• Disease
  • Cell
  • Cell Carcinoma
  • Stacey E Mills

    Prominent publications by Stacey E Mills

    KOL Index score: 21263

    The distinction between chromophobe renal cell carcinoma, the granular cell variant of clear cell renal cell carcinoma, and renal oncocytoma is a common diagnostic dilemma. The usefulness of KIT, CD10, RCC, and RON in the differential diagnosis of these renal epithelial tumors was investigated. KIT was 100% positive in chromophobe renal cell carcinoma (11 of 11) and renal oncocytoma (12 of 12). The KIT staining pattern was identical in both tumor types, with cytoplasmic membrane ...

    Also Ranks for: Renal Cell |  tumor carcinoma |  neoplasm biomarkers |  oxyphilic antigens |  differential humans
    KOL Index score: 14566

    BACKGROUND: Undifferentiated carcinomas of the upper aerodigestive tract (UCUAT) occur most frequently within the nasopharynx and are most often associated with infection by Epstein-Barr virus (EBV) (WHO undifferentiated nonkeratinizing squamous cell carcinoma). An unusual group of aggressive carcinomas are characterized by translocations that involve Nuclear Protein in Testis (NUT), a novel gene on chromosome 15. In about two-thirds of cases, NUT is fused to BRD4 on chromosome 19. These ...

    Also Ranks for: Nut Rearrangement |  undifferentiated carcinomas |  upper aerodigestive |  situ hybridization |  immunohistochemistry ihc
    KOL Index score: 14043

    Morphologic mimicry among human malignant neoplasms is a well-known phenomenon in surgical pathology; both undifferentiated and "committed" neoplasms may exhibit this trait. One particularly common group of histologic simulants includes ductal carcinomas of the breasts, the cutaneous appendages, and the salivary glands. One hundred three tumors in this structural cluster were analyzed microscopically and immunohistologically to codify points of potential pathologic similarity and ...

    Also Ranks for: Salivary Glands |  gland carcinoma |  estrogen receptors |  carcinoembryonic antigen |  breast neoplasms
    KOL Index score: 13954

    Dysregulated expression of oncogenic types of E6 and E7 is necessary for human papillomavirus (HPV)-driven carcinogenesis. An HPV E6/E7 mRNA in situ hybridization (ISH) assay covering 18 common high-risk types ("HR-RISH," aka HR-HPV RNA18 ISH) has not been extensively studied in the anogenital tract or validated on automated technology. We herein compare HR-RISH to DNA polymerase chain reaction (PCR), p16 immunohistochemistry, and a previously available HPV DNA ISH assay in HPV-related ...

    Also Ranks for: Situ Hybridization |  messenger rna |  hpv e6 |  viral reproducibility |  p16 immunohistochemistry
    KOL Index score: 13617

    BACKGROUND: With the advent of the prostate specific antigen (PSA) assay, an increased detection rate of prostate carcinoma has ensued. This has been associated with a downward stage migration. In contrast, grade has shifted heavily toward moderate differentiation. The authors sought to test the hypothesis that such changes in grade in part may be because of trends among pathologists to upgrade similar specimens over time.

    METHODS: Two expert genitourinary pathologists regraded 23 ...

    Also Ranks for: Radical Prostatectomy |  prostate biopsy |  gleason scores |  10 years |  specimens 1989
    KOL Index score: 13355

    Large cell neuroendocrine carcinoma (LCNEC) is a high-grade neuroendocrine neoplasm first described in the lung and subsequently well documented in many other anatomic sites. It has only recently been recognized that LCNEC can also occasionally arise in the head and neck. The role of human papillomavirus (HPV), which is associated with some small cell carcinomas of the head and neck, has not been investigated for LCNEC. We sought to further characterize the histologic, immunophenotypic, ...

    Also Ranks for: Neuroendocrine Carcinoma |  head neck |  large cell |  sinonasal tract |  role hpv
    KOL Index score: 12586

    Oncogenic osteomalacia (OO) is a rare paraneoplastic syndrome of osteomalacia due to phosphate wasting. The phosphaturic mesenchymal tumor (mixed connective tissue variant) (PMTMCT) is an extremely rare, distinctive tumor that is frequently associated with OO. Despite its association with OO, many PMTMCTs go unrecognized because they are erroneously diagnosed as other mesenchymal tumors. Expression of fibroblast growth factor-23 (FGF-23), a recently described protein putatively ...

    Also Ranks for: Mesenchymal Tumors |  cases pmtmct |  expression fgf23 |  aged osteomalacia |  osteoidlike matrix
    KOL Index score: 12151

    Brefeldin A (BFA) induces the rapid redistribution of the Golgi complex into the endoplasmic reticulum (ER), causing the glycoproteins that are retained in the ER to be processed by Golgi enzymes. We have examined the effects of BFA on the synthesis of glycosphingolipids (GSL) to map the intracellular sites of GSL synthesis. In several cultured cell types, BFA inhibited the synthesis of the neutral GSL gangliotriaosylceramide (GA2) and monosialoganglioside GM2 and disialoganglioside GD2, ...

    Also Ranks for: Brefeldin Bfa |  glycosphingolipid synthesis |  gm2 gd2 |  endoplasmic reticulum |  golgi complex
    KOL Index score: 11970

    To more fully characterize the clinical and pathologic spectrum of a recently described tumor entity of the sinonasal tract characterized by loss of nuclear expression of SMARCB1 (INI1), we analyzed 39 SMARCB1-deficient sinonasal carcinomas collected from multiple medical centers. The tumors affected 23 males and 16 females with an age range of 19 to 89 years (median, 52). All patients presented with locally advanced disease (T3, n=5; T4, n=27) involving the sinuses (mainly ethmoid) with ...

