• Disease
  • Co2
  • Co2 Laser
  • Joshua E Lane

    Prominent publications by Joshua E Lane

    KOL Index score: 6767

    BACKGROUND: Acne scarring is a common manifestation that remains a therapeutic challenge to dermatologists, dermatologic surgeons, and plastic surgeons. Although multiple therapeutic modalities exist, treatment often remains inadequate. The use of high-concentration (95%) trichloroacetic acid (TCA) applied focally to atrophic acne scars has been described.

    OBJECTIVE: The current study confirms the utility of focal application of 95% TCA to acne scars in addition to a histologic ...

    Also Ranks for: Acne Scars |  trichloroacetic acid |  focal application |  therapeutic challenge |  wooden applicators
    KOL Index score: 5407

    Atopic dermatitis is a common diagnosis that presents a therapeutic challenge. Although multiple therapeutic modalities exist, there is no single monotherapy that has proven exceptional in ameliorating the symptoms of this disease. Current topical and systemic therapeutic options offer benefit but carry varying degrees of adverse effects that often limit their application. We present 3 patients with severe, recalcitrant atopic dermatitis successfully treated with omalizumab.

    Also Ranks for: Recalcitrant Atopic Dermatitis |  monoclonal antibodies |  atopic doseresponse relationship |  3 patients |  common diagnosis
    KOL Index score: 5366

    A number of chelating agents and some of their derivatives are as effective as, or superior to, benznidazole, the compound currently in clinical use, in the suppression of the reproduction of epimastigotes of Trypanosoma cruzi, the protozoa that causes Chagas' disease. All compounds were examined at a culture concentration of 5 micrograms/mL. The most effective compounds included N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine, sodium diethylamine-N-carbodithioate, ...

    Also Ranks for: Trypanosoma Cruzi |  chagas disease |  chelating agents |  superoxide dismutase |  compounds based
    KOL Index score: 5335

    OBJECTIVE: Keloids occur commonly after trauma to the skin, with ear piercing being a well-known inciting event. We surveyed 32 patients with keloids resulting from ear piercing, to examine a potential relationship between age of piercing and keloid formation.

    METHODS: A total of 32 consecutive patients completed a survey about ear-piercing and keloid formation. Fisher's exact test was used for data analysis.

    RESULTS: Fifty percent (n = 16) of surveyed patients developed a keloid after ...

    Also Ranks for: Ear Piercing |  keloid formation |  external female |  adolescent age |  occur commonly
    KOL Index score: 5190

    BACKGROUND: Pearly penile papules are angiofibromas found on the corona and sulcus of the glans penis. While these represent a benign condition, psychological and cosmetic concerns often prompt patients to seek therapeutic removal of these lesions. Multiple therapeutic modalities have been reported; however, use of CO2 laser has proven to be the most effective to date.

    OBJECTIVE: To demonstrate the efficacy of CO2 laser in treating pearly penile papules.

    METHODS: Case report.

    RESULTS: We ...

    Also Ranks for: Co2 Laser |  pearly penile papules |  successful treatment |  glans penis |  carbon dioxide
    KOL Index score: 5126

    BACKGROUND: The cellular angiofibroma is a benign mesenchymal neoplasm that clinically and histologically must be distinguished from biologically more aggressive lesions. It typically arises in women of late reproductive age and lends itself to cure by complete local excision. A report of an unusual case in a postmenopausal patient is presented.

    CASE: A 77-year-old woman presented with a painless vulvar mass that slowly enlarged over 3 years. Past history included a hysterectomy and ...

    Also Ranks for: Cellular Angiofibroma |  vulvar neoplasms |  mesenchymal lesions |  aggressive angiomyxoma |  stromal cells
    KOL Index score: 4886

    Traditional surgical treatment of nonmelanoma skin cancer includes excision with subsequent evaluation of surgical margins, either via frozen sections intraoperatively or after excision and closure. Accurate communication between surgeon and pathologist regarding the meaning of surgical margins should be confirmed. Recurrences of tumor growth may in part be attributed to asymmetrical tumor growth patterns with extension of tumor in an unanticipated direction. Mohs micrographic surgery is ...

    Also Ranks for: Surgical Margins |  nonmelanoma skin cancer |  micrographic surgery |  basal cell carcinoma |  frozen sections
    KOL Index score: 4659

    Erythema elevatum diutinum (EED) is a rare and chronic cutaneous leukocytoclastic vasculitis. It is predominantly seen on the extensor surfaces of the extremities. Although a specific cause is largely unknown, EED has been noted to occur in association with a wide variety of diseases. A 28-year-old man with systemic lupus erythematosus (SLE) and a 53-year-old woman with an overlap syndrome of rheumatoid arthritis and polymyositis are presented. Both patients developed EED in the setting ...

    Also Ranks for: Erythema Elevatum Diutinum |  connective tissue disease |  rheumatoid arthritis |  underlying conditions |  extensor surfaces
    KOL Index score: 4561

    In the southern and southeastern United States, the 9-banded armadillo is an important reservoir for Mycobacterium leprae, the causative agent of leprosy (Hansen's disease). Here, we describe a woman living in Georgia with borderline tuberculoid leprosy who worked for many years in a garden where armadillos burrowed or were buried. There was no history of foreign travel or known exposure to a person with leprosy. Treatment with 6 once-monthly combined doses of rifampin, ofloxacin, and ...

