• Disease
  • Observational
  • Observational Studies
  • Douglas G Douglas

    Prominent publications by Douglas G Douglas

    KOL Index score: 33490

    BACKGROUND: An overwhelming body of evidence stating that the completeness of reporting of randomised controlled trials (RCTs) is not optimal has accrued over time. In the mid-1990s, in response to these concerns, an international group of clinical trialists, statisticians, epidemiologists, and biomedical journal editors developed the CONsolidated Standards Of Reporting Trials (CONSORT) Statement. The CONSORT Statement, most recently updated in March 2010, is an evidence-based minimum ...

    Also Ranks for: Reporting Trials |  medical journals |  consolidated standards |  consort statement |  completeness rcts
    KOL Index score: 28629

    BACKGROUND: Asthma and chronic obstructive pulmonary disease (COPD) are common diseases of the airways and lungs that have a major impact on the health of the population. The mainstay of treatment is by inhalation of medication to the site of the disease process. This can be achieved by a number of different device types, which have wide variations in costs to the health service. A number of different inhalation devices are available. The pressurised metered-dose inhaler (pMDI) is the ...

    Also Ranks for: Inhaler Devices |  clinical effectiveness |  asthma copd |  metered dose |  vaporizers pulmonary disease
    KOL Index score: 19649

    BACKGROUND: The World Health Organization recommends that human growth should be monitored with the use of international standards. However, in obstetric practice, we continue to monitor fetal growth using numerous local charts or equations that are based on different populations for each body structure. Consistent with World Health Organization recommendations, the INTERGROWTH-21st Project has produced the first set of international standards to date pregnancies; to monitor fetal ...

    Also Ranks for: 2 Years |  fetal growth |  international standards |  study sites |  motor development
    KOL Index score: 19297

    BACKGROUND: The design of randomised controlled trials (RCTs) should incorporate characteristics (such as concealment of randomised allocation and blinding of participants and personnel) that avoid biases resulting from lack of comparability of the intervention and control groups. Empirical evidence suggests that the absence of such characteristics leads to biased intervention effect estimates, but the findings of different studies are not consistent.

    OBJECTIVES: To examine the influence ...

    Also Ranks for: 95 Cri |  randomised controlled trials |  trial characteristics |  allocation concealment |  intervention estimates
    KOL Index score: 18847

    BACKGROUND: The CONSORT Statement provides recommendations for reporting randomized controlled trials. We assessed the extent to which leading medical journals that publish reports of randomized trials incorporate the CONSORT recommendations into their journal and editorial processes.

    METHODS: This article reports on two observational studies. Study 1: We examined the online version of 'Instructions to Authors' for 165 high impact factor medical journals and extracted all text mentioning ...

    Also Ranks for: Consort Statement |  journal editors |  instructions authors |  impact factor |  clinical trial registration
    KOL Index score: 17110

    OBJECTIVE: To assess whether the completeness of reporting of health research is related to journals' endorsement of reporting guidelines.

    DESIGN: Systematic review.

    DATA SOURCES: Reporting guidelines from a published systematic review and the EQUATOR Network (October 2011). Studies assessing the completeness of reporting by using an included reporting guideline (termed "evaluations") (1990 to October 2011; addendum searches in January 2012) from searches of either Medline, Embase, and ...

    Also Ranks for: Reporting Guidelines |  systematic review completeness |  equator network |  journals endorsement |  guideline adherence
    KOL Index score: 16946

    BACKGROUND: Retrospective studies provide conflicting interpretations of the effect of inherited genetic factors on the prognosis of patients with breast cancer. The primary aim of this study was to determine the effect of a germline BRCA1 or BRCA2 mutation on breast cancer outcomes in patients with young-onset breast cancer.

    METHODS: We did a prospective cohort study of female patients recruited from 127 hospitals in the UK aged 40 years or younger at first diagnosis (by histological ...

    Also Ranks for: Brca Mutation |  breast cancer |  prospective cohort |  5 years |  triple negative
    KOL Index score: 15955

    BACKGROUND: Large differences exist in size at birth and in rates of impaired fetal growth worldwide. The relative effects of nutrition, disease, the environment, and genetics on these differences are often debated. In clinical practice, various references are often used to assess fetal growth and newborn size across populations and ethnic origins, whereas international standards for assessing growth in infants and children have been established. In the INTERGROWTH-21(st) Project, our ...

    Also Ranks for: Fetal Growth |  newborn size |  0 gestation |  14 weeks |  international standards
    KOL Index score: 15914

    BACKGROUND: Publication of complete trial results is essential if people are to be able to make well-informed decisions about health care. Selective reporting of randomised controlled trials (RCTs) is a common problem.

    OBJECTIVES: To systematically review studies of cohorts of RCTs to compare the content of trial reports with the information contained in their protocols, or entries in a trial registry.

    SEARCH STRATEGY: We conducted electronic searches in Ovid MEDLINE (1950 to August ...

    Also Ranks for: Published Reports |  registry entries |  randomised controlled trials |  studies protocols |  selective reporting
    KOL Index score: 15683

    BACKGROUND: In 2006, WHO published international growth standards for children younger than 5 years, which are now accepted worldwide. In the INTERGROWTH-21(st) Project, our aim was to complement them by developing international standards for fetuses, newborn infants, and the postnatal growth period of preterm infants.

