Cynthia D Downard: Influence Statistics

Cynthia D Downard

Cynthia D Downard

Division of Pediatric Surgery, Hiram C Polk, Jr, MD Department of Surgery, University of Louisville, Norton Children’s Hospital, Louisville, KY, USA | Nemours Children's ...

Cynthia D Downard: Expert Impact

Concepts for which Cynthia D Downard has direct influence: Brain death , Pediatric surgery , Direct peritoneal resuscitation , Esophageal atresia , Ovarian torsion , Hemorrhagic shock , Benzoic acid .

Cynthia D Downard: KOL impact

Concepts related to the work of other authors for which for which Cynthia D Downard has influence: Congenital diaphragmatic hernia , Esophageal atresia , Bariatric surgery , Necrotizing enterocolitis , Preterm infants , Pediatric patients , Intestinal malrotation .

KOL Resume for Cynthia D Downard

Year
2022

Division of Pediatric Surgery, Hiram C Polk, Jr, MD Department of Surgery, University of Louisville, Norton Children’s Hospital, Louisville, KY, USA

Norton Women's and Children's Hospital

2021

Department of Surgery, Division of Pediatric Surgery, University of Louisville, Louisville, KY, United States

2020

Division of Pediatric Surgery, Hiram C. Polk, Jr, M.D. Department of Surgery, University of Louisville, Louisville, Kentucky

2019

University of Louisville, Department of Surgery, Division of Pediatric Surgery, Louisville, KY, USA.

2018

Department of Surgery, University of Louisville , Louisville, Kentucky.

University of Louisville, Division of Pediatric Surgery, 315 East Broadway, Suite 565, Louisville, KY, 40202, USA. Electronic address:

2017

Division of Pediatric Surgery, Hiram C. Polk, Jr., MD Department of Surgery, University of Louisville, 315 East Broadway, Suite 565, 40202, Louisville, KY, USA

2016

Department of Surgery, University of Louisville, Louisville, KY

Section of Pediatric Surgery, 1540 E. Hospital Drive, Ann Arbor, MI, United States

2015

Division of Pediatric Surgery, Hiram C. Polk, Jr, MD; Department of Surgery, University of Louisville, Louisville, KY

2014

University of Louisville, Louisville, KY, USA

2013

Hiram C. Polk, Jr., MD, Department of Surgery, University of Louisville, Louisville, Kentucky

2012

Kosair Children's Hospital, University of Louisville, Louisville, KY, USA

Pediatric Surgery, University of Louisville, Louisville, KY 40202

2011

Pediatric Surgery, University of Louisville, Louisville, KY 40202, USA

2010

Division of Pediatric Surgery Kosair Children's Hospital Department of Surgery University of Louisville School of Medicine Louisville, Kentucky

2008

Division of Pediatric Surgery, University of Louisville, Louisville, Kentucky 40202, USA.

2007

Division of Pediatric Surgery and the Department of Hematology/Oncology/BMT, Aflac Cancer Center, Emory School of Medicine, Atlanta, GA, USA

2004

Department of Surgery, Children’s Hospital Boston, Boston, MA, USA

2003

Department of Surgery, Children's Hospital, Boston-Harvard Medical School, Boston, MA. Boston, Massachusetts

2002

Department of Surgery, Harvard Medical School, Children's Hospital Boston, Massachusetts

1995

Vanderbilt University School of Medicine Division of Clinical Pharmacology, Departments of Medicine and Pharmacology Nashville Tenn.

