 | JeanLouis MD JeanLouis |
Prominent publications by JeanLouis MD JeanLouis
Table of contentsP001 - Sepsis impairs the capillary response within hypoxic capillaries and decreases erythrocyte oxygen-dependent ATP effluxR. M. Bateman, M. D. Sharpe, J. E. Jagger, C. G. EllisP002 - Lower serum immunoglobulin G2 level does not predispose to severe flu.J. Solé-Violán, M. López-Rodríguez, E. Herrera-Ramos, J. Ruíz-Hernández, L. Borderías, J. Horcajada, N. González-Quevedo, O. Rajas, M. Briones, F. Rodríguez de Castro, C. Rodríguez GallegoP003 - Brain protective effects ...
| Also Ranks for: Critically Patients | intensive unit | acute kidney injury | mortality sepsis | risk factors outcomes |
Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008
[ PUBLICATION ]
OBJECTIVE: To provide an update to the original Surviving Sepsis Campaign clinical management guidelines, "Surviving Sepsis Campaign Guidelines for Management of Severe Sepsis and Septic Shock," published in 2004.
DESIGN: Modified Delphi method with a consensus conference of 55 international experts, several subsequent meetings of subgroups and key individuals, teleconferences, and electronic-based discussion among subgroups and among the entire committee. This process was conducted ...
| Also Ranks for: Septic Shock | sepsis campaign | international guidelines | fluid resuscitation 1c | antibiotic therapy |
Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock, 2012
[ PUBLICATION ]
OBJECTIVE: To provide an update to the "Surviving Sepsis Campaign Guidelines for Management of Severe Sepsis and Septic Shock," last published in 2008.
DESIGN: A consensus committee of 68 international experts representing 30 international organizations was convened. Nominal groups were assembled at key international meetings (for those committee members attending the conference). A formal conflict of interest policy was developed at the onset of the process and enforced throughout. The ...
| Also Ranks for: Septic Shock | international guidelines | sepsis campaign | tissue hypoperfusion | ards patients |
OBJECTIVE: To provide an update to the "Surviving Sepsis Campaign Guidelines for Management of Severe Sepsis and Septic Shock," last published in 2008.
DESIGN: A consensus committee of 68 international experts representing 30 international organizations was convened. Nominal groups were assembled at key international meetings (for those committee members attending the conference). A formal conflict of interest policy was developed at the onset of the process and enforced throughout. The ...
| Also Ranks for: Sepsis Campaign | septic shock | ards 1b | tissue hypoperfusion | recommendations patients |
Combined measurements of blood lactate concentrations and gastric intramucosal pH in patients with severe sepsis
[ PUBLICATION ]
OBJECTIVE: To compare the prognostic value of blood lactate concentrations, gastric intramucosal pH, and their combination in patients with severe sepsis.
DESIGN: Prospective, noninterventional study.
SETTING: Medical/surgical intensive care unit of a university hospital.
PATIENTS: The study included 35 consecutive patients (44 to 82 yrs) with severe sepsis as defined by fever or hypothermia (rectal temperature > 38.3 degrees or < 35.5 degrees C), tachycardia (heart rate > 100 ...
| Also Ranks for: Severe Sepsis | lactate concentrations | gastric intramucosal | nonsurvivors survivors | 24 hrs |
BACKGROUND: Although thrombocytopenia in the intensive care unit (ICU) is associated with a poorer outcome, the precise relationship between the time course of platelet counts and the mortality rate has not been well defined.
OBJECTIVE: To describe the time course of the platelet count in relation to the mortality rate in critically ill patients.
DESIGN: Substudy of a prospective, multicenter, observational cohort analysis.
SETTING: Forty ICUs in 16 countries from Europe, America, and ...
| Also Ranks for: Platelet Count | patients thrombocytopenia | survivors nonsurvivors | mortality rate | admission day |
IMPORTANCE: Definitions of sepsis and septic shock were last revised in 2001. Considerable advances have since been made into the pathobiology (changes in organ function, morphology, cell biology, biochemistry, immunology, and circulation), management, and epidemiology of sepsis, suggesting the need for reexamination.
OBJECTIVE: To evaluate and, as needed, update definitions for sepsis and septic shock.
PROCESS: A task force (n = 19) with expertise in sepsis pathobiology, clinical ...
| Also Ranks for: Septic Shock | definitions sepsis | clinical criteria | task force | organ dysfunction |
OBJECTIVES: To examine the performance of the urinary biomarker panel tissue inhibitor of metalloproteinase-2 and insulin-like growth factor-binding protein 7 in patients with sepsis at ICU admission. To investigate the effect of nonrenal organ dysfunction on tissue inhibitor of metalloproteinase-2 and insulin-like growth factor-binding protein 7 in this population.
METHOD: In this ancillary analysis, we included patients with sepsis who were enrolled in either of two trials including 39 ...
| Also Ranks for: Tissue Inhibitor | acute kidney injury | binding protein | patients sepsis | risk stratification |
Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008
[ PUBLICATION ]
OBJECTIVE: To provide an update to the original Surviving Sepsis Campaign clinical management guidelines, "Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock," published in 2004.
DESIGN: Modified Delphi method with a consensus conference of 55 international experts, several subsequent meetings of subgroups and key individuals, teleconferences, and electronic-based discussion among subgroups and among the entire committee. This process was conducted ...
| Also Ranks for: Septic Shock | sepsis campaign | international guidelines | antibiotic therapy | fluid resuscitation |
Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock
[ PUBLICATION ]
OBJECTIVE: In 2003, critical care and infectious disease experts representing 11 international organizations developed management guidelines for severe sepsis and septic shock that would be of practical use for the bedside clinician, under the auspices of the Surviving Sepsis Campaign, an international effort to increase awareness and improve outcome in severe sepsis.
