Johanna Mäkelä

Johanna Mäkelä

Department Of Teacher Education, University Of Helsinki, P. O. Box 8, Fi-00014 University Of Helsinki, Finland

Direct Impact

Concepts for which Johanna Mäkelä has direct influence:

dopaminergic neurons
weight management
functional foods
food consumption
oxidative stress
meal complexity
carbon footprint

External impact

Concepts related to the work of other authors for which Johanna Mäkelä has influence:

villous cytotrophoblast
cooking skills
video technology
apoptosis protein
stem cells
transgenic mice
epigallocatechin gallate

Prominent publications by Johanna Mäkelä

KOL-Index: 28 PACAP is a neuropeptide with a multitude of functions on different cell types and organs including brain tissue. PACAP is relatively highly expressed in embryonic brain indicating a role in neuronal development. Particularly PACAP is expressed in the subventricular zone of lateral ventricles and in the dentate gyrus of hippocampus harboring the neural stem/progenitor cells (NPCs) that give ...
Known for
Lateral Ventricles | Pacap Expressed | Npcs Brain | Subventricular Zone
KOL-Index: 28 BACKGROUND: Neural progenitor cells (NPCs) in the developing neuroepithelium are regulated by intrinsic and extrinsic factors. There is evidence that NPCs form a self-supporting niche for cell maintenance and proliferation. However, molecular interactions and cell-cell contacts and the microenvironment within the neuroepithelium are largely unknown. We hypothesized that cellular proteases ...
Known for
Factor Activator | Hepatocyte Growth | Bone Morphogenetic | Neural Progenitor
KOL-Index: 22 Parkinson’s disease (PD is a progressive neurological disorder characterized by the degeneration and death of midbrain dopamine and non-dopamine neurons in the brain leading to motor dysfunctions and other symptoms, which seriously influence the quality of life of PD patients. The drug L-dopa can alleviate the motor symptoms in PD, but so far there are no rational therapies targeting the ...
Known for
Substances Trophic | Modifying Therapies | Neurons Models
KOL-Index: 22 This exploratory article examines the novel term food sense and informal learning in the context of home cooking. Its theory draws from Dewey's work and from his notions of reflexive thought and action. The data consist of a transcribed audio recording of an in-depth, video-based, stimulated-recall (SR) interview. The auto-ethnographic videos were used to stimulate conversation during the ...
Known for
Context Theory | Food Informal | Ways Action
KOL-Index: 20 Mitochondrial dysfunctions accompany several neurodegenerative disorders and contribute to disease pathogenesis among others in Parkinson's disease (PD). Peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) is a major regulator of mitochondrial functions and biogenesis, and was suggested as a therapeutic target in PD. PGC-1α is regulated by both transcriptional and ...
Known for
Dopaminergic Neuron Viability | Nad-Dependent Deacetylase Sirtuin-1 Sirt1 | Fatty Acid Metabolism | Mitochondrial Respiratory Capacity
KOL-Index: 19 After severe myocardial infarction (MI), heart failure results from ischemia, fibrosis, and remodeling. A promising therapy to enhance cardiac function and induce therapeutic angiogenesis via a paracrine mechanism in MI is myoblast sheet transplantation. We hypothesized that in a rat model of MI-induced chronic heart failure, this therapy could be further improved by overexpression of the ...
Known for
Therapy Rats | L6-Hgf | Autocrine | L6 Myoblast Sheet-Derived Paracrine
KOL-Index: 18 Peroxisome proliferator-activated receptor gamma coactivator-1α (PGC-1α) is a transcriptional coactivator involved in the regulation of mitochondrial biogenesis and cell defense. The functions of PGC-1α in physiology of brain mitochondria are, however, not fully understood. To address this we have studied wild-type and transgenic mice with a two-fold overexpression of PGC-1α in brain ...
Known for
Hippocampus Pgc-1α | Cultured Hippocampal Neurons | Enhanced Neuronal Viability | Two-Fold Overexpression
KOL-Index: 16 Treatment with resveratrol (RSV) has been shown to protect vulnerable neurons after various brain injuries and in neurodegenerative diseases. The mechanisms for the effects of RSV in brain are not fully understood, but RSV may affect the expression of various gene products. RSV is structurally related to the synthetic estrogen, diethylstilbestrol so the effects of RSV may be gender-specific. ...
Known for
Cells Rsv | Transporter Striatum | Receptors Involved | Regulation Dopamine
KOL-Index: 16 The article analyses engagements in home cooking from a practice theoretical perspective. The focus on engagements reveals what people regard as worthy of doing and as appropriate cooking performances in specific everyday situations. For producing a more nuanced account of situationally appropriate cooking, the theoretical perspective is complemented by Thévenot’s regimes – familiarity, ...
Known for
Performances Interviews | Cooking Theoretical
KOL-Index: 14 The aim of the study, on which this paper is based, was to provide guidance to consumers to make environmentally responsible choices in their food consumption, to assist food supply chain stakeholders to identify the key areas for environmental improvements, and to provide policy makers with a tool for monitoring the potential impacts on climate change resulting from developments within the ...
Known for
Finnish Food | 34 N2o Emissions | Key Areas | Single Lunch Portion

Department of Teacher Education, University of Helsinki, P. O. Box 8, FI-00014 University of Helsinki, Finland

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