Prominent publications by Judit Füvesi

KOL Index score: 15526

BACKGROUND: The common symptoms of multiple sclerosis are fatigue, depression, cognitive dysfunction, pain and sexual dysfunction, which influence the health-related quality of life of the patients.

OBJECTIVE: We aimed to determine the correlations between the health-related quality of life, the level of disability, fatigue and depression in glatiramer acetate-treated patients with multiple sclerosis in Hungary.

METHODS: The Hungarian versions of the Multiple Sclerosis Quality of ...

Known for Multiple Sclerosis |  Fatigue Depression |  Glatiramer Acetate |  Quality Life |  Cognitive Dysfunction
KOL Index score: 10763

BACKGROUND: Multiple Sclerosis (MS) causes not only somatic, but also cognitive impairment regardless of the patients׳ age or the course of the disease. The Brief International Cognitive Assessment for MS (BICAMS) test, published in 2011, is a short cognitive questionnaire: a fast, reliable, sensitive and specific tool for the evaluation of the patients׳ cognitive state.

OBJECTIVES: Our primary objective was to assess the validity of the Hungarian version of the BICAMS test. Our ...

Known for Multiple Sclerosis |  Cognitive Impairment |  Bicams Test |  Quality Life |  Fatigue Impact
KOL Index score: 6762

OBJECTIVE: The aim of this study was to determine the prevalence of multiple sclerosis (MS) in the population of Csongrád County, Hungary (400,128 inhabitants) and to determine the functional status (based on the Expanded Disability Status Scale; EDSS) of the patients according to the clinical forms of the disease.

METHODS: The diagnosis was established with the aid of the Poser diagnostic criteria, and the degree of physical disability was determined using the Kurtzke EDSS.


Known for Csongrád County |  Multiple Sclerosis |  Clinical Forms |  Relapsing Remitting |  Chronic Progressive
KOL Index score: 6180

Health-related quality of life measurements are gaining more importance in the study and clinical practice of multiple sclerosis. The aim of our study was the adaptation of the Multiple Sclerosis Quality of Life Instrument (MSQOL-54) in Hungarian. The study was carried out at the Department of Neurology, University of Szeged and two other multiple sclerosis centers. The Hungarian translation of the questionnaire was given to patients at the outpatient units of the neurology departments. ...

Known for Multiple Sclerosis |  Quality Life |  Msqol54 Instrument |  Hungarian Version |  Edss Score
KOL Index score: 6106

BACKGROUND: Health-related quality of life (HRQoL) is lower in people with multiple sclerosis (PwMS) compared to the healthy population, psychological symptoms accompanying multiple sclerosis (MS) have a serious impact on the HRQoL of PwMS. Data regarding the subject, however, remain conflicting.

OBJECTIVES: To evaluate the patients' sociodemographic attributes, education, fatigue, depression, and cognitive impairment level of impact on the HRQoL for the whole cohort as well as comparing ...

Known for Multiple Sclerosis |  Fatigue Depression |  Cognitive Impairment |  Quality Life |  Questionnaires Adult
KOL Index score: 6099

Kynurenic acid (KYNA) is the only known endogenous N-methyl-D-aspartate (NMDA) receptor inhibitor and might therefore come into consideration as a therapeutic agent in certain neurobiological disorders. However, its use as a neuroprotective compound is practically excluded because KYNA does not readily cross the blood-brain barrier (BBB). We recently synthetized a new compound, glucosamine-kynurenic acid (KYNA-NH-GLUC), which is presumed to cross the BBB more easily. In this study, the ...

Known for Kynurenic Acid |  Bbb Kyna |  Therapeutic Agent |  Bloodbrain Barrier |  Excitatory Postsynaptic
KOL Index score: 5638

Tryptophan is one of the essential amino acids, 80% of which is catabolised in the extrahepatic tissues by indoleamine-2,3-dioxygenase (IDO), the rate-limiting enzyme of the kynurenine pathway. Metabolites along the kynurenine pathway have been implicated to play a role in the pathomechanism of neuroinflammatory and neurodegenerative disorders. Changes in the concentration levels of kynurenines can shift the balance to pathological conditions. The ability to influence the metabolism ...

