Oliver GrundnesShow email address
From Kysthospitalet in Hagevik, Orthopedic Department, Haukeland University Hospital (I.M.A., E.H., F.R., K.I.), and the Department of Clinical Medicine, University of Bergen ...
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Oliver Grundnes:Expert Impact
Concepts for whichOliver Grundneshas direct influence:Disc prosthesis,Blood flow,Fracture healing,Lumbar spinal stenosis,Cognitive intervention,Chronic low,Dural sac area,Degenerative disc.
Oliver Grundnes:KOL impact
Concepts related to the work of other authors for whichfor which Oliver Grundnes has influence:Fracture healing,Lumbar fusion,Chronic low,Intramedullary nailing,Bone repair,Spine surgery,Distraction osteogenesis.
KOL Resume for Oliver Grundnes
From Kysthospitalet in Hagevik, Orthopedic Department, Haukeland University Hospital (I.M.A., E.H., F.R., K.I.), and the Department of Clinical Medicine, University of Bergen (E.H., F.R., K.I.), Bergen, Møre and Romsdal Hospital Trust, Ålesund Hospital, Orthopedic Department, Ålesund (E.H.), the Oslo Center for Biostatistics and Epidemiology, Research Support Services (M.W.F.), the Research and Communication Unit for Musculoskeletal Health, Division of Clinical Neuroscience (K.S.), and the Department of Physical Medicine and Rehabilitation (J.I.B.), Oslo University Hospital, the Department of Physiotherapy, Oslo Metropolitan University (K.S.), the Medical Faculty (J.I.B.), the Division of Radiology and Nuclear Medicine, Institute of Clinical Medicine, Faculty of Medicine (T.B.), and the Institute of Clinical Medicine (H. Banitalebi), University of Oslo, Akershus University Hospital, Orthopedic Department (O.G.), Radiology, Unilabs Radiology (K.R.H.A.), and the Department of Radiology and Nuclear Medicine (T.B.) and the Division of Orthopedic Surgery (C.H.), Oslo University Hospital Ullevål, Oslo, the Institute of Clinical Medicine, University of Tromsø-the Arctic University of Norway, and the Norwegian Registry for Spine Surgery, University Hospital of North Norway, Tromsø (T.S.), the Orthopedic Department (E.F.) and the Department of Neurosurgery (C.W.), Stavanger University Hospital, and the Department of Quality and Health Technology, Faculty of Health Sciences, University of Stavanger (C.W.), Stavanger, and the Department of Diagnostic Imaging, Akershus University Hospital, Lorenskog (H. Banitalebi) - all in Norway; and the Spine Surgery Team, Department of Orthopedics, Sahlgrenska University Hospital, and the Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden (H. Brisby).
Department of Orthopedics, Akershus University Hospital, Oslo, Norway
Department of Orthopedics, Akershus University Hospital, N-1474, Lørenskog, Oslo, Norway
Department of Orthopedics, Akershus University Hospital, Lørenskog, Norway
Aleris Hospital, Oslo, Norway; and
Aleris Hospital, Oslo, Norway.
