• Disease
  • Advanced
  • Advanced Cancer
  • Stein Kaasa

    Prominent publications by Stein Kaasa

    KOL Index score: 19455

    IMPORTANCE: Differences in utilization and costs of end-of-life care among developed countries are of considerable policy interest.

    OBJECTIVE: To compare site of death, health care utilization, and hospital expenditures in 7 countries: Belgium, Canada, England, Germany, the Netherlands, Norway, and the United States.

    DESIGN, SETTING, AND PARTICIPANTS: Retrospective cohort study using administrative and registry data from 2010. Participants were decedents older than 65 years who died with ...

    Also Ranks for: United States |  developed countries |  germany belgium |  acute hospitals |  canada england
    KOL Index score: 15724

    BACKGROUND: In order to make treatment decisions physicians should have knowledge about the relations between patient characteristics and drug disposition. Dose, route of administration, gender, age and renal function are reported to influence the serum concentrations of morphine, morphine-6-glucurnide (M6G) and morphine-3-glucuronide (M3G) during chronic treatment of cancer pain. These factors, however, are not evaluated in studies with a sample size sufficient to explore predictive ...

    Also Ranks for: Serum Concentrations |  drug monitoring |  morphine m6g |  renal function |  prospective survey
    KOL Index score: 15655

    The EORTC Study Group on Quality of Life has developed a modular system for assessing the quality of life of cancer patients in clinical trials composed of two basic elements: (1) a core quality of life questionnaire, the EORTC QLQ-C30, covering general aspects of health-related quality of life, and (2) additional disease- or treatment-specific questionnaire modules. Two international field studies were carried out to evaluate the practicality, reliability and validity of the core ...

    Also Ranks for: Eortc Qlq |  cancer clinical |  life questionnaire |  core quality |  patients performance status
    KOL Index score: 15467

    OBJECTIVE: This trial investigated the efficacy and long-term tolerability of intranasal fentanyl spray (INFS) 50 to 200 microg in the treatment of breakthrough pain in opioid-tolerant patients with cancer.

    METHODS: This Phase III, double-blind, randomized, placebo-controlled, crossover trial was conducted at pain centers, anesthesiology departments, palliative care units, and oncology clinics in Austria, Denmark, France, Germany, and Poland. Eligible patients were adults with cancer ...

    Also Ranks for: Breakthrough Pain |  intranasal fentanyl spray |  crossover trial |  effective dose |  patients cancer
    KOL Index score: 13910

    PURPOSE: The aim of this study was to define the scales and test the validity, reliability, and sensitivity of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ)-H&N35, a questionnaire designed to assess the quality of life of head and neck (H&N) cancer patients in conjunction with the general cancer-specific EORTC QLQ-C30.

    PATIENTS AND METHODS: Questionnaires were given to 500 H&N cancer patients from Norway, Sweden, and the ...

    Also Ranks for: Cancer Quality |  treatment life |  single items |  questionnaires patients |  european organization
    KOL Index score: 13350

    BACKGROUND: Sarcopenia is a defining feature of cancer cachexia associated with physical decline, poor quality of life and poor prognosis. Thus, maintaining muscle mass is an important aim of cachexia treatment. Many patients at risk for developing cachexia or with cachexia experience side effects of chemotherapy that might aggravate the development of cachexia. However, achieving tumor control might reverse the catabolic processes causing cachexia. There is limited knowledge about ...

    Also Ranks for: Muscle Mass |  palliative chemotherapy |  lung cancer |  sarcopenia baseline |  tumor control
    KOL Index score: 13342

    Context: Few studies and no international comparisons have examined the impact of multiple chronic conditions on populations using a comprehensive health-related quality of life (HRQL) questionnaire. Objective: The impact of common chronic conditions on HRQL among the general populations of eight countries was assessed. Design: Cross-sectional mail and interview surveys were conducted. Participants and setting: Sample representatives of the adult general population of eight countries ...

    Also Ranks for: Chronic Conditions |  disease comorbidity |  hypertension diabetes |  female humans life |  sf36 health
    KOL Index score: 13197

    Interpretation of health related quality of life (HRQOL) results in cancer patients is facilitated by knowledge of the levels of HRQOL in the general population. However, direct comparisons can be misleading unless age and gender are considered. We demonstrate the derivation of age- and gender-specific 'expected' values from population reference values by means of simple calculations. This survey included 3000 randomly selected Norwegians above 18 years of age who received the European ...

    Also Ranks for: Reference Data |  health quality life |  eortc qlq |  physical function |  expected scores
    KOL Index score: 12870

    To develop a framework for the definition and classification of cancer cachexia a panel of experts participated in a formal consensus process, including focus groups and two Delphi rounds. Cancer cachexia was defined as a multifactorial syndrome defined by an ongoing loss of skeletal muscle mass (with or without loss of fat mass) that cannot be fully reversed by conventional nutritional support and leads to progressive functional impairment. Its pathophysiology is characterised by a ...

