Prominent publications by Sushrut Sujan Thiruvengadam
Spigelman stage IV duodenal polyposis does not precede most duodenal cancer cases in patients with familial adenomatous polyposis
[ PUBLICATION ]
BACKGROUND AND AIMS: The greatest known risk factor for duodenal cancer in familial adenomatous polyposis (FAP) is Spigelman stage (SS) IV duodenal polyposis. Endoscopic surveillance is recommended in FAP patients with SS 0 to IV, and prophylactic duodenectomy should be considered in SS IV. Cancer occurs in patients without SS IV polyposis. We assessed the relationship of SS and other factors with duodenal cancer in FAP.
METHODS: We performed a case-control study on 18 FAP patients with ...
|Also Ranks for: Duodenal Cancer | familial adenomatous polyposis | spigelman stage | fap patients | endoscopic surveillance|
[ PUBLICATION ]
BACKGROUND AND AIMS: Pancreatic intraepithelial neoplasia is associated with chronic pancreatitis (CP) changes on EUS. The objective of this study was to determine whether CP changes were more common in high-risk individuals (HRIs) than in control subjects and whether these changes differed among higher-risk subsets of HRIs.
METHODS: HRIs and control subjects were identified from an endoscopy database. HRIs were defined as having predisposing mutations or a family history (FH) of ...
|Also Ranks for: Chronic Pancreatitis | pancreatic ductal | risk individuals | pancreas screening | endosonography female|
PURPOSE OF REVIEW: Gastric varices (GV) are an important complication of portal hypertension, and the current recommendation for management is beta-blocker therapy for primary prophylaxis and transjugular intrahepatic portosystemic shunt (TIPS) for active bleeding or secondary prophylaxis. Direct endoscopic injection of cyanoacrylate (CYA) glue has been investigated but has drawbacks including limited endoscopic characterization of GV and possible distal glue embolism. To this end, ...
|Also Ranks for: Gastric Varices | portal hypertension | secondary prophylaxis | embolization therapeutic | endoscopic injection|
Petrous apex masses can manifest with neurologic symptoms due to their involvement of various structures, including cranial nerves (CN) V and VI. The differential diagnosis of petrous masses is broad and includes a variety of both non-neoplastic and neoplastic lesions. We report a rare case of multiple myeloma confined to the right petrous apex, presenting with ipsilateral abducens and trigeminal nerve palsies. A 63-year-old woman presented with a 6-8 week history of facial numbness and ...
|Also Ranks for: Multiple Myeloma | cranial nerve | meckel cave | year woman|
Gene Expression Changes Accompanying the Duodenal Adenoma-Carcinoma Sequence in Familial Adenomatous Polyposis
[ PUBLICATION ]
OBJECTIVES: Duodenal cancer in familial adenomatous polyposis (FAP) arises from adenomas. Differentially expressed genes (DEGs) in the duodenal adenoma-carcinoma pathway have been identified in murine FAP models, but similar data in patients with FAP are limited. Identifying such changes may have significance in understanding duodenal polyposis therapies and identifying cancer biomarkers. We performed a genome-wide transcriptional analysis to describe the duodenal adenoma-carcinoma ...
|Also Ranks for: Gene Expression | involved cell | fold 2 | differentially expressed|
Pre-cancerous colon polyps in the young – incidental adenoma detection in average-risk persons forty and younger
[ PUBLICATION ]
Of 166 consecutive diagnostic colonoscopies performed on persons aged forty and under (excluding those at an increased risk of colon neoplasms) by a single gastroenterologist in community practice with an Adenoma Detection Rate (ADR) approaching 70% in average-risk screening colons in persons over fifty, 34 had incidentally detected colon adenomas and 38 had serrated polyps. We suggest routine tabulation of incidentally detected polyps in young people to better understand colon neoplasm ...
|Also Ranks for: Adenoma Detection | young people | colonoscopy colorectal | colonic polyps|
Sushrut Sujan Thiruvengadam: Influence Statistics
|fap duodenal cancer||#24|
|fap spigelman stage||#28|
Key People For Duodenal Cancer
Sushrut Sujan Thiruvengadam:Expert Impact
Concepts for whichSushrut Sujan Thiruvengadamhas direct influence:Duodenal cancer, Familial adenomatous polyposis, Gastric varices, Endoscopic ultrasound, Duodenal polyposis, Chronic pancreatitis, Adenomatous polyposis, Spigelman stage.
Sushrut Sujan Thiruvengadam:KOL impact
Concepts related to the work of other authors for whichfor which Sushrut Sujan Thiruvengadam has influence:Familial adenomatous polyposis, Pancreatic carcinoma, Duodenal adenomas, Patients fap, Endoscopic management, Chronic pancreatitis, Qinchuan cattle.
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