Hjelp24, Nimi, Oslo, Norway
Hjelp24, Nimi, Oslo Sognsveien 75 D, 0855 Oslo
Department of Orthopaedics, Oslo University Hospital, and University of Oslo, Oslo, Norway (Mr Wilkens and Drs Grundnes, Hellum, and Storheim)
Department of Orthopedics, Ullevaal University Hospital, Oslo, Norway
*Department of Orthopedic Surgery and ‡Biomechanical Laboratory, Institute of Clinical Medicine, University Hospital of Tromsoe; †Department of Orthopedic Surgery, Ullevål Hospital; and §Department of Orthopedics, National Hospital, Oslo, Norway
Departments of Orthopedic Surgery, 1Institute of Clinical Medicine, NO-9038 University Hospital of Tromso, Diacones Hospital, NO-5009 Bergen, Ulleval Hospital, NO-0450 Oslo, National Hospital, NO-0570 Oslo, Norway. Correspondence: Dr. Olav Reikeras. E-mail:
Departments of Orthopedics, Institute of Clinical Medicine, University of Tromsø and National Hospital, University of Oslo, Norway, NO
Department of Orthopedics and Surgical Research, National Hospital, NO-0570, Oslo, Norway
Department of Orthopedics, Institute of Clinical Medicine, University Hospital, Tromsoe, Norway; and *Departments of Orthopedics and Surgical Research, National Hospital, Oslo, Norway
Department of Orthopedics, Institute of Clinical Medicine, University Hospital, Tromsø, Norway
Department of Orthopedics, Institute of Clinical Medicine, University Hospital, N-9012, Tromso, Norway, Tel +47-77 62 6000, Fax -77 62 6042
Department of Orthopedics, Institute of Clinical Medicine, University Hospital, N-9012, Tromse, Norway
Department of Orthopedics, Institute of Clinical Medicine, University Hospital, N-9012, Tromsø, Norway, Tel +47-83 26000, Fax -83 26042
Department of Orthopedics, Institute of Clinical Medicine, University Hospital, N-9012, London, UK
From the Departments of Anesthestology Drs. Herroy and Bjertnæs and Physology Mr. Grundnes and Dr. Mjøwy University of Tromsø Norway.
†Department of Physiology, Institute of Medical Biology, University of Tromsø, Norway
|fractures periosteal attachment||#1|
|femoral bone macrophages||#1|
|differences qualitative healing||#1|
|area healing area||#1|
|bending moment periosteum||#1|
|biomechanical phenomena bony||#1|
|area original defect||#1|
|16mm steel pins||#1|
|periosteal stripping segment||#1|
|fractures attached periosteum||#1|
|immature hypertrophic callus||#1|
|8mm intermediary fragment||#1|
|healing segmental fractures||#1|
|osteotomy femoral bone||#1|
|fractures stripped periosteum||#1|
|lesser weight increase||#1|
|planimetric analysis differences||#1|
|local activation macrophages||#1|
|healing ratio area||#1|
|periosteal attachment fractures||#1|
|defect planimetric analysis||#1|
|attached periosteum study||#1|
|segmental flow fractures||#1|
|study segmental fractures||#1|
|differences healing ratio||#1|
|total flow groups||#2|
|intramedullary male prostheses||#2|
|callus production moment||#2|
|groups nailed bones||#2|
|modest intramedullary reaming||#2|
|bending moment rigidity||#2|
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Prominent publications by Oliver Grundnes
Surgery with disc prosthesis versus rehabilitation in patients with low back pain and degenerative disc: two year follow-up of randomised study
[ PUBLICATION ]
OBJECTIVE: To compare the efficacy of surgery with disc prosthesis versus non-surgical treatment for patients with chronic low back pain.
DESIGN: A prospective randomised multicentre study.
SETTING: Five university hospitals in Norway.
PARTICIPANTS: 173 patients with a history of low back pain for at least one year, Oswestry disability index of at least 30 points, and degenerative changes in one or two lower lumbar spine levels (86 patients randomised to surgery). Patients were treated ...
|Known for Disc Prosthesis | Low Pain | Surgery Patients | Oswestry Disability | Prolo Scale|
Lumbar instrumented fusion compared with cognitive intervention and exercises in patients with chronic back pain after previous surgery for disc herniation: A prospective randomized controlled study
[ PUBLICATION ]
The effectiveness of lumbar fusion for chronic low back pain after surgery for disc herniation has not been evaluated in a randomized controlled trial. The aim of the present study was to compare the effectiveness of lumbar fusion with posterior transpedicular screws and cognitive intervention and exercises. Sixty patients aged 25-60 years with low back pain lasting longer than 1 year after previous surgery for disc herniation were randomly allocated to the two treatment groups. ...
|Known for Cognitive Intervention | Disc Herniation | Previous Surgery | Patients Chronic Pain | Lumbar Fusion|
Effect of Glucosamine on Pain-Related Disability in Patients With Chronic Low Back Pain and Degenerative Lumbar Osteoarthritis: A Randomized Controlled Trial
[ PUBLICATION ]
CONTEXT: Chronic low back pain (LBP) with degenerative lumbar osteoarthritis (OA) is widespread in the adult population. Although glucosamine is increasingly used by patients with chronic LBP, little is known about its effect in this setting.