    Also Ranks for: Cancer Cachexia |  international consensus |  definition classification |  weight loss |  reduced food intake
    KOL Index score: 12800

    Full integration of oncology and palliative care relies on the specific knowledge and skills of two modes of care: the tumour-directed approach, the main focus of which is on treating the disease; and the host-directed approach, which focuses on the patient with the disease. This Commission addresses how to combine these two paradigms to achieve the best outcome of patient care. Randomised clinical trials on integration of oncology and palliative care point to health gains: improved ...

    Also Ranks for: Palliative Oncology |  symptom control |  attitudes life |  health personnel attitude |  patient quality
    KOL Index score: 12683

    OBJECTIVES: Breakthrough cancer pain (BTP) represents a treatment challenge. Objectives were to examine the prevalence and characteristics of BTP in an international sample of patients with cancer, and to investigate the relationship between BTP and quality of life (QoL).

    METHODS: This was an observational cross-sectional multicentre study. Participating patients completed self-report questionnaires on a touch-screen laptop computer, including the Brief Pain Inventory, Alberta ...

    Also Ranks for: Cancer Pain |  patients btp |  international cohort |  quality life |  crosssectional studies
    KOL Index score: 12675

    PURPOSE: To investigate whether chemotherapy with etoposide and cisplatin (EP) is superior to cyclophosphamide, epirubicin, and vincristine (CEV) in small-cell lung cancer (SCLC).

    PATIENTS AND METHODS: A total of 436 eligible patients were randomized to chemotherapy with EP (n = 218) or CEV (n = 218). Patients were stratified according to extent of disease (limited disease [LD], n = 214; extensive disease [ED], n = 222). The EP group received five courses of etoposide 100 mg/m(2) ...

    Also Ranks for: Etoposide Regimen |  cell lung |  cev arm |  ld patients |  5 year
    KOL Index score: 12536

    PURPOSE: In advanced cancer, oncological treatment is influenced by performance status (PS); however, this has limitations. Biomarkers of systemic inflammation may have prognostic value in advanced cancer. The study compares key factors in prognosis (performance status, patient-reported outcomes; PRO) with an inflammation-based score (Glasgow Prognostic Score, mGPS). A new method of prognosis in advanced cancer (combining performance status and mGPS) is tested and then ...

    Also Ranks for: Advanced Cancer |  performance status |  clinicopathological factors |  mgps survival |  systemic inflammation


    Stein Kaasa: Influence Statistics

    Sample of concepts for which Stein Kaasa is among the top experts in the world.
    Concept World rank
    cachexia treatment #1
    analgesics performance status #1
    clinical guidelines combat #1
    selfreports sedation #1
    scores cognitive dysfunction #1
    international classification diseases11 #1
    algorithm diagnostic criteria #1
    depression terminally aged #1
    depression poor sleep #1
    chemotherapycourse outcomes #1
    content validity tools #1
    regard attitude #1
    opioids prospective studies #1
    prognostic validity relationship #1
    treatment mw #1
    rectal volume variations #1
    cachexia status #1
    adequate symptom control #1
    hospital ward unit #1
    validity cancer patients #1
    behavioural pain assessment #1
    consistency psychometric properties #1
    cancer patients analyses #1
    methadone week titration #1
    actigraphy awakenings #1
    opioid efficacy patients #1
    effects lent soma #1
    year fatigue questionnaire #1
    age treatment intent #1
    crossover chemotherapy etoposide #1
    additional diagnoses stage #1
    consultation types #1
    cancer practical guideline #1
    sd123men #1
    weight loss domains #1
    scores function #1
    palliative radiotherapy life #1
    kcal day protein #1
    morphine oxycodone methadone #1
    version international testing #1
    life scores study #1
    clinical impression dn4 #1
    analgesic effects corticosteroids #1
    saes sag strategy #1
    hunt pain #1
    cachexia guidelines #1
    spiritual qol carers #1
    sociology surveys #1
    icd11 patients #1
    cancer pain consensus #1

    Key People For Advanced Cancer

    Top KOLs in the world
    Eduardo D Eduardo
    advanced cancer spiritual pain symptom burden
    Stein Kaasa
    advanced cancer chronic pain quality life
    Irene Julie Higginson
    advanced cancer older people outcome measures
    Camilla Zimmermann
    advanced cancer early palliative attachment security
    Jennifer S Temel
    advanced cancer early palliative hospitalized patients
    Vicki Ann Jackson
    early palliative advanced cancer hospitalized patients

    Stein Kaasa:Expert Impact

    Concepts for whichStein Kaasahas direct influence:Advanced cancer,  Cancer pain,  Chronic pain,  Cancer cachexia,  Quality life,  Weight loss,  Serum concentrations,  Patients advanced cancer.

    Stein Kaasa:KOL impact

    Concepts related to the work of other authors for whichfor which Stein Kaasa has influence:Quality life,  Chronic pain,  Breast cancer,  Physical activity,  Weight loss,  Cell lung,  Mental health.



    Is this your profile? manage_accounts Claim your profile content_copy Copy URL code Embed Link to your profile

    European Palliative Care Research Centre (PRC), Department of Oncology, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Oslo, Norway. | Institute of Cancer Research and Molecular Medicine, Department of Medicine, Nor