• Arthritis
  • Arthritis Kols

    Prominent publications by John Dario Londono

    KOL Index score: 12279

    BACKGROUND: Anticyclic citrullinated peptide (anti-CCP) antibodies are highly specific for the diagnosis of rheumatoid arthritis (RA). The clinical distinction between RA and psoriatic arthritis (PsA) is often difficult to establish; therefore, the presence of rheumatoid factor (RF) and anti-CCP antibodies could be useful. Seven percent to 40% of patients with longstanding psoriasis will develop PsA at some point. Therefore, it is important to study the positivity of these antibodies in ...

    Also Ranks for: Psa Patients |  psoriatic arthritis |  anti ccp |  citrullinated peptide
    KOL Index score: 11362

    OBJECTIVE: To investigate the role of HLA-B and HLA-DR genes as contributors to genetic susceptibility and clinical expression of the spondyloarthropathies (SpA) in the Mexican population.

    METHODS: The study included 172 patients with SpA (undifferentiated SpA 83, ankylosing spondylitis (AS) 64, and reactive arthritis 25) and 99 healthy controls. The HLA-B and HLA-DR alleles were detected by the polymerase chain reaction with sequence-specific primers technique. Patient assessment ...

    Also Ranks for: Mexican Patients |  hla b27 |  undifferentiated spa |  reactive arthritis |  ankylosing spondylitis
    KOL Index score: 11171

    OBJECTIVE: To evaluate the efficacy and safety of etoricoxib and indomethacin in the treatment of patients with acute gout.

    METHODS: A randomized, double-blind, active-comparator study was conducted at 42 sites. A total of 189 men and women (> or =18 years of age) who were experiencing an acute attack (< or =48 hours) of clinically diagnosed gout were treated for 8 days with etoricoxib, 120 mg/day (n = 103), or indomethacin, 50 mg 3 times a day (n = 86). The primary efficacy end point ...

    Also Ranks for: Acute Gout |  etoricoxib indomethacin |  efficacy safety |  study joint |  controlled trial
    KOL Index score: 9475

    OBJECTIVE: To determine the rate and factors associated with ankylosing spondylitis in a cohort of patients with undifferentiated spondyloarthritides (SpA).

    METHODS: 62 consecutive patients with undifferentiated SpA seen between 1998 and 1999 underwent clinical and imaging evaluations throughout follow up. The main outcome measure was a diagnosis of ankylosing spondylitis.

    RESULTS: 50 patients with peripheral arthritis (n = 35) and inflammatory back pain (n = 24) (26 male; mean (SD) age ...

    Also Ranks for: Ankylosing Spondylitis |  radiographic sacroiliitis |  undifferentiated spa |  peripheral arthritis |  low grade
    KOL Index score: 9355

    OBJECTIVES: To determine the agreement of scores on the original visual analog scale (VAS) or Likert scale of the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Functional Index (BASFI), and Dougados Functional Index (DFI) with scores on a numerical rating scale (NRS). To assess the reproducibility and responsiveness of the instruments with the original scale and NRS.

    METHODS: Five hundred thirty-six patients with ankylosing spondylitis from the ...

    Also Ranks for: Numerical Rating Scale |  basdai basfi |  illness spondylitis |  ankylosing surveys |  total scores
    KOL Index score: 8796

    OBJECTIVE: To investigate the role of HSP70 genes as contributors to genetic susceptibility of the spondyloarthropathies (SpA) in the Mexican population.

    METHODS: The study included 150 patients with SpA (undifferentiated spondyloarthropathy (uSpA) 68, ankylosing spondylitis (AS) 60, and reactive arthritis 22) and 158 healthy controls. HSP70-1, HSP70-2 and HSP70-hom genotypes were analysed by the polymerase chain reaction-restriction fragment length polymorphism technique. Statistical ...

    Also Ranks for: Mexican Patients |  heat shock protein |  70 gene polymorphisms |  allele genotype |  hlab27 association
    KOL Index score: 8751

    OBJECTIVE: Human leucocyte antigen (HLA) B27 and HLA-B15 are associated with spondyloarthritis (SpA). Recent Assessment of SpondyloArthritis international Society (ASAS) criteria emphasise a distinction between SpA with axial and peripheral patterns. We analysed whether HLA-A, HLA-B and HLA-DRB1 alleles could associate with these patterns.

    METHODS: We studied 100 healthy individuals and 178 patients with SpA according to European Spondyloarthropathy Study Group (ESSG) criteria. Patients ...

    Also Ranks for: Patients Spa |  asas criteria |  hla b27 |  axial spondyloarthritis |  b15 antigen
    KOL Index score: 7898

    BACKGROUND: Recent consensus emphasizes the importance of studying individuals at risk for rheumatoid arthritis (pre-RA) and those with early RA (eRA). Periodontal tissues have been recently evaluated, but these studies are limited. To evaluate the periodontal condition, immunoglobulin (Ig)G subclasses against Porphyromonas gingivalis in individuals with pre-RA and eRA were compared with controls to establish an association between periodontal infection markers and rheumatic ...

    Also Ranks for: Periodontal Disease |  rheumatoid arthritis |  porphyromonas gingivalis |  creactive protein |  erythrocyte sedimentation rate
    KOL Index score: 7755

    To evaluate the role of tumor necrosis factor-alpha (TNF-alpha) gene as susceptibility marker for spondyloarthritis (SpA), two polymorphisms (-238 and -308 positions) were analyzed in 229 patients with SpA (113 with ankylosing spondylitis [AS], 92 with undifferentiated SpA [U-SpA], 24 with reactive arthritis), and 169 ethnically matched healthy control subjects. The HLA-B alleles were detected by PCR-SSP technique and the TNF-alpha polymorphism by PCR-RFLP. In comparison with healthy ...

