• KOL
    • Chronic Kidney Disease
    • Rosanne E Jepson
    • Rosanne E Jepson: Influence Statistics

      Rosanne E Jepson

      Rosanne E Jepson

      Department of Clinical Science and Services, Royal Veterinary College, University of London, London, United Kingdom. | Department of Clinical Science and Services, Royal ...

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      Rosanne E Jepson:Expert Impact

      Concepts for whichRosanne E Jepsonhas direct influence:Chronic kidney disease,Acute kidney injury,Systemic hypertension,Serum creatinine,Renal function,Cats ckd,Systolic blood pressure,Renal fibrosis.

      Rosanne E Jepson:KOL impact

      Concepts related to the work of other authors for whichfor which Rosanne E Jepson has influence:Chronic kidney disease,Systemic hypertension,Cats ckd,Renal fibrosis,Symmetric dimethylarginine,Kidney injury,Serum creatinine.

      KOL Resume for Rosanne E Jepson

      Year
      2021

      Department of Clinical Science and Services, Royal Veterinary College, University of London, London, United Kingdom.

      2020

      Department of Clinical Science and Services, Royal Veterinary College, University of London, London, UK

      Clinical Science & Services, Royal Veterinary College, Hatfield, United Kingdom

      2019

      From Department of Clinical Sciences and Services, Royal Veterinary College, London, United Kingdom

      Clinical Science and Services, The Royal Veterinary College, AL97TA, Hatfield, UK

      2018

      Department of Clinical Science and Services, Royal Veterinary College, Hatfield, UK.

      2017

      Clinical Sciences and Services, Royal Veterinary College, Hawkshead Lane, Hatfield, Hertfordshire, AL9 7TA, UK

      Queen Mother Hospital for Animals Royal Veterinary College Brookmans Park Hatfield

      2016

      Department of Clinical Science and Services, Royal Veterinary College, University of London, Hatfield, Hertfordshire, UK

      2015

      Department of Clinical Science and Services, Royal Veterinary College, Hawkshead Lane, North Mymms, Hertfordshire AL9 7TA, UK.

      2014

      Clinical Sciences and Services, The Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Hertfordshire AL9 7TA, UK

      2013

      Department of Veterinary Clinical Sciences, Royal Veterinary College, NW1 0TU, London, England.

      2011

      Department of Veterinary Clinical Services, Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Herifordshire AL9 7TA, UK.

      2010

      Queen Mother Hospital for Animals, Royal Veterinary College, North Mymms, Hatfield, Hertfordshire AL9 7TA, England.

      2009

      Department of Veterinary Clinical Services, Royal Veterinary College, Hawkshead Lane, North Mymms, Nr Hatfield AL9 7TA, UK

      2008

      Department of Veterinary Basic Science, Camden, London, UK

      2007

      Departments of Veterinary Basic Science, Royal Veterinary College, Camden, London, UK

      2005

      Department of Clinical Veterinary Science, University of Bristol, Langford House, Bristol BS40 5DU, UK

      Sample of concepts for which Rosanne E Jepson is among the top experts in the world.
      Concept World rank
      pex dogs #2

      Prominent publications by Rosanne E Jepson

      KOL-Index: 11999

      BACKGROUND: Hypertension is a common problem in older cats, most often associated with chronic kidney disease (CKD). Cross-sectional studies have suggested that blood pressure in cats increases with age.

      HYPOTHESIS/OBJECTIVES: To determine whether blood pressure in cats increases with age and whether this occurs independently of the presence of CKD. To investigate risk factors for developing hypertension.

      ANIMALS/SUBJECTS: Two hundred and sixty-five cats with CKD and 133 healthy cats ≥9 ...

      Known for Blood Pressure | Healthy Cats | Chronic Kidney Disease | Ckd Risk Factors | Initial Evaluation
      KOL-Index: 11270

      BACKGROUND: Systemic hypertension is a common clinical problem, often occurring in association with renal disease in cats. Limited information is available to assess the effect of blood pressure and the treatment of hypertension on survival.

      HYPOTHESIS: That adequacy of blood pressure control is associated with the duration of survival in cats with systolic hypertension.

      ANIMALS: One hundred and forty-one client-owned cats with systolic hypertension.

      METHODS: Hypertensive cats were ...