    Also Ranks for: Borderline Tuberculoid Leprosy |  armadillo exposure |  mycobacterium leprae |  causative agent |  foreign travel
    KOL Index score: 4217

    Acetaminophen is one of the most frequently used medications in the United States. While usual dosing of acetaminophen is considered harmless, both acute and chronic overdoses can be fatal. The majority of reported cases of chronic acetaminophen toxicity in adults occur in chronic alcohol abusers, patients taking P450-inducing medications, or following massive dosing. We describe a case of toxic hepatitis free of the aforementioned risk factors associated with chronic ingestion of ...

    Also Ranks for: Chronic Acetaminophen |  liver injury |  analgesics narcotic |  drug induced
    KOL Index score: 4118

    BACKGROUND: Extramedullary hematopoiesis is a well-documented manifestation of chronic myeloproliferative disorders, most commonly seen in chronic idiopathic myelofibrosis (agnogenic myeloid metaplasia), but rarely in chronic myelogenous leukemia. It typically occurs in the spleen and liver, but has also been described in skin. Microscopically, foci of extramedullary hematopoiesis consist of erythroid and myeloid precursors intermixed with megakaryocytes. The megakaryocytes may elaborate ...

    Also Ranks for: Sclerosing Extramedullary |  hematopoietic tumor |  chronic myelogenous |  publication aged biomarkers |  skin diseases
    KOL Index score: 3934

    Hereditary neuropathy with liability to pressure palsies (HNPP) is a recurrent disorder of the peripheral nervous system characterized by reversible episodes of sensorimotor deficits after neural compression injuries. Also known as tomaculous neuropathy, HNPP is further characterized ultrastructurally by multiple focal thickenings (tomacula) of peripheral myelin and has an autosomal dominant inheritance. The neuropathology of HNPP includes a partial deletion encoding the peripheral ...

    Also Ranks for: Pressure Palsies |  hereditary neuropathy |  compression neuropathies |  chromosome deletion |  sensory motor
    KOL Index score: 3861

    Paraneoplastic autoimmune multiorgan syndrome, also known as paraneoplastic pemphigus, has been observed only rarely among children. We describe a 10-year-old boy with typical clinical and histologic findings of paraneoplastic pemphigus associated with Castleman's disease. His disease was refractory to resection of the tumor and aggressive combination immunosuppressive therapies. The patient died 1 year after presentation, as a result of complications of bronchiolitis obliterans. This ...

    Also Ranks for: Paraneoplastic Pemphigus |  multiorgan syndrome |  bronchiolitis obliterans |  castleman disease |  fatal outcome


    Joshua E Lane: Influence Statistics

    Sample of concepts for which Joshua E Lane is among the top experts in the world.
    Concept World rank
    pennies immersion #2
    imaging gastric pennies #2
    utility radiographic examination #2
    tca atrophic #2
    gastric pennies #2
    pennies children #2
    hydrochloric acid gastric #2
    wooden applicators #2
    radiographic examination pennies #2
    earlier situ reaction #2
    pennies publication child #2
    children pennies #2
    gastric pennies children #2
    higher zinc composition #2
    pennies child #2
    southeast female humans #3
    literature paraneoplastic pemphigus #3
    source leprosy infection #3
    texas animals armadillos #3
    tca focally #3
    leprosy infection southeast #3
    eed patients eed #3
    treatment pearly #4
    lesion simple excision #4
    iron‐ chelating #4
    immersion hydrochloric acid #4
    iron‐ chelating agents #4
    protozoan heart reaction #5
    codes flagellar protein #5
    situ techniques dna #5
    dermatitis omalizumab #6
    texas southeast #7
    background pincer #8
    deep fascial layer #9
    tca acne #9
    177 sequence #9
    angiofibroma benign #9
    armadillos source #10
    keloids ear #10
    focally atrophic #10
    leprosy southeastern #11
    thermocautery #11
    favorable aesthetic outcomes #12
    labeling leprosy #12
    cheminform abstract inhibition #12
    common foreign objects #13
    cellular angiofibroma vulva #14
    neoplasms epidermodysplasia #14
    asymptomatic nodules #15
    trypanosoma epimastigotes #15

    Key People For Co2 Laser

    Top KOLs in the world
    R Rox Anderson
    photodynamic therapy laser treatment human skin
    M Stuart Strong
    co2 laser aerodigestive tract oral cavity
    John D B Featherstone
    dental enamel caries risk co2 laser
    Geza J Jako
    co2 laser aerodigestive tract labyrinthine fluids
    Daniel Fried
    dental enamel co2 laser selective removal
    Stanley M Shapshay
    yag laser subglottic stenosis retinoic acid

    Joshua E Lane:Expert Impact

    Concepts for whichJoshua E Lanehas direct influence:Co2 laser,  Pearly penile papules,  Trypanosoma cruzi,  Basal cell,  Brachioradial pruritus,  Acne scars,  Paraneoplastic pemphigus,  Epidermodysplasia verruciformis.

    Joshua E Lane:KOL impact

    Concepts related to the work of other authors for whichfor which Joshua E Lane has influence:Atopic dermatitis,  Trypanosoma cruzi,  Cellular angiofibroma,  Buruli ulcer,  Paraneoplastic pemphigus,  Chagas disease,  Heterotopic ossification.



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    Division of Dermatology, Department of Internal Medicine, Mercer University School of Medicine, Macon, GA 31207, USA. | Department of Dermatology, The Medical College of Georgia, Augusta, GA 30912, USA. | Department of Surgery, Mercer University Scho