Evelien Dekker: Influence Statistics

Evelien Dekker

Evelien Dekker

Amsterdam University Medical Centers location University of Amsterdam, Department of Gastroenterology and Hepatology, Amsterdam, the Netherlands; Amsterdam Gastroenterology ...

Evelien Dekker: Expert Impact

Concepts for which Evelien Dekker has direct influence: Colorectal cancer , Optical diagnosis , Advanced neoplasia , Gastrointestinal endoscopy , Lynch syndrome , Familial adenomatous polyposis , Glucose production .

Evelien Dekker: KOL impact

Concepts related to the work of other authors for which for which Evelien Dekker has influence: Colorectal cancer , Lynch syndrome , Early detection , Bowel preparation , Serrated polyps , Ulcerative colitis , Venous thromboembolism .

KOL Resume for Evelien Dekker


Amsterdam University Medical Centers location University of Amsterdam, Department of Gastroenterology and Hepatology, Amsterdam, the Netherlands; Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, the Netherlands; Cancer Center Amsterdam, Amsterdam, the Netherlands.


Department of Gastroenterology and Hepatology, Cancer Center Amsterdam, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands


Department of Gastroenterology and Hepatology, Academic Medical Centre, Amsterdam, The Netherlands


Gastroenterology and Hepatology, Academic Medical Center, Amsterdam, the Netherlands.

Amsterdam UMC (Netherlands)


Department of Gastroenterology and Hepatology, Academic Medical Center University of Amsterdam, Amsterdam, the Netherlands