DESIGN: The process included a modified Delphi method, a consensus conference, several subsequent smaller meetings of ...
| Also Ranks for: Septic Shock | severe sepsis | antibiotic therapy | campaign guidelines | pediatric considerations |
INTRODUCTION: Hyperglycemia, hypoglycemia, and increased glycemic variability have each been independently associated with increased risk of mortality in critically ill patients. The role of diabetic status on modulating the relation of these three domains of glycemic control with mortality remains uncertain. The purpose of this investigation was to determine how diabetic status affects the relation of hyperglycemia, hypoglycemia, and increased glycemic variability with the risk of ...
| Also Ranks for: Diabetic Status | diabetes patients | glycemic control | increased risk mortality | hyperglycemia hypoglycemia |
Importance: Abnormal peripheral perfusion after septic shock resuscitation has been associated with organ dysfunction and mortality. The potential role of the clinical assessment of peripheral perfusion as a target during resuscitation in early septic shock has not been established.
Objective: To determine if a peripheral perfusion-targeted resuscitation during early septic shock in adults is more effective than a lactate level-targeted resuscitation for reducing mortality.
Design, ...
| Also Ranks for: Peripheral Perfusion | septic shock | serum lactate levels | resuscitation strategy | organ dysfunction |
Effects of methylene blue on oxygen availability and regional blood flow during endotoxic shock
[ PUBLICATION ]
OBJECTIVE: We hypothesized that methylene blue, by inhibiting the activation of soluble guanylate cyclase mediated by nitric oxide, may reverse systemic hypotension, enhance myocardial function, and improve peripheral distribution of blood flow during endotoxic shock.
DESIGN: Randomized, controlled, acute intervention study.
SETTING: University intensive care laboratory.
SUBJECTS: Twenty-one healthy, anesthetized, mongrel dogs, weighing 26 +/- 4 kg.
INTERVENTIONS: Groups 1 (n = 7) and 2 ...
| Also Ranks for: Methylene Blue | endotoxic shock | blood flow | oxygen availability | arterial pressure |
CONTEXT: Evaluation of trends in organ dysfunction in critically ill patients may help predict outcome.
OBJECTIVE: To determine the usefulness of repeated measurement the Sequential Organ Failure Assessment (SOFA) score for prediction of mortality in intensive care unit (ICU) patients.
DESIGN: Prospective, observational cohort study conducted from April 1 to July 31, 1999.
SETTING: A 31-bed medicosurgical ICU at a university hospital in Belgium.
PATIENTS: Three hundred fifty-two ...
| Also Ranks for: Sofa Score | serial evaluation | 48 hours | mortality rate | icu stay |
CONTEXT: Anemia is a common problem in critically ill patients admitted to intensive care units (ICUs), but the consequences of anemia on morbidity and mortality in the critically ill is poorly defined.
OBJECTIVES: To prospectively define the incidence of anemia and use of red blood cell (RBC) transfusions in critically ill patients and to explore the potential benefits and risks associated with transfusion in the ICU.
DESIGN: Prospective observational study conducted November 1999, with ...
| Also Ranks for: Blood Transfusion | organ dysfunction | critically patients | study anemia | icu mortality |
JeanLouis MD JeanLouis: Influence Statistics
| Concept | World rank |
|---|---|
| distributive shock map | #1 |
| antibody selectin | #1 |
| refractory traumatic hemorrhage | #1 |
| relationship cardiac | #1 |
| ventricular fibrillation emd | #1 |
| sufentanil norway | #1 |
| efficacy recombinant thrombomodulin | #1 |
| sepsis renal denervation | #1 |
| shock intensive | #1 |
| crp eclt | #1 |
| crystalloid colloid ratio | #1 |
| nonsurvivors platelet count | #1 |
| rational intraabdominal infections | #1 |
| temperature hemofiltration | #1 |
| subarachnoid hemorrhage rdw | #1 |
| hydrochloric acid infusion | #1 |
| lymphopaenia admission | #1 |
| endotoxic control | #1 |
| phe2orn8vasotocin | #1 |
| frequency septic shock | #1 |
| cerebral microcirculation sepsis | #1 |
| prowess infusion | #1 |
| degree organ dysfunction | #1 |
| septic shock effects | #1 |
| cap asprf cap | #1 |
| oxygen extraction capabilities | #1 |
| icon plateau pressure | #1 |
| admission icu patients | #1 |
| dobutamine increased | #1 |
| thrombocytopenia day | #1 |
| icu administration | #1 |
| ali avlac | #1 |
| severe sepsis secondary | #1 |
| vancomycin continuous infusion | #1 |
| patients vasoplegic shock | #1 |
| tamponade induced | #1 |
| septic shock hypercapnia | #1 |
| preoperative abnormalities | #1 |
| 13796 | #1 |
| dobutaminetreated animals | #1 |
| evaporative intra | #1 |
| cardiac output do2 | #1 |
| crp levels admission | #1 |
| topic critical education | #1 |
| department intensive | #1 |
| järfälla | #1 |
| suspected disseminated | #1 |
| infection marker | #1 |
| distributive shock patients | #1 |
| effects fluids | #1 |
Key People For Septic Shock
JeanLouis MD JeanLouis:Expert Impact
Concepts for whichJeanLouis MD JeanLouishas direct influence:Septic shock, Severe sepsis, Critically patients, Septic patients, Cardiac surgery, Drotrecogin alfa, Cardiac output, Cardiac arrest.
JeanLouis MD JeanLouis:KOL impact
Concepts related to the work of other authors for whichfor which JeanLouis MD JeanLouis has influence:Septic shock, Severe sepsis, Acute kidney injury, Critically patients, Cardiac surgery, Intensive unit, Critical illness.
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