OBJECTIVE: To investigate the effect of glucosamine in patients with chronic LBP and degenerative lumbar OA.
DESIGN, SETTING, AND PARTICIPANTS: A double-blind, randomized, placebo-controlled trial conducted at Oslo University Hospital Outpatient ...
|Known for Chronic Low | 1 Year | Lumbar Osteoarthritis | Pain Lbp | Oral Glucosamine|
[ PUBLICATION ]
In 30 rats, closed bilateral fractures of the femur were produced. On the left side intramedullary reaming was performed to 1.6 mm, and the fracture fixed-with a steel pin with a diameter of 1.6 mm. On the right side the femoral canal was reamed to 2.0 mm and a hollow steel tube with a diameter of 2.0 mm was used for fixation. An additional 8 rats were used to obtain mechanical, dimensional and flow data on intact femurs, and another 10 rats were used to study the acute flow changes ...
|Known for Fracture Healing | Blood Flow | 16 Mm | Intramedullary Reaming | Cortical Bone|
Study-protocol for a randomized controlled trial comparing clinical and radiological results after three different posterior decompression techniques for lumbar spinal stenosis: the Spinal Stenosis Tr
[ PUBLICATION ]
BACKGROUND: There are several posterior decompression techniques for lumbar spinal stenosis (LSS). There is a trend towards performing less invasive surgical procedures, but no multicentre randomized controlled trials have evaluated the relative efficacy of these techniques at short and long-term.
|Known for Lumbar Spinal Stenosis | Nordsten Study | Controlled Trial | Decompression Techniques | Neurogenic Claudication|
OBJECTIVES: The treatment of tibial fractures associated with severe soft tissue injury remains a challenge. The objective of our experiment was to ascertain the influence of standardized muscle injuries on fracture healing in a nailed rat tibial fracture model. We hypothesized that a severe crush injury of leg muscles might not be as deleterious to fracture healing as total loss of a large muscle segment.
STUDY DESIGN: A randomized study in male Wistar rats with a diaphyseal ...
|Known for Fracture Healing | Muscle Injury | 4 Weeks | Soft Tissue | Osteotomy Rats|
BACKGROUND: In patients with lumbar spinal stenosis and degenerative spondylolisthesis, it is uncertain whether decompression surgery alone is noninferior to decompression with instrumented fusion.
METHODS: We conducted an open-label, multicenter, noninferiority trial involving patients with symptomatic lumbar stenosis that had not responded to conservative management and who had single-level spondylolisthesis of 3 mm or more. Patients were randomly assigned in a 1:1 ratio to undergo ...
|Known for Lumbar Spondylolisthesis | Decompression Fusion | Leg Pain | Surgery Degenerative | Spinal Stenosis|
[ PUBLICATION ]
In male Wistar rats, a transverse osteotomy at the midshaft of the femur was made, and the acute effects on bone flow were measured before and after reaming. Flow and mechanical variables in the healing bones were measured at 4, 8, and 12 weeks following osteotomy. Osteotomy reduced total bone blood flow by about 50 percent, and cortical flow in the diaphysis by approximately 40 percent. Cortical flow was equally diminished in the mid-diaphysis and in the osteotomy area, and no ...
|Known for Blood Flow | Mechanical Properties | Healing Bone | Callus Area | 4 Weeks|
We assessed the effects of periosteal detachment from bone and musculature on the healing of diaphyseal fracture. In 30 male Wistar rats we produced a partial osteotomy, which was manually broken in the middiaphysis of the left femur. All fractures were reamed and stabilized with an 1.6 mm steel pin. The animals were randomly assigned to 3 groups. In group 1, a subperiosteal detachment between cortex and periost was created in the middle third of the diaphysis. An extraperiosteal ...
