 | Yee Cheun Chan |
Prominent publications by Yee Cheun Chan
Does measuring the median nerve at the carpal tunnel outlet improve ultrasound CTS diagnosis?
[ PUBLICATION ]
INTRODUCTION: Nerve conduction is often regarded as more sensitive than ultrasonography (US) for diagnosing carpal tunnel syndrome (CTS). The diagnostic value of US derives from median nerve enlargement occurring at both ends of the carpal tunnel resulting in a dumbbell-like swelling from carpal tunnel pressure. An important reason for the inferior sensitivity of US may be because measurements are restricted to the carpal tunnel inlet. We investigate the value of including median nerve ...
| Also Ranks for: Median Nerve | carpal tunnel | sensitivity specificity | cts diagnosis | inlet outlet |
BACKGROUND: People with diabetes mellitus (DM) sometimes present with acute or subacute, progressive, asymmetrical pain and weakness of the proximal lower limb muscles. The various names for the condition include diabetic amyotrophy, or diabetic lumbosacral radiculoplexus neuropathies. Some studies suggest that it may be due to immune-mediated inflammatory microvasculitis causing ischaemic damage of the nerves. Immunotherapies would therefore be expected to be beneficial.
OBJECTIVES: We ...
| Also Ranks for: Diabetic Amyotrophy | randomised trials | diabetes mellitus | lower limbs | additional references |
An intraoperatively enlarged engorged median nerve has been described as typical of patients with carpal tunnel syndrome (CTS). Although many studies of CTS have addressed median nerve enlargement, little is known about the usefulness of Doppler methods in detecting median nerve engorgement combined with nerve cross-sectional area (CSA). In a retrospective study of hands referred for evaluation of possible CTS, patients were clinically graded into Highly-likely or Indeterminate CTS. ...
| Also Ranks for: Carpal Tunnel Syndrome | cts patients | ncs csa | median nerve | blood flow |
Antibodies to single glycolipids and glycolipid complexes in Guillain-Barré syndrome subtypes
[ PUBLICATION ]
OBJECTIVE: To comprehensively investigate the relationship between antibodies to single glycolipids and their complexes and Guillain-Barré syndrome subtypes and clinical features.
METHODS: In acute sera from 199 patients with Guillain-Barré syndrome, immunoglobulin G (IgG) antibodies to glycolipids and ganglioside complexes were tested using ELISA against individual antigens from single glycolipids including gangliosides (LM1, GM1, GM1b, GD1a, GalNAc-GD1a, GD1b, GT1a, GT1b, GQ1b) and a ...
| Also Ranks for: Immunoglobulin Igg | ganglioside complexes | acute motor | axonal neuropathy | antibodies gm1 |
OBJECTIVE: Recent studies suggest that high resolution ultrasonography (HRU) is useful in evaluating ulnar neuropathy (UN) at the elbow. These studies do not include UN outside the elbow and lesions related to previous trauma. We investigate diagnostic utility of HRU in UN at any location of traumatic and non-traumatic etiology.
METHODS: Patients with clinically suspected and electrophysiologically defined UN at the elbow and outside the elbow were included. Nerve conduction studies ...
| Also Ranks for: Ulnar Nerve | resolution ultrasonography | studies elbow | sectional area |
Cytoalbuminologic dissociation in Asian patients with Guillain‐Barré and Miller Fisher syndromes
[ PUBLICATION ]
Cerebrospinal fluid (CSF) protein level, cell count, and its relationship to the timing of lumbar puncture were collected from patients with Guillain-Barré syndrome (GBS) and Miller Fisher syndrome (MFS) from various Asian centers. A total of 507 patients with GBS were studied. Overall, 56% had elevated CSF protein level. This was significantly lower than that reported in a recent Dutch study (56% vs 64%). Cytoalbuminologic dissociation was also lower in the Asian cohort (55% vs 64%), ...
