Heather M Kovar
Prominent publications by Heather M Kovar
Characterization of the immune microenvironment of diffuse intrinsic pontine glioma: implications for development of immunotherapy
[ PUBLICATION ]
Background: Diffuse intrinsic pontine glioma (DIPG) is a uniformly fatal CNS tumor diagnosed in 300 American children per year. Radiation is the only effective treatment and extends overall survival to a median of 11 months. Due to its location in the brainstem, DIPG cannot be surgically resected. Immunotherapy has the ability to target tumor cells specifically; however, little is known about the tumor microenvironment in DIPGs. We sought to characterize infiltrating immune cells and ...
|Known for Immune Microenvironment | Diffuse Intrinsic | Tumor Cells | Dipg Immunotherapy | Pontine Glioma|
Heather M Kovar: Influence Statistics
Key People For Immune Microenvironment
Heather M Kovar:Expert Impact
Concepts for whichHeather M Kovarhas direct influence:Immune microenvironment, Diffuse intrinsic, Intrinsic pontine, Dipg immunotherapy, Dipg cells, Pontine glioma, Glioma dipg, Immunotherapy infant.
Heather M Kovar:KOL impact
Concepts related to the work of other authors for whichfor which Heather M Kovar has influence:Pediatric brain tumors, Diffuse intrinsic, Pontine glioma, Immune contexture, Multimodal immunotherapy, Tumor dissemination, Genetic parameters.
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