Peter James Goadsby

Peter James Goadsby

Department Of Neurology, The Prince Henry Hospital, Little Bay, Nsw, 2036

Direct Impact

Concepts for which Peter James Goadsby has direct influence:

cluster headache
chronic migraine
trigeminocervical complex
visual snow
superior sagittal sinus
calcitonin gene-related peptide
hemicrania continua

External impact

Concepts related to the work of other authors for which Peter James Goadsby has influence:

cluster headache
premonitory symptoms
chronic migraine
calcitonin gene-related peptide
hepg2 cells
hemicrania continua
2 diabetes

Prominent publications by Peter James Goadsby

KOL-Index: 133 Migraine is a common, complex brain disorder whose biology is becoming better understood. Despite being the most disabling of the neurological disorders on a worldwide basis, headache disorders broadly, and migraine in particular, have poor research funding and a limited academic base. Given a modicum of investment, new targets, such as calcitonin gene-related peptide-based mechanisms, and ...

Migraine


[ PUBLICATION ]
KOL-Index: 126 Migraine pharmacology can currently be divided into medications for the acute treatment of migraine attacks and migraine preventive, or prophylactic, medications that aim to reduce the frequency and severity of the attacks. In this chapter, we review the current options for migraine treatment. A brief historical background is given for each medication along with a summary of the clinical ...
Known for
Migraine Medicines | Trials Led | Preventives Covered | Cgrp Receptor

Migraine


[ PUBLICATION ]
KOL-Index: 125 Migraine is a common, chronic, disorder that is typically characterized by recurrent disabling attacks of headache and accompanying symptoms, including aura. The aetiology is multifactorial with rare monogenic variants. Depression, epilepsy, stroke and myocardial infarction are comorbid diseases. Spreading depolarization probably causes aura and possibly also triggers trigeminal sensory ...
Known for
Moderate Severe Attacks | Depolarization | Analgesics | Cgrp Receptor Antagonists
KOL-Index: 101 Migraine is the second most disabling disorder across all age groups worldwide. Since 2018, two classes of drugs that inhibit the actions of calcitonin gene-related peptide (CGRP), which is implicated in migraine pathophysiology, have become available: gepants (CGRP receptor antagonists) and monoclonal antibodies directed against CGRP or its receptor. Despite phase 3 clinical trials and some ...
Known for
Therapies Gepants | Migraine Pharmacology | Peptide Cgrp
KOL-Index: 77 Migraine is a symptomatically heterogeneous condition, of which headache is just one manifestation. Migraine is a disorder of altered sensory thresholding, with hypersensitivity among sufferers to sensory input. Advances in functional neuroimaging have highlighted that several brain areas are involved even prior to pain onset. Clinically, patients can experience symptoms hours to days prior ...
Known for
Sufferers | Functional Neuroimaging | Disorders Chronic | Systems Migraine
KOL-Index: 73 Plaguing humans for more than two millennia, manifest on every continent studied, and with more than one billion patients having an attack in any year, migraine stands as the sixth most common cause of disability on the planet. The pathophysiology of migraine has emerged from a historical consideration of the "humors" through mid-20th century distraction of the now defunct Vascular Theory to ...
KOL-Index: 65 Introduction: Germline aryl hydrocarbon receptor-interacting protein (AIP) mutations are responsible for 15-30% of familial isolated pituitary adenomas (FIPAs). We report a FIPA kindred with a heterozygous deletion in AIP, aiming to highlight the indications and benefits of genetic screening, variability in clinical presentations, and management challenges in this setting. Patients: An ...
Known for
Kindred Pituitary | Germline Aip | Mri Microadenoma | Challenges Members
KOL-Index: 62 Migraine attacks can involve changes of appetite: while fasting or skipping meals are often reported triggers in susceptible individuals, hunger or food craving are reported in the premonitory phase. Over the last decade, there has been a growing interest and recognition of the importance of studying these overlapping fields of neuroscience, which has led to novel findings. The data suggest ...
Known for
Interaction Migraine | Meals Food | Understanding Phase | Craving Reported
KOL-Index: 62 Migraine is a common and disabling neurological disorder, with a significant socioeconomic burden. Its pathophysiology involves abnormalities in complex neuronal networks, interacting at different levels of the central and peripheral nervous system, resulting in the constellation of symptoms characteristic of a migraine attack. Management of migraine is individualised and often necessitates ...
Known for
Prevention Pathophysiology | Understanding Migraine
KOL-Index: 62 BACKGROUND: Indomethacin is a nonsteroidal anti-inflammatory drug whose mechanism of action in certain types of headache disorders remains unknown. The so-called indomethacin-responsive headache disorders consist of a group of conditions with a very different presentation that have a particularly good response to indomethacin. The response is so distinct as to be used in the definition of ...
Known for
Response Indomethacin | Hemicrania | Headaches Narrative

Department of Neurology, The Prince Henry Hospital, Little Bay, NSW, 2036

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