• Disease
  • Coxiella
  • Coxiella Burnetii
  • Didier M Raoult

    Prominent publications by Didier M Raoult

    KOL Index score: 21397

    Bartonella quintana and Bartonella henselae are fastidious gram-negative bacteria responsible for bacillary angiomatosis, trench fever, cat scratch disease, and endocarditis. During a 5-year period, we received 2,043 samples for culture of Bartonella sp. We found Bartonella sp. to be the etiologic agent in 38 cases of endocarditis, 78 cases of cat scratch disease, 16 cases of bacteremia in homeless people, and 7 cases of bacillary angiomatosis. We correlated the results of positive ...

    Also Ranks for: Bartonella Quintana |  patients endocarditis |  bacillary angiomatosis |  scratch disease |  human samples
    KOL Index score: 17589

    Using PCR and an automated laser fluorescent DNA sequencer, we amplified and sequenced a 1,234-bp fragment of the citrate synthase-encoding gene (gltA) of 28 bacteria belonging to the genus Rickettsia. Comparative sequence analysis showed that most of the spotted fever group (SFG) rickettsiae belonged to one of two subgroups. The first subgroup included Rickettsia massiliae, strain Bar 29, Rickettsia rhipicephali, "Rickettsia aeschlimanni," and Rickettsia montana, which have been ...

    Also Ranks for: Phylogenetic Analysis |  citrate synthase |  bacterial rna |  ribosomal genes |  new tool
    KOL Index score: 16875

    BackgroundsCorsica is a French island situated in the Mediterranean Sea. The island provides suitable natural conditions to study disease ecology, especially tick-borne diseases and emerging diseases in animals and ticks. The family Anaplasmataceae is a member of the order Rickettsiales; it includes the genera Anaplasma, Ehrlichia, Neorickettsia and Wolbachia. Anaplasmosis and ehrlichiosis traditionally refer to diseases caused by obligate intracellular bacteria of the genera Anaplasma ...

    Also Ranks for: Domestic Animals |  molecular investigation |  anaplasmataceae species |  sheep cattle |  genera anaplasma
    KOL Index score: 16757

    BACKGROUND: Whipple disease (WD) is a chronic infectious disease caused by Tropheryma whipplei. WD DNA has been found in stool and saliva specimens from patients and asymptomatic carriers.

    METHODS: A total of 4418 samples that were sent to our center for determination of WD were tested by a T. whipplei-specific quantitative polymerase chain reaction (PCR) based on repetitive sequences. Definite WD was diagnosed in 71 patients, including 55 patients with classic WD (defined by positive ...

    Also Ranks for: Whipple Disease |  polymerase chain |  classic wd |  positive pcr |  stool specimens
    KOL Index score: 16720

    A total of 650 ticks, including 13 species from five genera, were collected from animals, from people, or by flagging of the vegetation at sites on the Thai-Myanmar border and in Vietnam. They were tested by PCR to detect DNA of bacteria of the order RICKETTSIALES: Three Anaplasma spp. were detected in ticks collected in Thailand, including (i) Anaplasma sp. strain AnDa465, which was considered a genotype of Anaplasma platys (formerly Ehrlichia platys) and which was obtained from ...

    Also Ranks for: Anaplasma Spp |  ticks collected |  rickettsia thailand |  bacteria dna |  myanmar border
    KOL Index score: 15770

    Little is known about the presence/absence and prevalence of Rickettsia spp, Bartonella spp. and Yersinia pestis in domestic and urban flea populations in tropical and subtropical African countries.

    METHODOLOGY/PRINCIPAL FINDINGS: Fleas collected in Benin, the United Republic of Tanzania and the Democratic Republic of the Congo were investigated for the presence and identity of Rickettsia spp., Bartonella spp. and Yersinia pestis using two qPCR systems or qPCR and standard PCR. In ...

    Also Ranks for: Rickettsia Felis |  yersinia pestis |  bartonella species |  democratic republic |  bacterial humans
    KOL Index score: 15643

    BackgroundOur study aimed to assess the diversity of the species of Anaplasmataceae in Senegal that infect animals and ticks in three areas: near Keur Momar Sarr (northern region), Dielmo and Diop (Sine Saloum, central region of Senegal), and in Casamance (southern region of Senegal).MethodsA total of 204 ticks and 433 blood samples were collected from ruminants, horses, donkeys and dogs. Ticks were identified morphologically and by molecular characterization targeting the 12S rRNA gene. ...

