Harry P. W. Kozakewich

Harry P. W. Kozakewich

From The Departments Of *pathology, †radiology, †surgery, And §gynecology, Children's Hospital And Harvard Medical School, Boston, Ma.

Direct Impact

Concepts for which Harry P W Kozakewich has direct influence:

congenital hemangioma
pyogenic granuloma
vascular malformations
young adults
kaposiform hemangioendothelioma
bronchial atresia
soft tissue

External impact

Concepts related to the work of other authors for which Harry P W Kozakewich has influence:

vascular malformations
hereditary hemorrhagic telangiectasia
hepatic vein
epidermoid cyst
acute liver
doppler ultrasonography
biliary ischemia

Prominent publications by Harry P. W. Kozakewich

KOL-Index: 231 Over the past decade, many changes and updates have occurred in the world of vascular anomalies, including their histopathology. An appreciation has developed that a combined team approach is optimal in arriving at a correct diagnosis. Technical advances such as immunohistochemical stains for GLUT1, an excellent marker for infantile hemangioma, and vascular immunostains such as D2-40, PROX1, ...
Known for
Anomalies Histopathology
KOL-Index: 52 Vascular anomalies in children and adolescents are the most common soft tissue lesions and include reactive, malformative, and neoplastic tumefactions, with a full spectrum of benign, intermediate, and malignant neoplasms. These lesions are diagnostically challenging because of morphologic complexity and recent changes in classification systems, some of which are based on clinical features ...
Known for
Adolescents Soft | Diagnosis Pathologic | Features Vascular | Anomalies Children
KOL-Index: 43 BackgroundTesticular epidermoid cyst is a rare benign tumor in children. Although this entity is widely described in adults in literature, there are no large series describing the pathological and radiological findings in children. Knowledge of the sonographic features seen in children may alter surgical treatment.ObjectiveTo describe the specific US characteristics of testicular epidermoid ...
Known for
Single Children’s | Backgroundtesticular Epidermoid Cyst | Youngest | Rare Benign Tumor
KOL-Index: 39 Nonketotic hyperglycinaemia (NKH) is an autosomal recessive disorder characterized by defective glycine degradation by the mitochondrial glycine cleavage system. The clinical features include lethargy, hypotonia, apnoea, seizures and severe psychomotor retardation, all attributed to the accumulation of glycine in the nervous system. Pulmonary hypertension (PHN) has not been reported in NKH. ...
Known for
Hyperglycinaemia | Hypertension Phn | Nonketotic
KOL-Index: 33 With the increasing practice of gender-affirming mastectomy as a therapeutic procedure in the setting of gender dysphoria, there has come a profusion of literature on the pathologic findings within these specimens. Findings reported in over 1500 patients have not included either prostatic metaplasia or pilar metaplasia of breast epithelium. We encountered both of these findings in the course ...
Known for
1500 | Forty-Three Mammoplasty | Basal Layer | 20 Additional Archival Gender-Affirming
KOL-Index: 32 Mesenteric lipoblastoma is a rare tumor and, its presentation as a bowel obstruction with possible midgut volvulus has only been reported once before. A 7-year-old girl presented with nausea and vomiting but a benign abdominal examination. Upper gastrointestinal contrast study demonstrated possible malrotation with midgut volvulus. During emergency laparotomy, segmental small bowel volvulus ...
Known for
7-Year-Old Girl | Benign Abdominal Examination | Segmental Small Bowel Volvulus | Upper Gastrointestinal Contrast
KOL-Index: 30 Pyogenic granuloma, also called lobular capillary hemangioma, is a condition usually occurring in skin or mucosa and often related to prior local trauma or pregnancy. However, the etiopathogenesis of pyogenic granuloma is poorly understood and whether pyogenic granuloma being a reactive process or a tumor is unknown. In an attempt to clarify this issue, we performed genome-wide ...
Known for
Process Linked | Granuloma Reactive | Angiogenesis Vascular | Injury Impaired
KOL-Index: 29 Cystic neuroblastoma (CN) is an unusual variant of neuroblastoma characterized by a grossly visible cyst(s) and almost always distinctive microcysts on light microscopy. Rarely, CN will appear solid grossly, but microcystification will be present. We examined the clinical, pathologic, and biologic features of 17 cases of CN. The majority of CN had been detected by prenatal ultrasound. The ...
KOL-Index: 24 In mice, activated Hedgehog (Hh) signaling induces tumors with myogenic differentiation. In humans, hyperactive Hh signaling due to germline PATCHED1 (PTCH1) mutations has been linked to nevoid basal cell carcinoma syndrome (NBCCS). We report an embryonal rhabdomyosarcoma in a 16-month-old girl with NBCCS and review the literature on myogenic neoplasms in NBCCS, including 8 fetal ...
Known for
8 Fetal Rhabdomyomas | Patched1 Ptch1 Mutations | 3 Rhabdomyosarcomas | Myogenic Differentiation
KOL-Index: 23 Congenital lesions of the scalp must be approached with caution because of the possibility of intracranial extension. Heterotopic neural nodules, a type of neuroectodermal malformation, are particularly dangerous. They manifest in the newborn as a small lump, are often confused with dermoid cysts, and may have a rudimentary stalk that communicates intracranially. The authors retrospectively ...
Known for
Rare Congenital Lesions | Heterotopic Leptomeningeal Tissue | 11 Children | Parietal Occipital Region

From the Departments of *Pathology, †Radiology, †Surgery, and §Gynecology, Children's Hospital and Harvard Medical School, Boston, MA.

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