    Also Ranks for: Necrosis Factor |  mexican patients |  promoter polymorphisms |  spa ankylosing spondylitis |  reactive arthritis
    KOL Index score: 7431

    Introducción Las enfermedades reumáticas son causa frecuente de discapacidad, deterioran la calidad de vida y causan alto gasto en salud. El modelo COPCORD se ha implementado universalmente para estimar su prevalencia. El objetivo es estimar la prevalencia de las enfermedades reumáticas en la población colombiana mayor de 18 años. Métodos Se realizó un estudio de prevalencia utilizando un método probabilístico de muestreo aleatorio estratificado en 3 etapas: selección de los sectores ...

    Also Ranks for: 18 Años |  rheumatoid arthritis |  rheumatic diseases |  low pain |  enfermedades reumáticas
    KOL Index score: 7058

    The objective of this study is to correlate the patient-driven tool Routine Assessment of Patient Index Data 3 (RAPID-3) with other common tools used in daily practice to measure disease activity in rheumatoid arthritis (RA).One hundred nineteen RA patients according to 1987 American College of Rheumatology criteria who consecutively attended a RA outpatient clinic between August and December 2015 were evaluated. Data was stored in an electronic form that included demographic ...

    Also Ranks for: Rheumatoid Arthritis |  colombian patients |  cdai sdai |  daily practice |  routine assessment
    KOL Index score: 6510

    INTRODUCTION: The prevalence of osteoporosis in premenopausal women along with associated risk factors has not been well elucidated. Recent studies have shown that poverty is a risk factor for osteoporosis.

    OBJECTIVE: To determine the prevalence of osteoporosis and its risk factors in a group of premenopausal women of poor economic background in Colombia.

    MATERIALS AND METHODS: The study comprised 1483 women between 35 and 53 years of age with at least one risk factor for osteoporosis. ...

    Also Ranks for: Osteoporosis Risk Factors |  ray absorptiometry |  dual energy |  women aged |  determine prevalence
    KOL Index score: 6466

    To evaluate the role of LMP (low molecular weight protein) genes as susceptibility markers for spondyloarthritis (SpA), LMP gene polymorphisms were analyzed in 223 Mexican patients with SpA (81 undifferentiated SpA [U-SpA], 117 with ankylosing spondylitis [AS], 25 with reactive arthritis) and in 139 ethnically matched healthy individuals. LMP genotypes were determined by polymerase chain reaction-restriction fragment length polymorphism. The LMP2 and LMP7 allele frequencies were similar ...

    Also Ranks for: Mexican Patients |  gene polymorphisms |  spondyloarthritis spa |  ankylosing spondylitis |  reactive arthritis


    John Dario Londono: Influence Statistics

    Sample of concepts for which John Dario Londono is among the top experts in the world.
    Concept World rank
    mtx metabolic pathway #1
    resolution tomography conclusion #1
    perioral wrinkles telangiectasia #1
    dhfrct snps #1
    toxicity colombian #1
    msc infusion treatment #1
    pathway colombian #1
    wharton rodnan #1
    colombian patients mtx #1
    toxicity colombian patients #1
    a1298c atic #1
    dhfrct #1
    mtx dhfrct #1
    snps mthfr c677t #1
    drug toxicity enzymes #1
    refractory scleroderma msc #1
    dkk1 disease activity #2
    biomarker functional disability #2
    biomarker joint destruction #2
    dickkopf 1 protein #2
    mdhaq dkk1 #2
    cdai 070 #2
    dkk1 disease #2
    functional status mdhaq #2
    rapid3 070 #2
    mdhaq dkk1 levels #2
    070 sdai #2
    aortitis sle #2
    mdhaq cdai #2
    colombia formal statistics #3
    distribution gbd #3
    studies preliminary snapshot #3
    uscrp il1α #3
    spas colombia #3
    il1α lbp #3
    19246 95 #3
    formal statistics incidence #3
    lbp hlab27 #3
    disability weight estimations #3
    study mthfr c677t #3
    classification dkk1 #3
    il1α crp #3
    colombian rea #3
    spas country #3
    preliminary snapshot spas #3
    5027671658 dalys #3
    alpha308 promoter #3
    colombian spa #3
    arthritis analyzed biomarkers #3
    lbp 003 #3

    Key People For Rheumatoid Arthritis

    Top KOLs in the world
    Paul Emery
    rheumatoid arthritis ankylosing spondylitis radiographic progression
    Josef Sebastian Smolen
    rheumatoid arthritis systemic lupus erythematosus radiographic progression
    James F Fries
    rheumatoid arthritis physical function systemic lupus erythematosus
    John Turner Sharp
    rheumatoid arthritis radiographic progression joint space width
    Frederick J Wolfe
    rheumatoid arthritis work disability rheumatic diseases
    Matthew H Liang
    rheumatoid arthritis systemic lupus erythematosus lyme disease

    John Dario Londono:Expert Impact

    Concepts for whichJohn Dario Londonohas direct influence:Rheumatoid arthritis,  Ankylosing spondylitis,  Colombian patients,  Systemic lupus erythematosus,  Rheumatic diseases,  Chikv infection,  Patients spa,  Latin america.

    John Dario Londono:KOL impact

    Concepts related to the work of other authors for whichfor which John Dario Londono has influence:Ankylosing spondylitis,  Rheumatoid arthritis,  Acute gout,  Heat shock protein,  Basdai basfi,  Systemic sclerosis,  Periodontal disease.



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    Grupo de Espondiloartropatías, Rheumatology Department, Universidad de La Sabana, Chía, Colombia | Spondyloarthropathies Research Group, Universidad de La Sabana, Chía, COL | Universidad de La Sabana | Spondyloarthropathy Group, Rheumatology Departme