    Also Ranks for: Anaplasma Platys |  molecular characterization |  senegal animals |  species ticks |  diseases dogs
    KOL Index score: 15523

    The prevalences of Bartonella, Rickettsia, and Wolbachia were investigated in 309 cat fleas from France by polymerase chain reaction (PCR) assay and sequencing with primers derived from the gltA gene for Rickettsia, the its and pap31 genes for Bartonella, and the 16S rRNA gene for Anaplasmataceae. Positive PCR results were confirmed by using the Lightcycler and specific primers for the rOmpB of Rickettsia and gltA of Bartonella. R. felis was detected in 25 fleas (8.1%), W. pipientis, an ...

    Also Ranks for: Bartonella Quintana |  molecular detection |  rickettsia felis |  wolbachia pipientis |  fleas france
    KOL Index score: 15446

    BACKGROUND: Obesity is associated with increased health risk and has been associated with alterations in bacterial gut microbiota, with mainly a reduction in Bacteroidetes, but few data exist at the genus and species level. It has been reported that the Lactobacillus and Bifidobacterium genus representatives may have a critical role in weight regulation as an anti-obesity effect in experimental models and humans, or as a growth-promoter effect in agriculture depending on the ...

    Also Ranks for: Lactobacillus Reuteri |  methanobrevibacter smithii |  bifidobacterium animalis |  gut microbiota |  obesity humans
    KOL Index score: 15276

    The emergence of colistin-resistant Klebsiella pneumoniae (CRKP) is a major public health concern worldwide. In this study, the prevalence and molecular basis of colistin resistance in CRKP isolated from healthy individuals and patients in Lao PDR, Thailand, Nigeria and France were investigated. Stool samples were screened by culture for the presence of colistin-resistant Klebsiella spp. Whole-genome sequence analysis was used to decipher the molecular mechanism of colistin resistance in ...

    Also Ranks for: Lao Pdr |  colistin resistance |  klebsiella pneumoniae |  bacterial humans |  isolates study
    KOL Index score: 15015

    Bacteria belonging to the genus Acinetobacter are ubiquitous in soil and water. Only a few species, including Acinetobacter baumannii, and the unnamed Acinetobacter genomic species (gen. sp.) 3 and 13TU, which together with the soil organism Acinetobacter calcoaceticus are combined in the A. calcoaceticus-A. baumannii (Acb) complex, have been recognized as important nosocomial infectious agents. The ecology, epidemiology and pathology of most species are not yet well established. Lack of ...

    Also Ranks for: Acinetobacter Species |  sequence analysis |  rpob gene |  acb complex |  bacterial humans
    KOL Index score: 15001

    BACKGROUND: In recent years, the scope and importance of emergent vector-borne diseases has increased dramatically. In Algeria, only limited information is currently available concerning the presence and prevalence of these zoonotic diseases. For this reason, we conducted a survey of hematophagous ectoparasites of domestic mammals and/or spleens of wild animals in El Tarf and Souk Ahras, Algeria.

    METHODS: Using real-time PCR, standard PCR and sequencing, the presence of Bartonella spp., ...

    Also Ranks for: Coxiella Burnetii |  domestic animals |  northeastern algeria |  souk ahras |  bartonella spp
    KOL Index score: 14972

    BACKGROUND: Matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometry accurately identifies both selected bacteria and bacteria in select clinical situations. It has not been evaluated for routine use in the clinic.

    METHODS: We prospectively analyzed routine MALDI-TOF mass spectrometry identification in parallel with conventional phenotypic identification of bacteria regardless of phylum or source of isolation. Discrepancies were resolved by 16S ribosomal ...

    Also Ranks for: Routine Identification |  mass spectrometry |  ongoing revolution |  ionization time |  assisted laser
    KOL Index score: 14866

    BACKGROUND: Infection with Bartonella quintana can cause trench fever, endocarditis, bacillary angiomatosis, and peliosis. An outbreak of bacteremia due to B. quintana has been reported among homeless people in Seattle, and the seroprevalence is high among homeless people in both the United States and Europe. Body lice are known to be the vectors of B. quintana.

