Tilman T Zittel: Influence Statistics

Tilman T Zittel

Tilman T Zittel

Hudiksvall Hospital, Department of Surgery, Colorectal Section, Hudiksvall, Sweden | University Hospital for General, Visceral and Transplant Surgery, Tuebingen, Germany | ...

Tilman T Zittel: Expert Impact

Concepts for which Tilman T Zittel has direct influence: Food intake , Awake rats , Total gastrectomy , Colonic motility , Gastric motility , Colorectal surgery , Postoperative colonic .

Tilman T Zittel: KOL impact

Concepts related to the work of other authors for which for which Tilman T Zittel has influence: Food intake , Postoperative ileus , Gastrointestinal tract , Rectal prolapse , Gastric emptying , Total gastrectomy , Abdominal surgery .

KOL Resume for Tilman T Zittel


Hudiksvall Hospital, Department of Surgery, Colorectal Section, Hudiksvall, Sweden


University Hospital for General, Visceral and Transplant Surgery, Tuebingen, Germany


Department of General Surgery, Eberhard-Karls-University Tuebingen, Hoppe-Seyler-Straβe 3, 72076, Tuebingen, Germany


Department of General, Visceral and Transplantation Surgery, University Hospital, Hoppe‐Seyler‐Strasse 3, 72076 Tübingen, Germany


From the Department of General Surgery, University Hospital Tuebingen, Tuebingen Germany


Department of General, Visceral and Transplantation Surgery, University Hospital, Hoppe-Seyler-Strasse 3, 72076, Tübingen, Germany

Klinik f?r Allgemeine Chirurgie, Viszeral- und Transplantationschirurgie, Universit?t T?bingen(? rztlicher Direktor: Prof. Dr. Dr. h. c. H. D. Becker)


Department of General Surgery, University Hospital, University of Tübingen, Germany


Tübingen, Germany


University Hospital, Department of General and Transplantation Surgery, Tübingen University, Hoppe-Seyler-Str. 3, D-72076 Tübingen, Germany e-mail: Tel.: +49-7071-2986611 Fax: +49-7071-295500, DE

Department of General Surgery


Chirurgische Abteilung, Universitätsklinik Tübingen, Waldhörnlestraße 22, 72072, Tübingen, Germany


From Cure/GASTROENTERIC Biology Center, West Los Angeles Va Medical Center, And University Of California, Los Angeles, Calif., And Department Of Abdominal And Transplantation Surgery, TüBINGEN, Germany


From University Hospital, Department of Abdominal and Transplantation Surgery, Tübingen, Germany

Abteilung für Allgemeinchirurgie (Direktor: Prof. Dr. H. D. Becker), Chirurgische Universitätsklinik Tübingen, XX


Department of Abdominal and Transplantation Surgery, University Hospital, Tübingen, Germany


CURE: VA / UCLA Gastroenteric Biology Center VAMC-Wadsworth, Los Angeles, CA 90073, USA

From the University Hospital, Department of Abdominal and Transplantation Surgery, Tübingen, Germany (TTZ, BvE, RKT, HDB)


Center for Ulcer Research and Education, Veterans Affairs/Universityof California, Los Angeles.

University Hospital Department of Abdominal and Transplantation Surgery Tübingen, Germany


