• Disease
  • Diabetic
  • Diabetic Amyotrophy
  • Yee Cheun Chan

    Prominent publications by Yee Cheun Chan

    KOL Index score: 12798

    INTRODUCTION: Nerve conduction is often regarded as more sensitive than ultrasonography (US) for diagnosing carpal tunnel syndrome (CTS). The diagnostic value of US derives from median nerve enlargement occurring at both ends of the carpal tunnel resulting in a dumbbell-like swelling from carpal tunnel pressure. An important reason for the inferior sensitivity of US may be because measurements are restricted to the carpal tunnel inlet. We investigate the value of including median nerve ...

    Also Ranks for: Median Nerve |  carpal tunnel |  sensitivity specificity |  cts diagnosis |  inlet outlet
    KOL Index score: 9705

    BACKGROUND: People with diabetes mellitus (DM) sometimes present with acute or subacute, progressive, asymmetrical pain and weakness of the proximal lower limb muscles. The various names for the condition include diabetic amyotrophy, or diabetic lumbosacral radiculoplexus neuropathies. Some studies suggest that it may be due to immune-mediated inflammatory microvasculitis causing ischaemic damage of the nerves. Immunotherapies would therefore be expected to be beneficial.

    OBJECTIVES: We ...

    Also Ranks for: Diabetic Amyotrophy |  randomised trials |  diabetes mellitus |  lower limbs |  additional references
    KOL Index score: 9505

    An intraoperatively enlarged engorged median nerve has been described as typical of patients with carpal tunnel syndrome (CTS). Although many studies of CTS have addressed median nerve enlargement, little is known about the usefulness of Doppler methods in detecting median nerve engorgement combined with nerve cross-sectional area (CSA). In a retrospective study of hands referred for evaluation of possible CTS, patients were clinically graded into Highly-likely or Indeterminate CTS. ...

    Also Ranks for: Carpal Tunnel Syndrome |  cts patients |  ncs csa |  median nerve |  blood flow
    KOL Index score: 7150

    OBJECTIVE: To comprehensively investigate the relationship between antibodies to single glycolipids and their complexes and Guillain-Barré syndrome subtypes and clinical features.

    METHODS: In acute sera from 199 patients with Guillain-Barré syndrome, immunoglobulin G (IgG) antibodies to glycolipids and ganglioside complexes were tested using ELISA against individual antigens from single glycolipids including gangliosides (LM1, GM1, GM1b, GD1a, GalNAc-GD1a, GD1b, GT1a, GT1b, GQ1b) and a ...

    Also Ranks for: Immunoglobulin Igg |  ganglioside complexes |  acute motor |  axonal neuropathy |  antibodies gm1
    KOL Index score: 6475

    OBJECTIVE: Recent studies suggest that high resolution ultrasonography (HRU) is useful in evaluating ulnar neuropathy (UN) at the elbow. These studies do not include UN outside the elbow and lesions related to previous trauma. We investigate diagnostic utility of HRU in UN at any location of traumatic and non-traumatic etiology.

    METHODS: Patients with clinically suspected and electrophysiologically defined UN at the elbow and outside the elbow were included. Nerve conduction studies ...

    Also Ranks for: Ulnar Nerve |  resolution ultrasonography |  studies elbow |  sectional area
    KOL Index score: 5720

    Cerebrospinal fluid (CSF) protein level, cell count, and its relationship to the timing of lumbar puncture were collected from patients with Guillain-Barré syndrome (GBS) and Miller Fisher syndrome (MFS) from various Asian centers. A total of 507 patients with GBS were studied. Overall, 56% had elevated CSF protein level. This was significantly lower than that reported in a recent Dutch study (56% vs 64%). Cytoalbuminologic dissociation was also lower in the Asian cohort (55% vs 64%), ...

