KOL | Sarah T PendleburyDepartments of General (internal) Medicine and Geratology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK | John Radcliffe Hosp, Oxford | Wolfson Centre for ... |
KOL Resume for Sarah T Pendlebury
| Year | |
|---|---|
| 2022 | Departments of General (internal) Medicine and Geratology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK John Radcliffe Hosp, Oxford |
| 2021 | Departments of Internal Medicine and Geratology, John Radcliffe Hospital, Oxford, United Kingdom Wolfson Centre for Prevention of Stroke and Dementia, Wolfson Building, Nuffield Department of Clinical Neurosciences, University of Oxford, UK NIHR Oxford Biomedical Research Centre, John Radcliffe Hospital, OX3 9DU, Oxford, England |
| 2020 | Departments of Acute General Medicine and Geratology, John Radcliffe Hospital, Oxford, UK Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford, United Kingdom (S.T.P.). E-mail Address: [email protected] |
| 2019 | Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, NIHR Oxford Biomedical Research Centre, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom |
| 2018 | Departments of General (Internal) Medicine and Geratology, John Radcliffe hospital, Oxford, UK From the Nuffield Department of Clinical Neurosciences, Stroke Prevention Research Unit, University of Oxford, United Kingdom. |
| 2017 | John Radcliffe Hospital, and the University of Oxford Stroke Prevention Research Unit Oxford UK |
| 2016 | Stroke Prevention Research Unit, Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, UK Department of Neuroscience, University of Florence, Area Drug and Child Health (NEUROFARBA), Florence, Italy School of Psychiatry, University of New South Wales, Sydney, Australia Center for Health and Ageing (AGECAP), Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Sweden Sunnybrook Research Institute, University of Toronto, Canada |
| 2015 | From the Stroke Prevention Research Unit, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, United Kingdom (S.T.P., S.P.K., R.J.T., Z.M., R.M.W., P.M.R.); and Oxford NIHR Biomedical Research Centre, John Radcliffe Hospital, Oxford, United Kingdom (S.T.P.). Stroke Prevention Research Unit, Nuffield Department of Clinical Neurosciences, University of Oxford, UK |
| 2014 | From the Institute of Cardiovascular and Medical Sciences (R.L., P.L., D.J.S., T.J.Q.), Institute of Neuroscience and Psychology (J.S.), MRC/CSO Social and Public Health Sciences Unit (C.F.), University of Glasgow, UK; and NIHR Biomedical Research Centre and Stroke Prevention Research Unit, John Radcliffe Hospital, Oxford, UK (S.T.P.). |
| 2013 | NIHR Biomedical Research Centre, John Radcliffe Hospital, Oxford, UK From the Nuffield Department of Population Health, Health Economics Research Centre, University of Oxford, United Kingdom (R.L.-F., A.M.G.); and Stroke Prevention Research Unit, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, United Kingdom (N.L.M.P., S.T.P., L.M.B., S.J.V.W., F.C.C., P.M.R.). |
| 2012 | Stroke Prevention Research Unit, Nuffield Department of Clinical Neuroscience, and, NIHR Biomedical Research Centre, John Radcliffe Hospital, and, Oxford Project to Investigate Memory and Ageing (OPTIMA), Nuffield Department of Medicine, University of Oxford, Oxford, UK |
| 2011 | From the Stroke Prevention Research Unit (S.T.P., S.W., L.E.S., Z.M., P.M.R.), University Department of Clinical Neurology and the Biomedical Research Centre (S.T.P.), John Radcliffe Hospital, Oxford, UK. |
| 2010 | From the Stroke Prevention Research Unit (S.T.P., F.C.C., S.J.V.W., Z.M., P.M.R.), University Department of Clinical Neurology, John Radcliffe Hospital and the University of Oxford, Oxford, UK; and the National Institute of Health Research Biomedical Research Centre (S.T.P.), John Radcliffe Hospital, Oxford, UK. |
| 2009 | Stroke Prevention Research Unit, Level 6, West Wing, John Radcliffe Hospital, Oxford OX3 9DU, UK |
| 2007 | Stroke Prevention Research Unit, Department of Clinical Neurology, University of Oxford University, Oxford, UK. |