      Known for Blood Pressure | Survival Cats | Treatment Hypertension | Amlodipine Besylate | Mm Hg
      KOL-Index: 11030

      Indirect blood pressure measurements were compared in 28 conscious cats using Doppler and oscillometric blood pressure-measuring devices. Ten cats were used to compare Doppler measurements between two examiners and 18 cats were used to compare Doppler and oscillometric measurements. The Doppler machine obtained systolic and diastolic blood pressure readings in 100% and 51% of attempts, respectively. With the oscillometric machine, systolic and diastolic blood pressure readings were ...

      Known for Blood Pressure | Conscious Cats | Oscillometric Machine | Measurements Doppler | Systolic Diastolic
      KOL-Index: 10523

      BACKGROUND: Chronic kidney disease (CKD) is a common comorbidity in cats with hypercalcemia, but whether CKD is a risk factor for hypercalcemia is unclear. Hypercalcemia often is diagnosed based on total calcium concentration (tCa), which tends to underestimate the ionized calcium concentration (iCa) in cats.

      OBJECTIVES: Assessment of the performance of tCa for the diagnosis of ionized hypercalcemia, and exploration of factors influencing the relationship between iCa and tCa. ...

      Known for Chronic Kidney Disease | Cats Hypercalcemia | Azotemic Ckd | Ionized Calcium | Retrospective Studies
      KOL-Index: 9017

      BACKGROUND: Chronic kidney disease (CKD) and hypertension have been associated with decreased bioavailability of nitric oxide (NO) and endothelial dysfunction. Increased concentrations of the endothelial nitric oxide synthase (eNOS) inhibitor asymmetric dimethylarginine (ADMA) are implicated.

      HYPOTHESIS: Plasma ADMA concentration is increased in cats with CKD and systemic hypertension corresponding to a decrease in total plasma nitrate/nitrite (NOx) availability. Decrease in systolic ...

      Known for Chronic Kidney Disease | Symmetric Dimethylarginine | Cats Ckd | Hypertensive Retinopathy | Nitric Oxide
      KOL-Index: 7407

      BACKGROUND: Chronic kidney disease (CKD) is a common condition in geriatric cats. Diagnosis is based on the development of persistent azotemia with inadequate urine concentrating ability. Biomarkers are sought for early identification.

      HYPOTHESIS: Clinical variables, urine concentrating ability, proteinuria, and N-acetyl-beta-D-glucosaminidase (NAG) index will be predictive of cats at risk of developing azotemia within 12 months.

      ANIMALS: Client-owned nonazotemic geriatric (>or=9 years) ...

      Known for Development Azotemia | Creatinine Concentration | 12 Months | Geriatric Cats | Urine Protein
      KOL-Index: 7259

      BACKGROUND: Numerous validated psychometric tools are available to assess impact of disease on a human's quality of life (QoL). To date, no psychometrically validated general health-related QoL tool exists for cats.

      HYPOTHESIS/OBJECTIVES: To develop and validate a tool for assessment of owner-perceived QoL in cats (CatQoL) and to use this tool to compare QoL between healthy cats and those with chronic kidney disease (CKD).

      ANIMALS/SUBJECTS: Total of 204 owners of young healthy cats (YH, ...

      Known for Chronic Kidney Disease | Healthy Cats | Life Qol | General Health | Hypothesis Objectives
      KOL-Index: 6967

      BACKGROUND: Hypomagnesemia is associated with increased mortality and renal function decline in humans with chronic kidney disease (CKD). Magnesium is furthermore inversely associated with fibroblast growth factor 23 (FGF23), an important prognostic factor in CKD in cats. However, the prognostic significance of plasma magnesium in cats with CKD is unknown.

      OBJECTIVES: To explore associations of plasma total magnesium concentration (tMg) with plasma FGF23 concentration, all-cause ...

      Known for Cats Ckd | Chronic Kidney Disease | Plasma Fgf23 | Fibroblast Growth Factor | Magnesium Concentration
      KOL-Index: 6149

      Chronic kidney disease (CKD) is a common medical condition of ageing cats. In most cases the underlying aetiology is unknown, but the most frequently reported pathological diagnosis is renal tubulointerstitial fibrosis. Renal fibrosis, characterised by extensive accumulation of extra-cellular matrix within the interstitium, is thought to be the final common pathway for all kidney diseases and is the pathological lesion best correlated with function in both humans and cats. As a ...