Prominent publications by Cynthia D Downard

KOL-Index: 11339 . Importance: Opioids are frequently prescribed to children and adolescents after surgery. Prescription opioid misuse is associated with high-risk behavior in youth. Evidence-based guidelines for opioid prescribing practices in children are lacking. Objective: To assemble a multidisciplinary team of health care experts and leaders in opioid stewardship, review current literature regarding ...
Known for Opioid Prescribing | Children Surgery | Perioperative Period | Review Articles
KOL-Index: 10522 . PURPOSE: Perioperative management of infants with esophageal atresia and tracheoesophageal fistula (EA/TEF) is frequently based on surgeon experience and dogma rather than evidence-based guidelines. This study examines whether commonly perceived important aspects of practice affect outcome in a contemporary multi-institutional cohort of patients undergoing primary repair for the most ...
Known for Esophageal Atresia | Primary Repair | Postoperative Complications | Transanastomotic Tube
KOL-Index: 10058 . OBJECTIVE: To assess the postnatal outcome and complications that arise in infants with the prenatal diagnosis of gastroschisis. METHODS: Prenatal sonograms with the diagnosis of gastroschisis were identified. Maternal age, indication for sonography, gestational age at diagnosis, other sonographic abnormalities, and postnatal outcome were recorded. RESULTS: Twenty-six fetuses at 16 to 36 ...
Known for Postnatal Outcome | Prenatal Diagnosis | Gastroschisis Maternal Age | Newborn Length
KOL-Index: 9799 . OBJECTIVE: The optimal treatment of necrotizing enterocolitis (NEC) is a common challenge for pediatric surgeons. Although many studies have evaluated prevention and medical therapy for NEC, few guidelines for surgical care exist. The aim of this systematic review is to review and evaluate the currently available evidence for the surgical care of patients with NEC. METHODS: Data were ...
Known for Necrotizing Enterocolitis | Nec Premature Infant | Surgical Treatment | Human Milk
KOL-Index: 9157 . BACKGROUND: The maternal variables that affect fetal development and correlate with necrotizing enterocolitis (NEC), the most common gastrointestinal emergency in premature infants, are not well defined. We hypothesized that maternal risk factors were the primary determinant of future development of NEC. METHODS: Patients with NEC were identified from an established NICU database and were ...
Known for Necrotizing Enterocolitis | Maternal Cigarette Smoking | Premature Infant | Medical Records
KOL-Index: 9075 . PURPOSE: The pathophysiology of necrotizing enterocolitis (NEC) includes prematurity, enteral feeds, hypoxia, and hypothermia. We hypothesized that vasoconstriction of the neonatal intestinal microvasculature is the essential mechanistic event in NEC and that these microvascular changes correlate with alterations in mediators of inflammation. METHODS: Sprague-Dawley rat pups were separated ...
Known for Necrotizing Enterocolitis | Intestinal Microcirculation | Nec Animals | Newborn Disease Models
KOL-Index: 8850 . BACKGROUND/PURPOSE: Congenital diaphragmatic hernia (CDH) is a condition associated with significant mortality. This study examines the survival rate of neonates with CDH treated by a multidisciplinary team in a single pediatric hospital. Actual survival rate is compared with predicted outcome based on severity of illness. METHODS: A consecutive series of neonates with CDH was evaluated ...
Known for Congenital Diaphragmatic Hernia | Neonates Cdh | Predicted Survival | Pulmonary Hypertension
KOL-Index: 8210 . BACKGROUND/PURPOSE: Esophageal atresia/tracheoesophageal fistula (EA/TEF) is a rare congenital anomaly lacking contemporary data detailing patient demographics, medical/surgical management and outcomes. Substantial variation in the care of infants with EA/TEF may affect both short- and long-term outcomes. The purpose of this study was to characterize the demographics, management strategies ...
Known for Perioperative Management | Tracheoesophageal Fistula | Esophageal Atresia | Substantial Variation
KOL-Index: 8050 . Severe obesity among youth is an "epidemic within an epidemic" and portends a shortened life expectancy for today's children compared with those of their parents' generation. Severe obesity has outpaced less severe forms of childhood obesity in prevalence, and it disproportionately affects adolescents. Emerging evidence has linked severe obesity to the development and progression of ...
Known for Bariatric Surgery | Severe Obesity | Pediatric Metabolic | Current Evidence
KOL-Index: 7793 . OBJECTIVE: Ovarian torsion in pediatric patients is a rare event and is primarily managed by pediatric general surgeons. Torsion can be treated with detorsion of the ovary or oopherectomy. Oopherectomy is the most common procedure performed by pediatric general surgeons for ovarian torsion. The purpose of this systematic review by the American Pediatric Surgical Association Outcomes and ...
Known for Ovarian Torsion | Pediatric Patients | Torsed Ovary | Child Female
KOL-Index: 7433 . BACKGROUND: Gastroschisis is an increasingly common congenital abdominal wall defect. Due to advances in neonatal critical care and early surgical management, mortality from gastroschisis and associated complications has decreased to less than 10% in most series. However, it has been recognized that the outcome of gastroschisis has a spectrum and that the disorder affects a heterogeneous ...
Known for Neonates Gastroschisis | Parenteral Nutrition | Newborn Infant | Mechanical Ventilation
KOL-Index: 7421 . PURPOSE: Endothelin-1, prostaglandins (PGs), and nitric oxide (NO) have been implicated in the intestinal microvascular dysfunction of necrotizing enterocolitis (NEC). We hypothesized that direct peritoneal resuscitation (DPR) dilates the intestinal microvasculature and improves blood flow independent of these mechanisms. METHODS: Rat pups were assigned by litter to experimental NEC or ...
Known for Blood Flow | Enterocolitis Nec | Nitric Oxide | Ileum Infusions
KOL-Index: 7045 . Vasoconstriction of the neonatal intestinal microvasculature is a central mechanistic event in development of necrotizing enterocolitis. We hypothesized that topical treatment of the intestine with dialysate fluid would ameliorate the vasoconstriction in necrotizing enterocolitis (NEC). NEC was induced in experimental groups. Control animals were delivered vaginally and dam-fed (control ...
Known for Necrotizing Enterocolitis | Blood Flow | Direct Peritoneal Resuscitation | Terminal Ileum
KOL-Index: 7018 . OBJECTIVE: Patients with malrotation, or an intestinal rotation abnormality (IRA), can experience serious adverse events. Increasingly, asymptomatic patients are being diagnosed with malrotation incidentally. Patients with symptomatic malrotation require surgery in an urgent or semiurgent manner to address their symptoms. The treatment of asymptomatic or incidentally discovered malrotation ...
Known for Asymptomatic Malrotation | Laparoscopic Approach | Pediatric Surgical | Intestinal Volvulus
KOL-Index: 6647 . PURPOSE: Preliminary studies have shown aminocaproic acid (AMICAR), an inhibitor of fibrinolysis, reduced the incidence of intracranial hemorrhage and significant surgical site bleeding in patients on extracorporeal membrane oxygenation (ECMO). The purpose of this analysis is to determine if these benefits remain when AMICAR is used in a large population. METHODS: ECMO patients from a ...
Known for Diaphragmatic Hernias | Hemorrhagic Complications | Ecmo Patients | Intracranial Hemorrhage

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Division of Pediatric Surgery, Hiram C Polk, Jr, MD Department of Surgery, University of Louisville, Norton Children’s Hospital, Louisville, KY, USA | Nemours Children's Health, Wilmington, DE, USA, and Sidney Kimmel Medical College at Thomas Jeffers