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    • John William Kelly
    • John William Kelly: Influence Statistics

      John William Kelly

      John William Kelly

      Victorian Melanoma Service, Alfred Health, Melbourne, VIC 3004, Australia. | Victorian Melanoma Service, Alfred Hospital, Melbourne, Vic., Australia | Cancer Council Australia ...

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      John William Kelly:Expert Impact

      Concepts for whichJohn William Kellyhas direct influence:Cutaneous melanoma,Scalp melanoma,Nodular melanoma,Melanocytic nevi,Shave biopsy,Invasive melanoma,Dermoscopic characteristics,Desmoplastic melanoma.

      John William Kelly:KOL impact

      Concepts related to the work of other authors for whichfor which John William Kelly has influence:Cutaneous melanoma,Skin cancer,Melanocytic nevi,Sun exposure,Early detection,Braf mutation,Lentigo maligna.

      KOL Resume for John William Kelly

      Year
      2021

      Victorian Melanoma Service, Alfred Health, Melbourne, VIC 3004, Australia.

      Cancer Council Australia Melanoma Guidelines Working Party, Sydney, NSW, Australia

      2020

      Monash University Central Clinical School, Melbourne, VIC.

      Victorian Melanoma Service, Alfred Hospital, Melbourne, Victoria, Australia

      2019

      Victorian Melanoma Service, Alfred Hospital, Melbourne, Victoria, Australia.

      Monash University Central Clinical School, Melbourne, VIC

      2018

      The Alfred Hospital, Melbourne, Australia

      Armadale Dermatology, Melbourne, VIC

      2017

      Monash University, Melbourne, VIC

      Victorian Melanoma Service, Alfred Hospital, 3004, Melbourne, Victoria, Australia

      2016

      Victorian Melanoma Service The Alfred Hospital Melbourne Victoria Australia

      2015

      Victorian Melanoma Service, Alfred Hospital, Victoria, Australia.

      2014

      Victorian Melanoma Service, The Alfred Hospital, Alfred Health, Melbourne, VIC.

      2013

      The Alfred Victorian Melanoma Service Melbourne Victoria Australia

      2011

      Victorian Melanoma Service, The Alfred Hospital

      Faculty of Medicine, Monash University, Melbourne, Vic., Australia

      2010

      Departments of Medicine (Drs Ng and Kelly) and Epidemiology & Preventive Medicine (Dr Wolfe and Ms Simpson), Monash University, Melbourne, Victoria, Australia

      Victorian Melanoma Service, The Alfred Hospital, Prahran, Melbourne (Drs Ng, Swain, and Kelly).

      Medicine,

      2008

      Victorian Melanoma Service, The Alfred, Victoria, Australia

      2007

      Victorian Melanoma Service, Alfred Hospital, Melbourne, VIC.

      2006

      Victorian Melanoma Service, The Alfred Hospital, Melbourne (Drs Liu, Dowling, and Kelly)

      2005

      Victorian Melanoma Service and Department of Medicine, Alfred Hospital, Monash University, Victoria, Australia (Dr Kelly)

      2004

      Department of Dermatology, The Alfred Hospital, Melbourne, Victoria, Australia

      2003

      From the Queensland Institute of Medical Research, Post Office, Royal Brisbane Hospital, Queensland (Professor Emeritus)a; Victorian Melanoma Service and Monash University Department of Medicine, Alfred Hospital, Melbourneb; Division of Dermatology, the University of British Columbia, Vancouverc; and Skin Cancer Research Group, School of Public Health and Tropical Medicine, James Cook University, Queensland.d

      Melbourne and Perth, Australia

      1998

      Victorian Melanoma Service and Dermatology Unit, Monash University, Department of Medicine, The Alfred, Commercial Road, Prahran, Victoria 3181, Australia

      1995

      Dermatology Unit and Monash University Department of Medicine, Alfred Hospital, Melbourne, Australia

      1994

      Melbourne, Australia

      Sample of concepts for which John William Kelly is among the top experts in the world.
      Concept World rank
      diagnosis microstaging #1
      review 6721 patients #1
      detection synchronous melanoma #1
      victoria review #1
      kas hemorrhage #1
      regressed nevi #1
      95 excisional biopsy #1
      nodules dermoscopy #1
      falsenegative 519 95 #1
      misdiagnosis punch #1
      histopathologic misdiagnosis #1
      increasing numbers dmn #1
      aggressive melanomas standard #1
      context misdiagnosis #1
      tumour mutation status #1
      88 kas #1
      melanoma incisional punch #1
      site differences density #1
      increasing shave biopsy #1
      inaccuracy partial biopsy #1
      dermatological skin assessments #1
      melanoma cdk4 #1
      dmn melanoma risk #1
      nodular sccs kas #1
      paediatric melanoma victoria #1
      kas glomerular vessels #1
      partial biopsy odds #1
      initial biopsy technique #1
      statewide referral centre #1
      versus ssm #1
      new changed nevi #1
      baseline photography dermatoscopy #1
      prognosis cutaneous #1
      melanoma chnm #1
      pigmented photography remission #1
      nodular scc #1
      misdiagnosis adverse outcome #1
      odds inaccuracy #1
      inaccuracy increased #1
      kas white #1
      complete excisional #1
      3 contrasting latitudes #1
      victorian melanoma service #1
      inaccuracy excisional biopsy #1

      Prominent publications by John William Kelly

      KOL-Index: 11613

      OBJECTIVE: To determine the incidence of new, changed, and regressed nevi and melanomas in a cohort of patients at high risk for melanoma using baseline total body photography and dermatoscopy.