| 2004 | John S. Garvin Professor and Head, Department of Neurology and Rehabilitation, University of Illinois College of Medicine at Chicago, Chicago, Illinois From the Departments of Internal Medicine and Geratology (S.T.P.) and the Stroke Prevention Research Unit (P.M.R.), Department of Clinical Neurology, Radcliffe Infirmary, Oxford University, Oxford, UK; the Julius Centre for Health Sciences and Primary Care and the Department of Neurology (A.A., M.-J.A.), University Medical Centre of Utrecht, The Netherlands; the Department of Neurology 3 (G.B.), Bakirkoy Ruh ve Sinir Hastaliklari Hastanesi, Istanbul, Turkey; the Department of Neurology (A.C., K.K.), Institute of Psychiatry and Neurology, Warsaw, Poland; the Department of Neurology Donauklinikum and the Centre for Neurosciences (A.D., M.B.), Donau University, Maria Gugging, Austria; the Department of Neurology (Y.K.), Medical Faculty, Istanbul University, Turkey; the Department of Neurology and Neurosurgery (J.K.), University of Tartu, Estonia; the University Department of Neurology (S.K.), Grodno State Medical University, Grodno, Belarus; the Department of Neurology (P.M., J.B.), University Hospital, Lausanne, Switzerland; and the Department of Neurology (L.T.), Haukeland University Hospital, Bergen, Norway. Associate Professor, Department of Neurology, Director, Comprehensive Stroke Center, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania |
Sarah T Pendlebury: Influence Statistics
| Concept | World rank |
|---|---|
| escalated infection | #1 |
| pooled dementia rates | #1 |
| leukoaraiosis executive | #1 |
| n220 delirium | #1 |
| sdec factors | #1 |
| day emergency sdec | #1 |
| amts 9 | #1 |
| amts subjective | #1 |
| successful ambulatory | #1 |
| coding delirium | #1 |
| sepsis recognition tools | #1 |
| impairment moca | #1 |
| leukoaraiosis clinical scans | #1 |
| 4778 female | #1 |
| intervention administrative | #1 |
| studies compared subjects | #1 |
| structured paper proforma | #1 |
| strokespecific damage | #1 |
| newonset confusion | #1 |
| increased funding stroke | #1 |
| 700 192 years | #1 |
| worldwide underfunding | #1 |
| hospital administrative coding | #1 |
| delirium codes | #1 |
| 873±60 years | #1 |
| systematic review quarter | #1 |
| senior interface physician | #1 |
| escalated news | #1 |
| moca amts | #1 |
| dementia hospital stay | #1 |
| n1 pathology | #1 |
| clinical delirium diagnosis | #1 |
| amts moca | #1 |
| stroke executive | #1 |
| cognitive profiles mood | #1 |
| risk dementia status | #1 |
| sensitivity delirium coding | #1 |
| dementia tests stroke | #1 |
| 85 years factors | #1 |
| severe illness frailty | #1 |
| pooled dementia estimates | #1 |
| curve moca | #1 |
| study increased pathology | #1 |
| oxchronic | #1 |
Open the FULL List in Excel | |
Prominent publications by Sarah T Pendlebury
Differences in Cognitive Profile between TIA, Stroke and Elderly Memory Research Subjects: A Comparison of the MMSE and MoCA
[ PUBLICATION ]
BACKGROUND: The Montreal Cognitive Assessment (MoCA) appears more sensitive to mild cognitive impairment (MCI) than the Mini-Mental State Examination (MMSE): over 50% of TIA and stroke patients with an MMSE score of ≥27 ('normal' cognitive function) at ≥6 months after index event, score <26 on the MoCA, a cutoff which has good sensitivity and specificity for MCI in this population. We hypothesized that sensitivity of the MoCA to MCI might in part be due to detection of different patterns ...
| Known for Mmse Moca | Tia Stroke | Cognitive Profile | Impairment Mci | Patients Age |
BACKGROUND AND PURPOSE: The Montreal Cognitive Assessment (MoCA) and Addenbrooke's Cognitive Examination-Revised (ACE-R) are proposed as short cognitive tests for use after stroke, but there are few published validations against a neuropsychological battery. We studied the relationship between MoCA, ACE-R, Mini-Mental State Examination (MMSE) and mild cognitive impairment (MCI) in patients with cerebrovascular disease and mild cognitive impairment (MCI).