| Also Ranks for: Miller Fisher | patients gbs | lumbar puncture | csf protein level | guillainbarré syndrome |
Non-demyelinating, reversible conduction failure in a case of pharyngeal–cervical–brachial weakness overlapped by Fisher syndrome
[ PUBLICATION ]
Pathophysiologically, Guillain-Barré syndrome is divided into demyelinating and axonal subtypes. Recent studies have shown that serial nerve conduction studies (NCSs) are required to differentiate a demyelination-remyelination pathophysiology from one with axonal nodal reversible conduction failure. Cases with an overlap of pharyngeal-cervical-brachial weakness and Fisher syndrome (PCB/FS) are uncommon; the NCS findings of such cases have not been well described and the evolution of the ...
| Also Ranks for: Fisher Syndrome | reversible conduction | continuous spectrum | motor sensory | – brachial |
OBJECTIVE: To study the clinical profile of Guillain-Barré syndrome (GBS) patients who died in 4 Asian countries in order to understand factors underlying any variation in mortality.
METHODS: Retrospectively reviewed medical records of GBS patients who died in 7 hospitals from 4 Asian countries between 2001 and 2012. Baseline characteristics, timing and causes of death were recorded.
RESULTS: A total of 16 out of 261 GBS patients died. The overall mortality rate was 6%, with a range of 0 ...
| Also Ranks for: Barré Syndrome | mortality gbs | mechanical ventilation | baseline characteristics | 77 years |
BACKGROUND: Two small studies had evaluated the efficacy of rTMS in migraine. One tested high frequency rTMS over the dorsolateral prefrontal cortex while the other evaluated 1 Hz rTMS over the vertex.
AIM: To test the feasibility of 10 Hz rTMS of motor cortex as an adjunctive therapy in patients with chronic migraine Materials and Methods: We randomized (2:1 ratio) chronic migraine patients on medical preventive treatment to receive either rTMS or sham therapy for 10 sessions. rTMS (80% ...
| Also Ranks for: Motor Cortex | chronic migraine | 10 hz | frequency rtms | outcome measures |
Electroencephalographic changes and seizures in familial hemiplegic migraine patients with the CACNA1A gene S218L mutation
[ PUBLICATION ]
The S218L CACNA1A mutation has been previously described in two families with familial hemiplegic migraine. We present three siblings with the mutation with the novel association of childhood seizures, and highlight the dynamic changes seen on electroencephalography during hemiplegic migraine attacks. Depressed activity contralateral to the hemiparesis was seen on electroencephalography during acute hemiplegic migraine attacks, which may be due to changes to calcium channels caused by ...
| Also Ranks for: S218l Mutation | hemiplegic migraine | cacna1a gene | calcium channels | families familial |
Medical Undergraduate Survey on Headache Education in Singapore: Knowledge, Perceptions, and Assessment of Unmet Needs
[ PUBLICATION ]
BACKGROUND: There have been no prior studies assessing the status of undergraduate headache training and education in Singapore. Unmet needs of undergraduate medical students in terms of knowledge-practice gaps pertaining to diagnosis and management of headache disorders are unknown. The possible underemphasis of this aspect of the curriculum as compared to other chronic conditions such as diabetes mellitus has also not been ascertained.
OBJECTIVE: The aim of this article is to assess ...
| Also Ranks for: Headache Education | medical students | health knowledge | attitudes practice | diagnosis management |
OBJECTIVE: To highlight the potential usefulness of nerve ultrasonography to identify lymphomatous peripheral nerve infiltration in patients with lymphoma.
METHODS: We performed electrodiagnostic studies and nerve ultrasonography in 3 patients with lymphoma presenting with focal peripheral neuropathy.
RESULTS: In all 3 patients, electrodiagnostic studies proved focal involvement of the peripheral nerves. Ultrasonography showed nerve thickening at sites of electrodiagnostic abnormality. ...
| Also Ranks for: Peripheral Nerve | electrodiagnostic studies | ultrasonography aged | patients lymphoma | nervous neoplasms |
INTRODUCTION: In this study we propose electrodiagnostic criteria for early reversible conduction failure (ERCF) in axonal Guillain-Barré syndrome (GBS) and apply them to a cohort of GBS patients.