    METHODS: INTERGROWTH-21(st) is a population-based project that assessed fetal growth and newborn size in eight geographically defined urban populations. These groups were ...

    Also Ranks for: Gestational Age |  international standards |  head circumference |  newborn weight |  intergrowth21st project
    KOL Index score: 15487

    CONTEXT: Selective reporting of outcomes within published studies based on the nature or direction of their results has been widely suspected, but direct evidence of such bias is currently limited to case reports.

    OBJECTIVE: To study empirically the extent and nature of outcome reporting bias in a cohort of randomized trials.

    DESIGN: Cohort study using protocols and published reports of randomized trials approved by the Scientific-Ethical Committees for Copenhagen and Frederiksberg, ...

    Also Ranks for: Published Articles |  selective reporting |  empirical evidence |  primary outcomes protocols |  outcomes outcome
    KOL Index score: 15398

    BACKGROUND: Anticonvulsants are used for pre-eclampsia in the belief they prevent eclamptic convulsions, and so improve outcome. Evidence supported magnesium sulphate as the drug to evaluate.

    METHODS: Eligible women (n=10141) had not given birth or were 24 h or less postpartum; blood pressure of 140/90 mm Hg or more, and proteinuria of 1+ (30 mg/dL) or more; and there was clinical uncertainty about magnesium sulphate. Women were randomised in 33 countries to either magnesium sulphate ...

    Also Ranks for: Magpie Trial |  eclampsia women |  magnesium sulphate |  risk maternal death |  randomised placebo
    KOL Index score: 15141

    OBJECTIVES: To survey the frequency of use of indirect comparisons in systematic reviews and evaluate the methods used in their analysis and interpretation. Also to identify alternative statistical approaches for the analysis of indirect comparisons, to assess the properties of different statistical methods used for performing indirect comparisons and to compare direct and indirect estimates of the same effects within reviews.

    DATA SOURCES: Electronic databases.


    Also Ranks for: Indirect Comparisons |  competing interventions |  heparin placebo |  reviews effects |  methods analysis
    KOL Index score: 15106

    OBJECTIVES: The question of whether skeletonized internal thoracic artery harvesting reduces the incidence of sternal wound complications in comparison with the pedicled technique, in the context of single or bilateral internal thoracic arteries, remains controversial. We studied the impact of the internal thoracic artery harvesting strategy on sternal wound complication in the Arterial Revascularization Trial.

    METHODS: Patients enrolled in the Arterial Revascularization Trial (n = 3102) ...

    Also Ranks for: Internal Thoracic |  sternal wound complications |  revascularization trial |  harvesting technique |  skeletonized bilateral


    Douglas G Douglas: Influence Statistics

    Sample of concepts for which Douglas G Douglas is among the top experts in the world.
    Concept World rank
    approaches quality assessment #1
    39 nonprimary publications #1
    consort statement trials #1
    fundamento científico #1
    sita bita grafts #1
    tumour marker studies #1
    randomised trials #1
    12 bima #1
    authors improve #1
    designatrial #1
    cochrane cohort #1
    consort flow #1
    andwritingup #1
    rcts lower impact #1
    inadequate methods waste #1
    lancet obstetrics #1
    guidelines heterogeneity #1
    moderatetosubstantial #1
    readers study reports #1
    statistical expertise #1
    assessment repeatability #1
    tmpstudies study #1
    1 variable #1
    humans random #1
    reporting animals #1
    statistical manuscripts #1
    qcancer united kingdom #1
    bias primary studies #1
    qcancer renal #1
    webconsort access #1
    methods clinical measurement #1
    modifications approach #1
    subgroup analyses claims #1
    ureaplasmas cent #1
    discrepancies analyses #1
    items aims #1
    commented examples #1
    multipleindication reviews #1
    24 hour profile #1
    qrisk1 #1
    multiarm trials reporting #1
    fetal size design #1
    avionics pressurometer iii #1
    children school meals #1
    protocol 83 trials #1
    new size charts #1
    interventions nonrandomised studies #1
    guidelines surgical journals #1
    reporting crossover trials #1
    author authors #1

    Key People For Observational Studies

    Top KOLs in the world
    Douglas G Douglas
    observational studies consort statement randomised trials
    David Moher
    consort statement reporting guidelines randomized controlled trials
    Julian P T Higgins
    genetic association studies risk bias dental caries
    Matthias M Egger
    south africa observational studies antiretroviral therapy
    Alessandro Liberati
    breast cancer practice guidelines respiratory tract infections
    Jennifer Marie Tetzlaff
    prisma statement reporting systematic reviews knowledge synthesis

    Douglas G Douglas:Expert Impact

    Concepts for whichDouglas G Douglashas direct influence:Observational studies,  Consort statement,  Randomised trials,  Tripod statement,  Reporting guidelines,  Transparent reporting,  Target difference,  Blood pressure.

    Douglas G Douglas:KOL impact

    Concepts related to the work of other authors for whichfor which Douglas G Douglas has influence:Randomized controlled trials,  Breast cancer,  Physical activity,  Systematic review metaanalysis,  Blood pressure,  Observational studies,  Heart failure.



    Is this your profile? manage_accounts Claim your profile content_copy Copy URL code Embed Link to your profile

    University of Oxford | Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK | Nuffield Department of Orthopaedics, Rheumatology & Musculoskeletal Sciences,