METHODS: One hundred consecutive ...
| Known for Neurological Disorders | Cognitive Impairment | Neuropsychological Battery | National Institute | Mmse Moca |
BACKGROUND: Risk of dementia after stroke is a major concern for patients and carers. Reliable data for risk of dementia, particularly after transient ischaemic attack or minor stroke, are scarce. We studied the risks of, and risk factors for, dementia before and after transient ischaemic attack and stroke.
METHODS: The Oxford Vascular Study is a prospective incidence study of all vascular events in a population of 92 728 people residing in Oxfordshire, UK. Patients with transient ...
| Known for Dementia Stroke | Oxford Vascular Study | Transient Ischaemic Attack | Nihss Score | Low Education |
Prevalence, incidence, and factors associated with pre-stroke and post-stroke dementia: a systematic review and meta-analysis
[ PUBLICATION ]
BACKGROUND: Reliable data on the prevalence and predictors of post-stroke dementia are needed to inform patients and carers, plan services and clinical trials, ascertain the overall burden of stroke, and understand its causes. However, published data on the prevalence and risk factors for pre-stroke and post-stroke dementia are conflicting. We undertook this systematic review to assess the heterogeneity in the reported rates and to identify risk factors for pre-stroke and post-stroke ...
| Known for Dementia Stroke | 10 Patients | Case Mix | Hospitalbased Studies | Reliable Data |
BACKGROUND: Mild cognitive impairment (MCI) is at least as prevalent as dementia after transient ischaemic attack (TIA)/stroke and is increasingly recognised as an important outcome in observational studies and randomised trials. However, there is no consensus on how impairment should be defined, and numerous different criteria exist. Previous studies have shown that different criteria for cognitive impairment impact on prevalence rates in epidemiological studies. However, there are few ...
| Known for Cognitive Impairment | Mmse Moca | Tia Stroke | Neuropsychological Tests | Attack Transient |
BACKGROUND AND PURPOSE: Among screening tools for cognitive impairment in large cohorts, the Montreal Cognitive Assessment (MoCA) seems to be more sensitive to early cognitive impairment than the Mini-Mental State Examination (MMSE), particularly after transient ischemic attack or minor stroke. We reasoned that if MoCA-detected early cognitive impairment is pathologically significant, then it should be specifically associated with the presence of white matter hyperintensities (WMHs) and ...
| Known for Minor Stroke | Transient Ischemic Attack | Early Cognitive Impairment | White Matter | Cognitive Assessment |
BACKGROUND AND PURPOSE: The Mini-Mental State Examination (MMSE) is insensitive to mild cognitive impairment and executive function. The more recently developed Montreal Cognitive Assessment (MoCA), an alternative, brief 30-point global cognitive screen, might pick up more cognitive abnormalities in patients with cerebrovascular disease.
METHODS: In a population-based study (Oxford Vascular Study) of transient ischemic attack and stroke, the MMSE and MoCA were administered to consecutive ...
| Known for Mmse Moca | Cognitive Impairment | Transient Ischemic | Executive Function | Mental State |
BACKGROUND AND PURPOSE: Face-to-face cognitive testing is not always possible in large studies. Therefore, we assessed the telephone Montreal Cognitive Assessment (T-MoCA: MoCA items not requiring pencil and paper or visual stimulus) and the modified Telephone Interview of Cognitive Status (TICSm) against face-to-face cognitive tests in patients with transient ischemic attack (TIA) or stroke.
METHODS: In a population-based study, consecutive community-dwelling patients underwent the MoCA ...
| Known for Transient Ischemic Attack | Telephone Assessment | Tia Stroke | Tmoca Mci | Cognitive Status |
Test Accuracy of Cognitive Screening Tests for Diagnosis of Dementia and Multidomain Cognitive Impairment in Stroke
[ PUBLICATION ]
BACKGROUND AND PURPOSE: Guidelines recommend screening stroke-survivors for cognitive impairments. We sought to collate published data on test accuracy of cognitive screening tools.
METHODS: Index test was any direct, cognitive screening assessment compared against reference standard diagnosis of (undifferentiated) multidomain cognitive impairment/dementia. We used a sensitive search statement to search multiple, cross-disciplinary databases from inception to January 2014. Titles, ...
| Known for Test Accuracy | Sensitivity Specificity | Cognitive Screening | Independent Researchers | Impairment Stroke |
BACKGROUND AND PURPOSE: Acute cognitive impairment and delirium occur after major stroke and are associated with poor cognitive outcome. We conducted a population-based study to determine whether transient cognitive impairment (TCI) is seen acutely after cerebral transient ischemic attack (TIA) or minor stroke, and whether it predicts long-term cognitive decline.
