• Disease
  • Confocal
  • Confocal Microscopy
  • Aimilios Lallas

    Prominent publications by Aimilios Lallas

    KOL Index score: 13581

    BACKGROUND: Melanoma is the leading cause of skin cancer-associated mortality. The vast majority of newly diagnosed melanomas are confined to the primary cutaneous site. Surgery represents the mainstay of melanoma treatment. Treatment strategies include wide excision of the primary tumour and sentinel lymph node biopsy (SLNB) to assess the status of the regional nodal basin(s). SLNB has become an important component of initial melanoma management providing accurate disease ...

    Also Ranks for: Lymph Node |  cutaneous melanoma |  participants 95 |  wide excision |  review authors
    KOL Index score: 11720

    The European Academy of Dermatology and Venereology (EADV) Task Forces (TFs) on Quality of Life (QoL) and Patient Oriented Outcomes, Melanoma and Non-Melanoma Skin Cancer (NMSC) present a review of the literature and position statement on health-related (HR) QoL assessment in skin cancer patients. A literature search was carried out to identify publications since 1980 that included information about the impact of SC on QoL. Generic, dermatology-specific, cancer-specific, SC-specific, ...

    Also Ranks for: Skin Cancer |  patient oriented outcomes |  life qol |  position paper |  european academy
    KOL Index score: 11555

    Importance: Deep learning convolutional neural networks (CNNs) have shown a performance at the level of dermatologists in the diagnosis of melanoma. Accordingly, further exploring the potential limitations of CNN technology before broadly applying it is of special interest.

    Objective: To investigate the association between gentian violet surgical skin markings in dermoscopic images and the diagnostic performance of a CNN approved for use as a medical device in the European market.

    Design ...

    Also Ranks for: Dermoscopic Images |  diagnostic performance |  melanoma recognition |  skin markings |  roc auc
    KOL Index score: 11434

    BACKGROUND: Whether machine-learning algorithms can diagnose all pigmented skin lesions as accurately as human experts is unclear. The aim of this study was to compare the diagnostic accuracy of state-of-the-art machine-learning algorithms with human readers for all clinically relevant types of benign and malignant pigmented skin lesions.

    METHODS: For this open, web-based, international, diagnostic study, human readers were asked to diagnose dermatoscopic images selected randomly in ...

    Also Ranks for: Learning Algorithms |  human readers |  pigmented skin |  lesion classification |  seborrheic keratosis
    KOL Index score: 11010

    BACKGROUND: Dermoscopy is useful in evaluating skin tumours, but its applicability extends also to the field of inflammatory skin disorders. Plaque psoriasis (PP), dermatitis, lichen planus (LP) and pityriasis rosea (PR) are common inflammatory skin diseases, but little is currently known about their dermoscopic features.

    OBJECTIVES: To determine and compare the dermoscopic patterns associated with PP, dermatitis, LP and PR and to assess the validity of certain dermoscopic criteria in ...

    Also Ranks for: Pityriasis Rosea |  lichen planus |  dermoscopic criteria |  dotted vessels |  dermatitis lp
    KOL Index score: 10823

    BACKGROUND: Convolutional neural networks (CNNs) efficiently differentiate skin lesions by image analysis. Studies comparing a market-approved CNN in a broad range of diagnoses to dermatologists working under less artificial conditions are lacking.

    MATERIALS AND METHODS: One hundred cases of pigmented/non-pigmented skin cancers and benign lesions were used for a two-level reader study in 96 dermatologists (level I: dermoscopy only; level II: clinical close-up images, dermoscopy, and ...

    Also Ranks for: Skin Lesions |  cnn dermatologists |  sensitivity specificity |  neural network |  management decisions
    KOL Index score: 10196

    BACKGROUND: The management of basal cell carcinoma (BCC) depends, among other factors, on its histopathologic subtype. Although dermoscopic criteria of BCC have been investigated, the possible role of dermoscopy in predicting the tumor subtype remains unclear.

