarachnoid |  Fisher Grade |  Volumetric Quantification |  Hemorrhage Volume
KOL Index score: 10929

15% of patients with spontaneous subarachnoid haemorrhage have normal cerebral angiograms; they fare better than patients with demonstrated aneurysms, though rebleeding and cerebral ischaemia can still occur. In patients with a normal angiogram and accumulation of blood in the cisterns around the midbrain--"perimesencephalic nonaneurysmal haemorrhage"--outcome is excellent. To test the hypothesis that rebleeding and disability in angiogram-negative subarachnoid haemorrhage might be ...

Known for Subarachnoid Haemorrhage |  Computed Tomography |  Negative Angiography |  Perimesencephalic Pattern |  Patients Angiogram
KOL Index score: 10846

OBJECTIVE: The classification of the comatose patient has been greatly improved with the use of coma scales. The Full Outline of Unresponsiveness score has emerged as an alternative to the Glasgow Coma Scale in that it incorporates essential information needed to assess the depth of coma. One set of patients for which the Full Outline of Unresponsiveness score could be particularly beneficial is those admitted to an intensive care unit, where approximately 30%-35% of all patients are ...

Known for Unresponsiveness Score |  Coma Scale |  Interobserver Agreement |  Critically Patients |  Intensive Unit
KOL Index score: 10424

PURPOSE: Our goal is to provide an overview of the current evidence about components of the evaluation and treatment of adults with acute ischemic stroke. The intended audience is physicians and other emergency healthcare providers who treat patients within the first 48 hours after stroke. In addition, information for healthcare policy makers is included.

METHODS: Members of the panel were appointed by the American Heart Association Stroke Council's Scientific Statement Oversight ...

Known for Ischemic Stroke |  Early Management |  Evidence Recommendations |  Statement Panel |  48 Hours
KOL Index score: 10423

OBJECTIVE: To evaluate the predictive value of neurologic prognostic indicators for patients treated with hypothermia after surviving cardiopulmonary arrest.

METHODS: Patients who survived cardiopulmonary arrest were prospectively collected from June 2006 to October 2009. Detailed neurologic examinations were performed. Serum neuron specific enolase (NSE) measurements, brain imaging findings, somatosensory evoked potentials, and electroencephalogram (EEG) results were recorded. EEG ...

Known for Neurologic Outcome |  Cardiac Arrest |  Patients Hypothermia |  Eeg Patterns |  Falsepositive Rate
KOL Index score: 10400

OBJECTIVE: To investigate the feasibility of intra-arterial thrombolysis in acute basilar artery thrombosis.

DESIGN: We reviewed a consecutive series of patients in whom intra-arterial thrombolysis was performed during the period from 1994 to 1996.

MATERIAL AND METHODS: Intra-arterial thrombolysis with urokinase was done in an attempt to recanalize the basilar artery in a series of nine patients with basilar artery thrombosis admitted to the neurologic intensive care unit. At the time of ...

Known for Basilar Artery |  Arterial Thrombolysis |  Patients Recanalization |  Complete Recovery |  Lockedin Syndrome


Eelco F M Wijdicks: Influence Statistics

Sample of concepts for which Eelco F M Wijdicks is among the top experts in the world.
Concept World rank
meningococcal tomography #1
cpm central pontine #1
sahca #1
perimesencephalic subarachnoid #1
surgical evacuation treatment #1
apnea tests patients #1
lung transplantation cim #1
syndrome cobb #1
pulmonary complications #1
thalamic hemorrhage cas #1
seizures cortical blindness #1
stroke onset peak #1
hospital mortality outline #1
delayed cardiogenic shock #1
logistic models outline #1
myoclonic heart #1
insidious sinusitis #1
intraarterial thrombolysis urokinase #1
brainstem respiration #1
larger initial volume #1
variability 5 categories #1
deterioration enlargement #1
solitary brainstem abscess #1
hospital aneurysmal sah #1
hemorrhagic brainstem #1
xanthochromia normal #1
brain death adults #1
eye motor #1
acute nontraumatic weakness #1
gbs ileus #1
cisternal hemorrhage #1
interrater agreement score #1
longest followup 16 #1
earlier death withdrawal #1
trainee confidence evaluation #1
humans neurology #1
status myoclonus #1
treatment coma #1
thalamus rupture #1
endarterectomy intracerebral hemorrhage #1
new management trends #1
3 aneurysmal #1
hemorrhage rate hemorrhages #1
imaging comatose survivors #1
score gcs #1
deterioration brain #1
catastrophic brain #1
accurate predictor outcome #1
acutely comatose patient #1
acute neurology chapter #1

Key People For Brain Death

Top KOLs in the world
Eelco F M Wijdicks
brain death subarachnoid hemorrhage cardiac arrest
David Matthew Greer
brain death cardiac arrest ischemic stroke
Panayiotis N Varelas
brain death status epilepticus subarachnoid hemorrhage
Sam David Shemie
brain death organ donation circulatory determination
Gary S Gronseth
practice parameter parkinson disease nerve biopsy
David K C Cooper
heart transplantation platelet aggregation brain death

Eelco F M Wijdicks:Expert Impact

Concepts for whichEelco F M Wijdickshas direct influence:Brain death,  Subarachnoid hemorrhage,  Cardiac arrest,  Pulmonary complications,  Neurologic complications,  Ischemic stroke,  Poor outcome,  Mechanical ventilation.

Eelco F M Wijdicks:KOL impact

Concepts related to the work of other authors for whichfor which Eelco F M Wijdicks has influence:Subarachnoid hemorrhage,  Brain death,  Cardiac arrest,  Ischemic stroke,  Bacterial meningitis,  Status epilepticus,  Cerebral vasospasm.



Is this your profile? manage_accounts Claim your profile content_copy Copy URL code Embed Link to your profile

Division of Neurocritical Care and Hospital Neurology, Mayo Clinic, Rochester, Minnesota, USA | From the Neurosciences Intensive Care Unit, Mayo Clinic, Rochester, MN. | Neurosciences Intensive Care Unit, Department of Neurology, Mayo Clinic Hospital

FREE Custom List