    Also Ranks for: Miller Fisher |  patients gbs |  lumbar puncture |  csf protein level |  guillainbarré syndrome
    KOL Index score: 5680

    Pathophysiologically, Guillain-Barré syndrome is divided into demyelinating and axonal subtypes. Recent studies have shown that serial nerve conduction studies (NCSs) are required to differentiate a demyelination-remyelination pathophysiology from one with axonal nodal reversible conduction failure. Cases with an overlap of pharyngeal-cervical-brachial weakness and Fisher syndrome (PCB/FS) are uncommon; the NCS findings of such cases have not been well described and the evolution of the ...

    Also Ranks for: Fisher Syndrome |  reversible conduction |  continuous spectrum |  motor sensory |  – brachial
    KOL Index score: 5337

    OBJECTIVE: To study the clinical profile of Guillain-Barré syndrome (GBS) patients who died in 4 Asian countries in order to understand factors underlying any variation in mortality.

    METHODS: Retrospectively reviewed medical records of GBS patients who died in 7 hospitals from 4 Asian countries between 2001 and 2012. Baseline characteristics, timing and causes of death were recorded.

    RESULTS: A total of 16 out of 261 GBS patients died. The overall mortality rate was 6%, with a range of 0 ...

    Also Ranks for: Barré Syndrome |  mortality gbs |  mechanical ventilation |  baseline characteristics |  77 years
    KOL Index score: 5232

    BACKGROUND: Two small studies had evaluated the efficacy of rTMS in migraine. One tested high frequency rTMS over the dorsolateral prefrontal cortex while the other evaluated 1 Hz rTMS over the vertex.

    AIM: To test the feasibility of 10 Hz rTMS of motor cortex as an adjunctive therapy in patients with chronic migraine Materials and Methods: We randomized (2:1 ratio) chronic migraine patients on medical preventive treatment to receive either rTMS or sham therapy for 10 sessions. rTMS (80% ...

    Also Ranks for: Motor Cortex |  chronic migraine |  10 hz |  frequency rtms |  outcome measures
    KOL Index score: 5045

    The S218L CACNA1A mutation has been previously described in two families with familial hemiplegic migraine. We present three siblings with the mutation with the novel association of childhood seizures, and highlight the dynamic changes seen on electroencephalography during hemiplegic migraine attacks. Depressed activity contralateral to the hemiparesis was seen on electroencephalography during acute hemiplegic migraine attacks, which may be due to changes to calcium channels caused by ...

    Also Ranks for: S218l Mutation |  hemiplegic migraine |  cacna1a gene |  calcium channels |  families familial
    KOL Index score: 4792

    BACKGROUND: There have been no prior studies assessing the status of undergraduate headache training and education in Singapore. Unmet needs of undergraduate medical students in terms of knowledge-practice gaps pertaining to diagnosis and management of headache disorders are unknown. The possible underemphasis of this aspect of the curriculum as compared to other chronic conditions such as diabetes mellitus has also not been ascertained.

    OBJECTIVE: The aim of this article is to assess ...

    Also Ranks for: Headache Education |  medical students |  health knowledge |  attitudes practice |  diagnosis management
    KOL Index score: 4719

    OBJECTIVE: To highlight the potential usefulness of nerve ultrasonography to identify lymphomatous peripheral nerve infiltration in patients with lymphoma.

    METHODS: We performed electrodiagnostic studies and nerve ultrasonography in 3 patients with lymphoma presenting with focal peripheral neuropathy.

    RESULTS: In all 3 patients, electrodiagnostic studies proved focal involvement of the peripheral nerves. Ultrasonography showed nerve thickening at sites of electrodiagnostic abnormality. ...

    Also Ranks for: Peripheral Nerve |  electrodiagnostic studies |  ultrasonography aged |  patients lymphoma |  nervous neoplasms
    KOL Index score: 4380

    INTRODUCTION: In this study we propose electrodiagnostic criteria for early reversible conduction failure (ERCF) in axonal Guillain-Barré syndrome (GBS) and apply them to a cohort of GBS patients.

    METHODS: Serial nerve conduction studies (NCS) were retrospectively analyzed in 82 GBS patients from 3 centers. The criteria for the presence of ERCF in a nerve were: (i) a 50% increase in amplitude of distal compound muscle action potentials or sensory nerve action potentials; or (ii) ...