      Known for Renal Fibrosis | Chronic Kidney | Feline Ckd | Common Pathway | Diseases Cats
      KOL-Index: 5981

      BACKGROUND: In the absence of ocular target organ damage (ocular-TOD), diagnosis of hypertension is challenging in cats. Biomarkers would provide additional support for the diagnosis of hypertension.

      HYPOTHESIS: Vascular endothelial growth factor (VEGF), N-terminal probrain natriuretic peptide (NT-proBNP), cardiac troponin I (cTnI), and urine protein-to-creatinine ratio (UPC) are predictors of systemic hypertension, will be increased in cats with hypertension with or without ocular-TOD, ...

      Known for Cardiac Troponin | Cats Biomarkers | Natriuretic Peptide | Organ Damage | Hypertension Animals
      KOL-Index: 5757

      To describe the signalment, clinicopathological findings and outcome in dogs presenting with acute kidney injury (AKI) and skin lesions between November 2012 and March 2014, in whom cutaneous and renal glomerular vasculopathy (CRGV) was suspected and renal thrombotic microangiopathy (TMA) was histopathologically confirmed. The medical records of dogs with skin lesions and AKI, with histopathologically confirmed renal TMA, were retrospectively reviewed. Thirty dogs from across the UK were ...

      Known for Dogs Crgv | Glomerular Vasculopathy | Medical Records | Kidney Injury | Cutaneous Renal
      KOL-Index: 5596

      BACKGROUND: Role of renin-angiotensin aldosterone system (RAAS) in feline systemic hypertension is poorly understood.

      OBJECTIVES: Examine plasma renin activity (PRA) and plasma aldosterone concentrations (PAC) in normotensive and hypertensive cats with variable renal function and in response to antihypertensive therapy.

      ANIMALS: One hundred and ninety-six cats >9 years from first opinion practice.

      METHODS: PRA, PAC, and aldosterone-to-renin ratio (ARR) were evaluated in cats recruited ...

      Known for Hypertensive Cats | Amlodipine Besylate | Renin Activity | Role Raas | Angiotensin Aldosterone
      KOL-Index: 5527

      An update to the 2007 American College of Veterinary Internal Medicine (ACVIM) consensus statement on the identification, evaluation, and management of systemic hypertension in dogs and cats was presented at the 2017 ACVIM Forum in National Harbor, MD. The updated consensus statement is presented here. The consensus statement aims to provide guidance on appropriate diagnosis and treatment of hypertension in dogs and cats.

      Known for Systemic Hypertension | Dogs Cats | Acvim Consensus Statement | Pressure Blood | Veterinary Internal Medicine
      KOL-Index: 5228

      BACKGROUND: Glomerular filtration rate (GFR) estimation is the gold standard for assessment of renal function, although the clinical utility of this test is unclear.

      OBJECTIVES: To describe the clinical utility of GFR estimation in dogs.

      ANIMALS: Medical records of 132 dogs that had serum iohexol clearance measured between 2012 and 2017.

      METHODS: Iohexol clearance and clinical records were reviewed and submitting practices contacted to obtain outcome data. Dogs were classified into 4 ...

      Known for Glomerular Filtration | Clinical Utility | Gfr Estimation | Renal Disease | Iohexol Clearance
      KOL-Index: 4921

      BACKGROUND: Dietary phosphate restriction improves survival in cats with chronic kidney disease (CKD). However, feeding a phosphate-restricted diet may disrupt calcium homeostasis leading to hypercalcemia in some cats.

      OBJECTIVES: To identify risk factors associated with increasing plasma total calcium (tCa) concentration after transition to a phosphate-restricted diet and to explore its role in CKD-mineral and bone disorder (CKD-MBD) in cats.

      ANIMALS: Seventy-one geriatric (≥9 years) ...

      Known for Calcium Homeostasis | Chronic Kidney Disease | Cats Ckd | Restricted Diet | Phosphate Concentrations

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      Department of Clinical Science and Services, Royal Veterinary College, University of London, London, United Kingdom. | Department of Clinical Science and Services, Royal Veterinary College, University of London, London, UK. | Department of Clinical S

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