    OBJECTIVES: We sought to assess the diagnostic accuracy of dermoscopic criteria for differentiating superficial BCC (sBCC) from other BCC subtypes.

    METHODS: Dermoscopic images of histopathologically confirmed BCCs were ...

    Also Ranks for: Dermoscopic Criteria |  basal cell |  needle carcinoma |  diagnosis sbcc |  bcc subtypes
    KOL Index score: 9816

    Importance: The accuracy of melanoma-specific dermoscopic criteria has been tested mainly in studies including invasive tumors. Scarce evidence exists on the usefulness of these criteria for the diagnosis of melanoma in situ (MIS).

    Objective: To investigate the diagnostic accuracy of dermoscopic criteria for the diagnosis of MIS.

    Design, Setting, and Participants: A diagnostic accuracy study with retrospective patient enrollment was conducted in 3 centers specializing in skin cancer ...

    Also Ranks for: Dermoscopic Criteria |  diagnosis melanoma |  atypical network |  prominent skin markings |  scarce evidence
    KOL Index score: 8788

    Importance: Reflectance confocal microscopy (RCM) improves diagnostic accuracy in skin cancer detection when combined with dermoscopy; however, little evidence has been gathered regarding its real impact on routine clinical workflow, and, to our knowledge, no studies have defined the terms for its optimal application.

    Objective: To identify lesions on which RCM performs better in terms of diagnostic accuracy and consequently to outline the best indications for use of RCM.

    Design, ...

    Also Ranks for: Reflectance Confocal Microscopy |  lesions rcm |  basal cell carcinoma |  dermoscopy diagnosis |  head neck
    KOL Index score: 8771

    BACKGROUND: Dermoscopy improves the recognition of melanoma and Spitz nevus but occasionally melanoma may exhibit a symmetric pattern mimicking Spitz nevus.

    OBJECTIVE: We sought to investigate the likelihood of finding melanoma when excising a symmetric Spitzoid-looking lesion in patients aged 12 years or older.

    METHODS: This study included patients aged 12 years or older with symmetric, Spitzoid-looking lesions that were diagnosed histopathologically as Spitz nevus or melanoma. ...

    Also Ranks for: Spitz Nevus |  12 years |  melanoma patients |  spindle cell |  skin neoplasms
    KOL Index score: 8561

    BACKGROUND: Basosquamous carcinoma (BSC) is a rare and potentially aggressive tumour, characterized by clinical and pathological features of both basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). It is reported to have a nonspecific clinical presentation, which makes naked-eye diagnosis a challenge.

    OBJECTIVES: To describe the dermoscopic patterns of BSC, which may facilitate early diagnosis and accurate management.

    METHODS: This was a retrospective evaluation of clinical and ...

    Also Ranks for: Basosquamous Carcinoma |  bcc scc |  early diagnosis |  dermoscopic pattern |  basal cell
    KOL Index score: 8431

    BACKGROUND: Over the last few years, several articles on dermoscopy of non-neoplastic dermatoses have been published, yet there is poor consistency in the terminology among different studies.

    OBJECTIVES: We aimed to standardize the dermoscopic terminology and identify basic parameters to evaluate in non-neoplastic dermatoses through an expert consensus.

    METHODS: The modified Delphi method was followed, with two phases: (i) identification of a list of possible items based on a systematic ...

    Also Ranks for: General Dermatology |  neoplastic dermatoses |  dermoscopic terminology |  international dermoscopy |  expert consensus
    KOL Index score: 8180

    Sentinel lymph node biopsy has been proposed as a diagnostic method for estimation of the malignant potential of atypical Spitz tumours. However, although cell deposits are commonly detected in the sentinel lymph nodes of patients with atypical Spitz tumours, their prognosis is substantially better than that of patients with melanoma and positive sentinel lymph node biopsies. We did a systematic review of published reports to assess the role of sentinel lymph node biopsy as a prognostic ...