Known for Multiple Sclerosis |  Kynurenine Pathway |  Amyotrophic Lateral |  Neurodegenerative Diseases |  Blood–brain Barrier
KOL Index score: 5365

Tumour necrosis factor alpha (TNF-alpha) is associated with clinical activity in relapsing-remitting multiple sclerosis (RRMS) and the development of progressive disease. Our aim was to investigate the TNF-alpha -376 polymorphism in primary progressive MS (PPMS) patients. Polymerase chain reaction and restriction fragment length polymorphism were carried out on 45 PPMS patients, 45 age and sex-matched RRMS patients and 45 healthy controls (HC). The GG genotype and the guanine allele (G) ...

Known for Multiple Sclerosis |  Necrosis Factor |  Alpha Gene |  Primary Progressive |  −376 Polymorphism
KOL Index score: 5049

PRINCIPLES: Apolipoprotein E (ApoE), an important glycoprotein in the transport, uptake and redistribution of cholesterol, is necessary in nerve tissue repair. The APOE gene (APOE) is involved in neurodegenerative diseases, the best-known association being that between the APOE ε4 allele and Alzheimer's disease. Multiple sclerosis (MS) is a chronic inflammatory neurological disease. The aim of this study was to assess (multicentre assessment) the possible influence of the APOE gene on ...

Known for Primary Progressive |  Ε2 Allele |  Apoe Gene |  Multiple Sclerosis |  Ppms Patients
KOL Index score: 4653

OBJECTIVE: Recent epidemiological studies were mainly based on the Poser or other diagnostic criteria. There have been no previous data from Hungary, which were assessed with the more up-to-date McDonald criteria and which give comparable standardized data from the region.

MATERIALS AND METHODS: Data were collected from the MS Register of the Department of Neurology at the University of Szeged. All possible and definitive patients with MS living in the county on the prevalence day were ...

Known for Multiple Sclerosis |  Csongrád County |  Central Europe |  Clinically Isolated Syndrome |  Mcdonald Criteria
KOL Index score: 4651

BACKGROUND: The 'Multiple Sclerosis Quality of Life Instrument' (MSQOL-54) was recently validated in Hungarian, on more than 400 multiple sclerosis (MS) patients. The aim of the present study was to examine the impact on their overall quality of life (QoL) of the demographic and clinical data on these patients, and their scores on different QoL scales.

METHODS: The Hungarian version of MSQOL-54 was given to patients at the outpatient units at the Department of Neurology, University of ...

Known for Sclerosis Patients |  Life Qol |  Healthrelated Quality |  Mental Health |  Depression Disability
KOL Index score: 3507

OBJECTIVE: We aimed to assess the causes of death, the mortality and survival time of MS patients in Hungary.

PATIENTS AND METHODS: Between 1993 and 2013, 740 patients (10,303person-years) were treated at our Outpatients' Clinic, of which 121 died. The causes of death were established from the pathological records or the medical certificates of the cause of death. The standardized mortality ratios (SMR) were calculated. Survival time was assessed with Gehan-Breslow test.


Known for Multiple Sclerosis |  Primary Progressive |  Death Smr |  Sex Factors |  Relapsing Remitting
KOL Index score: 3136

Multiple Sclerosis (MS) is a chronic disease, but in rare fulminant cases rapid progression may lead to death shortly after diagnosis. Currently there is no diagnostic test to predict disease course. The aim of this study was to identify potential biomarkers/proteins related to rapid progression. We present the case history of a 15-year-old male MS patient. Cerebrospinal fluid (CSF) was taken at diagnosis and at the time of rapid progression leading to the patient's death. Using isobaric ...