      DESIGN: Cohort study of patients at high risk for melanoma who underwent baseline cutaneous photography between January 1, 1992, and December 31, 1997, and had at least 1 follow-up visit by December 31, 1998.

      SETTING: Private practice rooms of 1 dermatologist in conjunction with a public ...

      Known for Melanoma Patients | Dysplastic Nevi | 50 Years | Nevus Pigmented | Incidence New
      KOL-Index: 10585

      BACKGROUND: Intraepidermal carcinoma (IEC), superficial basal cell carcinoma (sBCC), and psoriasis are common entities that may all present as well-defined, brightly erythematous plaques. Currently, there are limited data on the dermatoscopic features that differentiate these diagnoses.

      OBJECTIVE: We sought to describe the most significant morphologic findings seen on dermatoscopy of IEC, sBCC, and psoriasis, and formulate a diagnostic model based on these features.

      METHOD: We conducted ...

      Known for Basal Cell Carcinoma | Dermatoscopic Features | Limited Data | 150 Cases | Vascular Pattern
      KOL-Index: 9945

      OBJECTIVE: To compare partial and excisional biopsy techniques in the accuracy of histopathologic diagnosis and microstaging of cutaneous melanoma.

      DESIGN: Prospective case series.

      SETTING: Tertiary referral, ambulatory care, institutional practice. Patients Consecutive cases from 1995 to 2006. Interventions Partial and excisional biopsy. Other factors considered were anatomic site, physician type at initial management, hypomelanosis, melanoma subtype, biopsy sample size, multiple ...

      Known for Partial Biopsy | Histopathologic Diagnosis | Tumor Thickness | Cutaneous Melanoma | Punch Shave
      KOL-Index: 9397

      BACKGROUND/OBJECTIVES: Scalp melanoma has a worse prognosis than melanoma elsewhere, though the reasons for this are poorly understood. Current literature describing the clinicopathological associations of scalp melanoma is sparse. This study aims to compare clinical and histological features of scalp melanoma with other cutaneous head and neck melanomas (CHNM).

      METHODS: A cross-sectional study was performed of all primary CHNM cases seen by the Victorian Melanoma Service between 1994 ...

      Known for Scalp Melanoma | Female Head | Worse Prognosis | Sex Factors | Background Objectives
      KOL-Index: 8856

      OBJECTIVE: To describe the diagnostic performance of SolarScan (Polartechnics Ltd, Sydney, Australia), an automated instrument for the diagnosis of primary melanoma.

      DESIGN: Images from a data set of 2430 lesions (382 were melanomas; median Breslow thickness, 0.36 mm) were divided into a training set and an independent test set at a ratio of approximately 2:1. A diagnostic algorithm (absolute diagnosis of melanoma vs benign lesion and estimated probability of melanoma) was developed and ...

      Known for Diagnosis Melanoma | Dermoscopy Image | Sensitivity Specificity | Melanocytic Lesions | Diagnostic Performance
      KOL-Index: 8605

      In melanoma, mutations in KIT are most frequent in acral and mucosal subtypes and rarely reported in cutaneous melanomas particularly those associated with intermittent UV exposure. Conversely melanomas arising within chronic sun damaged skin are considered to harbour KIT mutations at higher rates. To characterize the frequency of KIT mutations in a representative melanoma population, 261 patients from two Australian melanoma centres were prospectively screened for mutations in exons 11, ...

      Known for Kit Mutations | Cutaneous Melanomas | Sun Exposure | Proto Oncogene Proteins | Melanoma Arising
      KOL-Index: 8576

      BACKGROUND: The clinical behaviour and prognosis of primary melanomas harbouring BRAF mutations is not fully understood.

      OBJECTIVES: To investigate the effect of mutation status on primary melanoma growth rate and melanoma-specific survival (MSS).

      METHODS: A prospective cohort of 196 patients with stage I-III primary cutaneous melanoma were followed for a median of 92 months, pre-dating the institution of BRAF inhibitor therapy. Clinicopathological variables were correlated with mutation ...

      Known for Braf Mutation | Primary Melanoma | Hazard Ratios | Prognosis Prospective | Nras Mutant
      KOL-Index: 8315

      BACKGROUND: Various melanocytic lesions are frequently observed. An understanding of phenotypic factors and environmental stimuli that are associated with these lesions may help explain their pathogenesis.