Department of Anatomy, School of Medicine, Los Angeles, CA USA

Prominent publications by Tilman T Zittel

KOL-Index: 12462 . CCK-A receptors and neurons of the nucleus of the solitary tract (NTS) are involved in the regulation of food intake, and in rats, there is evidence for involvement of an intestinal vagal afferent pathway. Studies investigating the role of CCK-A receptors in activation of NTS neurons using highly selective CCK-A receptor agonists and antagonists have yielded conflicting data. In the ...
Known for Solitary Tract | Nts Neurons | Food Intake | Cholecystokinin Receptor
KOL-Index: 11894 . Gastrointestinal motility is strongly inhibited during peritonitis or sepsis and proinflammatory cytokines released into mesenteric lymph during an acute gastrointestinal insult mediate systemic responses. We investigated whether mesenteric lymph collected during peritonitis or sepsis inhibits gastric motility and gastric emptying. Mesenteric lymph was collected for 12 hours from three ...
Known for Mesenteric Lymph | Gastric Motility | Recipient Rats | Emptying Gastrointestinal
KOL-Index: 10817 . BACKGROUND: Gastrointestinal motility is frequently impaired after abdominal surgery. We investigated the effects of neostigmine on colonic motility in patients after colorectal surgery and in healthy volunteers. METHODS: Colonic motility was recorded by a manometry/barostat system in 12 patients after left colonic or rectal resection during baseline and after the intravenous ...
Known for Colonic Motility | Colorectal Surgery | Neostigmine Postoperative | Mm Hg
KOL-Index: 10773 . The purpose of the study was to determine the overall risk of a permanent stoma in patients with complicated perianal Crohn's disease, and to identify risk factors predicting stoma carriage. A total of 102 consecutive patients presented with the first manifestation of complicated perianal Crohn's disease in our outpatient department between 1992 and 1995. Ninety-seven patients (95%) could ...
Known for Fecal Diversion | Perianal Crohn | Permanent Stoma | Rectal Resection
KOL-Index: 10503 . C-fos protein expression was investigated in the nucleus of the solitary tract (NTS) in response to increasing cholecystokinin (CCK) doses and food intake in rats by counting the number of c-fos protein positive cells in the NTS. C-fos protein expression in the NTS dose-dependently increased in response to CCK, the lowest effective dose being 0.1 microg/kg. The ED(50) for c-fos protein ...
Known for Food Intake | Solitary Tract | Fos Protein | Cholecystokinin Dose
KOL-Index: 10444 . PURPOSE: Colonic motility is crucial for the resolution of postoperative ileus. However, few data are available on postoperative colonic motility and no data on postoperative colonic tone. We aimed to characterize postoperative colonic tone and motility in patients. METHODS: Nineteen patients were investigated with combined barostat and manometry recordings after left colonic surgery. ...
Known for Colonic Motility | Colorectal Surgery | Postoperative Ileus | Barostat Bag
KOL-Index: 10198 . BACKGROUND: Postoperative ileus influences patients well-being, hospital stay, and health cost, and postoperative inhibition of colonic motility is a major contributor to postoperative ileus. Experimental models for investigating postoperative ileus are needed. In particular, recording of postoperative colonic motility in awake rats has not been described yet. MATERIAL AND METHODS: ...
Known for Awake Rats | Postoperative Ileus | Gastrointestinal Motility | Strain Gauge Transducers
KOL-Index: 10049 . BACKGROUND & AIMS: Functional effects mediated via the 5-hydroxytryptamine3 receptor (5-HT3R) can be elicited from both extrinsic and intrinsic neurons innervating the gastrointestinal (GI) tract. Clinically, 5-HT3 antagonists are important in the treatment of emesis and have been used for the treatment of symptoms in functional bowel disease. The aim of the present study was to elucidate ...
Known for Gastrointestinal Tract | Serotonin Receptors | Interstitial Cells | 5 Ht3r
KOL-Index: 9656 . Nutrients in the intestine inhibit food intake via an action on the vagal afferent pathway. The aim of the present study was to use immunochemical detection of Fos protein-like immunoreactivity (FLI) in the brainstem to trace the neuronal pathways activated by intestinal nutrients. Perfusion of the intestine of awake rats via an indwelling duodenal catheter with iso-osmotic mannitol, ...
Known for Solitary Tract | Intestinal Nutrients | Fos Protein | Awake Rats
KOL-Index: 9616 . OBJECTIVE: The object of this study was to investigate the mechanisms of postoperative gastric ileus in an experimental model of abdominal surgery in anesthetized rats. SUMMARY BACKGROUND DATA: Sensory neurons partly mediate postoperative gastric ileus. Among other neuropeptides, sensory neurons contain calcitonin gene-related peptide (CGRP) and release CGRP in response to noxious ...
Known for Postoperative Gastric Ileus | Abdominal Surgery | Calcitonin Gene | Gastric Motility
KOL-Index: 9529 . BACKGROUND: Total gastrectomy often results in early satiety and loss of body weight. Serotonin inhibits food intake, and postprandial serotonin release is increased after total gastrectomy. Serotonin might contribute to early satiety and loss of body weight after total gastrectomy. METHODS AND MATERIALS: Food intake and body weight were investigated with an automated recording system in ...
Known for Food Intake | Total Gastrectomy | Serotonin Receptor | Early Satiety
KOL-Index: 9303 . BACKGROUND: Studies indicate that gastrectomy might alter calcium and bone metabolism, resulting in bone disorders. No data are currently available on the prevalence of bone disorders after gastrectomy. METHODS: Sixty gastrectomy patients were investigated for serum parameters of calcium and bone metabolism 5 to 20 years postoperatively and compared to an age- and sex-matched healthy ...
Known for Bone Disorders | Calcium Metabolism | Gastrectomy Patients | Vertebral Fractures
KOL-Index: 9210 . Nutrients in the intestine initiate changes in secretory and motor function of the gastrointestinal (GI) tract. The nature of the 'sensors' in the intestinal wall is not well characterized. Intestinal lipid stimulates the release of cholecystokinin (CCK) from mucosal entero-endocrine cells, and it is proposed that CCK activates CCK A receptors on vagal afferent nerve terminals. There is ...
Known for Vagal Afferent | Gastric Motility | Motor Function | Cholecystokinin Receptors
KOL-Index: 9064 . BACKGROUND: Calcitonin gene-related peptide (CGRP) is a widely distributed neuropeptide contained in intrinsic and extrinsic neurons of the gastrointestinal wall that has been shown to be released by noxious stimulation, to be involved in nociception, to inhibit gastrointestinal motility, and to partly mediate postoperative gastric ileus. We hypothesized that abdominal surgery-induced ...
Known for Postoperative Colonic | Food Intake | Calcitonin Gene | Abdominal Surgery
KOL-Index: 8506 . INTRODUCTION: The indication for surgery after conservative treatment of acute diverticulitis is still under debate. This is partly as a result of limited data on the outcome of conservative management in the long run. We therefore aimed to determine the long-term results of conservative treatment for acute diverticulitis. METHODS: The records of all patients treated at our institution for ...
Known for Conservative Treatment | Patients Diverticulitis | Sigmoid Colon | Term Outcome

Key People For Food Intake

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Hudiksvall Hospital, Department of Surgery, Colorectal Section, Hudiksvall, Sweden | University Hospital for General, Visceral and Transplant Surgery, Tuebingen, Germany | Department of General, Visceral and Transplantation Surgery, University Hospit