    Also Ranks for: Barré Syndrome |  reversible conduction failure |  muscle nerve |  gbs patients |  conduction studies
    KOL Index score: 4319

    Raised anti-GQ1b antibody is associated with Miller Fisher syndrome, Guillain-Barre syndrome (GBS) with ophthalmoplegia, Bickerstaff's brain stem encephalitis, acute ophthalmoparesis without ataxia and ataxic GBS without opthalmoplegia. We report a rare case of acute ophthalmoplegia associated with anti-GQ1b antibody that also had pupillary areflexia. A 35-year-old Chinese lady presented with external ophthalmoplegia, pupillary areflexia and no other abnormalities of cranial nerves, ...

    Also Ranks for: Acute Ophthalmoplegia |  pupillary areflexia |  antigq1b antibody |  miller fisher syndrome |  gbs bickerstaff


    Yee Cheun Chan: Influence Statistics

    Sample of concepts for which Yee Cheun Chan is among the top experts in the world.
    Concept World rank
    headache curriculum #2
    microvasculitis causing #2
    exclusion lumbosacral #2
    ophthalmoplegia bbe #3
    ultrasound cts diagnosis #4
    cts nerve conduction #4
    verified tarsal #4
    inflammatory microvasculitis #4
    enlargement carpal #4
    pattern nerve abnormality #4
    hands 127 #4
    nerve ultrasound records #4
    clinical picture additional #4
    tibial nerve damage #4
    tts 6 feet #4
    restricted carpal #4
    median nerve specificity #4
    nerve ultrasound cases #4
    fibroosseus tunnel #4
    verified tts #4
    majority patients causation #4
    outlet diagnosing #4
    tts muscle nerve #4
    outlet improve #4
    lateralized lobule #5
    lobule encoding #5
    nerve conduction cts #5
    lobule lateralized #5
    syndrome pcb #5
    viib activations #5
    inferior cerebellum encoding #5
    viiia retrieval #5
    viiia encoding #5
    atypical bickerstaff #5
    vermal lobule viiib #5
    bilateral lobule encoding #5
    quantitative laterality #5
    outlet enlargement #5
    confirmed tts #5
    127 hands #6
    treatment ilsp #6
    ilsp search #6
    immunotherapy ilsp #6
    asymmetrical pain #6
    amyotrophy search #6
    asymmetrical multifocal weakness #6
    select meeting #6
    methylprednisolone diabetic #6
    plexopathy ilsp #6
    asian patients gbs #6

    Key People For Diabetic Amyotrophy

    Top KOLs in the world
    Sudhansu Chokroverty
    sleep disorders diabetic amyotrophy restless legs syndrome
    David A Krendel
    respiratory failure myasthenia gravis diabetes mellitus
    Linton C Hopkins
    diabetes mellitus muscular dystrophy creatine kinase
    Donal A Costigan
    diabetes mellitus multifocal motor nonvasculitic neuritis
    P James Bonham Dyck
    plasma exchange nerve conduction diabetic polyneuropathy
    Peter James Dyck
    myelinated fibers peripheral neuropathy fiber degeneration

    Yee Cheun Chan:Expert Impact

    Concepts for whichYee Cheun Chanhas direct influence:Diabetic amyotrophy,  Bacterial meningitis,  Nerve ultrasound,  Fisher syndrome,  Chronic migraine,  Headache education,  Barré syndrome,  Tarsal tunnel.

    Yee Cheun Chan:KOL impact

    Concepts related to the work of other authors for whichfor which Yee Cheun Chan has influence:Median nerve,  Carpal tunnel syndrome,  Hemiplegic migraine,  Chronic inflammatory,  Neuromuscular ultrasound,  Psychiatric disorders,  Miller fisher.



    Is this your profile? manage_accounts Claim your profile content_copy Copy URL code Embed Link to your profile

    Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore | Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore;, peiyi.lee@mohh.com.sg, (P.