      OBJECTIVE: This study was undertaken to determine the prevalence of atypical nevi, blue nevi, cafe-au-lait macules, congenital nevus-like nevi, halo nevi, nevi spili, nevi 5 mm or more in diameter, and skin-colored melanocytic nevi in a population of schoolchildren and to explore risk ...

      Known for Pigmented Lesions | Atypical Nevi | Nevus Study | Eastern Australian | Prevalence Skin
      KOL-Index: 7846

      OBJECTIVES: To investigate the spectrum of growth rates in melanomas and to identify clinical associations of rapidly growing melanomas.

      DESIGN: Clinical interview, skin examination, and pathology review.

      SETTING: Three tertiary melanoma referral centers and 2 private dermatology practices.

      PATIENTS: A total of 404 consecutive patients with invasive primary cutaneous melanomas.

      MAIN OUTCOME MEASURE: A surrogate for rate of growth in primary invasive melanoma was calculated as the ratio ...

      Known for Growing Melanomas | Rate Growth | Tumor Thickness | Skin Examination | Melanoma Development
      KOL-Index: 7657

      BACKGROUND: Scalp melanomas have more aggressive clinicopathological features than other melanomas and mortality rates more than twice that of melanoma located elsewhere.

      OBJECTIVE: We sought to describe the survival of patients with scalp melanoma versus other cutaneous head and neck melanoma (CHNM), and explore a possible independent negative impact of scalp location on CHNM survival.

      METHODS: A retrospective cohort study was performed of all invasive primary CHNM cases seen at a ...

      Known for Neck Melanoma | Scalp Location | Hazard Ratio | 95 Confidence Interval | Female Head
      KOL-Index: 7533

      BACKGROUND: Nodular melanoma (NM), representing 15% to 30% of all melanomas, constitutes nearly half of all melanomas thicker than 2 mm. Nodular melanoma frequently lacks clinical features seen in other melanoma subtypes and has a faster growth rate. We reviewed a series of cases of NM that was less than 1.3 mm thick to identify historical, clinical, and dermoscopic factors that may facilitate earlier diagnosis of NM, with the hope of reducing its associated morbidity and ...

      Known for Nodular Melanoma | Dermoscopic Characteristics | Dermoscopy Diagnosis | 6 Mm | Early Nm
      KOL-Index: 7524

      The effect of NRAS mutations on the pathological features and clinical outcomes in patients with cutaneous melanoma was compared with that of tumors containing BRAF(V600E) mutations and tumors wild type for both (WT). Clinical outcome data were obtained from a prospective cohort of 249 patients. Mutations involving NRAS and BRAF(V600E) were detected by PCR and were sequence verified. Cox proportional hazards regression was performed to relate NRAS and BRAF mutations to clinical outcome. ...

      Known for Cutaneous Melanoma | Nras Mutation | Hazard Ratio | Prospective Cohort | Thicker Tumors
      KOL-Index: 7520

      PURPOSE: The mutation load in melanoma is generally high compared with other tumor types due to extensive UV damage. Translation of exome sequencing data into clinically relevant information is therefore challenging. This study sought to characterize mutations identified in primary cutaneous melanomas and correlate these with clinicopathologic features.

      EXPERIMENTAL DESIGN: DNA was extracted from 34 fresh-frozen primary cutaneous melanomas and matched peripheral blood. Tumor ...

      Known for Mutation Load | Exome Sequencing | Braf Nras | Clinicopathologic Features | Tumor Types
      KOL-Index: 7475

      BACKGROUND: Case-control studies have identified melanocytic nevi (MN) as the most important phenotypic risk factor for melanoma. A knowledge of any environmental factors that cause MN may facilitate prevention of melanoma.

      OBJECTIVE: This study was undertaken to explore the possible role of ambient solar irradiation in the development of MN in children.

      METHODS: With a standard protocol developed after international consultation, the same medical observers examined children in three ...

      Known for Melanocytic Nevi | Radiationinduced Nevus | 15 Years | Australian Schoolchildren | Development Children
      KOL-Index: 7298

      OBJECTIVES: To explore the clinical associations of thick melanoma and to compare the clinicopathological variables of nodular and superficial spreading types.

      DESIGN: Cross-sectional study of all invasive primary melanomas recorded by the Victorian Cancer Registry for 1998 and those reviewed by the Victorian Melanoma Service between October 1, 1994, and April 31, 1999.

      SETTING: Population-based cancer registry and public hospital-based multidisciplinary melanoma clinic.

      PATIENTS: This ...

      Known for Thick Melanoma | Head Neck | Victorian Cancer Registry | 1 Mm | Tumor Type

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      Victorian Melanoma Service, Alfred Health, Melbourne, VIC 3004, Australia. | Victorian Melanoma Service, Alfred Hospital, Melbourne, Vic., Australia | Cancer Council Australia Melanoma Guidelines Working Party, Sydney, NSW, Australia | Central Clinic

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