    METHODS: We studied all the homeless people who presented in 1997 to the emergency departments of the University Hospital, ...

    Also Ranks for: Quintana Bacteremia |  homeless patients |  chronic bartonella |  body lice |  trench fever
    KOL Index score: 14620

    By use of the nearly perfectly colinear genomes of Rickettsia conorii and Rickettsia prowazekii, we compared the usefulness of three types of sequences for typing of R. conorii isolates: (i) 5 variable coding genes comprising the 16S ribosomal DNA, gltA, ompB, and sca4 (gene D) genes, which are present in both genomes, and the ompA gene, which is degraded in R. prowazekii; (ii) 28 genes degraded in R. conorii but intact in R. prowazekii, including 23 split and 5 remnant genes; and (iii) ...

    Also Ranks for: Rickettsia Conorii |  multispacer typing |  sequence analysis |  bacterial dna |  variable intergenic


    Didier M Raoult: Influence Statistics

    Sample of concepts for which Didier M Raoult is among the top experts in the world.
    Concept World rank
    humans nhps #1
    negativicoccus massiliensis #1
    fastfung medium #1
    bosea vestrisii #1
    plasmid gc content #1
    automated western #1
    hugonella #1
    massiliprevotella #1
    expert protocols #1
    potential reservoir #1
    genomes massiliensis #1
    shampoo shampoo treatment #1
    rickettsii conorii #1
    african tickbite fever #1
    bartonella rattimassiliensis #1
    epimic #1
    whipplei whipple #1
    positive qpcr #1
    senegalensis gen #1
    boutonneuse #1
    rickettsia hoogstraalii #1
    quintana infections #1
    human colon characteristics #1
    isolated urine #1
    urban individuals #1
    nigerian boy #1
    mediterraneibacter faecis comb #1
    antigenic classification #1
    acinetobacter spp dna #1
    murdochiella #1
    tickborne rickettsiosis #1
    obese french patients #1
    humans advs #1
    serum doxycycline concentration #1
    bacillus rubiinfantis #1
    merdibacter massiliensis #1
    coxiella burnetti infection #1
    cats bacteremia #1
    erythroblast cells #1
    rhamnosus bacteremia #1
    combined hydroxychloroquine #1
    emerging rickettsioses #1
    inoculation eschar #1
    alistipes obesi #1
    mimiviruses pneumonia #1
    bacteroides timonensis #1
    sputnik #1
    acute fever pneumonia #1
    endemic coronaviruses sarscov2 #1
    whipple disease #1

    Key People For Coxiella Burnetii

    Top KOLs in the world
    Didier M Raoult
    coxiella burnetii genome sequence bartonella quintana
    Max Maurin
    francisella tularensis legionella pneumophila coxiella burnetii
    Thomas James Marrie
    acquired pneumonia nova scotia legionella pneumophila
    James E Samuel
    coxiella burnetii shiga toxin guinea pigs
    Robert A Heinzen
    coxiella burnetii host cell chlamydia trachomatis
    Jean Louis Mege
    coxiella burnetii fever endocarditis human monocytes

    Didier M Raoult:Expert Impact

    Concepts for whichDidier M Raoulthas direct influence:Coxiella burnetii,  Genome sequence,  Bartonella quintana,  Giant viruses,  Tropheryma whipplei,  Infective endocarditis,  Fever endocarditis,  Gut microbiota.

    Didier M Raoult:KOL impact

    Concepts related to the work of other authors for whichfor which Didier M Raoult has influence:Gut microbiota,  Infective endocarditis,  Coxiella burnetii,  Acinetobacter baumannii,  Bartonella henselae,  Scrub typhus,  Bacterial dna.



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    Aix-Marseille Univ., Institut de Recherche pour le Développement (IRD), Microbes Evolution Phylogeny and Infections (MEPHI), 27 boulevard Jean Moulin, 13005 Marseille, France | Institut Hospitalo-Universitaire Méditerannée Infection, 19-21 boulevard