• Disease
  • Thymidine
  • Thymidine Analogue
  • Thymidine Analogue Mutations
  • Manuella Bonmarchand

    Prominent publications by Manuella Bonmarchand

    KOL Index score: 8328

    OBJECTIVES: Mutations usually associated with zidovudine exposure have been observed in zidovudine-naive patients treated by stavudine in combination. These mutations were named thymidine analogue mutations (TAMs). This fact, combined with phenotypical and biochemical findings provided additional evidence for cross-resistance between zidovudine and stavudine. A recent genotypic study in naive patients receiving stavudine/didanosine combination showed emergence of TAMs and a ...

    Also Ranks for: Thymidine Analogue Mutations |  reverse transcriptase |  naive patients |  stavudine lamivudine |  antiretroviral therapy


    Manuella Bonmarchand: Influence Statistics

    Sample of concepts for which Manuella Bonmarchand is among the top experts in the world.
    Concept World rank
    emergence tams #19
    emergence thymidine #27

    Key People For Thymidine Analogue Mutations

    Top KOLs in the world
    Daniel R Kuritzkes
    antiretroviral therapy virologic failure south africa
    Victoria Anne Johnson
    drug resistance mutations resistance testing reverse transcriptase
    Douglas D Richman†
    antiretroviral therapy hiv infection human immunodeficiency virus
    Joseph J Eron
    antiretroviral therapy united states hiv infection
    Mark A Wainberg
    reverse transcriptase immunodeficiency virus resistance mutations
    Françoise Brun‐Vézinet
    virological response viral load resistance mutations

    Manuella Bonmarchand:Expert Impact

    Concepts for whichManuella Bonmarchandhas direct influence:Thymidine analogue mutations,  Stavudine lamivudine,  Viral drug therapy,  Thymidine analogue,  Analogue mutations,  Receiving stavudine,  Antiretroviralnaive patients,  Resistance mutations.

    Manuella Bonmarchand:KOL impact

    Concepts related to the work of other authors for whichfor which Manuella Bonmarchand has influence:Resistance mutations,  Virological failure,  Cd4 cell count,  Yxdd motif,  M184v mutation,  Salvage therapy,  Treatment resumption.



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    Departments of Virology, Infectious Diseases and Internal Medecine, Pitié-Salpêtrière Hospital, Paris, France