• Observational Studies
    • Douglas G Douglas
    • Douglas G Douglas: Influence Statistics

      Douglas G Douglas

      Douglas G Douglas

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      University of Oxford | Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK | ...

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      Douglas G Douglas:Expert Impact

      Concepts for whichDouglas G Douglashas direct influence:Observational studies,Consort statement,Randomised trials,Tripod statement,Reporting guidelines,Transparent reporting,Target difference,Blood pressure.

      Douglas G Douglas:KOL impact

      Concepts related to the work of other authors for whichfor which Douglas G Douglas has influence:Randomized controlled trials,Breast cancer,Physical activity,Systematic review metaanalysis,Blood pressure,Observational studies,Heart failure.

      KOL Resume for Douglas G Douglas


      University of Oxford


      Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK


      Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.


      Centre for Statistics in Medicine, University of Oxford, Botnar Research Centre, Oxford, UK

      Center of Statistics in Medicine, University of Oxford, Oxford, United Kingdom


      Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom

      University of Oxford, Oxford, UK


      UK EQUATOR Centre, Centre for Statistics in Medicine, NDORMS, University of Oxford, Windmill Road, Oxford OX3 7LD, UK

      Centre for Statistics in Medicine, University of Oxford, Oxford, England

      Univ. of Oxford, Oxford, United Kingdom

      University of North Carolina School of Medicine, Chapel Hill, NC, USA


      Center for Statistics in Medicine, Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences, University of Oxford Oxford UK

      Centre for Statistics in Medicine,

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      Sample of concepts for which Douglas G Douglas is among the top experts in the world.
      Concept World rank
      star statement #1
      primary outcome design #1
      phase 10 investigators #1
      items based #1
      2004 sample srs #1
      “instructions #1
      two‐dimensional measurements #1
      spirit 2013 explanation #1
      item consort #1
      reviews data #1
      hospital review literature #1
      bf weight length #1
      mortality associates #1
      medical journals internet #1
      gastrooesophageal united kingdom #1
      random sample srs #1
      remark #1
      categorising #1
      domains manuscript #1
      equivalence randomized #1
      treatment outcomes metaanalysis #1
      methods study risk #1
      cosstad #1
      trial target difference #1
      reports included #1
      clinicians interpretation trial #1
      topic design strobe #1
      individual pregnancies #1
      resultscad #1
      protocols published reports #1
      relevant study design #1
      nonprimary publications #1
      medical statistician #1
      discrepancy primary outcome #1
      strobe explanation #1
      deemed essential #1
      statistical guidelines contributors #1
      pubmed quality #1
      humans statistics #1
      prisma oqaq #1
      tripod transparent reporting #1
      qstatin risk #1
      web sites functionality #1
      randomised trials #1
      unrestricted randomization #1
      2015 checklist #1
      confidence scores sensitivity #1
      medical journals #1
      manuscript accuracy #1
      waste inadequate methods #1
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      Prominent publications by Douglas G Douglas

      KOL-Index: 33490

      BACKGROUND: An overwhelming body of evidence stating that the completeness of reporting of randomised controlled trials (RCTs) is not optimal has accrued over time. In the mid-1990s, in response to these concerns, an international group of clinical trialists, statisticians, epidemiologists, and biomedical journal editors developed the CONsolidated Standards Of Reporting Trials (CONSORT) Statement. The CONSORT Statement, most recently updated in March 2010, is an evidence-based minimum ...

      Known for Reporting Trials | Medical Journals | Consolidated Standards | Consort Statement | Completeness Rcts
      KOL-Index: 28629

      BACKGROUND: Asthma and chronic obstructive pulmonary disease (COPD) are common diseases of the airways and lungs that have a major impact on the health of the population. The mainstay of treatment is by inhalation of medication to the site of the disease process. This can be achieved by a number of different device types, which have wide variations in costs to the health service. A number of different inhalation devices are available. The pressurised metered-dose inhaler (pMDI) is the ...

      Known for Inhaler Devices | Clinical Effectiveness | Asthma Copd | Metered Dose | Vaporizers Pulmonary Disease
      KOL-Index: 19649

      BACKGROUND: The World Health Organization recommends that human growth should be monitored with the use of international standards. However, in obstetric practice, we continue to monitor fetal growth using numerous local charts or equations that are based on different populations for each body structure. Consistent with World Health Organization recommendations, the INTERGROWTH-21st Project has produced the first set of international standards to date pregnancies; to monitor fetal ...

      Known for 2 Years | Fetal Growth | International Standards | Study Sites | Motor Development
      KOL-Index: 19297

      BACKGROUND: The design of randomised controlled trials (RCTs) should incorporate characteristics (such as concealment of randomised allocation and blinding of participants and personnel) that avoid biases resulting from lack of comparability of the intervention and control groups. Empirical evidence suggests that the absence of such characteristics leads to biased intervention effect estimates, but the findings of different studies are not consistent.

      OBJECTIVES: To examine the influence ...

      Known for 95 Cri | Randomised Controlled Trials | Trial Characteristics | Allocation Concealment | Intervention Estimates
      KOL-Index: 18847

      BACKGROUND: The CONSORT Statement provides recommendations for reporting randomized controlled trials. We assessed the extent to which leading medical journals that publish reports of randomized trials incorporate the CONSORT recommendations into their journal and editorial processes.

      METHODS: This article reports on two observational studies. Study 1: We examined the online version of 'Instructions to Authors' for 165 high impact factor medical journals and extracted all text mentioning ...

      Known for Consort Statement | Journal Editors | Instructions Authors | Impact Factor | Clinical Trial Registration
      KOL-Index: 17110

      OBJECTIVE: To assess whether the completeness of reporting of health research is related to journals' endorsement of reporting guidelines.