Known for Cerebrospinal Fluid |  Proteomic Analysis |  Multiple Sclerosis |  Csf Samples |  Tandem Mass
KOL Index score: 3074

The prevalence of familial aggregation of multiple sclerosis (MS) is estimated between 5 and 10%. Studies emphasize the effect of genetic factors over the environment of the patients in the development of the disease. We investigated familial accumulation of MS in the cases of 1500 patients in five Hungarian MS centers. According to our data, the risk of familial MS in Hungary is lower than in other countries for which literature data are accessible. The literature does not contain any ...

Known for Multiple Sclerosis |  Prevalence Familial |  Genetic Predisposition
KOL Index score: 2985

OBJECTIVES: Not so long ago, a novel phenotypic classification of multiple sclerosis (MS) and revisions to the McDonald diagnostic criteria were published. Good quality, standardized, and therefore comparable epidemiological data from the Central European region altogether are scarce, and data based on the aforementioned criteria are nonexistent; thus, an update is needed.

MATERIALS AND METHODS: Patients residing in Csongrád county with a definitive diagnosis of MS according to the 2017 ...

Known for Multiple Sclerosis |  Prevalence Hungary |  Female Male |  Phenotypic Classification |  Mcdonald Criteria


Judit Füvesi: Influence Statistics

Sample of concepts for which Judit Füvesi is among the top experts in the world.
Concept World rank
379 registered patients #4
mediumrisk country #4
previous data hungary #4
county crude prevalence #4
life glatiramer #4
depression glatiramer #4
rrms development #4
acetate humans life #4
69 relapsingremitting form #4
tnf ppms #5
bicams battery women #5
rrms tnf #5
guanine allele ppms #5
familial hungary #5
edss score sex #5
prevalence crude prevalence #5
predicting factors differences #5
ε4 allele ppms #5
tnfalpha clinical activity #5
45 ppms patients #5
centraleasterneurope #5
cases 1500 patients #5
2 points prevalence #5
crude prevalence males #5
smr median survival #5
factors bicams #5
10303personyears #5
familial accumulation cases #5
countries literature data #5
hungarian centers data #5
bestknown association #5
ppms adenine adult #5
progressive disease aim #5
ppms adenine #5
msrelated smr #5
hungarian rrms #5
women edss score #5
median survival previous #5
prevalence 4370 #5
apoe epsilon status #5
ppms patients smr #5
ppms hungary #5
disease familial accumulation #5
anova bicams battery #6
444 100000 #6
bicams msqol54 #6
kynurenines amyotrophic #6
impairment patients׳ #6
msqol54 fis #6
fis assessments #6

Key People For Multiple Sclerosis

Top KOLs in the world
Alanda K Thompson
multiple sclerosis spinal cord magnetic resonance
Chris H Polman
multiple sclerosis magnetic resonance spinal cord
Fred D Lublin
multiple sclerosis glatiramer acetate monoclonal antibodies
Ludwig Kappos
multiple sclerosis disability progression magnetic resonance
Massimo Filippi
multiple sclerosis magnetic resonance cervical cord
Hans‐Peter Hartung
multiple sclerosis chronic inflammatory schwann cells

Judit Füvesi:Expert Impact

Concepts for whichJudit Füvesihas direct influence:Multiple sclerosis,  Csongrád county,  Hungarian patients,  Cognitive impairment,  Life multiple sclerosis,  Fatigue depression,  Kynurenic acid,  Cerebrospinal fluid.

Judit Füvesi:KOL impact

Concepts related to the work of other authors for whichfor which Judit Füvesi has influence:Multiple sclerosis,  Kynurenic acid,  Cognitive impairment,  Kynurenine pathway,  Processing speed,  Biogenic amines,  Fatigue depression.



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Albert Szent-Györgyi Clinical Centre, Department of Neurology, Faculty of General Medicine, University of Szeged, 6725 Szeged, Hungary;,, (T.B.);, zsofia.kokas@med.u-szeged.huzsiofia, (Z.K.);, sandi.daniel@med.u-szeged

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