    Also Ranks for: Sinonasal Carcinoma |  situ hybridization |  tumor cells |  biomarkers young adult |  nasal cavity
    KOL Index score: 11162

    Tumors exhibiting neuroectodermal differentiation occur throughout the body, and the diverse tissues of the head and neck give rise to a wide assortment of these neoplasms. Neuroectodermal neoplasms may be divided into lesions showing primarily epithelial differentiation (Group I, neuroendocrine carcinomas) and a more diverse group (Group II) of nonepithelial neoplasms. This article reviews these neuroectodermal tumors of the head and neck with emphasis on the neuroendocrine carcinomas ...

    Also Ranks for: Head Neck |  neuroectodermal neoplasms |  neuroendocrine carcinomas |  small cell |  atypical carcinoid
    KOL Index score: 10989

    The Gleason histologic score of prostatic adenocarcinoma in biopsy specimens (needle cores or transurethral chips) was compared with the Gleason score of corresponding radical prostatectomy specimens from 53 patients with localized prostatic carcinoma. The Gleason score assigned to the biopsy specimen was identical to that of the prostatectomy specimen in 51% of cases, was greater than that of the prostatectomy specimen in 4%, and was less than that of the prostatectomy specimen in 45%. ...

    Also Ranks for: Prostatectomy Specimen |  prostatic carcinoma |  gleason score |  primary tumor |  initial diagnosis
    KOL Index score: 10983

    Most prior studies of primary diagnosis in surgical pathology using whole slide imaging (WSI) versus microscopy have focused on specific organ systems or included relatively few cases. The objective of this study was to demonstrate that WSI is noninferior to microscopy for primary diagnosis in surgical pathology. A blinded randomized noninferiority study was conducted across the entire range of surgical pathology cases (biopsies and resections, including hematoxylin and eosin, ...

    Also Ranks for: Primary Diagnosis |  surgical pathology |  slide imaging |  reference standard |  hematoxylin eosin
    KOL Index score: 10939

    The Ewing sarcoma breakpoint region 1 (EWSR1) is translocated in many sarcomas. Recently, its rearrangement has been described in salivary gland hyalinizing clear cell carcinomas (HCCCs) and in a subset of soft tissue myoepitheliomas. This study examines the presence of the EWSR1 rearrangement in a variety of salivary gland lesions including classic myoepitheliomas and HCCCs. Using a tissue microarray and whole-mount sections, fluorescence in situ hybridization (FISH) was performed on a ...

    Also Ranks for: Salivary Gland |  ewsr1 rearrangement |  situ hybridization |  rna binding |  10 women


    Stacey E Mills: Influence Statistics

    Sample of concepts for which Stacey E Mills is among the top experts in the world.
    Concept World rank
    signetring cells #1
    epsteinbarr nut #1
    carcinoma terminal #1
    staging treatment policies #1
    wolffiantype epithelium #1
    clear cell tumor #1
    epididymislike inclusions #1
    verruca vulgaris larynx #1
    presence vacuolated areas #1
    p53 brca1 loci #1
    coats mullerian #1
    neuroectodermal neoplasms #1
    lcnk kscc #1
    oncocytomas 12 #1
    morphology concomitant reahs #1
    pelvis 14yearold #1
    pathologic stage staining #1
    clinicopathologic features scc #1
    typical serous carcinomas #1
    inclusions inguinal #1
    42 prostatectomy #1
    lung asian patient #1
    microcystic adnexal patient #1
    normal deferens #1
    grade nonintestinal #1
    chr chr cath #1
    area adenocarcinomas #1
    mullerian type epithelium #1
    gleason histologic grading #1
    cdx2 ck20 immunoreactivity #1
    reahs rare lesions #1
    cases pscc #1
    s100 synaptophysin #1
    melanoma alternative diagnoses #1
    inguinal hernial sacs #1
    uniform cuboid cells #1
    gleason histological score #1
    untreated metastatic cap #1
    aggressive papillary tumor #1
    monosialosyl lewis fh7 #1
    myriad neoplasms #1
    terminology neuroendocrine carcinomas #1
    mitotic figures background #1
    tubular snacs #1
    case myoepithelial carcinoma #1
    nonintestinal low #1
    inguinal hernia sacs #1
    14 onbs #1
    positive nonintestinal #1
    normal deferens epididymis #1

    Key People For Cell Carcinoma

    Top KOLs in the world
    Ahmedin M Jemal
    united states breast cancer addis ababa
    Rebecca L Siegel
    united states colorectal cancer incidence rates
    Freddie Ian Bray
    cancer incidence nordic countries mortality rates
    Jacques Ferlay
    cancer incidence global burden latin america
    Robert John Motzer
    germ cell advisory consultancy metastatic renal
    Robert Alan Figlin
    renal cell carcinoma lung cancer kidney neoplasms

    Stacey E Mills:Expert Impact

    Concepts for whichStacey E Millshas direct influence:Cell carcinoma,  Situ hybridization,  Fallopian tube,  Undifferentiated carcinoma,  Thyroid lesions,  Differential diagnosis,  Glandular inclusions,  Prostatectomy specimen.

    Stacey E Mills:KOL impact

    Concepts related to the work of other authors for whichfor which Stacey E Mills has influence:Cell carcinoma,  Prostate cancer,  Urinary bladder,  Salivary gland,  Situ hybridization,  Differential diagnosis,  Nasal cavity.



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    Department of Pathology. | Department of Pathology, University of Virginia, Charlottesville, VA. | Department of Pathology, University of Virginia, Charlottesville, VA | Department of Pathology, University of Virginia Health Science Center, Charlotte