      DESIGN: Systematic review.

      DATA SOURCES: Reporting guidelines from a published systematic review and the EQUATOR Network (October 2011). Studies assessing the completeness of reporting by using an included reporting guideline (termed "evaluations") (1990 to October 2011; addendum searches in January 2012) from searches of either Medline, Embase, and ...

      Known for Reporting Guidelines | Systematic Review Completeness | Equator Network | Journals Endorsement | Guideline Adherence
      KOL-Index: 16946

      BACKGROUND: Retrospective studies provide conflicting interpretations of the effect of inherited genetic factors on the prognosis of patients with breast cancer. The primary aim of this study was to determine the effect of a germline BRCA1 or BRCA2 mutation on breast cancer outcomes in patients with young-onset breast cancer.

      METHODS: We did a prospective cohort study of female patients recruited from 127 hospitals in the UK aged 40 years or younger at first diagnosis (by histological ...

      Known for Brca Mutation | Breast Cancer | Prospective Cohort | 5 Years | Triple Negative
      KOL-Index: 15955

      BACKGROUND: Large differences exist in size at birth and in rates of impaired fetal growth worldwide. The relative effects of nutrition, disease, the environment, and genetics on these differences are often debated. In clinical practice, various references are often used to assess fetal growth and newborn size across populations and ethnic origins, whereas international standards for assessing growth in infants and children have been established. In the INTERGROWTH-21(st) Project, our ...

      Known for Fetal Growth | Newborn Size | 0 Gestation | 14 Weeks | International Standards
      KOL-Index: 15914

      BACKGROUND: Publication of complete trial results is essential if people are to be able to make well-informed decisions about health care. Selective reporting of randomised controlled trials (RCTs) is a common problem.

      OBJECTIVES: To systematically review studies of cohorts of RCTs to compare the content of trial reports with the information contained in their protocols, or entries in a trial registry.

      SEARCH STRATEGY: We conducted electronic searches in Ovid MEDLINE (1950 to August ...

      Known for Published Reports | Registry Entries | Randomised Controlled Trials | Studies Protocols | Selective Reporting
      KOL-Index: 15683

      BACKGROUND: In 2006, WHO published international growth standards for children younger than 5 years, which are now accepted worldwide. In the INTERGROWTH-21(st) Project, our aim was to complement them by developing international standards for fetuses, newborn infants, and the postnatal growth period of preterm infants.

      METHODS: INTERGROWTH-21(st) is a population-based project that assessed fetal growth and newborn size in eight geographically defined urban populations. These groups were ...

      Known for Gestational Age | International Standards | Head Circumference | Newborn Weight | Intergrowth21st Project
      KOL-Index: 15487

      CONTEXT: Selective reporting of outcomes within published studies based on the nature or direction of their results has been widely suspected, but direct evidence of such bias is currently limited to case reports.

      OBJECTIVE: To study empirically the extent and nature of outcome reporting bias in a cohort of randomized trials.

      DESIGN: Cohort study using protocols and published reports of randomized trials approved by the Scientific-Ethical Committees for Copenhagen and Frederiksberg, ...

      Known for Published Articles | Selective Reporting | Empirical Evidence | Primary Outcomes Protocols | Outcomes Outcome
      KOL-Index: 15398

      BACKGROUND: Anticonvulsants are used for pre-eclampsia in the belief they prevent eclamptic convulsions, and so improve outcome. Evidence supported magnesium sulphate as the drug to evaluate.

      METHODS: Eligible women (n=10141) had not given birth or were 24 h or less postpartum; blood pressure of 140/90 mm Hg or more, and proteinuria of 1+ (30 mg/dL) or more; and there was clinical uncertainty about magnesium sulphate. Women were randomised in 33 countries to either magnesium sulphate ...

      Known for Magpie Trial | Eclampsia Women | Magnesium Sulphate | Risk Maternal Death | Randomised Placebo
      KOL-Index: 15141

      OBJECTIVES: To survey the frequency of use of indirect comparisons in systematic reviews and evaluate the methods used in their analysis and interpretation. Also to identify alternative statistical approaches for the analysis of indirect comparisons, to assess the properties of different statistical methods used for performing indirect comparisons and to compare direct and indirect estimates of the same effects within reviews.

      DATA SOURCES: Electronic databases.

      REVIEW METHODS: The ...

      Known for Indirect Comparisons | Competing Interventions | Heparin Placebo | Reviews Effects | Methods Analysis
      KOL-Index: 15106

      OBJECTIVES: The question of whether skeletonized internal thoracic artery harvesting reduces the incidence of sternal wound complications in comparison with the pedicled technique, in the context of single or bilateral internal thoracic arteries, remains controversial. We studied the impact of the internal thoracic artery harvesting strategy on sternal wound complication in the Arterial Revascularization Trial.

      METHODS: Patients enrolled in the Arterial Revascularization Trial (n = 3102) ...

      Known for Internal Thoracic | Sternal Wound Complications | Revascularization Trial | Harvesting Technique | Skeletonized Bilateral

      Key People For Observational Studies

      Top KOLs in the world
      Douglas G Douglas
      observational studies consort statement randomised trials
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      consort statement reporting guidelines randomized controlled trials
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      genetic association studies risk bias dental caries
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      south africa observational studies antiretroviral therapy
      Alessandro Liberati
      breast cancer practice guidelines respiratory tract infections
      Jennifer Marie Tetzlaff
      prisma statement reporting systematic reviews knowledge synthesis

      University of Oxford | Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK | Nuffield Department of Orthopaedics, Rheumatology & Musculoskeletal Sciences,

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