METHODS: Mini-mental-state examination was performed in consecutive testable patients with TIA or minor stroke (National ...
| Known for Minor Stroke | Transient Cognitive Impairment | Patients Tia | Computed Tomography | Follow Studies |
OBJECTIVES: We aimed to determine age-specific rates of delirium and associated factors in acute medicine, and the impact of delirium on mortality and re-admission on long-term follow-up.
DESIGN: Observational study. Consecutive patients over two 8-week periods (2010, 2012) were screened for delirium on admission, using the confusion assessment method (CAM), and reviewed daily thereafter. Delirium diagnosis was made using the Diagnostic and Statistical Manual Fourth Edition (DSM IV) ...
| Known for Delirium Admission | Patients Age | Acute Medicine | Factors Mortality | ≥65 Years |
Risk of Recurrent Stroke, Other Vascular Events and Dementia after Transient Ischaemic Attack and Stroke
[ PUBLICATION ]
The early risk of recurrence after transient ischaemic attack (TIA) or minor stroke is high, ranging from 11% at 7 days in population-based studies, where patients are seen non-urgently, to 3% at 7 days in studies where patients are seen urgently in specialist services. In long-term (up to 10 years) studies of vascular risks after TIA and stroke, the risk of stroke is highest early after the event, and then falls, whereas the risk of coronary events is constant over the follow-up period ...
| Known for Stroke Risk | Vascular Events | Ischemic Attack | Factors Secondary | Populationbased Studies |
Functional MRI Detects Posterior Shifts in Primary Sensorimotor Cortex Activation After Stroke
[ PUBLICATION ]
BACKGROUND AND PURPOSE: Further recovery from stroke can occur late, long after the end of the apparent evolution of pathological changes. This observation and evidence obtained from functional imaging for altered patterns of activation after brain injury suggest that cortical reorganization may contribute to recovery. Here, we have tested for potentially adaptive reorganization in the primary sensorimotor cortex.
METHODS: We used functional MRI to study brain activation with dominant ...
| Known for Functional Mri | Sensorimotor Cortex | Recovery Stroke | Patients Control Subjects | Female Fingers |
The motor cortex shows adaptive functional changes to brain injury from multiple sclerosis
[ PUBLICATION ]
Although multiple sclerosis (MS) is an inflammatory demyelinating disease, there can be substantial axonal injury and loss. We therefore hypothesized that adaptive cortical changes may contribute to limiting functional impairment, particularly in the early stages of the disease. To test our hypothesis, we used functional magnetic resonance imaging (MRI) to characterize the localization and volumes of activation in the motor cortex during simple flexion-extension finger movements. There ...
| Known for Motor Cortex | Adaptive Functional | Multiple Sclerosis | Brain Injury | Cortical Activation |
Population-Based Study of Disability and Institutionalization After Transient Ischemic Attack and Stroke
[ PUBLICATION ]
BACKGROUND AND PURPOSE: Long-term outcome information after transient ischemic attack (TIA) and stroke is required to help plan and allocate care services. We evaluated the impact of TIA and stroke on disability and institutionalization over 5 years using data from a population-based study.
METHODS: Patients from a UK population-based cohort study (Oxford Vascular Study) were recruited from 2002 to 2007 and followed up to 2012. Patients were followed up at 1, 6, 12, 24, and 60 months ...
| Known for Patients Stroke | 5 Years | Ischemic Attack | Modified Rankin Scale | Populationbased Study |
Key People For Cognitive Impairment
Sarah T Pendlebury:Expert Impact
Concepts for whichSarah T Pendleburyhas direct influence:Cognitive impairment, Minor stroke, Transient ischemic attack, Internal capsule, Tia stroke, Test accuracy, Motor deficit, Transient ischaemic attack.
Sarah T Pendlebury:KOL impact
Concepts related to the work of other authors for whichfor which Sarah T Pendlebury has influence:Cognitive impairment, Multiple sclerosis, Ischemic stroke, Vascular dementia, Magnetic resonance, Blood pressure, White matter.
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