Ib Jarle Christensen

Ib Jarle Christensen

Finsen Laboratory, Copenhagen University Hospital, Strandboulevarden 49, Dk-2100 Copenhagen, Denmark. Lund@inet.uni2.dk

Direct Impact

Concepts for which Ib Jarle Christensen has direct influence:

colorectal cancer
serum ykl-40
plasma timp-1
tissue inhibitor
flow cytometry
prognostic factor
objective response

External impact

Concepts related to the work of other authors for which Ib Jarle Christensen has influence:

colorectal cancer
tissue inhibitor
neoadjuvant chemotherapy
serum ykl-40
urokinase-type plasminogen activator
advanced adenoma
diagnostic colonoscopy

Prominent publications by Ib Jarle Christensen

KOL-Index: 65 INTRODUCTION: Blood-based, cancer-associated biomarkers are susceptible to a variety of well-known preanalytical factors. The influence of bowel preparation before a diagnostic colonoscopy on biomarker levels is, however, poorly investigated. The present study assessed the influence of bowel preparation on colorectal cancer-associated biomarkers. In addition, the effect of single versus ...
Known for
125 | Serum Edta Plasma | Galectin-3 | 4 Cell-Free Dna
KOL-Index: 53 Implementation of population screening for colorectal cancer by direct colonoscopy or follow-up colonoscopy after a positive fecal blood test has challenged the overall capacity of bowel examinations. Certain countries are facing serious colonoscopy capacity constraints, which have led to waiting lists and long time latency of follow-up examinations. Various options for improvement are ...
Known for
Follow-Up Colonoscopy | Cancer-Associated Biomarkers | Increased Cut-Off Values | Blood Cancer
KOL-Index: 48 BACKGROUND: In developed countries, women attend follow-up after treatment for cervical cancer to detect recurrence. The aim of this study was to describe the Danish population of women with early-stage cervical cancer at risk for recurrence and death due to recurrence. METHODS: Data were extracted from 3 nationwide databases to find women diagnosed with stage 1A1 to 1B1 cervical cancer in ...
Known for
Inferior Survival | Stage 1a1 | 1523 | Oncological Surgical
KOL-Index: 48 The purpose of this study was to investigate the association between tumor tissue levels of total tissue inhibitor of metalloproteinases-1 (TIMP-1) and prognosis in patients with primary breast cancer and to analyze whether measurement of TIMP-1 in tumor extracts added prognostic information to that obtained from measurements of urokinase-type plasminogen activator and plasminogen activator ...
Known for
Survival Tumor | Inhibitor Pai-1 | Cancer Timp-1 | Tissue Primary
KOL-Index: 48 INTRODUCTION: Effective predictive biomarkers for selection of patients benefiting from adjuvant platinum-based chemotherapy in non-small cell lung cancer (NSCLC) are needed. Based on a previously validated methodology, molecular profiles of predicted sensitivity in two patient cohorts are presented. METHODS: The profiles are correlations between in vitro sensitivity to cisplatin and ...
Known for
Multivariate Model | Completely Resected Stage 1a-3b | 1 Snap-Frozen Tumors | Vinorelbine Acv
KOL-Index: 39 Mannan-binding lectin (MBL) and MBL-associated serine protease 2 (MASP-2) are key factors of the lectin pathway of complement activation. Polymorphisms of the MBL2 and MASP-2 genes affect serum levels of MBL and MASP-2. In patients with colorectal cancer (CRC), the MBL and MASP-2 serum levels are increased and high MASP-2 levels are associated with recurrence and poor survival, whereas low ...
Known for
Recurrent Cancer | Mbl‐associated Serine | Snp D120 | Binding Lectin
KOL-Index: 38 Introduction: Most of the subjects undergoing diagnostic colonoscopy do not have neoplastic bowel lesions. Potentially, some of the symptoms may therefore be caused by extracolonic malignancy, and subjects with persisting symptoms may need subsequent examinations. Blood-based, cancer-associated biomarkers may aid in directing the examinations for other specific malignant diseases. Methods: ...
Known for
Model Extracolonic | Ovary Cancer | Examinations Colonoscopy | Persisting Symptoms
KOL-Index: 37 The effect of sodium butyrate on cell proliferation was studied in eight human urothelial cell lines differing in transformation grade (TGr): Hu 1752 (mortal, TGr I); HCV29 (immortal and tumorigenic, TGr II); HCV29T, T24, T24A, T24B, Hu 961A and Hu 1703He (tumorigenic, TGr III). In all cell lines, except Hu 1752, addition of 4 mM sodium butyrate at 18 h after replating resulted in a ...
Known for
Lines Dna | Hcv29 961a | 1703he | Pronounced Accumulation
KOL-Index: 37 BACKGROUND: Only a few small studies have evaluated risk factors related to early death following emergency surgery for colonic cancer. The aim of this study was to identify risk factors for death within 30 days after such surgery. METHODS: Some 2157 patients who underwent emergency treatment for colonic cancer from May 2001 to December 2005 were identified from the national colorectal ...
Known for
30-Day Rate | Postoperative Surgical Complications | Colorectal Cancer Registry | Early Identified
KOL-Index: 36 OBJECTIVES: For patients with melanoma, ulceration is an important prognostic marker and interestingly also a predictive marker for the response of adjuvant interferon. A consensual definition and accurate assessment of ulceration are therefore crucial for proper staging and clinical management. We evaluated the prognostic impact of the extent and type of ulceration and the epidermal ...
Known for
He-Stained Sections | Epidermis Cleft Formation | Stratification Ulcerated | 385

Finsen Laboratory, Copenhagen University Hospital, Strandboulevarden 49, DK-2100 Copenhagen, Denmark. lund@inet.uni2.dk

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