See end of article for the full list of members of the DISCOUNT study group

Prominent publications by Evelien Dekker

KOL-Index: 21676 . OBJECTIVE: Fecal immunochemical testing (FIT) is increasingly used for colorectal cancer (CRC) screening. We aimed to estimate its diagnostic accuracy in invitational population screening measured against colonoscopy. METHODS: Participants (50-75 years) in an invitational primary colonoscopy screening program were asked to complete one sample FIT before colonoscopy. We estimated FIT ...
Known for Advanced Neoplasia | Sensitivity Specificity | 95 Crc | Occult Blood
KOL-Index: 19633 . BACKGROUND: Endoscopic tri-modal imaging (ETMI) incorporates white light endoscopy (WLE), autofluorescence imaging (AFI) and narrow-band imaging (NBI). AIMS: To assess the value of ETMI for the detection and classification of neoplasia in patients with longstanding ulcerative colitis. DESIGN: Randomised comparative trial of tandem colonoscopies. SETTING: Academic Medical Centre Amsterdam, ...
Known for Ulcerative Colitis | Neoplasia Detection | Afi Wle | Autofluorescence Imaging
KOL-Index: 18431 . BACKGROUND: Screening for colorectal cancer is widely recommended, but the preferred strategy remains unidentified. We aimed to compare participation and diagnostic yield between screening with colonoscopy and with non-cathartic CT colonography. METHODS: Members of the general population, aged 50-75 years, and living in the regions of Amsterdam or Rotterdam, identified via the registries ...
Known for Colorectal Cancer | Colonoscopy Colonography | Advanced Neoplasia | Diagnostic Yield
KOL-Index: 17415 . BACKGROUND: Lynch syndrome is a disorder caused by mismatch repair gene mutations. Mutation carriers have a high risk of developing colorectal cancer. In patients with Lynch syndrome in whom colon cancer has been diagnosed, in general, subtotal colectomy instead of partial colectomy is recommended because of the substantial risk of metachronous colorectal cancer. However, the effect of ...
Known for Lynch Syndrome | Colon Cancer | Quality Life | Subtotal Colectomy
KOL-Index: 17235 . BACKGROUND AND STUDY AIM: Patients with longstanding ulcerative colitis are at increased risk of developing colorectal cancer. Colonoscopic surveillance is advised, but the detection of neoplasia by conventional colonoscopy is difficult. The aim of this study was to compare the accuracy of narrow-band imaging (NBI), a new imaging technique, with standard colonoscopy for the detection of ...
Known for Conventional Colonoscopy | Longstanding Ulcerative Colitis | Neoplasia Patients | Targeted Biopsies
KOL-Index: 15927 . MAIN RECOMMENDATIONS: The following recommendations for post-polypectomy endoscopic surveillance should be applied only after a high quality baseline colonoscopy with complete removal of all detected neoplastic lesions.1 In the low risk group (patients with 1 - 2 tubular adenomas < 10 mm with low grade dysplasia), the ESGE recommends participation in existing national screening programmes ...
Known for Colonoscopy Surveillance | Strong Recommendation | Gastrointestinal Endoscopy | European Society
KOL-Index: 15923 . BACKGROUND & AIMS: Among subjects screened for colorectal cancer (CRC) by the guaiac fecal occult blood test, interval cancers develop in 48% to 55% of the subjects. Data are limited on how many persons screened by fecal immunochemical tests (FIT), over multiple rounds, develop interval cancers. In the Netherlands, a pilot FIT-based biennial CRC screening program was conducted between 2006 ...
Known for Multiple Rounds | Colorectal Cancer | Crc Fit | Fecal Immunochemical
KOL-Index: 15129 . This manuscript represents an official Position Statement of the European Society of Gastrointestinal Endoscopy (ESGE) aiming to guide general gastroenterologists to develop and maintain skills in optical diagnosis during endoscopy. In general, this requires additional training beyond the core curriculum currently provided in each country. In this context, ESGE have developed a European ...
Known for Optical Diagnosis | Gastrointestinal Endoscopy | European Society | Position Statement
KOL-Index: 15070 . BACKGROUND: Constitutive Wnt activation is essential for colorectal cancer (CRC) initiation but also underlies the cancer stem cell phenotype, metastasis and chemosensitivity. Importantly Wnt activity is still modulated as evidenced by higher Wnt activity at the invasive front of clonal tumours termed the β-catenin paradox. SMAD4 and p53 mutation status and the bone morphogenetic protein ...
Known for Wnt Pathway | Bmp Signalling | Crc Smad4 | Protein P53
KOL-Index: 14927 . BACKGROUND & AIMS: Endoscopic trimodal imaging (ETMI) incorporates high-resolution endoscopy (HRE) and autofluorescence imaging (AFI) for adenoma detection, and narrow-band imaging (NBI) for differentiation of adenomas from nonneoplastic polyps. The aim of this study was to compare AFI with HRE for adenoma detection and to assess the diagnostic accuracy of NBI for differentiation of ...
Known for Colonic Polyps | Hre Afi | Endoscopic Trimodal Imaging | Adenoma Detection
KOL-Index: 14609 . BACKGROUND & AIMS: Despite poor performance, guaiac-based fecal occult blood tests (G-FOBT) are most frequently implemented for colorectal cancer screening. Immunochemical fecal occult blood tests (I-FOBT) are claimed to perform better, without randomized comparison in screening populations. Our aim was to randomly compare G-FOBT with I-FOBT in a screening population. METHODS: We conducted ...
Known for Screening Population | Random Comparison | Advanced Adenomas | Blood Tests
KOL-Index: 14482 . BACKGROUND & AIMS: Two percent to 4% of all cases of colorectal cancer (CRC) are associated with Lynch syndrome. Dominant clustering of CRC (non-Lynch syndrome) accounts for 1%-3% of the cases. Because carcinogenesis is accelerated in Lynch syndrome, an intensive colonoscopic surveillance program has been recommended since 1995. The aim of the study was to evaluate the effectiveness of ...
Known for Lynch Syndrome | Surveillance Intervals | Colorectal Cancer | Risk Crc
KOL-Index: 14425 . BACKGROUND: The effectiveness of colorectal cancer screening programs based on the fecal immunochemical test (FIT) is influenced by program adherence during consecutive screening rounds. We aimed to evaluate the participation rate, yield, and interval cancers in a third round of biennial CRC screening using FIT and to compare those with the first and the second screening round. METHODS: A ...
Known for Cancer Screening | Based Colorectal | Advanced Neoplasia | Participants Round
KOL-Index: 14260 . BACKGROUND & AIMS: Consecutive rounds of fecal occult blood tests (FOBTs) are used to screen for colorectal cancer (CRC); they detect precursor lesions and early-stage disease. We assessed whether the positivity rate and the positive predictive values (PPVs) for advanced neoplasia and CRC decrease with repeated testing by using fecal immunochemical tests (FITs). METHODS: Data were ...
Known for Advanced Neoplasia | Colorectal Cancer | Fit Round | Lower Risk

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Amsterdam University Medical Centers location University of Amsterdam, Department of Gastroenterology and Hepatology, Amsterdam, the Netherlands; Amsterdam Gastroenterology Endocrinology Metabolism, Amsterdam, the Netherlands; Cancer Center Amsterdam