METHODS: Serial nerve conduction studies (NCS) were retrospectively analyzed in 82 GBS patients from 3 centers. The criteria for the presence of ERCF in a nerve were: (i) a 50% increase in amplitude of distal compound muscle action potentials or sensory nerve action potentials; or (ii) ...
| Also Ranks for: Barré Syndrome | reversible conduction failure | muscle nerve | gbs patients | conduction studies |
Raised anti-GQ1b antibody is associated with Miller Fisher syndrome, Guillain-Barre syndrome (GBS) with ophthalmoplegia, Bickerstaff's brain stem encephalitis, acute ophthalmoparesis without ataxia and ataxic GBS without opthalmoplegia. We report a rare case of acute ophthalmoplegia associated with anti-GQ1b antibody that also had pupillary areflexia. A 35-year-old Chinese lady presented with external ophthalmoplegia, pupillary areflexia and no other abnormalities of cranial nerves, ...
| Also Ranks for: Acute Ophthalmoplegia | pupillary areflexia | antigq1b antibody | miller fisher syndrome | gbs bickerstaff |
Yee Cheun Chan: Influence Statistics
| Concept | World rank |
|---|---|
| headache curriculum | #2 |
| microvasculitis causing | #2 |
| exclusion lumbosacral | #2 |
| ophthalmoplegia bbe | #3 |
| ultrasound cts diagnosis | #4 |
| cts nerve conduction | #4 |
| verified tarsal | #4 |
| inflammatory microvasculitis | #4 |
| enlargement carpal | #4 |
| pattern nerve abnormality | #4 |
| hands 127 | #4 |
| nerve ultrasound records | #4 |
| clinical picture additional | #4 |
| tibial nerve damage | #4 |
| tts 6 feet | #4 |
| restricted carpal | #4 |
| median nerve specificity | #4 |
| nerve ultrasound cases | #4 |
| fibroosseus tunnel | #4 |
| verified tts | #4 |
| majority patients causation | #4 |
| outlet diagnosing | #4 |
| tts muscle nerve | #4 |
| outlet improve | #4 |
| lateralized lobule | #5 |
| lobule encoding | #5 |
| nerve conduction cts | #5 |
| lobule lateralized | #5 |
| syndrome pcb | #5 |
| viib activations | #5 |
| inferior cerebellum encoding | #5 |
| viiia retrieval | #5 |
| viiia encoding | #5 |
| atypical bickerstaff | #5 |
| vermal lobule viiib | #5 |
| bilateral lobule encoding | #5 |
| quantitative laterality | #5 |
| outlet enlargement | #5 |
| confirmed tts | #5 |
| 127 hands | #6 |
| treatment ilsp | #6 |
| ilsp search | #6 |
| immunotherapy ilsp | #6 |
| asymmetrical pain | #6 |
| amyotrophy search | #6 |
| asymmetrical multifocal weakness | #6 |
| select meeting | #6 |
| methylprednisolone diabetic | #6 |
| plexopathy ilsp | #6 |
| asian patients gbs | #6 |
Key People For Diabetic Amyotrophy
Yee Cheun Chan:Expert Impact
Concepts for whichYee Cheun Chanhas direct influence:Diabetic amyotrophy, Bacterial meningitis, Nerve ultrasound, Fisher syndrome, Chronic migraine, Headache education, Barré syndrome, Tarsal tunnel.
Yee Cheun Chan:KOL impact
Concepts related to the work of other authors for whichfor which Yee Cheun Chan has influence:Median nerve, Carpal tunnel syndrome, Hemiplegic migraine, Chronic inflammatory, Neuromuscular ultrasound, Psychiatric disorders, Miller fisher.
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