    Also Ranks for: Atypical Spitz Tumours |  sentinel lymph |  node biopsy |  malignant potential |  paediatric population
    KOL Index score: 8117

    Importance: Convolutional neural networks (CNNs) achieve expert-level accuracy in the diagnosis of pigmented melanocytic lesions. However, the most common types of skin cancer are nonpigmented and nonmelanocytic, and are more difficult to diagnose.

    Objective: To compare the accuracy of a CNN-based classifier with that of physicians with different levels of experience.

    Design, Setting, and Participants: A CNN-based classification model was trained on 7895 dermoscopic and 5829 close-up ...

    Also Ranks for: Neural Networks |  skin cancer |  human raters |  dermoscopy diagnosis |  dermoscopic images


    Aimilios Lallas: Influence Statistics

    Sample of concepts for which Aimilios Lallas is among the top experts in the world.
    Concept World rank
    orange structureless #1
    sclerotic clinical #1
    sbcc sft #1
    rash erythematotelangiectatic #1
    follicular findings #1
    morphologic overlap tumours #1
    lpspecific findings lichen #1
    10 frequent diagnoses #1
    dermoscopy morphea #1
    neoplastic dermatoses #1
    features malar #1
    tbp ddd #1
    general dermatology morphology #1
    correspondence dermoscopic #1
    prominent skin markings #1
    predictors isk #1
    addition traditional application #1
    shiny white #1
    initially misclassified tumours #1
    dermoscopy porokeratosis #1
    pathological presence absence #1
    regressive sk remnants #1
    clark spitz recurrent #1
    mole technique #1
    sbcc bowen #1
    photoletter editor #1
    pattern prp #1
    vitiligo perifollicular #1
    pagetoid reticulosis correlation #1
    spitzoid melanoma bapoma #1
    overlap bcc #1
    presence dotted #1
    induction dermoscopy #1
    association lockdowns #1
    fold glomerular vessels #1
    dermoscopy day #1
    dermoscopy vitiligo #1
    new trends dermoscopy #1
    58 acne #1
    fine telangiectasia #1
    nonneoplastic dermatoses #1
    predictors sbcc #1
    select bccs #1
    tapioca sago appearance #1
    valuable mole #1
    solitary brownishred plaque #1
    patients diagnosed melanoma #1
    dermatoscopy early diagnosis #1
    included dermoscopic #1
    spm tbp #1

    Key People For Confocal Microscopy

    Top KOLs in the world
    Milind M Rajadhyaksha
    confocal microscopy human skin mohs surgery
    Salvador González
    confocal microscopy photodynamic therapy polypodium leucotomos
    Roger Yonchien Tsien
    fluorescent proteins living cells protein kinase
    Watt W Webb
    multiphoton microscopy fluorescence correlation cell surface
    Pellacani Pellacani
    confocal microscopy actinic keratosis basal cell
    Caterina Longo
    confocal microscopy basal cell carcinoma melanocytic lesions

    Aimilios Lallas:Expert Impact

    Concepts for whichAimilios Lallashas direct influence:Confocal microscopy,  Basal cell carcinoma,  Dermoscopic features,  Basal cell,  Skin cancer,  Dermoscopic criteria,  Cell carcinoma,  Dermoscopy diagnosis.

    Aimilios Lallas:KOL impact

    Concepts related to the work of other authors for whichfor which Aimilios Lallas has influence:Skin cancer,  Confocal microscopy,  Basal cell carcinoma,  Artificial intelligence,  Dermoscopic features,  Deep learning,  Actinic keratosis.



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    First Department of Dermatology, School of Medicine, Faculty of Health Sciences, Aristotle University, Thessaloniki, Greece. | First Department of Dermatology, Aristotle University, Thessaloniki, Greece | First Department of Dermatology, School of Me