|Known for Fracture Healing | Extraperiosteal Detachment | Callus Formation | 3 Groups | 4 Weeks|
The present study was undertaken to assess the effect of periosteal detachment upon the healing of segmental diaphyseal fractures. In rats we produced two standardized partial osteotomies with an 8-mm intermediary fragment in the femoral diaphysis. The osteotomies were then manually broken, retaining the periosteal and muscular attachment on the medial side in one group. In the other group, the segment was stripped of periosteum circumferentially. The fractures were stabilized with ...
|Known for Periosteal Stripping | Periosteum Rats | 4 Weeks | Segmental Fractures | Blood Flow|
[ PUBLICATION ]
Abstract The effect of graded exchange reaming and intramedullary nailing on a non-union model in the rat femur was studied by clinical, radiological, bone mineralisation and biomechanical methods. A standardised procedure was first developed to create a non-union that did not heal and in which non-union developed consistently. In 30 male Wistar rats a standardised osteotomy was produced in the left femur diaphysis. The fractures were reamed to 1.5 mm and nailed with a soft polyethylene ...
|Known for Union Fractures | Nailing Bone | Femur Fracture | 12 Weeks | Fixation Intramedullary|
Bilateral closed femoral fractures were produced in two groups of rats. Reaming was made from the trochanteric area before fracture, and the fractures were stabilized by intramedullary pinning. In one (hematoma) group, both femurs were exposed subperiosteally at the midshaft prior to fracture. At one side, the hematoma was evacuated 30 min following fracture, at the other side the hematoma was left undisturbed. In the other (periosteal) group, the femur was exposed subperiosteally at one ...
|Known for Fracture Healing | 4 Weeks | Periosteum Rats | Biomechanical Phenomena | Bending Moment|
Prognostic Factors of Prolonged Disability in Patients With Chronic Low Back Pain and Lumbar Degeneration in Primary Care
[ PUBLICATION ]
STUDY DESIGN: A cohort study with 1-year follow-up.
OBJECTIVE: To identify prognostic factors in patients with chronic nonspecific low back pain (LBP).
SUMMARY OF BACKGROUND DATA: The factors (e.g., sociodemographical, low back-related, radiological, and biological) associated with persistent pain and disability for patients with chronic nonspecific LBP are uncertain. Furthermore, sparse information exists about the relationship between biological factors like impaired fasting glucose ...
|Known for Chronic Low | Pain Disability | Year Patients | Lumbar Osteoarthritis | Disc Degeneration|
Predictors of outcome after surgery with disc prosthesis and rehabilitation in patients with chronic low back pain and degenerative disc: 2-year follow-up
[ PUBLICATION ]
PurposeA prospective study to evaluate whether certain baseline characteristics can predict outcome in patients treated with disc prosthesis or multidisciplinary rehabilitation.MethodsSecondary analysis of 154 patients with chronic low back pain (LBP) for at least 1 year and degenerative discs originally recruited for a randomized trial. Outcome measures were Oswestry Disability Index (ODI) dichotomized to < or ≥15 points improvement and whether subjects were working at 2-year follow-up. ...
|Known for Disc Prosthesis | Year Follow | Chronic Low | Modic Type | Oswestry Disability|
We examined the acute effects of increasing degree of intramedullary reaming on bone blood flow in 27 male Wistar rats by use of the microsphere method. A marginal reduction in total bone and cortical bone blood flow was seen when the femoral canal was reamed to a diameter smaller than the medullary cavity (1.5 mm). Reaming equal to the antero-posterior diameter (1.8 mm) halved total bone flow and reduced cortical blood flow by one third. Reaming equal to the transverse diameter (2.1 mm) ...
|Known for Blood Flow | Intramedullary Reaming | Cortical Bone | Medullary Cavity | Femoral Canal|